ES2161466T3 - Procedimientos enzimaticos para la obtencion de (s)-cianhidrinas. - Google Patents

Procedimientos enzimaticos para la obtencion de (s)-cianhidrinas.

Info

Publication number
ES2161466T3
ES2161466T3 ES97927041T ES97927041T ES2161466T3 ES 2161466 T3 ES2161466 T3 ES 2161466T3 ES 97927041 T ES97927041 T ES 97927041T ES 97927041 T ES97927041 T ES 97927041T ES 2161466 T3 ES2161466 T3 ES 2161466T3
Authority
ES
Spain
Prior art keywords
lazella
canhydrines
obtaining
cyanohidrine
aldehido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97927041T
Other languages
English (en)
Inventor
Gerald Kirchner
Irma Wirth
Christian Werenka
Herfried Griengl
Michael Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
DSM Fine Chemicals Austria Nfg GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3479966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2161466(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM Fine Chemicals Austria Nfg GmbH and Co KG filed Critical DSM Fine Chemicals Austria Nfg GmbH and Co KG
Application granted granted Critical
Publication of ES2161466T3 publication Critical patent/ES2161466T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO EN ENANTIOSELECTIVO PARA LA PREPARACION DEL (S)- EN ALDEHIDO DE UNA CIANOHIDRINA OPTICAMENTE ACTIVA HACIENDO REACCIONAR UN ALDEHIDO O CETONA CON UN DONANTE DE GRUPO DEL CIANURO. DE ACUERDO CON ESTE PROCEDIMIENTO, EL ALDEHIDO O LA CETONA SE HACE REACCIONAR CON UN DONANTE DEL GRUPO CIANURO Y UN DILUYENTE ORGANICO, EN PRESENCIA DE UNA LIASA DE (S)HIDROXINITRILO RECOMBINANTE PROCEDENTE DE LA HEVEA BRASILIENSIS, AISLANDOSE DE LA MEZCLA DE REACCION LA (S)CIANOHIDRINA RESULTANTE.
ES97927041T 1997-01-13 1997-05-26 Procedimientos enzimaticos para la obtencion de (s)-cianhidrinas. Expired - Lifetime ES2161466T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0004197A AT406959B (de) 1997-01-13 1997-01-13 Enantioselektives verfahren zur herstellung von (s)-cyanhydrinen

Publications (1)

Publication Number Publication Date
ES2161466T3 true ES2161466T3 (es) 2001-12-01

Family

ID=3479966

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97927041T Expired - Lifetime ES2161466T3 (es) 1997-01-13 1997-05-26 Procedimientos enzimaticos para la obtencion de (s)-cianhidrinas.

Country Status (10)

Country Link
US (1) US6337196B1 (es)
EP (1) EP0951561B1 (es)
JP (1) JP2001513625A (es)
AT (2) AT406959B (es)
AU (1) AU3167497A (es)
CA (1) CA2277916C (es)
DE (1) DE59704263D1 (es)
DK (1) DK0951561T3 (es)
ES (1) ES2161466T3 (es)
WO (1) WO1998030711A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078225B2 (en) * 2000-06-02 2006-07-18 Nippon Shokubai Co., Ltd. Method for enzymatically producing an optically active cyanohydrin
ATE318914T1 (de) 2001-01-16 2006-03-15 Dsm Fine Chem Austria Gmbh Gene, enthaltend eine für hydroxynitrillyase codierende dna-sequenz, rekombinante proteine mit hydroxynitrillyase-aktivität und deren verwendung
AT411064B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von enantiomerenangereicherten cyanhydrinen unter verwendung von acetalen oder ketalen als substrate
AT411065B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von heterocyclischen (r)- und (s)-cyanhydrinen
AT410792B (de) * 2001-12-28 2003-07-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von geschützten, enantiomeren-angereicherten cyanhydrinen durch in-situ-derivatisierung
CN101103113A (zh) * 2005-01-20 2008-01-09 Dsm精细化学奥地利Nfg两合公司 具有改善的底物接受性的r-羟腈裂解酶及其用途
JP4729408B2 (ja) * 2006-02-01 2011-07-20 株式会社日本触媒 固定化酵素の製造方法
DE102006058373A1 (de) 2006-12-08 2008-06-12 Evocatal Gmbh (R)-Hydroxynitril-Lyase aus Brassicaceen
EP2092060B1 (en) 2006-12-14 2014-01-22 DSM IP Assets B.V. R-hnl random variants and their use for preparing optically pure, sterically hindered cyanohydrins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine
AT400035B (de) * 1993-06-01 1995-09-25 Chemie Linz Gmbh Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine
DK0799894T3 (da) 1996-02-09 2004-08-09 Degussa Fremgangsmåde til fremstilling af (S)-cyanhydriner

Also Published As

Publication number Publication date
JP2001513625A (ja) 2001-09-04
ATE204023T1 (de) 2001-08-15
CA2277916A1 (en) 1998-07-16
ATA4197A (de) 2000-03-15
WO1998030711A1 (de) 1998-07-16
DK0951561T3 (da) 2001-10-08
AT406959B (de) 2000-11-27
EP0951561B1 (de) 2001-08-08
US6337196B1 (en) 2002-01-08
CA2277916C (en) 2006-11-14
EP0951561A1 (de) 1999-10-27
DE59704263D1 (de) 2001-09-13
AU3167497A (en) 1998-08-03

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