ES2157307T3 - Composicion topica que contiene un antagonista de sustancia p. - Google Patents
Composicion topica que contiene un antagonista de sustancia p.Info
- Publication number
- ES2157307T3 ES2157307T3 ES95402502T ES95402502T ES2157307T3 ES 2157307 T3 ES2157307 T3 ES 2157307T3 ES 95402502 T ES95402502 T ES 95402502T ES 95402502 T ES95402502 T ES 95402502T ES 2157307 T3 ES2157307 T3 ES 2157307T3
- Authority
- ES
- Spain
- Prior art keywords
- irritant
- product
- composition containing
- antagonist
- substance antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
LA INVENCION SE REFIERE A UNA COMPOSICION TERAPEUTICA DE APLICACION TOPICA QUE CONTIENE AL MENOS UN PRODUCTO DE EFECTO SECUNDARIO IRRITANTE Y UN ANTAGONISTA DE SUSTANCIA P PARA REDUCIR INCLUSO ELIMINAR EL EFECTO IRRITANTE DE ESTE PRODUCTO. SE REFIERE TAMBIEN A LA UTILIZACION DE UN ANTAGONISTA DE SUSTANCIA P PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA EN LA APLICACION TOPICA QUE CONTIENE AL MENOS UN PRODUCTO DE EFECTO SECUNDARIO IRRITANTE PARA REDUCIR INCLUSO ELIMINAR EL EFECTO IRRITANTE DE ESTE PRODUCTO. EL ANTAGONISTA DE SUSTANCIA P PUEDE SER UN COMPUESTO PEPTIDICO O UN COMPUESTO NITROGENADO O UN COMPUESTO HETEROCICLICO NITROGENADO, AZUFRADO U OXIGENADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9415253A FR2728166A1 (fr) | 1994-12-19 | 1994-12-19 | Composition topique contenant un antagoniste de substance p |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2157307T3 true ES2157307T3 (es) | 2001-08-16 |
Family
ID=9469931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95402502T Expired - Lifetime ES2157307T3 (es) | 1994-12-19 | 1995-11-09 | Composicion topica que contiene un antagonista de sustancia p. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5824650A (es) |
| EP (1) | EP0722736B1 (es) |
| JP (1) | JPH08208505A (es) |
| AR (1) | AR002007A1 (es) |
| AT (1) | ATE198986T1 (es) |
| BR (1) | BR9505408A (es) |
| CA (1) | CA2165521C (es) |
| DE (1) | DE69520032T2 (es) |
| DK (1) | DK0722736T3 (es) |
| ES (1) | ES2157307T3 (es) |
| FR (1) | FR2728166A1 (es) |
| GR (1) | GR3035652T3 (es) |
| HU (1) | HU218936B (es) |
| MX (1) | MX9505182A (es) |
| PL (1) | PL311918A1 (es) |
| PT (1) | PT722736E (es) |
| RU (1) | RU2124353C1 (es) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6203803B1 (en) | 1994-12-14 | 2001-03-20 | Societe L'oreal S.A. | Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained |
| US6139850A (en) * | 1994-12-21 | 2000-10-31 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
| US7404967B2 (en) * | 1994-12-21 | 2008-07-29 | Cosmederm, Inc. | Topical product formulations containing strontium for reducing skin irritation |
| FR2732221B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
| US20040071762A1 (en) * | 1996-05-29 | 2004-04-15 | Scotia Holdings Plc | Diagnostic test for schizophrenia, using niacin |
| US7217714B1 (en) | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
| PE20001420A1 (es) | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| DE19924277A1 (de) * | 1999-05-27 | 2000-11-30 | Beiersdorf Ag | Zubereitungen von Emulsionstyp W/O mit erhöhtem Wassergehalt mit einem Gehalt an mittelpolaren Lipiden und Siliconemulgatoren und gegebenenfalls kationischen Polymeren |
| US6861397B2 (en) * | 1999-06-23 | 2005-03-01 | The Dial Corporation | Compositions having enhanced deposition of a topically active compound on a surface |
| US6107261A (en) * | 1999-06-23 | 2000-08-22 | The Dial Corporation | Compositions containing a high percent saturation concentration of antibacterial agent |
