ES2168520T3 - Compuestos y metodo para la deteccion y prevencion de infeccion por t. cruzi. - Google Patents
Compuestos y metodo para la deteccion y prevencion de infeccion por t. cruzi.Info
- Publication number
- ES2168520T3 ES2168520T3 ES96941416T ES96941416T ES2168520T3 ES 2168520 T3 ES2168520 T3 ES 2168520T3 ES 96941416 T ES96941416 T ES 96941416T ES 96941416 T ES96941416 T ES 96941416T ES 2168520 T3 ES2168520 T3 ES 2168520T3
- Authority
- ES
- Spain
- Prior art keywords
- cruzi
- compounds
- detection
- infection
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 208000015181 infectious disease Diseases 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 1
- 208000024699 Chagas disease Diseases 0.000 abstract 1
- 241000223104 Trypanosoma Species 0.000 abstract 1
- 241000223109 Trypanosoma cruzi Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
LA INVENCION SE REFIERE A COMPUESTOS Y METODOS PARA DIAGNOSTICAR INFECCIONES POR TRYPANOSOMA CRUZI. LOS COMPUESTOS REVELADOS SON POLIPEPTIDOS O SUS ANTICUERPOS, QUE CONTIENEN UNO O MAS EPITOPES DE ANTIGENOS DE T. CRUZI. LOS COMPUESTOS SON UTILES EN VARIOS ENSAYOS INMUNOLOGICOS PARA LA DETECCION DE INFECCIONES POR T. CRUZI. LOS COMPUESTOS POLIPEPTIDOS SON ADEMAS UTILES EN VACUNAS Y FORMULAS FARMACEUTICAS PARA INDUCIR UNA INMUNIDAD PROTECTORA FRENTE A LA ENFERMEDAD DE CHAGAS EN PERSONAS EXPUESTAS AL T. CRUZI.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/557,309 US5916572A (en) | 1995-11-14 | 1995-11-14 | Compounds and methods for the detection and prevention of T. cruzi infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2168520T3 true ES2168520T3 (es) | 2002-06-16 |
Family
ID=24224889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96941416T Expired - Lifetime ES2168520T3 (es) | 1995-11-14 | 1996-11-14 | Compuestos y metodo para la deteccion y prevencion de infeccion por t. cruzi. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5916572A (es) |
| EP (1) | EP0874992B1 (es) |
| JP (1) | JP2000503111A (es) |
| AR (1) | AR004567A1 (es) |
| AT (1) | ATE213544T1 (es) |
| AU (1) | AU722152B2 (es) |
| BR (1) | BRPI9611455B8 (es) |
| CA (1) | CA2237299A1 (es) |
| DE (1) | DE69619405T2 (es) |
| DK (1) | DK0874992T3 (es) |
| ES (1) | ES2168520T3 (es) |
| MX (1) | MX9803841A (es) |
| PT (1) | PT874992E (es) |
| WO (1) | WO1997018475A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403103B1 (en) * | 1994-08-12 | 2002-06-11 | Bio Merieux | Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease |
| US6419933B1 (en) * | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
| US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
| WO1999005528A1 (en) * | 1997-07-28 | 1999-02-04 | Immunetics | Assay and device for identifying trypanosoma cruzi infection |
| US6908898B1 (en) * | 1998-06-15 | 2005-06-21 | Lars Holmgren | Angiogenesis related molecules |
| EP0976763B1 (en) * | 1998-07-30 | 2003-11-05 | Innogenetics N.V. | Antigens and immunoassays for diagnosing Chagas' disease |
| FR2788527A1 (fr) | 1999-01-15 | 2000-07-21 | Bio Merieux | Pseudopeptide, procede de synthese, reactif et applications |
| PE20050942A1 (es) * | 2003-12-04 | 2005-11-10 | Louis V Kirchhoff | Polipeptidos recombinantes para diagnosticar la infeccion con el trypanosoma cruzi |
