ES2156212T3 - Derivados de azabicicloheptano n-substituidos como neurolepticos, etc. - Google Patents

Derivados de azabicicloheptano n-substituidos como neurolepticos, etc.

Info

Publication number
ES2156212T3
ES2156212T3 ES95926973T ES95926973T ES2156212T3 ES 2156212 T3 ES2156212 T3 ES 2156212T3 ES 95926973 T ES95926973 T ES 95926973T ES 95926973 T ES95926973 T ES 95926973T ES 2156212 T3 ES2156212 T3 ES 2156212T3
Authority
ES
Spain
Prior art keywords
neurolepticos
azabicicloheptane
derivatives
substituted
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95926973T
Other languages
English (en)
Inventor
Gerd Steiner
Rainer Munschauer
Thomas Hoger
Liliane Unger
Hans-Jurgen Teschendorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6524943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2156212(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2156212T3 publication Critical patent/ES2156212T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/90Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C07D209/92Naphthostyrils

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE FORMULA (I), EN DONDE A, R SUP,1} Y N TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION. LOS NUEVOS COMPUESTOS ESTAN INDICADOS PARA EL TRATAMIENTO DE ENFERMEDADES.
ES95926973T 1994-08-04 1995-07-22 Derivados de azabicicloheptano n-substituidos como neurolepticos, etc. Expired - Lifetime ES2156212T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4427647A DE4427647A1 (de) 1994-08-04 1994-08-04 N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ES2156212T3 true ES2156212T3 (es) 2001-06-16

Family

ID=6524943

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95926973T Expired - Lifetime ES2156212T3 (es) 1994-08-04 1995-07-22 Derivados de azabicicloheptano n-substituidos como neurolepticos, etc.

Country Status (29)

Country Link
US (1) US5753690A (es)
EP (1) EP0775113B1 (es)
JP (1) JPH10503504A (es)
KR (1) KR970704685A (es)
CN (1) CN1064959C (es)
AT (1) ATE200482T1 (es)
AU (1) AU699021B2 (es)
BG (1) BG63632B1 (es)
CA (1) CA2196700A1 (es)
CZ (1) CZ289080B6 (es)
DE (2) DE4427647A1 (es)
DK (1) DK0775113T3 (es)
ES (1) ES2156212T3 (es)
FI (1) FI970449A7 (es)
GR (1) GR3035744T3 (es)
HR (1) HRP950437B1 (es)
HU (1) HUT77768A (es)
IL (1) IL114719A (es)
MX (1) MX9700854A (es)
NO (1) NO307376B1 (es)
NZ (1) NZ290429A (es)
PL (1) PL182810B1 (es)
PT (1) PT775113E (es)
RU (1) RU2160254C2 (es)
SI (1) SI9520086B (es)
TW (1) TW378203B (es)
UA (1) UA44736C2 (es)
WO (1) WO1996004245A1 (es)
ZA (1) ZA956476B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
ATE520659T1 (de) * 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
EP1874801A4 (en) * 2005-03-07 2009-03-25 Univ North Carolina MEANS OF INHIBITING RECA ACTIVITIES FOR THE CONTROL OF ANTIBIOTIC-SITES BACTERIAL PATHOGENESE
FR2953514B1 (fr) * 2009-12-09 2011-12-23 Servier Lab Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN112010859B (zh) * 2019-05-30 2022-07-19 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途
CN118356426A (zh) * 2023-01-18 2024-07-19 苏州旺山旺水生物医药股份有限公司 一种包含并环化合物的药物组合物及其制备方法和应用
CN120965560A (zh) * 2024-05-16 2025-11-18 澜杉(北京)生物科技有限公司 杂环烷基羧酸衍生物、中间体及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4219975A1 (de) * 1992-06-19 1993-12-23 Basf Ag Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
GB9321481D0 (en) * 1993-10-18 1993-12-08 Alcan Int Ltd Tin oxide
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
BG63632B1 (bg) 2002-07-31
RU2160254C2 (ru) 2000-12-10
AU3116595A (en) 1996-03-04
DE4427647A1 (de) 1996-02-08
HRP950437A2 (en) 1997-08-31
NZ290429A (en) 1998-02-26
CA2196700A1 (en) 1996-02-15
GR3035744T3 (en) 2001-07-31
EP0775113A1 (de) 1997-05-28
WO1996004245A1 (de) 1996-02-15
SI9520086A (en) 1997-08-31
SI9520086B (sl) 2002-02-28
FI970449A0 (fi) 1997-02-03
NO970474D0 (no) 1997-02-03
CN1156989A (zh) 1997-08-13
ZA956476B (en) 1997-02-03
EP0775113B1 (de) 2001-04-11
DK0775113T3 (da) 2001-05-07
NO970474L (no) 1997-04-01
TW378203B (en) 2000-01-01
CN1064959C (zh) 2001-04-25
ATE200482T1 (de) 2001-04-15
PL318459A1 (en) 1997-06-09
CZ31197A3 (en) 1997-10-15
FI970449L (fi) 1997-04-03
CZ289080B6 (cs) 2001-10-17
JPH10503504A (ja) 1998-03-31
UA44736C2 (uk) 2002-03-15
IL114719A (en) 2001-03-19
FI970449A7 (fi) 1997-04-03
DE59509186D1 (de) 2001-05-17
PT775113E (pt) 2001-09-28
MX9700854A (es) 1997-04-30
AU699021B2 (en) 1998-11-19
NO307376B1 (no) 2000-03-27
BG101221A (bg) 1997-08-29
US5753690A (en) 1998-05-19
HUT77768A (hu) 1998-08-28
KR970704685A (ko) 1997-09-06
HRP950437B1 (en) 2002-06-30
PL182810B1 (pl) 2002-03-29
IL114719A0 (en) 1995-11-27

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