ES2169043T3 - Peptidos del papilomavirus humano aplicable en las composiciones para inducir una reaccion de los linfocitos t en el hombre. - Google Patents
Peptidos del papilomavirus humano aplicable en las composiciones para inducir una reaccion de los linfocitos t en el hombre.Info
- Publication number
- ES2169043T3 ES2169043T3 ES93913618T ES93913618T ES2169043T3 ES 2169043 T3 ES2169043 T3 ES 2169043T3 ES 93913618 T ES93913618 T ES 93913618T ES 93913618 T ES93913618 T ES 93913618T ES 2169043 T3 ES2169043 T3 ES 2169043T3
- Authority
- ES
- Spain
- Prior art keywords
- lymphocytes
- peptides
- man
- induce
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- -1 AMINO SEQUENCE Chemical group 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 208000019065 cervical carcinoma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UN PEPTIDO COMPRENDE UNA SECUENCIA AMINO ACIDA DERIVADA DE LA PROTEINA DEL VIRUS DE PAPILOMA HUMANO (HPV) DONDE TAL SECUENCIA TIENE LA HABILIDAD DE ENLAZAR UNA MOLECULA DE CLASE I DE MAYOR HISTOCOMPATIBILDAD COMPLEJA HUMANA. SE DESCRIBE SU USO EN TRATAMIENTOS PROFILACTICOS O TERAPEUTICOS DE CARCINOMA CERVICAL Y OTRAS ENFERMEDADES RELACIONADAS CON EL HPV.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92201252 | 1992-05-05 | ||
| EP92203870 | 1992-12-10 | ||
| EP93200243 | 1993-02-01 | ||
| EP93200621 | 1993-03-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2169043T3 true ES2169043T3 (es) | 2002-07-01 |
Family
ID=27442368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93913618T Expired - Lifetime ES2169043T3 (es) | 1992-05-05 | 1993-05-04 | Peptidos del papilomavirus humano aplicable en las composiciones para inducir una reaccion de los linfocitos t en el hombre. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7364741B1 (es) |
| EP (1) | EP0593754B1 (es) |
| JP (1) | JP3609405B2 (es) |
| AT (1) | ATE207495T1 (es) |
| AU (2) | AU675794B2 (es) |
| CA (1) | CA2112798A1 (es) |
| DE (1) | DE69330988T2 (es) |
| DK (1) | DK0593754T3 (es) |
| ES (1) | ES2169043T3 (es) |
| FI (1) | FI940054A0 (es) |
| IL (1) | IL105554A (es) |
| NO (1) | NO940043D0 (es) |
| NZ (1) | NZ253330A (es) |
| PT (1) | PT593754E (es) |
| WO (1) | WO1993022338A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6419931B1 (en) * | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| US7252829B1 (en) | 1998-06-17 | 2007-08-07 | Idm Pharma, Inc. | HLA binding peptides and their uses |
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| AU4998993A (en) * | 1992-08-07 | 1994-03-03 | Epimmune, Inc. | Hla binding peptides and their uses |
| CN1118572A (zh) * | 1993-03-05 | 1996-03-13 | 萨依特尔有限公司 | Hla-a2.1组合肽及其用途 |
| US5480970A (en) * | 1993-12-22 | 1996-01-02 | Resolution Pharmaceuticals | Metal chelators |
| GB9717953D0 (en) * | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
| US6183746B1 (en) | 1997-10-09 | 2001-02-06 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
| US20040002117A1 (en) | 1998-02-12 | 2004-01-01 | Hogan Patrick G. | Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases |
| WO1999040930A1 (en) | 1998-02-12 | 1999-08-19 | Center For Blood Research, Inc. | Specific inhibitors of nfat activation by calcineurin and their use in treating immune-related diseases |
| DE19925199A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| DE19925235A1 (de) | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| FR2794370B1 (fr) | 1999-06-03 | 2003-10-17 | Biovector Therapeutics | Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination |
| EP2100620A1 (en) * | 1999-09-16 | 2009-09-16 | Eisai Corporation of North America | Nucleic acids encoding polyepitope polypeptides |
| FR2794371B1 (fr) * | 1999-10-07 | 2004-06-18 | Biovector Therapeutics | Fragments proteiquespolyepitopiques, leur obtention et leurs utilisations notamment en vaccination |
| US7026443B1 (en) * | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
| WO2002077012A2 (en) | 2001-03-23 | 2002-10-03 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Human papilloma virus immunoreative peptides |
| US7666391B2 (en) | 2001-06-01 | 2010-02-23 | Burnham Institute For Medical Research | Breast homing peptides and methods of identifying same using aminopeptidase P |
