ES2169886T3 - Derivados condensados de la piperidina como inhibidor de sintesis de monoxido de nitrogeno. - Google Patents

Derivados condensados de la piperidina como inhibidor de sintesis de monoxido de nitrogeno.

Info

Publication number
ES2169886T3
ES2169886T3 ES98106569T ES98106569T ES2169886T3 ES 2169886 T3 ES2169886 T3 ES 2169886T3 ES 98106569 T ES98106569 T ES 98106569T ES 98106569 T ES98106569 T ES 98106569T ES 2169886 T3 ES2169886 T3 ES 2169886T3
Authority
ES
Spain
Prior art keywords
inhibitor
nitrogen monoxide
piperidine
same
condensed derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98106569T
Other languages
English (en)
Inventor
Naoyuki Taniguchi
Kaoru Kobayashi
Masao Naka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2169886T3 publication Critical patent/ES2169886T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPUESTO REPRESENTADO POR LA FORMULA (I): EN LA QUE TODOS LOS SIMBOLOS ESTAN DEFINIDOS EN LA ESPECIFICACION, O LA SAL ACIDA DE ADICION DEL MISMO O EL HIDRATO DEL MISMO; PROCESO DE PREPARACION DEL MISMO; Y UN INHIBIDOR DE LA SINTESIS DEL MONOXIDO DE NITROGENO QUE CONTENGA EL MISMO COMO PRINCIPIO ACTIVO.
ES98106569T 1997-04-10 1998-04-09 Derivados condensados de la piperidina como inhibidor de sintesis de monoxido de nitrogeno. Expired - Lifetime ES2169886T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9183097 1997-04-10
JP27319697 1997-10-07

Publications (1)

Publication Number Publication Date
ES2169886T3 true ES2169886T3 (es) 2002-07-16

Family

ID=26433266

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98106569T Expired - Lifetime ES2169886T3 (es) 1997-04-10 1998-04-09 Derivados condensados de la piperidina como inhibidor de sintesis de monoxido de nitrogeno.

Country Status (14)

Country Link
US (2) US6110930A (es)
EP (1) EP0870763B1 (es)
KR (1) KR19980081287A (es)
CN (1) CN1202486A (es)
AT (1) ATE210647T1 (es)
AU (1) AU746048B2 (es)
CA (1) CA2234571A1 (es)
DE (1) DE69802858T2 (es)
DK (1) DK0870763T3 (es)
ES (1) ES2169886T3 (es)
HU (1) HUP9800865A3 (es)
NO (1) NO310618B1 (es)
PT (1) PT870763E (es)
TW (1) TW427979B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2793248B1 (fr) * 1999-05-03 2001-06-29 Adir Nouveaux derives de 2,3-methano-aminoacides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU5246000A (en) * 1999-06-09 2000-12-28 Ono Pharmaceutical Co. Ltd. Analgesics
FR2794647A1 (fr) 1999-06-11 2000-12-15 Centre Nat Rech Scient Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
AU5566700A (en) * 1999-06-22 2001-01-09 Ono Pharmaceutical Co. Ltd. Process for the preparation of intermediate compounds of drugs
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2002121496A (ru) * 2000-02-10 2004-03-20 Оно Фармасьютикал Ко., Лтд. (Jp) Средство для лечения синдрома шегрена
AU2001296028A1 (en) * 2000-10-30 2002-05-15 Ono Pharmaceutical Co. Ltd. Remedies for extraocular inflammatory diseases
WO2003022309A1 (fr) * 2001-09-10 2003-03-20 Ono Pharmaceutical Co., Ltd. Remedes pour maladies allergiques
JP2006096665A (ja) * 2002-10-29 2006-04-13 Ono Pharmaceut Co Ltd 脊柱管狭窄症治療剤
WO2004101523A1 (en) * 2003-05-17 2004-11-25 Korea Research Institute Of Bioscience And Biotechnology Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
KR100594377B1 (ko) * 2003-05-17 2006-06-30 한국생명공학연구원 항염증 활성을 갖는 신규 2-옥소-피페리딘 유도체(ⅰ)화합물, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물
US20090186929A1 (en) * 2003-11-10 2009-07-23 U.S. Department Of Veterans Affairs Method and agent for inducing apoptosis/cell death in leukemia cells
US20050234026A1 (en) * 2003-11-10 2005-10-20 Weinberg Joe B Method and agent for inducing apoptosis/cell death in leukemia cells
US7364437B2 (en) * 2005-08-04 2008-04-29 Seagate Technology Llc Electronic device housing
CN101616736B (zh) 2007-02-19 2013-02-13 帝斯曼知识产权资产管理有限公司 含有铂族金属纳米颗粒的催化剂和生产铂族金属纳米颗粒分散体系的工艺
WO2018035046A1 (en) 2016-08-15 2018-02-22 President And Fellows Of Harvard College Treating infections using idsd from proteus mirabilis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100342275B1 (ko) * 1993-10-21 2002-12-05 지.디. 썰 엘엘씨 산화질소신타제저해제로서유용한아미디노유도체
US5629322A (en) * 1994-11-15 1997-05-13 Merck & Co., Inc. Cyclic amidine analogs as inhibitors of nitric oxide synthase
AU4149696A (en) * 1994-11-15 1996-06-06 Merck & Co., Inc. Substituted heterocycles as inhibitors of nitric oxide synthase
JPH11511741A (ja) * 1995-05-10 1999-10-12 ジー．ディー．サール アンド カンパニー 環状アミジン化合物から誘導される酸化窒素シンターゼインヒビター

Also Published As

Publication number Publication date
DE69802858T2 (de) 2002-08-08
NO310618B1 (no) 2001-07-30
PT870763E (pt) 2002-06-28
NO981658L (no) 1998-10-12
CN1202486A (zh) 1998-12-23
US6228866B1 (en) 2001-05-08
EP0870763B1 (en) 2001-12-12
HUP9800865A3 (en) 1999-03-01
AU746048B2 (en) 2002-04-11
EP0870763A1 (en) 1998-10-14
CA2234571A1 (en) 1998-10-10
TW427979B (en) 2001-04-01
ATE210647T1 (de) 2001-12-15
NO981658D0 (no) 1998-04-08
KR19980081287A (ko) 1998-11-25
AU6077798A (en) 1998-10-15
US6110930A (en) 2000-08-29
HU9800865D0 (en) 1998-05-28
HUP9800865A2 (hu) 1999-01-28
DE69802858D1 (de) 2002-01-24
DK0870763T3 (da) 2002-03-11

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