ES2169258T3 - Utilizacion de proteasa de subtilisina mutada en productos cosmeticos. - Google Patents
Utilizacion de proteasa de subtilisina mutada en productos cosmeticos.Info
- Publication number
- ES2169258T3 ES2169258T3 ES96929256T ES96929256T ES2169258T3 ES 2169258 T3 ES2169258 T3 ES 2169258T3 ES 96929256 T ES96929256 T ES 96929256T ES 96929256 T ES96929256 T ES 96929256T ES 2169258 T3 ES2169258 T3 ES 2169258T3
- Authority
- ES
- Spain
- Prior art keywords
- subtilisine
- muted
- protease
- cosmetic products
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REIVINDICA EL USO EN PRODUCTOS COSMETICOS DE UNA PROTEASA MUTADA DEL TIPO SUBTILISINA QUE LLEVA AL MENOS UNA MUTACION EN SU SECUENCIA DE AMINOACIDOS, QUE HACE QUE LA CARGA POSITIVA DISMINUYA O LA CARGA NEGATIVA AUMENTE EN LA REGION DE UNION AL SUBSTRATO DE LA MOLECULA. LAS PROTEASAS DE ESTE TIPO MUESTRAN UN POTENCIAL DE IRRITACION SORPRENDENTEMENTE PEQUEÑO PARA LA PIEL Y LAS MUCOSAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19530816A DE19530816A1 (de) | 1995-08-23 | 1995-08-23 | Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2169258T3 true ES2169258T3 (es) | 2002-07-01 |
Family
ID=7770073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96929256T Expired - Lifetime ES2169258T3 (es) | 1995-08-23 | 1996-08-14 | Utilizacion de proteasa de subtilisina mutada en productos cosmeticos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6509021B1 (es) |
| EP (1) | EP0845972B1 (es) |
| JP (1) | JPH11512092A (es) |
| AT (1) | ATE209888T1 (es) |
| DE (2) | DE19530816A1 (es) |
| DK (1) | DK0845972T3 (es) |
| ES (1) | ES2169258T3 (es) |
| WO (1) | WO1997007770A1 (es) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6368595B2 (en) * | 1998-01-08 | 2002-04-09 | Cosmoferm B.V. | Topical application of enzymes using a peelable film |
| US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
| BR9909130A (pt) | 1998-03-26 | 2000-12-19 | Procter & Gamble | Variantes de protease de serina tendo substituições de amino-ácido |
| US6495136B1 (en) | 1998-03-26 | 2002-12-17 | The Procter & Gamble Company | Proteases having modified amino acid sequences conjugated to addition moieties |
| DE19829789A1 (de) * | 1998-07-03 | 2000-01-05 | Beiersdorf Ag | Gegen Akne und entzündete Comedonen wirksame Zubereitungen enthaltend Serin-Proteasen und ein oder mehrere Calciumsalze |
| DE19857543A1 (de) * | 1998-12-14 | 2000-06-15 | Henkel Kgaa | Verwendung von Protease in flüssigen bis gelförmigen Wasch- und Reinigungsmitteln |
| KR20020021397A (ko) | 1999-07-22 | 2002-03-20 | 데이비드 엠 모이어 | 규정된 에피토프 영역에 아미노산 결실 및 치환을 갖는서브틸리신 프로테아제 변이체 |
| BR0012694A (pt) | 1999-07-22 | 2002-04-09 | Procter & Gamble | Conjugado de protease, composição de limpeza e composição de tratamento pessoal |
| CA2376045A1 (en) | 1999-07-22 | 2001-02-01 | The Procter & Gamble Company | Subtilisin protease variants having amino acid substitutions in defined epitope regions |
| US6946128B1 (en) | 1999-07-22 | 2005-09-20 | The Procter & Gamble Company | Protease conjugates having sterically protected epitope regions |
| DE10121463A1 (de) * | 2001-05-02 | 2003-02-27 | Henkel Kgaa | Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten |
| DE10153792A1 (de) | 2001-10-31 | 2003-05-22 | Henkel Kgaa | Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten |
| DE10162727A1 (de) | 2001-12-20 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii (DSM 14391) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease |
| DE10162728A1 (de) | 2001-12-20 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease |
| DE10163883A1 (de) * | 2001-12-22 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
| DE10163884A1 (de) | 2001-12-22 | 2003-07-10 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