| WO2002099379A2 (en) * | 2001-06-01 | 2002-12-12 | The Burnham Institute | Breast homing peptides and methods of identifying same using aminopeptidase p |
| JP2008044848A (ja) * | 2004-11-30 | 2008-02-28 | Univ Kurume | Hla−a24拘束性腫瘍抗原ペプチド |
| US8252893B2 (en) * | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| US8926961B2 (en) * | 2007-10-03 | 2015-01-06 | Board Of Trustees Of The University Of Arkansas | HPV E6 protein T cell epitopes and uses thereof |
| US8652482B2 (en) * | 2007-10-03 | 2014-02-18 | The Board Of Trustees Of The University Of Arkansas | HPV E6 protein T cell epitopes and uses thereof |
| CA2721366C (en) | 2008-04-17 | 2017-06-06 | Elizabeth Ann Vasievich | Stimulation of an immune response by enantiomers of cationic lipids |
| EP2391635B1 (en) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
| CN102153656B (zh) * | 2011-01-12 | 2014-11-19 | 广州市元通医药科技有限公司 | 一种嵌合病毒样颗粒疫苗及其制备方法 |
| CN105163753B (zh) | 2012-06-15 | 2018-12-21 | Pds生物科技公司 | 阳离子脂质疫苗组合物和使用方法 |
| CN105101991A (zh) | 2012-09-21 | 2015-11-25 | Pds生物科技公司 | 改进的疫苗组合物和使用方法 |
| WO2017083820A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| EP3377099A4 (en) | 2015-11-18 | 2019-07-24 | ImmunoVaccine Technologies Inc. | ADJUVANT SYSTEMS AND WATER-FREE VAPOR COMPOSITION OF ONE POLYI: C-POLYNUCLEOTIDADJUVANS AND ADJUVANS ON LIPID BASE |
| US12303561B2 (en) * | 2017-04-03 | 2025-05-20 | Biontech Us Inc. | Protein antigens and uses thereof |
| WO2018187515A1 (en) | 2017-04-04 | 2018-10-11 | Avidea Technologies, Inc. | Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response |
| CA3084957A1 (en) | 2017-12-05 | 2019-06-13 | Pds Biotechnology Corporation | Methods and compositions comprising cationic lipids for stimulating type 1 interferon genes |
| WO2020132136A1 (en) * | 2018-12-19 | 2020-06-25 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4777239A (en) * | 1986-07-10 | 1988-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic peptides of human papilloma virus |
| FR2641081A1 (es) | 1988-12-23 | 1990-06-29 | Medgenix Group | |
| DE3907721A1 (de) * | 1989-03-10 | 1990-09-20 | Behringwerke Ag | Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16 |
| DE4015044A1 (de) * | 1990-05-10 | 1991-11-14 | Behringwerke Ag | Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18 |
| US5932412A (en) * | 1990-05-11 | 1999-08-03 | Euro-Diagnostica Ab | Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes |
| CN1067382A (zh) | 1990-09-26 | 1992-12-30 | 布里斯托尔-迈尔斯斯奎尔公司 | 人类乳头状瘤病毒肽的表达以及在致免疫组合物中的应用 |
| US6183745B1 (en) * | 1990-12-12 | 2001-02-06 | The University Of Queensland | Subunit papilloma virus vaccine and peptides for use therein |
| US6419931B1 (en) * | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| US6037135A (en) * | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| US5662907A (en) * | 1992-08-07 | 1997-09-02 | Cytel Corporation | Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes |
| US5679509A (en) * | 1993-09-28 | 1997-10-21 | University Of New Mexico | Methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer |
| US5550214A (en) * | 1994-02-10 | 1996-08-27 | Brigham And Women's Hospital | Isolated antigenic oncogene peptide fragments and uses |
| US5686068A (en) * | 1994-03-24 | 1997-11-11 | Ludwig Institute For Cancer Research | Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof |
| US5554724A (en) * | 1994-03-24 | 1996-09-10 | University Of Leiden | Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof |
| US6218363B1 (en) * | 1996-08-28 | 2001-04-17 | Thomas Jefferson University | MHC peptides and methods of use |
| US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
| US6183746B1 (en) * | 1997-10-09 | 2001-02-06 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
| US6242176B1 (en) * | 1998-07-13 | 2001-06-05 | Loyola University Of Chicago | Papillomavirus cellular receptor |
| US6548299B1 (en) * | 1999-11-12 | 2003-04-15 | Mark J. Pykett | Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices |
| WO2000039188A1 (en) * | 1998-12-25 | 2000-07-06 | Mitsubishi Rayon Co., Ltd. | Epoxy resin composition, prepreg, and roll made of resin reinforced with reinforcing fibers |
