ES2165840T3 - Vacunas para la hepatitis a. - Google Patents

Vacunas para la hepatitis a.

Info

Publication number
ES2165840T3
ES2165840T3 ES91903208T ES91903208T ES2165840T3 ES 2165840 T3 ES2165840 T3 ES 2165840T3 ES 91903208 T ES91903208 T ES 91903208T ES 91903208 T ES91903208 T ES 91903208T ES 2165840 T3 ES2165840 T3 ES 2165840T3
Authority
ES
Spain
Prior art keywords
virus
hepatitis
incorporated
dna
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91903208T
Other languages
English (en)
Inventor
Howard Christopher Thomas
Peter Karayiannis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial College of London
Original Assignee
Imperial College of London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial College of London filed Critical Imperial College of London
Application granted granted Critical
Publication of ES2165840T3 publication Critical patent/ES2165840T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Valve Device For Special Equipments (AREA)
  • Valve-Gear Or Valve Arrangements (AREA)
  • Glass Compositions (AREA)

Abstract

UN POLIPEPTIDO AISLADO QUE COMPRENDE UNA IMPORTANTE PARTE ANTIGENICA DE AL MENOS UN EPITOPO DEL VIRUS HEPATITIS A, ESTANDO EL POLIPEPTIDO LIBRE DE MATERIAL INFECCIOSO. EL POLIPEPTIDO ES EL PRODUCTO EXPRIMIDO DE UN MOLECULA DNA QUE HA SIDO INCORPORADA A UN VIRUS, PREFERENTEMENTE VIRUS DE VACUNA, UTILIZANDO TECNOLOGIA DNA DE RECOMBINACION. ESTE PRODUCTO, DEL VIRUS RECOMBINANTE QUE CONTIENE EL CODIGO MOLECULAR DNA PARA EL, PUEDE INCORPORARSE A UNA VACUNA PARA INMUNIZAR CONTRA EL VIRUS DE HEPATITIS A.
ES91903208T 1990-02-02 1991-02-04 Vacunas para la hepatitis a. Expired - Lifetime ES2165840T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909002387A GB9002387D0 (en) 1990-02-02 1990-02-02 Improvements relating to the prevention of hepatitis

Publications (1)

Publication Number Publication Date
ES2165840T3 true ES2165840T3 (es) 2002-04-01

Family

ID=10670339

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91903208T Expired - Lifetime ES2165840T3 (es) 1990-02-02 1991-02-04 Vacunas para la hepatitis a.

Country Status (9)

Country Link
US (1) US5605692A (es)
EP (1) EP0513090B1 (es)
JP (1) JP3086250B2 (es)
AT (1) ATE205220T1 (es)
CA (1) CA2072982C (es)
DE (1) DE69132717T2 (es)
ES (1) ES2165840T3 (es)
GB (1) GB9002387D0 (es)
WO (1) WO1991011460A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU735733B2 (en) * 1996-04-19 2001-07-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Antigenically reactive regions of the hepatitis A virus polyprotein
US6368602B1 (en) * 2000-06-16 2002-04-09 Hadasit Medical Research Services And Development Ltd Mucosal immunization against hepatitis A virus (HAV) through rectal administration of HAV vaccine
US8357525B2 (en) 2007-09-04 2013-01-22 The United States of America, as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention Thermal inactivation of rotavirus
CN103923882B (zh) * 2013-08-09 2016-09-28 北京科兴生物制品有限公司 甲肝病毒单克隆抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614793A (en) * 1983-10-14 1986-09-30 Merck & Co., Inc. Hepatitis A--subunit antigen
EP0154587B1 (en) * 1984-03-02 1991-05-15 Merck & Co. Inc. Fragments of dna which encode peptides capable of inducing in vivo the synthesis of anti-hepatitis a virus antibodies
SU1469856A1 (ru) * 1986-07-31 1990-09-30 Институт биоорганической химии им.М.М.Шемякина Способ конструировани рекомбинантной плазмидной ДНК, кодирующей синтез полипептидных субстанций против гепатита А

Also Published As

Publication number Publication date
EP0513090B1 (en) 2001-09-05
CA2072982C (en) 1999-09-07
EP0513090A1 (en) 1992-11-19
US5605692A (en) 1997-02-25
DE69132717T2 (de) 2002-07-04
CA2072982A1 (en) 1991-08-03
WO1991011460A1 (en) 1991-08-08
DE69132717D1 (en) 2001-10-11
ATE205220T1 (de) 2001-09-15
GB9002387D0 (en) 1990-04-04
JPH05503524A (ja) 1993-06-10
JP3086250B2 (ja) 2000-09-11

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