| US6835385B2 (en) * | 2002-06-14 | 2004-12-28 | Carol J. Buck | Compositions and methods for softening, thinning and removing hyperkeratotic tissue |
| BRPI0416797A (pt) | 2003-11-19 | 2007-04-17 | Genencor Int | serina proteases, ácidos nucléicos codificando enzimas de serina e vetores e células hospedeiras incorporando as mesmas |
| US7985569B2 (en) | 2003-11-19 | 2011-07-26 | Danisco Us Inc. | Cellulomonas 69B4 serine protease variants |
| DE10360805A1 (de) * | 2003-12-23 | 2005-07-28 | Henkel Kgaa | Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease |
| DE102004019751A1 (de) * | 2004-04-23 | 2005-11-17 | Henkel Kgaa | Neue Alkalische Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Alkalischen Proteasen |
| KR100558751B1 (ko) | 2004-10-18 | 2006-03-14 | 주식회사 태평양 | 피부보습용 화장료 조성물 |
| FR2884711A1 (fr) * | 2005-04-26 | 2006-10-27 | Clarins Soc Par Actions Simpli | Composition cosmetique preparant la peau au rasage |
| FR2884710A1 (fr) * | 2005-04-26 | 2006-10-27 | Clarins Soc Par Actions Simpli | Composition cosmetique preparant la peau au rasage |
| PT2032698E (pt) | 2006-06-23 | 2012-09-24 | Danisco Us Inc | Avaliação sistemática de relações entre sequência e actividade utilizando bibliotecas de avaliação de locais em relação a múltiplas propriedades de engenharia |
| WO2008048537A1 (en) * | 2006-10-16 | 2008-04-24 | Danisco Us, Inc. Genencor Division | Non-phosphate dish detergents |
| DE102007003143A1 (de) | 2007-01-16 | 2008-07-17 | Henkel Kgaa | Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease |
| DE102007032111B4 (de) | 2007-07-09 | 2017-07-20 | Henkel Ag & Co. Kgaa | Neue Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen |
| DE102007036756A1 (de) | 2007-08-03 | 2009-02-05 | Henkel Ag & Co. Kgaa | Neue Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Proteasen |
| DE102007049830A1 (de) | 2007-10-16 | 2009-04-23 | Henkel Ag & Co. Kgaa | Neue Proteinvarianten durch zirkulare Permutation |
| DE102007051092A1 (de) | 2007-10-24 | 2009-04-30 | Henkel Ag & Co. Kgaa | Subtilisin aus Becillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin |
| US7618801B2 (en) | 2007-10-30 | 2009-11-17 | Danison US Inc. | Streptomyces protease |
| WO2009149144A2 (en) | 2008-06-06 | 2009-12-10 | Danisco Us Inc. | Compositions and methods comprising variant microbial proteases |
| US20100192985A1 (en) | 2008-11-11 | 2010-08-05 | Wolfgang Aehle | Compositions and methods comprising serine protease variants |
| EP2362896A2 (en) | 2008-11-11 | 2011-09-07 | Danisco US Inc. | Bacillus subtilisin comprising one or more combinable mutations |
| DE102009029513A1 (de) * | 2009-09-16 | 2011-03-24 | Henkel Ag & Co. Kgaa | Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Proteasen |
| EP2558573B1 (en) | 2010-04-15 | 2017-02-22 | Danisco US Inc. | Compositions and methods comprising variant proteases |
| PL3575389T3 (pl) | 2010-05-06 | 2025-06-02 | The Procter & Gamble Company | Produkty konsumenckie z odmianami proteaz |
| MX357386B (es) | 2011-05-05 | 2018-07-06 | Procter & Gamble | Composiciones y metodos que comprenden variantes de proteasa serina. |
| MX378782B (es) | 2011-05-05 | 2025-03-10 | Danisco Us Inc | Composiciones y metodos que comprenden variantes de proteasa serina. |
| DE102012201522A1 (de) * | 2012-02-02 | 2013-08-08 | Basf Se | Lagerstabiles flüssiges Geschirrspülmittel enthaltend Protease und Amylase |
| DE102013219467A1 (de) * | 2013-09-26 | 2015-03-26 | Henkel Ag & Co. Kgaa | Stabilisierte Inhibitor-Proteasevarianten |
| US10806769B2 (en) | 2016-03-31 | 2020-10-20 | Gojo Industries, Inc. | Antimicrobial peptide stimulating cleansing composition |
| EP3435765A1 (en) | 2016-03-31 | 2019-02-06 | Gojo Industries, Inc. | Antimicrobial peptide stimulating sanitizing composition |
| JP2019510036A (ja) | 2016-03-31 | 2019-04-11 | ゴジョ・インダストリーズ・インコーポレイテッド | プロバイオティクス/プレバイオティクス有効成分を含む清浄剤組成物 |