| RU2161974C1 (ru) * | 2000-01-20 | 2001-01-20 | Общество с ограниченной ответственностью "Клиника Института биорегуляции и геронтологии" | Лечебно-профилактическое средство для ухода за кожей (варианты) |
| KR100366439B1 (ko) * | 2000-02-21 | 2003-01-09 | 주식회사 대웅 | 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물 |
| US6689399B1 (en) | 2000-03-16 | 2004-02-10 | James R. Dickson | Transdermal delivery of an anti-inflammatory composition |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| GB0029018D0 (en) * | 2000-11-28 | 2001-01-10 | Strakan Group Plc | Dermatological formulations |
| ITPD20010187A1 (it) * | 2001-07-23 | 2003-01-23 | Cutech Srl | Trattamento del follicolo polifero, in particolare contro la caduta dei capelli |
| RU2190394C1 (ru) * | 2001-11-08 | 2002-10-10 | ОАО Нижегородский химико-фармацевтический завод | Фармацевтический состав, обладающий противогрибковой активностью, и способ его получения |
| US7820186B2 (en) | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
| RU2243992C2 (ru) * | 2002-03-28 | 2005-01-10 | Сорокин Валерий Николаевич | Способ получения водно-спиртового раствора и алкогольный, фармацевтический и косметический продукты, изготовленные с его использованием |
| RU2216582C2 (ru) * | 2002-01-15 | 2003-11-20 | Сорокин Валерий Николаевич | Способ получения водно-спиртового раствора и алкогольный, фармацевтический и косметический продукты, изготовленные с его использованием |
| ATE442431T1 (de) | 2002-01-15 | 2009-09-15 | Ooo Snp Ob Sopytnaya Vodno Ana | Verfahren zur herstellung einer wasser-alkohol- lísung |
| JP4473491B2 (ja) * | 2002-05-28 | 2010-06-02 | 株式会社資生堂 | 毛穴縮小剤 |
| US6723755B2 (en) | 2002-06-12 | 2004-04-20 | Piotr Chomczynski | Method of treating rosacea |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
| US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| RU2257204C2 (ru) * | 2003-08-12 | 2005-07-27 | Открытое Акционерное Общество "Фармакон" (ОАО "Фармакон") | Противогрибковая гелевая фармацевтическая композиция и способ ее получения |
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| US6902723B2 (en) * | 2003-08-14 | 2005-06-07 | The Gillette Company | Enhanced efficacy antiperspirant compositions containing strontium |
| US7812057B2 (en) * | 2004-08-25 | 2010-10-12 | Molecular Research Center, Inc. | Cosmetic compositions |
| US7872050B2 (en) * | 2005-03-14 | 2011-01-18 | Yaupon Therapeutics Inc. | Stabilized compositions of volatile alkylating agents and methods of using thereof |
| US8501818B2 (en) * | 2005-03-14 | 2013-08-06 | Ceptaris Therapeutics, Inc. | Stabilized compositions of alkylating agents and methods of using same |
| US20110039943A1 (en) * | 2005-03-14 | 2011-02-17 | Robert Alonso | Methods for treating skin disorders with topical nitrogen mustard compositions |
| WO2007039825A2 (en) | 2005-05-09 | 2007-04-12 | Foamix Ltd. | Saccharide foamable compositions |
| PL1888033T3 (pl) * | 2005-06-09 | 2014-09-30 | Meda Ab | Sposób i kompozycja do leczenia chorób zapalnych |
| WO2007062060A2 (en) | 2005-11-22 | 2007-05-31 | Ted Reid | Methods and compositions using substance p to promote wound healing |
| US8426386B2 (en) | 2006-10-16 | 2013-04-23 | Lion Corporation | NK1 receptor antagonist composition |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
| CA2687063C (en) * | 2007-05-11 | 2017-04-04 | Aloebiotics Research Labs, Inc. | Aloe preparation for skin enhancement |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| EP2242476A2 (en) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| TR201907794T4 (tr) * | 2008-03-27 | 2019-06-21 | Helsinn Healthcare Sa | Alkilleyici maddelerin stabilize edilmiş bileşimleri ve bunları kullanım yöntemleri. |