| US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
| ES2490193T3 (es) * | 2008-07-04 | 2014-09-03 | Institut De Recherche Pour Le Développement (Ird) | Procedimiento para el cribado de proteínas segregadas conservadas |
| FR2945290A1 (fr) * | 2009-05-07 | 2010-11-12 | Maan Zrein | Anticorps biomarqueur et dispositif de diagnostic pour la detection de certaines maladies auto-immunes |
| FR2958753B1 (fr) * | 2010-04-13 | 2018-03-16 | Institut De Recherche Pour Le Developpement (Ird) | Construction antigenique et ses applications pour le depistage de trypanosomoses chez l'homme et l'animal |
| US20240133884A1 (en) * | 2022-07-21 | 2024-04-25 | University Of Georgia Research Foundation, Inc. | Compositions and methods for detecting trypanosoma cruzi infection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4870006A (en) * | 1986-07-24 | 1989-09-26 | Codon | Antigenic material for a chagas' disease detection system |
| WO1990002564A1 (en) * | 1988-09-12 | 1990-03-22 | Codon | Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi |
| BR9006039A (pt) * | 1990-11-28 | 1992-07-14 | Fundacao Oswaldo Cruz | Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos |
| US5304371A (en) * | 1992-02-14 | 1994-04-19 | Lasys Corporation | Peptide for diagnosing and immunizing against T. cruzi infection |
| TW246717B (es) * | 1992-07-10 | 1995-05-01 | Abbott Lab | |
| US5756662A (en) * | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
-
1995
- 1995-11-14 US US08/557,309 patent/US5916572A/en not_active Expired - Lifetime
-
1996
- 1996-11-12 AR ARP960105145A patent/AR004567A1/es active IP Right Grant
- 1996-11-14 ES ES96941416T patent/ES2168520T3/es not_active Expired - Lifetime
- 1996-11-14 AU AU10568/97A patent/AU722152B2/en not_active Ceased
- 1996-11-14 BR BRPI9611455-0B8A patent/BRPI9611455B8/pt not_active IP Right Cessation
- 1996-11-14 AT AT96941416T patent/ATE213544T1/de not_active IP Right Cessation
- 1996-11-14 EP EP96941416A patent/EP0874992B1/en not_active Expired - Lifetime
- 1996-11-14 DK DK96941416T patent/DK0874992T3/da active
- 1996-11-14 WO PCT/US1996/018624 patent/WO1997018475A1/en not_active Ceased
- 1996-11-14 CA CA002237299A patent/CA2237299A1/en not_active Abandoned
- 1996-11-14 JP JP9519161A patent/JP2000503111A/ja active Pending
- 1996-11-14 PT PT96941416T patent/PT874992E/pt unknown
- 1996-11-14 DE DE69619405T patent/DE69619405T2/de not_active Expired - Fee Related
-
1998
- 1998-05-14 MX MX9803841A patent/MX9803841A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR004567A1 (es) | 1998-12-16 |
| ATE213544T1 (de) | 2002-03-15 |
| DE69619405T2 (de) | 2002-10-17 |
| PT874992E (pt) | 2002-08-30 |
| US5916572A (en) | 1999-06-29 |
| EP0874992B1 (en) | 2002-02-20 |
| AU722152B2 (en) | 2000-07-20 |
| BR9611455A (pt) | 2001-01-02 |
| DE69619405D1 (de) | 2002-03-28 |
| MX9803841A (es) | 1998-09-30 |
| BRPI9611455B8 (pt) | 2014-07-01 |
| DK0874992T3 (da) | 2002-03-25 |
| AU1056897A (en) | 1997-06-05 |
| JP2000503111A (ja) | 2000-03-14 |
| BRPI9611455B1 (pt) | 2008-11-04 |
| WO1997018475A1 (en) | 1997-05-22 |
| EP0874992A1 (en) | 1998-11-04 |
| CA2237299A1 (en) | 1997-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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