ATE348191T1 - Polynukleotid-sequenzassay - Google Patents

Polynukleotid-sequenzassay

Info

Publication number
ATE348191T1
ATE348191T1 AT01950861T AT01950861T ATE348191T1 AT E348191 T1 ATE348191 T1 AT E348191T1 AT 01950861 T AT01950861 T AT 01950861T AT 01950861 T AT01950861 T AT 01950861T AT E348191 T1 ATE348191 T1 AT E348191T1
Authority
AT
Austria
Prior art keywords
sample
polynucleotide sequence
disclosed
ligation
target sequence
Prior art date
Application number
AT01950861T
Other languages
English (en)
Inventor
Wanli Bi
Kenneth J Livak
Will Bloch
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE348191T1 publication Critical patent/ATE348191T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6862Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT01950861T 2000-07-03 2001-07-03 Polynukleotid-sequenzassay ATE348191T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21651400P 2000-07-03 2000-07-03

Publications (1)

Publication Number Publication Date
ATE348191T1 true ATE348191T1 (de) 2007-01-15

Family

ID=22807344

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01950861T ATE348191T1 (de) 2000-07-03 2001-07-03 Polynukleotid-sequenzassay

Country Status (8)

Country Link
US (2) US6511810B2 (de)
EP (1) EP1358350B1 (de)
JP (1) JP2004507230A (de)
AT (1) ATE348191T1 (de)
AU (1) AU2001271816B9 (de)
CA (1) CA2415125A1 (de)
DE (1) DE60125243T2 (de)
WO (1) WO2002002823A2 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US8076063B2 (en) * 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US20030129666A1 (en) * 2001-01-09 2003-07-10 Mitsubishi Pharma Corporation Novel proteome analysis method and devices therefor
AU2003269908A1 (en) * 2002-07-15 2004-02-02 Illumina, Inc. Multiplex nucleic acid reactions
AU2003272924B2 (en) * 2002-10-04 2008-05-15 Protosera Inc. Plate for mass spectrometry, process for preparing the same and use thereof
US20050053957A1 (en) * 2002-11-19 2005-03-10 Applera Corporation Polynucleotide sequence detection assays
WO2004046343A2 (en) * 2002-11-19 2004-06-03 Applera Corporation Polynucleotide sequence detection assays and analysis
WO2005001129A2 (en) * 2003-06-06 2005-01-06 Applera Corporation Mobility cassettes
US20050032113A1 (en) * 2003-07-17 2005-02-10 Mitsubishi Pharma Corporation Membrane protein library for proteome analysis and method for preparing same
US7368239B2 (en) 2003-08-29 2008-05-06 Applera Corporation Method and materials for polyamine catalyzed bisulfite conversion of cytosine to uracil
US7534873B2 (en) * 2003-08-29 2009-05-19 Applied Biosystems, Llc Method and materials for quaternary amine catalyzed bisulfite conversion of cytosine to uracil
US7262013B2 (en) * 2003-08-29 2007-08-28 Applera Corporation Bisulfite method
US7371526B2 (en) 2003-08-29 2008-05-13 Applera Corporation Method and materials for bisulfite conversion of cytosine to uracil
US7445898B2 (en) 2004-04-01 2008-11-04 Bio-Rad Laboratories, Inc. Quantitative amplification with a labeled probe and 3′ to 5′ exonuclease activity
US7517978B1 (en) * 2004-04-14 2009-04-14 Applied Biosystems, Llc Modified oligonucleotides and applications thereof
WO2005123913A2 (en) * 2004-06-09 2005-12-29 Nustar Laboratory Reversibly modified thermostable enzyme compositions and methods of making and using the same
US20060029953A1 (en) * 2004-06-29 2006-02-09 Applera Corporation Methods and kits comprising amplification and ligation for analyzing target polynucleotide sequences
US20060019289A1 (en) * 2004-06-30 2006-01-26 Applera Corporation Compositions and methods for gene expression analysis
US20060234252A1 (en) * 2004-07-02 2006-10-19 Applera Corporation Methods and kits for methylation detection
US7658288B2 (en) * 2004-11-08 2010-02-09 Applied Biosystems, Llc Bisulfite conversion reagent
JP2008535518A (ja) * 2005-04-14 2008-09-04 アプレラ コーポレイション プソイドイソシトシン核酸塩基誘導体を含む3’改変オリゴヌクレオチド、およびプライマーまたはプローブとしてのその適用
US20070087360A1 (en) * 2005-06-20 2007-04-19 Boyd Victoria L Methods and compositions for detecting nucleotides
US20070099211A1 (en) * 2005-07-15 2007-05-03 Vissarion Aivazachvili Detection of nucleic acid amplification
US20070212704A1 (en) 2005-10-03 2007-09-13 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
CA2651815A1 (en) 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
CN106566855B (zh) * 2006-07-31 2021-11-09 苏州新海生物科技股份有限公司 使用可逆修饰寡核苷酸扩增核酸
US9045522B2 (en) 2006-07-31 2015-06-02 Wanli Bi Nucleic acid amplification using a reversibly modified oligonucleotide
AU2007281535A1 (en) 2006-08-01 2008-02-07 Applied Biosystems, Llc. Detection of analytes and nucleic acids
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
US8008010B1 (en) 2007-06-27 2011-08-30 Applied Biosystems, Llc Chimeric oligonucleotides for ligation-enhanced nucleic acid detection, methods and compositions therefor
AU2009205523A1 (en) * 2008-01-14 2009-07-23 Applied Biosystems, Llc Compositions, methods, and kits for detecting ribonucleic acid
JP5588970B2 (ja) 2008-05-27 2014-09-10 ダコ・デンマーク・エー/エス ハイブリダイゼーション組成物及び方法
US9303287B2 (en) * 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
US9834815B2 (en) 2009-03-25 2017-12-05 Life Technologies Corporation Discriminatory positive/extraction control DNA
CA2757300C (en) * 2009-04-01 2018-01-09 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (clpa)
US20110165568A1 (en) 2009-12-31 2011-07-07 Life Technologies Corporation Sequences of e.coli 055:h7 genome
WO2012003330A2 (en) * 2010-06-30 2012-01-05 Stratos Genomics, Inc Multiplexed identification of nucleic acid sequences
WO2012145557A1 (en) 2011-04-19 2012-10-26 Life Technologies Corporation Compositions and methods for detecting and identifying salmonella enterica strains
US9745616B2 (en) 2011-05-17 2017-08-29 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
EP2721170A2 (de) 2011-06-17 2014-04-23 Life Technologies Corporation Zusammensetzungen und verfahren für den nachweis von cronobacter spp. und cronobacter-spezies und stämmen
US10662465B2 (en) 2011-09-30 2020-05-26 Agilent Technologies, Inc. Hybridization compositions and methods using formamide
US11118226B2 (en) 2011-10-21 2021-09-14 Agilent Technologies, Inc. Hybridization compositions and methods
EP2798086B1 (de) * 2011-12-28 2018-09-05 Ricardo Mancebo Reagenzien und verfahren für eine autoligationskettenreaktion
WO2013106807A1 (en) * 2012-01-13 2013-07-18 Curry John D Scalable characterization of nucleic acids by parallel sequencing
SG11201404899VA (en) 2012-02-14 2014-10-30 Univ Cornell Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions
US9990464B1 (en) 2012-10-09 2018-06-05 Pall Corporation Label-free biomolecular interaction analysis using a rapid analyte dispersion injection method
WO2015071552A1 (en) * 2013-11-18 2015-05-21 Teknologian Tutkimuskeskus Vtt Multi-unit probes with high specificity and a method of designing the same
KR101598398B1 (ko) * 2014-01-08 2016-02-29 (주)제노텍 5''-플랩 엔도뉴클레이즈 활성의 억제를 이용하여 실시간 중합효소 연쇄반응으로 돌연변이 유전자를 검사하는 방법
CN106879252B (zh) 2014-06-10 2020-07-17 德克斯特里蒂诊断公司 用于收集和稳定生物样品的装置及方法
NL2013857B1 (en) 2014-11-21 2016-10-11 Piculet Biosciences Tech B V Self-assembled bivalent ligand complex (SABLC) libraries and methods for screening such libraries.
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
US10876148B2 (en) 2018-11-14 2020-12-29 Element Biosciences, Inc. De novo surface preparation and uses thereof
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
CN115698282A (zh) 2020-01-13 2023-02-03 福路伦特生物科学公司 单细胞测序
US11866782B2 (en) 2020-03-16 2024-01-09 Fluent Biosciences Inc. Multi-omic analysis in monodisperse droplets
WO2021195169A1 (en) 2020-03-24 2021-09-30 Fluent Biosciences Inc. Viral detection using template emulsification
EP4182477A4 (de) 2020-07-15 2024-09-11 Fluent Biosciences Inc. Abgestufte ligationsoligos
WO2022251445A1 (en) * 2021-05-28 2022-12-01 Fluent Biosciences Inc. Spatial transcriptomics in pips
US12534721B2 (en) 2022-10-06 2026-01-27 Illumina, Inc. Quantitative detection and analysis of moleculesip