| EP2177208A1 (en) * | 2008-10-17 | 2010-04-21 | Ferrer Internacional, S.A. | Pharmaceutical topical compositions |
| US7833829B2 (en) * | 2008-10-28 | 2010-11-16 | Honeywell International Inc. | MEMS devices and methods of assembling micro electromechanical systems (MEMS) |
| US20120077803A1 (en) * | 2009-02-24 | 2012-03-29 | Novartis Ag | Uses Of NK Receptor Antagonists |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| RU2485955C2 (ru) * | 2010-11-17 | 2013-06-27 | Леонид Леонидович Клопотенко | Фармацевтическая композиция, содержащая флуконазол, и/или кетоконазол, и/или тербинафин и липосомы для местного применения |
| KR101729096B1 (ko) | 2012-03-21 | 2017-04-21 | 코스메덤 바이오사이언스, 인코퍼레이티드 | 통증, 가려움증 및 염증을 치료하기 위한 국소 투여된 스트론튬-함유 복합체 |
| US11235002B2 (en) | 2015-08-21 | 2022-02-01 | Galleon Labs Llc | Strontium based compositions and formulations for pain, pruritus, and inflammation |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US11708135B2 (en) | 2018-05-30 | 2023-07-25 | Philip John Milanovich | Waste management system |
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| UA41251C2 (uk) | 1990-01-04 | 2001-09-17 | Пфайзер, Інк. | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі |
| EP0439640B1 (de) * | 1990-01-29 | 1993-09-15 | WOGEPHARM GmbH | Verfahren zur Herstellung von Mitteln zur Therapie von Hauterkrankungen |
| US5321032A (en) | 1990-02-15 | 1994-06-14 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compounds and pharmaceutical compositions thereof |
| US5344532A (en) | 1990-03-09 | 1994-09-06 | Joseph Adrian A | Ultrasonic energy producing device |
| FR2662607B1 (fr) * | 1990-05-30 | 1992-08-28 | Oreal | Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 . |
| CA2080249C (en) | 1990-05-31 | 1996-11-19 | Dennis M. Godek | Preparation of substituted piperidines |
| JPH072740B2 (ja) | 1990-06-01 | 1995-01-18 | フアイザー・インコーポレイテツド | 3―アミノ―2―アリールキヌクリジン |
| DK0498069T3 (da) | 1990-12-21 | 1995-12-04 | Fujisawa Pharmaceutical Co | Ny anvendelse af peptidderivat |
| EP0566589A1 (en) | 1991-01-10 | 1993-10-27 | Pfizer Inc. | N-alkyl quinuclidinium salts as substance p antagonists |
| EP0499313B1 (en) | 1991-02-11 | 1997-06-11 | MERCK SHARP & DOHME LTD. | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| ES2065175T3 (es) | 1991-03-01 | 1995-02-01 | Pfizer | Derivados de 1-azabiciclo(3.2.2)nonan-3-amina. |
| SK284565B6 (sk) | 1991-03-26 | 2005-06-02 | Pfizer Inc. | Spôsob prípravy substituovaných piperidínov |
| FR2677361A1 (fr) | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676443B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
| FR2676442B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676446B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676447B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole et leur preparation. |
| PL171921B1 (pl) | 1991-05-22 | 1997-06-30 | Pfizer | Sposób wytwarzania nowych pochodnych podstawionej 3-aminochinuklidyny PL PL PL PL PL |
| GB9113219D0 (en) | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
| FI990419A7 (fi) | 1991-06-20 | 1999-02-26 | Pfizer | Typpeä sisältävien hetrosyklisten yhdisteiden fluorialkoksibentsyyliaminojohdannaiset |
| TW202432B (es) | 1991-06-21 | 1993-03-21 | Pfizer | |
| US5288730A (en) | 1991-06-24 | 1994-02-22 | Merck Sharp & Dohme Limited | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| US5472978A (en) | 1991-07-05 | 1995-12-05 | Merck Sharp & Dohme Ltd. | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
| JPH06509332A (ja) | 1991-07-05 | 1994-10-20 | メルク シヤープ エンド ドーム リミテツド | 芳香族化合物、それらを含む医薬組成物、及び治療におけるそれらの使用 |