| DE19925199A1 (de) * | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| FR2794370B1 (fr) * | 1999-06-03 | 2003-10-17 | Biovector Therapeutics | Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| US7026443B1 (en) * | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
| FR2806727A1 (fr) * | 2000-03-23 | 2001-09-28 | Pf Medicament | Molecule d'interet pharmaceutique comprotant en son extremite n-terminale un acide glutamique ou une glutamine sous forme de sel d'addition d'acide fort physiologiquement acceptable |
| US20030215425A1 (en) * | 2001-12-07 | 2003-11-20 | Simard John J. L. | Epitope synchronization in antigen presenting cells |
| US6861234B1 (en) * | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
| DK1296711T3 (da) * | 2000-06-26 | 2006-08-28 | Stressgen Biotechnologies Corp | HPV-E7 til behandling af humant papillomavirus |
| DE10059631A1 (de) * | 2000-12-01 | 2002-07-18 | Medigene Ag | T-Zellepitope des Papillomavirus L1-und E7-Proteins und ihre Verwendung in Diagnostik und Therapie |
| WO2002077012A2 (en) * | 2001-03-23 | 2002-10-03 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Human papilloma virus immunoreative peptides |
| EP1250005A1 (en) * | 2001-04-12 | 2002-10-16 | BRITISH TELECOMMUNICATIONS public limited company | Video communication with feedback of the caller's position relative to the camera |
| FR2824326B1 (fr) * | 2001-05-04 | 2004-03-19 | Commissariat Energie Atomique | Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications |
| EP1417353A4 (en) * | 2001-07-20 | 2005-08-03 | Univ Texas | METHODS AND COMPOSITIONS ASSOCIATED WITH HPV ASSOCIATED PENCILS AND CANNULAR WELLS, INCLUDING CIN |
| US20040171081A1 (en) * | 2001-11-23 | 2004-09-02 | Abraham Mittelman | Antigens |
| CA2500715A1 (en) * | 2002-10-03 | 2004-04-15 | Epimmune Inc. | Hla binding peptides and their uses |
| CA2511775A1 (en) * | 2002-12-10 | 2004-06-24 | Epimmune Inc. | Hla-a1,-a2 -a3,-a24,-b7,and -b44 tumor associated antigen peptides and compositions |
| JP4647606B2 (ja) * | 2003-09-05 | 2011-03-09 | ジェネンコー・インターナショナル・インク | Hpvcd8+t細胞エピトープ |
| JP5030594B2 (ja) * | 2003-12-23 | 2012-09-19 | アルボー ビータ コーポレーション | Hpvの発癌性株に対する抗体およびそれらの使用方法 |
-
1993
- 1993-04-29 IL IL10555493A patent/IL105554A/en not_active IP Right Cessation
- 1993-05-04 WO PCT/NL1993/000093 patent/WO1993022338A1/en not_active Ceased
- 1993-05-04 CA CA002112798A patent/CA2112798A1/en not_active Abandoned
- 1993-05-04 EP EP93913618A patent/EP0593754B1/en not_active Expired - Lifetime
- 1993-05-04 JP JP51914593A patent/JP3609405B2/ja not_active Expired - Fee Related
- 1993-05-04 PT PT93913618T patent/PT593754E/pt unknown
- 1993-05-04 ES ES93913618T patent/ES2169043T3/es not_active Expired - Lifetime
- 1993-05-04 NZ NZ253330A patent/NZ253330A/en not_active IP Right Cessation
- 1993-05-04 DE DE69330988T patent/DE69330988T2/de not_active Expired - Lifetime
- 1993-05-04 DK DK93913618T patent/DK0593754T3/da active
- 1993-05-04 AT AT93913618T patent/ATE207495T1/de not_active IP Right Cessation
- 1993-05-04 AU AU43586/93A patent/AU675794B2/en not_active Ceased
- 1993-05-04 US US08/170,344 patent/US7364741B1/en not_active Expired - Fee Related
-
1994
- 1994-01-05 NO NO940043A patent/NO940043D0/no unknown
- 1994-01-05 FI FI940054A patent/FI940054A0/fi not_active Application Discontinuation
-
1996
- 1996-11-25 AU AU71970/96A patent/AU7197096A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2112798A1 (en) | 1993-11-11 |
| PT593754E (pt) | 2002-04-29 |
| DE69330988D1 (de) | 2001-11-29 |
| IL105554A (en) | 1999-08-17 |
| NZ253330A (en) | 1996-06-25 |
| AU675794B2 (en) | 1997-02-20 |
| FI940054A0 (fi) | 1994-01-05 |
| JPH07503975A (ja) | 1995-04-27 |
| NO940043D0 (no) | 1994-01-05 |
| EP0593754A1 (en) | 1994-04-27 |
| JP3609405B2 (ja) | 2005-01-12 |
| WO1993022338A1 (en) | 1993-11-11 |
| DK0593754T3 (da) | 2002-02-18 |
| AU7197096A (en) | 1997-02-06 |
| AU4358693A (en) | 1993-11-29 |
| ATE207495T1 (de) | 2001-11-15 |
| US7364741B1 (en) | 2008-04-29 |
| EP0593754B1 (en) | 2001-10-24 |
| DE69330988T2 (de) | 2002-06-20 |
| IL105554A0 (en) | 1993-08-18 |
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