ES2157524T3 - Diselenuros y selenosulfuros utilizables como agentes antioxidantes. - Google Patents

Diselenuros y selenosulfuros utilizables como agentes antioxidantes.

Info

Publication number
ES2157524T3
ES2157524T3 ES97204070T ES97204070T ES2157524T3 ES 2157524 T3 ES2157524 T3 ES 2157524T3 ES 97204070 T ES97204070 T ES 97204070T ES 97204070 T ES97204070 T ES 97204070T ES 2157524 T3 ES2157524 T3 ES 2157524T3
Authority
ES
Spain
Prior art keywords
selenosulfures
antioxidant agents
diselenuros
compounds
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97204070T
Other languages
English (en)
Inventor
Catherine Tailhan-Lomont
Irene Erdelmeier
Marc Moutet
Jean Chaudiere
Jean-Claude Yadan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxis Isle of Man Ltd
Original Assignee
Oxis Isle of Man Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxis Isle of Man Ltd filed Critical Oxis Isle of Man Ltd
Application granted granted Critical
Publication of ES2157524T3 publication Critical patent/ES2157524T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00—Compounds containing selenium
    • C07C391/02—Compounds containing selenium having selenium atoms bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

LOS OBJETIVOS DE LA PRESENTE INVENCION SON: - COMPUESTOS NUEVOS DE ORGANOSELENIO, DISELENIDOS Y SELENOSULFUROS AROMATICOS ; - EL USO DE DICHOS COMPUESTOS NUEVOS COMO AGENTES ANTIOXIDANTES; LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN; - UN METODO DE PREPARACION DE DICHOS COMPUESTOS NUEVOS. ESTOS COMPUESTOS NUEVOS CICLICOS DE ORGANOSELENIO TIENEN LA FORMULA GENERAL (I):
ES97204070T 1996-12-27 1997-12-23 Diselenuros y selenosulfuros utilizables como agentes antioxidantes. Expired - Lifetime ES2157524T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9616103A FR2757857B1 (fr) 1996-12-27 1996-12-27 Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques

Publications (1)

Publication Number Publication Date
ES2157524T3 true ES2157524T3 (es) 2001-08-16

Family

ID=9499211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97204070T Expired - Lifetime ES2157524T3 (es) 1996-12-27 1997-12-23 Diselenuros y selenosulfuros utilizables como agentes antioxidantes.

Country Status (10)

Country Link
US (2) US5973009A (es)
EP (1) EP0850924B1 (es)
JP (1) JPH10330355A (es)
AT (1) ATE199710T1 (es)
AU (1) AU736842B2 (es)
CA (1) CA2225903C (es)
DE (1) DE69704255T2 (es)
DK (1) DK0850924T3 (es)
ES (1) ES2157524T3 (es)
FR (1) FR2757857B1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757857B1 (fr) * 1996-12-27 1999-04-23 Oxis International Sa Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques
AU2001237939A1 (en) * 2000-02-08 2001-08-20 Gulgun Tezel Methods for treating glaucoma
US6852353B2 (en) 2000-08-24 2005-02-08 Novartis Ag Process for surface modifying substrates and modified substrates resulting therefrom
FR2831822A1 (fr) * 2001-11-07 2003-05-09 Inst Nat Sante Rech Med Utilisation therapeutique de derives 4-mercapto- ou 4-seleno-imidazoles
US20030118329A1 (en) * 2001-12-21 2003-06-26 Pere Obrador Video indexing using high resolution still images
CA2397684A1 (en) * 2002-08-12 2004-02-12 Michael P. Murphy Mitochondrially targeted antioxidants
AU2004314731B2 (en) * 2004-01-20 2011-07-07 The Board Of Regents Of The University Of Oklahoma Compositions and methods of treatment for inflammatory diseases
US20050201989A1 (en) * 2004-02-19 2005-09-15 St. Camillus Medical, Inc. Compositions and methods for ex vivo preservation of blood vessels for vascular grafts using inhibitors of tumor necrosis factor-alpha
US7586003B2 (en) * 2005-07-14 2009-09-08 Zinpro Corporation Derivatives of seleno-amino acids
WO2007044641A2 (en) * 2005-10-06 2007-04-19 University Technologies International Inc. Glutathione peroxidase mimetics and uses thereof
RU2307648C1 (ru) * 2006-01-17 2007-10-10 Юрий Алексеевич Новицкий Способ получения средства, обладающего иммунотропным действием
RU2315597C1 (ru) * 2006-03-31 2008-01-27 Юрий Алексеевич Новицкий Средство, обладающее ангиотропным действием (варианты)
BRPI1101935B1 (pt) * 2011-04-15 2017-12-12 Universidade Federal De Minas Gerais Antioxidant composition for preservation of organs and fabrics
CN103917899B (zh) 2011-10-12 2018-04-03 诺华股份有限公司 通过涂布制备uv吸收性眼用透镜的方法
US10338408B2 (en) 2012-12-17 2019-07-02 Novartis Ag Method for making improved UV-absorbing ophthalmic lenses
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
EP3262942A1 (de) * 2016-06-27 2018-01-03 Evonik Degussa GmbH Selenodiaryle zur anwendung als mikrobizid sowie als arzneimittel
CN113773418B (zh) * 2021-10-22 2024-03-08 扬州大学 一种以二硒醚为硒源的聚苯乙烯硒化方法
US11920060B1 (en) * 2023-08-21 2024-03-05 King Faisal University Multifunctional diorganyl diselenide tethered cellulose as a corrosion inhibitor of stainless steel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311853A (en) * 1979-02-06 1982-01-19 The Radiochemical Centre Limited Selenium derivatives of thyroxine and tri-iodothyronine
IT1161213B (it) * 1983-03-08 1987-03-18 Fcn Srl Composizioni farmaceutiche ad attivita' antineoplastica
US4613468A (en) * 1984-01-12 1986-09-23 Gte Laboratories Incorporated Method for preparing aromatic and olefinic organoselenium and organotellurium compounds
DE3568775D1 (en) * 1984-06-22 1989-04-20 Nattermann A & Cie S-(carbamoyl-phenylselenyl) derivatives of glutathion and of amino mercaptocarboxylic acids, process for their preparation and pharmaceutical preparations containing them
DE3626554A1 (de) * 1986-08-06 1988-02-18 Nattermann A & Cie Diselenobis-benzoesaeureamide primaerer heterocyclischer amine, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische praeparate
US5128365A (en) * 1989-07-19 1992-07-07 The Trustees Of Columbia University In The City Of New York Compounds having glutathione peroxidase activity and use thereof
FR2718441B1 (fr) * 1994-04-07 1996-06-28 Bioxytech Nouveaux composés de structure benzisoséléna-zoline et -zine, leur procédé de préparation et leurs applications thérapeutiques.
FR2757857B1 (fr) * 1996-12-27 1999-04-23 Oxis International Sa Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques

Also Published As

Publication number Publication date
CA2225903A1 (en) 1998-06-27
US6040328A (en) 2000-03-21
FR2757857B1 (fr) 1999-04-23
DE69704255D1 (de) 2001-04-19
EP0850924A1 (en) 1998-07-01
EP0850924B1 (en) 2001-03-14
JPH10330355A (ja) 1998-12-15
DE69704255T2 (de) 2001-09-20
AU5274098A (en) 1998-07-02
CA2225903C (en) 2009-05-26
US5973009A (en) 1999-10-26
FR2757857A1 (fr) 1998-07-03
DK0850924T3 (da) 2001-07-16
AU736842B2 (en) 2001-08-02
ATE199710T1 (de) 2001-03-15

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