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5573907A (en) 1990-01-26 1996-11-12 Abbott Laboratories Detecting and amplifying target nucleic acids using exonucleolytic activity
CA2035010C (en) 1990-01-26 1996-12-10 Keith C. Backman Method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5516663A (en) * 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5494810A (en) * 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5994069A (en) 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
EP0654093B1 (de) * 1992-08-03 2001-01-03 Abbott Laboratories Nachweis und amplifikation bestimmter nukleinsäuren mittels exonukleolytischer aktivität
ES2185719T3 (es) * 1994-12-23 2003-05-01 Dade Behring Inc Deteccion de acidos nucleicos por formacion de un producto catalizada por diana.
ATE414793T1 (de) 1996-01-24 2008-12-15 Third Wave Tech Inc Invasive spaltung von nukleinsäuren
US5985557A (en) 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
EP2369007B1 (de) * 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Erkennung von Nukleinsäuresequenz-Unterschieden mittels der gleichzeitigen Ligaseerkennungs- und Polymerasekettenreaktion
US6312892B1 (en) * 1996-07-19 2001-11-06 Cornell Research Foundation, Inc. High fidelity detection of nucleic acid differences by ligase detection reaction
CA2273204C (en) 1996-11-29 2008-10-14 Third Wave Technologies, Inc. Fen-1 endonucleases, mixtures and cleavage methods
WO2000036152A1 (en) * 1998-12-14 2000-06-22 Li-Cor, Inc. A system and methods for nucleic acid sequencing of single molecules by polymerase synthesis

Also Published As

Publication number Publication date
EP1358350A2 (de) 2003-11-05
US20020150904A1 (en) 2002-10-17
AU7181601A (en) 2002-01-14
EP1358350B1 (de) 2006-12-13
US6511810B2 (en) 2003-01-28
AU2001271816B9 (en) 2007-05-24
WO2002002823A2 (en) 2002-01-10
AU2001271816B2 (en) 2007-03-08
WO2002002823A3 (en) 2003-08-28
DE60125243D1 (de) 2007-01-25
JP2004507230A (ja) 2004-03-11
US20040005585A1 (en) 2004-01-08
CA2415125A1 (en) 2002-01-10
DE60125243T2 (de) 2007-05-31

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