| WO1993001165A2 (en) | 1991-07-10 | 1993-01-21 | Merck Sharp & Dohme Limited | Aromatic compounds, compositions containing them and their use in therapy |
| US5495047A (en) | 1991-07-10 | 1996-02-27 | Merck, Sharp & Dohme (Ltd.) | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| MY110227A (en) | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| EP0600952B1 (en) | 1991-08-20 | 1996-04-17 | MERCK SHARP & DOHME LTD. | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
| CZ59394A3 (en) | 1991-09-26 | 1994-11-16 | Pfizer | Condensed tricyclic heterocycles containing nitrogen as antagonists of p substance receptor, process of their preparation, intermediates, pharmaceutical preparations in which they are comprised and use |
| JP2553020B2 (ja) | 1991-11-07 | 1996-11-13 | 吉富製薬株式会社 | キヌクリジン化合物およびその医薬用途 |
| DK0613458T3 (da) | 1991-11-12 | 1998-02-09 | Pfizer | Acykliske ethylendiaminderivater som substans P receptorantagonister |
| CA2083891A1 (en) | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Heterocyclic compounds, compositions containing them and their use in therapy |
| US5569662A (en) * | 1992-03-23 | 1996-10-29 | Pfizer Inc. | Quinuclidine derivatives as substance P antagonists |
| DE4227203C2 (de) * | 1992-08-17 | 1994-03-24 | Kao Corp Gmbh | Mittel und Verfahren zur Haarbehandlung |
| JP2656699B2 (ja) | 1992-10-21 | 1997-09-24 | ファイザー製薬株式会社 | 置換ベンジルアミノキヌクリジン |
| US5716625A (en) * | 1994-12-21 | 1998-02-10 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
-
1994
- 1994-12-19 FR FR9415253A patent/FR2728166A1/fr active Granted
-
1995
- 1995-11-09 EP EP95402502A patent/EP0722736B1/fr not_active Revoked
- 1995-11-09 DE DE69520032T patent/DE69520032T2/de not_active Revoked
- 1995-11-09 ES ES95402502T patent/ES2157307T3/es not_active Expired - Lifetime
- 1995-11-09 DK DK95402502T patent/DK0722736T3/da active
- 1995-11-09 AT AT95402502T patent/ATE198986T1/de not_active IP Right Cessation
- 1995-11-09 PT PT95402502T patent/PT722736E/pt unknown
- 1995-12-11 MX MX9505182A patent/MX9505182A/es unknown
- 1995-12-13 BR BR9505408A patent/BR9505408A/pt active Search and Examination
- 1995-12-15 AR ARP950100577A patent/AR002007A1/es unknown
- 1995-12-18 RU RU95121151A patent/RU2124353C1/ru active
- 1995-12-18 HU HU9503623A patent/HU218936B/hu not_active IP Right Cessation
- 1995-12-18 CA CA002165521A patent/CA2165521C/fr not_active Expired - Fee Related
- 1995-12-18 PL PL95311918A patent/PL311918A1/xx unknown
- 1995-12-18 JP JP7329297A patent/JPH08208505A/ja active Pending
- 1995-12-19 US US08/575,682 patent/US5824650A/en not_active Expired - Lifetime
-
1998
- 1998-06-15 US US09/094,558 patent/US5972892A/en not_active Expired - Lifetime
-
2001
- 2001-03-29 GR GR20010400502T patent/GR3035652T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08208505A (ja) | 1996-08-13 |
| DE69520032D1 (de) | 2001-03-08 |
| EP0722736B1 (fr) | 2001-01-31 |
| US5824650A (en) | 1998-10-20 |
| ATE198986T1 (de) | 2001-02-15 |
| AR002007A1 (es) | 1998-01-07 |
| BR9505408A (pt) | 1997-10-28 |
| DE69520032T2 (de) | 2001-05-23 |
| EP0722736A1 (fr) | 1996-07-24 |
| CA2165521A1 (fr) | 1996-06-20 |
| MX9505182A (es) | 1997-02-28 |
| PL311918A1 (en) | 1996-06-24 |
| HU218936B (hu) | 2001-01-29 |
| CA2165521C (fr) | 2002-07-16 |
| DK0722736T3 (da) | 2001-04-02 |
| FR2728166A1 (fr) | 1996-06-21 |
| PT722736E (pt) | 2001-05-31 |
| GR3035652T3 (en) | 2001-06-29 |
| HU9503623D0 (en) | 1996-02-28 |
| US5972892A (en) | 1999-10-26 |
| RU2124353C1 (ru) | 1999-01-10 |
| FR2728166B1 (es) | 1997-02-07 |
| HUT74830A (en) | 1997-02-28 |
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