| US11564879B2 (en) | 2016-11-23 | 2023-01-31 | Gojo Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
| US11446235B2 (en) * | 2017-05-07 | 2022-09-20 | Locus Ip Company, Llc | Cosmetic compositions for skin health and methods of using same |
| US20250311734A1 (en) | 2022-05-14 | 2025-10-09 | Novozymes A/S | Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ208612A (en) | 1983-06-24 | 1991-09-25 | Genentech Inc | Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations |
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
| US5763257A (en) * | 1984-05-29 | 1998-06-09 | Genencor International, Inc. | Modified subtilisins having amino acid alterations |
| NZ221627A (en) | 1986-09-09 | 1993-04-28 | Genencor Inc | Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios |
| CN1056187C (zh) * | 1988-02-11 | 2000-09-06 | 金克克国际有限公司 | 新的蛋白水解酶及其在洗涤剂中的应用 |
| DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| ES2144990T3 (es) | 1989-08-25 | 2000-07-01 | Henkel Of America Inc | Enzima proteolitica alcalina y metodo de produccion. |
| US5230891A (en) * | 1990-08-20 | 1993-07-27 | Kanebo Limited | Modified protease, method of producing the same and cosmetic products containing the modified protease |
| DK0563169T3 (da) | 1990-12-21 | 1998-05-18 | Novo Nordisk As | Enzymmutanter med lille variation i molekylær ladning i et pH område |
| US5340735A (en) * | 1991-05-29 | 1994-08-23 | Cognis, Inc. | Bacillus lentus alkaline protease variants with increased stability |
| ATE148494T1 (de) | 1991-06-19 | 1997-02-15 | Exxon Chemical Patents Inc | Verfahren zu unterdrückung der nebelbildung von einzel verwendung schmieröl |
| AU682314B2 (en) * | 1992-07-17 | 1997-10-02 | Genencor International, Inc. | High alkaline serine proteases |
| DE69434962T2 (de) * | 1993-10-14 | 2008-01-17 | The Procter & Gamble Company, Cincinnati | Proteasehaltige reinigungsmittel |
| MA23346A1 (fr) * | 1993-10-14 | 1995-04-01 | Genencor Int | Variantes de la subtilisine |
| DK0701605T3 (da) | 1994-02-24 | 2008-07-28 | Henkel Ag & Co Kgaa | Forbedrede enzymer og detergenter indeholdende disse |
| ES2364774T3 (es) * | 1994-02-24 | 2011-09-14 | HENKEL AG & CO. KGAA | Enzimas mejoradas y detergentes que las contienen. |
| US5691295A (en) * | 1995-01-17 | 1997-11-25 | Cognis Gesellschaft Fuer Biotechnologie Mbh | Detergent compositions |
| US6599730B1 (en) * | 1994-05-02 | 2003-07-29 | Procter & Gamble Company | Subtilisin 309 variants having decreased adsorption and increased hydrolysis |
| FR2737119B1 (fr) * | 1995-07-25 | 1997-09-12 | Oreal | Composition siliconee contenant un actif sensible a l'eau |
| FR2737116B1 (fr) * | 1995-07-25 | 1997-08-22 | Oreal | Composition stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau |
-
1995
- 1995-08-23 DE DE19530816A patent/DE19530816A1/de not_active Withdrawn
-
1996
- 1996-08-14 US US09/011,889 patent/US6509021B1/en not_active Expired - Fee Related
- 1996-08-14 WO PCT/EP1996/003589 patent/WO1997007770A1/de not_active Ceased
- 1996-08-14 JP JP9509779A patent/JPH11512092A/ja active Pending
- 1996-08-14 EP EP96929256A patent/EP0845972B1/de not_active Revoked
- 1996-08-14 DK DK96929256T patent/DK0845972T3/da active
- 1996-08-14 ES ES96929256T patent/ES2169258T3/es not_active Expired - Lifetime
- 1996-08-14 AT AT96929256T patent/ATE209888T1/de not_active IP Right Cessation
- 1996-08-14 DE DE59608385T patent/DE59608385D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE59608385D1 (de) | 2002-01-17 |
| WO1997007770A1 (de) | 1997-03-06 |
| EP0845972B1 (de) | 2001-12-05 |
| US6509021B1 (en) | 2003-01-21 |
| DE19530816A1 (de) | 1997-02-27 |
| DK0845972T3 (da) | 2002-04-02 |
| JPH11512092A (ja) | 1999-10-19 |
| EP0845972A1 (de) | 1998-06-10 |
| ATE209888T1 (de) | 2001-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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