BR9611455A - Compostos e métodos para a detecção e prevenção de infecção por t. cruzi. - Google Patents

Compostos e métodos para a detecção e prevenção de infecção por t. cruzi.

Info

Publication number
BR9611455A
BR9611455A BR9611455-0A BR9611455A BR9611455A BR 9611455 A BR9611455 A BR 9611455A BR 9611455 A BR9611455 A BR 9611455A BR 9611455 A BR9611455 A BR 9611455A
Authority
BR
Brazil
Prior art keywords
compounds
methods
infection
cruzi
prevention
Prior art date
Application number
BR9611455-0A
Other languages
English (en)
Other versions
BRPI9611455B8 (pt
BRPI9611455B1 (pt
Inventor
Steven G Reed
Yasir A W Skeiky
Michael J Lodes
Raymond L Houghton
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24224889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9611455(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of BR9611455A publication Critical patent/BR9611455A/pt
Publication of BRPI9611455B1 publication Critical patent/BRPI9611455B1/pt
Publication of BRPI9611455B8 publication Critical patent/BRPI9611455B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"COMPOSTOS E MéTODOS PARA A DETECçãO E PREVENçãO DE INFECçãO POR T. CRUZI" A presente invenção refere-se a compostos e métodos para diagnosticar infecção por Trypanosoma cruzi. Os compostos descritos são polipeptídios ou anti-corpos para os mesmos, que contêm um ou mais epítopos de antígenos de T. cruzi. Os compostos são úteis em uma variedade de imunoensaios para detectar infecção por T. cruzi. Os compostos de polipeptídios são ainda úteis em vacinas e em composições farmacêuticas para induzir a imunidade protetora contra o mal de Chagas em indivíduos expostos a T. cruzi.
BRPI9611455-0B8A 1995-11-14 1996-11-14 Método para detectar infecção por t. cruzi em uma amostra biológica; vetor de expressão recombinante; célula hospedeira; kit de diagnóstico; composição farmacêutica; vacina para estimular a produção de anticorpos; e combinação de polipeptídeos. BRPI9611455B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/557,309 US5916572A (en) 1995-11-14 1995-11-14 Compounds and methods for the detection and prevention of T. cruzi infection
PCT/US1996/018624 WO1997018475A1 (en) 1995-11-14 1996-11-14 Compounds and methods for the detection and prevention of t. cruzi infection

Publications (3)

Publication Number Publication Date
BR9611455A true BR9611455A (pt) 2001-01-02
BRPI9611455B1 BRPI9611455B1 (pt) 2008-11-04
BRPI9611455B8 BRPI9611455B8 (pt) 2014-07-01

Family

ID=24224889

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9611455-0B8A BRPI9611455B8 (pt) 1995-11-14 1996-11-14 Método para detectar infecção por t. cruzi em uma amostra biológica; vetor de expressão recombinante; célula hospedeira; kit de diagnóstico; composição farmacêutica; vacina para estimular a produção de anticorpos; e combinação de polipeptídeos.

Country Status (14)

Country Link
US (1) US5916572A (pt)
EP (1) EP0874992B1 (pt)
JP (1) JP2000503111A (pt)
AR (1) AR004567A1 (pt)
AT (1) ATE213544T1 (pt)
AU (1) AU722152B2 (pt)
BR (1) BRPI9611455B8 (pt)
CA (1) CA2237299A1 (pt)
DE (1) DE69619405T2 (pt)
DK (1) DK0874992T3 (pt)
ES (1) ES2168520T3 (pt)
MX (1) MX9803841A (pt)
PT (1) PT874992E (pt)
WO (1) WO1997018475A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403103B1 (en) * 1994-08-12 2002-06-11 Bio Merieux Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease
US6228372B1 (en) * 1997-04-15 2001-05-08 Corixa Corporation Compounds and methods for the detection and prevention of T. cruzi infection
US6419933B1 (en) 1995-11-14 2002-07-16 Corixa Corporation Compounds and methods for the detection and prevention of T.cruzi infection
AU8604298A (en) * 1997-07-28 1999-02-16 Immunetics, Inc. Assay and device for identifying (trypanosoma cruzi) infection
US6908898B1 (en) * 1998-06-15 2005-06-21 Lars Holmgren Angiogenesis related molecules
EP0976763B1 (en) * 1998-07-30 2003-11-05 Innogenetics N.V. Antigens and immunoassays for diagnosing Chagas' disease
FR2788527A1 (fr) 1999-01-15 2000-07-21 Bio Merieux Pseudopeptide, procede de synthese, reactif et applications
PE20050942A1 (es) * 2003-12-04 2005-11-10 Louis V Kirchhoff Polipeptidos recombinantes para diagnosticar la infeccion con el trypanosoma cruzi
US7749717B2 (en) * 2006-10-19 2010-07-06 Abbott Laboratories Methods for the detection and diagnosis of Trypanosoma cruzi infection
ES2490193T3 (es) * 2008-07-04 2014-09-03 Institut De Recherche Pour Le Développement (Ird) Procedimiento para el cribado de proteínas segregadas conservadas
FR2945290A1 (fr) * 2009-05-07 2010-11-12 Maan Zrein Anticorps biomarqueur et dispositif de diagnostic pour la detection de certaines maladies auto-immunes
FR2958753B1 (fr) * 2010-04-13 2018-03-16 Institut De Recherche Pour Le Developpement (Ird) Construction antigenique et ses applications pour le depistage de trypanosomoses chez l'homme et l'animal
US20240133884A1 (en) * 2022-07-21 2024-04-25 University Of Georgia Research Foundation, Inc. Compositions and methods for detecting trypanosoma cruzi infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870006A (en) * 1986-07-24 1989-09-26 Codon Antigenic material for a chagas' disease detection system
WO1990002564A1 (en) * 1988-09-12 1990-03-22 Codon Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi
BR9006039A (pt) * 1990-11-28 1992-07-14 Fundacao Oswaldo Cruz Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos
US5304371A (en) * 1992-02-14 1994-04-19 Lasys Corporation Peptide for diagnosing and immunizing against T. cruzi infection
TW246717B (pt) * 1992-07-10 1995-05-01 Abbott Lab
US5756662A (en) * 1995-03-14 1998-05-26 Corixa Corporation Compounds and methods for the detection of T. cruzi infection

Also Published As

Publication number Publication date
PT874992E (pt) 2002-08-30
DE69619405T2 (de) 2002-10-17
DE69619405D1 (de) 2002-03-28
BRPI9611455B8 (pt) 2014-07-01
BRPI9611455B1 (pt) 2008-11-04
JP2000503111A (ja) 2000-03-14
MX9803841A (es) 1998-09-30
ES2168520T3 (es) 2002-06-16
AU1056897A (en) 1997-06-05
ATE213544T1 (de) 2002-03-15
CA2237299A1 (en) 1997-05-22
EP0874992A1 (en) 1998-11-04
AU722152B2 (en) 2000-07-20
EP0874992B1 (en) 2002-02-20
US5916572A (en) 1999-06-29
AR004567A1 (es) 1998-12-16
DK0874992T3 (da) 2002-03-25
WO1997018475A1 (en) 1997-05-22

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