ES2157426T3 - Modulacion de las propiedades de union de coparticipes de union de un acido nucleico. - Google Patents

Modulacion de las propiedades de union de coparticipes de union de un acido nucleico.

Info

Publication number
ES2157426T3
ES2157426T3 ES96906731T ES96906731T ES2157426T3 ES 2157426 T3 ES2157426 T3 ES 2157426T3 ES 96906731 T ES96906731 T ES 96906731T ES 96906731 T ES96906731 T ES 96906731T ES 2157426 T3 ES2157426 T3 ES 2157426T3
Authority
ES
Spain
Prior art keywords
union
nucleic acid
coparticipes
modulation
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96906731T
Other languages
English (en)
Inventor
Henrik Orum
Ane-Ullerup Lester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PNA Diagnostics ApS Denmark
Original Assignee
PNA Diagnostics ApS Denmark
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PNA Diagnostics ApS Denmark filed Critical PNA Diagnostics ApS Denmark
Application granted granted Critical
Publication of ES2157426T3 publication Critical patent/ES2157426T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Steroid Compounds (AREA)

Abstract

UN METODO PARA DETERMINAR ESPECIFICAMENTE LA PRESENCIA DE UNA DIANA MEDIANTE LA PUESTA EN CONTACTO DE DICHA DIANA EN PRESENCIA DE OTRAS DIANAS CON UNA SONDA CAPAZ DE UNIRSE A DICHA DIANA PARA FORMAR UN COMPLEJO ENTRE DICHA DIANA Y DICHA SONDA, EN EL QUE LA PUESTA EN CONTACTO SE REALIZA EN PRESENCIA DE UN COMPUESTO QUE AUMENTA LA ESPECIFICIDAD DE DICHA UNION O BIEN EL COMPLEJO FORMADO SE PONE EN CONTACTO CON UN COMPUESTO QUE AUMENTA LA ESPECIFICIDAD DE DICHA UNION. ESTE METODO OFRECE LA POSIBILIDAD DE DISCRIMINAR MEJOR ENTRE LAS SECUENCIAS DE ACIDOS NUCLEICOS RELACIONADOS EN LOS ENSAYOS DIAGNOSTICOS.
ES96906731T 1995-03-04 1996-03-04 Modulacion de las propiedades de union de coparticipes de union de un acido nucleico. Expired - Lifetime ES2157426T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95103122 1995-03-04
EP95118843 1995-11-30

Publications (1)

Publication Number Publication Date
ES2157426T3 true ES2157426T3 (es) 2001-08-16

Family

ID=26138490

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96906731T Expired - Lifetime ES2157426T3 (es) 1995-03-04 1996-03-04 Modulacion de las propiedades de union de coparticipes de union de un acido nucleico.

Country Status (8)

Country Link
US (2) US7682786B1 (es)
EP (1) EP0815259B1 (es)
JP (1) JPH11501511A (es)
AT (1) ATE201453T1 (es)
DE (1) DE69612970T2 (es)
DK (1) DK0815259T3 (es)
ES (1) ES2157426T3 (es)
WO (1) WO1996027679A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2004104196A1 (ja) * 2003-05-20 2006-07-20 Ｇ＆Ｇサイエンス株式会社 緩衝剤組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687645T2 (de) * 1986-01-07 1993-05-27 Gen Probe Inc Verfahren der beschleunigten wiederassoziation der nukleinsaeure.
US5599667A (en) * 1987-03-02 1997-02-04 Gen-Probe Incorporated Polycationic supports and nucleic acid purification separation and hybridization
US5030557A (en) * 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
AU6144590A (en) 1989-07-24 1991-03-11 Microprobe Corporation Lactam-containing compositions and methods useful for the hybridization of nucleic acids
WO1991006679A1 (en) * 1989-10-24 1991-05-16 Stratagene An improved method for hybridizing nucleic acids using single-stranded nucleic acid binding protein
JPH05503011A (ja) * 1989-12-01 1993-05-27 ザ　ボード　オブ　トラスティーズ　オブ　リーランド　スタンフォード　ジュニア　ユニバーシティ 高特異性分子集成体の促進
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
DE4216949C2 (de) * 1992-05-22 1997-07-24 Christoph Prof Dr Dr Cremer Nichtenzymatisches Verfahren zur In-situ-Hybridisierung bei spezifischen Proben
AU7208394A (en) 1993-06-17 1995-01-17 Research Foundation Of The State University Of New York, The Improved nucleic acid reactions
GB2285445A (en) 1993-12-06 1995-07-12 Pna Diagnostics As Protecting nucleic acids and methods of analysis

Also Published As

Publication number Publication date
DE69612970D1 (de) 2001-06-28
EP0815259A1 (en) 1998-01-07
EP0815259B1 (en) 2001-05-23
US7682786B1 (en) 2010-03-23
DE69612970T2 (de) 2001-11-22
JPH11501511A (ja) 1999-02-09
WO1996027679A1 (en) 1996-09-12
US20090325301A1 (en) 2009-12-31
ATE201453T1 (de) 2001-06-15
DK0815259T3 (da) 2001-09-17

Similar Documents

Publication Publication Date Title
FI900602A0 (fi) Bestaemning.
DE69939896D1 (de) Methoden zur detektion von nukleinsäuren unter verwendung von zymogenen und dazugehörige kits
SE8800864D0 (sv) Method of assaying of nucleic acids, a reagent combination and kit therefore
ATE348191T1 (de) Polynukleotid-sequenzassay
MX9704842A (es) Deecction de secuencias del acido nucleico, que emplean sondas de amplificacion.
DE69531309D1 (de) Entwurf diskontinuierlicher sonden unter verwendung von hybritopemapping
DE69535802D1 (de) Genetische veränderungen, die mit lungencarzinomen korrelieren
AU582293B2 (en) Heterogeneous specific binding assay employing an aggregatable binding reagent
ATE206764T1 (de) Verfahren zum sensitiven nachweis von nukleinsäuren
FR2602592B1 (fr) Utilisation du systeme enzymatique xanthine-oxydase en immuno-analyse, procedes de dosage correspondants et coffrets de reactifs necessaires pour la mise en oeuvre de ces procedes.
DE60043944D1 (de) Zytokin zcyt018
BR9609390A (pt) Ensaio quimiluminescente de ligação específica com não-separação
EP1007570A4 (en) Monospecific antibody reactive with fibrinogen and fibrinopeptide b
ES2157426T3 (es) Modulacion de las propiedades de union de coparticipes de union de un acido nucleico.
ATE449868T1 (de) Methoden, testsätze und kompositionen zur detektion und quantifizierung von zielsequenzen
DE69924128D1 (de) Verfahren zur erkennung von verbindungen,die die wechselwirkung von rna und rna-bindungsproteinen beinflussen
ATE323286T1 (de) Verfahren zum bestimmen von autoantikörpern
DE60109733D1 (de) Verfahren zur immobilisierung von affinen reagentien an hydrophoben festphasen
EA200100452A1 (ru) Анализ на токсины, имеющие мишень фосфатазу
GR3005459T3 (es)
SE9502765D0 (sv) Analysförfarande
WO2001098530A3 (en) Interaction of tbx2 and the arf promoter in cell cycle regulator assays

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 815259

Country of ref document: ES