ATE210647T1 - Kondensierte piperin-derivate als stickstoffmonoxid-synthese-hemmer - Google Patents

Kondensierte piperin-derivate als stickstoffmonoxid-synthese-hemmer

Info

Publication number: ATE210647T1
Authority: AT; Austria
Prior art keywords: nitrogen monoxide; condensed; synthesis inhibitors; monoxide synthesis; piperine derivatives
Prior art date: 1997-04-10

Application number

AT98106569T

Other languages

English (en)

Inventor

Naoyuki Taniguchi

Kaoru Kobayashi

Masao Naka

Original Assignee

Ono Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-10

Filing date

1998-04-09

Publication date

2001-12-15

1998-04-09 Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE210647T1 publication Critical patent/ATE210647T1/de

Links

MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 4
239000003112 inhibitor Substances 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
MXXWOMGUGJBKIW-YPCIICBESA-N piperine Chemical class C=1C=C2OCOC2=CC=1/C=C/C=C/C(=O)N1CCCCC1 MXXWOMGUGJBKIW-YPCIICBESA-N 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT98106569T 1997-04-10 1998-04-09 Kondensierte piperin-derivate als stickstoffmonoxid-synthese-hemmer ATE210647T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP9183097		1997-04-10
JP27319697		1997-10-07

Publications (1)

Publication Number	Publication Date
ATE210647T1 true ATE210647T1 (de)	2001-12-15

Family

ID=26433266

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98106569T ATE210647T1 (de)	1997-04-10	1998-04-09	Kondensierte piperin-derivate als stickstoffmonoxid-synthese-hemmer

Country Status (14)

Country	Link
US (2)	US6110930A (de)
EP (1)	EP0870763B1 (de)
KR (1)	KR19980081287A (de)
CN (1)	CN1202486A (de)
AT (1)	ATE210647T1 (de)
AU (1)	AU746048B2 (de)
CA (1)	CA2234571A1 (de)
DE (1)	DE69802858T2 (de)
DK (1)	DK0870763T3 (de)
ES (1)	ES2169886T3 (de)
HU (1)	HUP9800865A3 (de)
NO (1)	NO310618B1 (de)
PT (1)	PT870763E (de)
TW (1)	TW427979B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2793248B1 (fr) *	1999-05-03	2001-06-29	Adir	Nouveaux derives de 2,3-methano-aminoacides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR20020008215A (ko) *	1999-06-09	2002-01-29	우에노 도시오	진통제
FR2794647A1 (fr) *	1999-06-11	2000-12-15	Centre Nat Rech Scient	Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
CN1370150A (zh) *	1999-06-22	2002-09-18	小野药品工业株式会社	药物中间体化合物的制造方法
FR2803298A1 (fr) *	1999-12-30	2001-07-06	Adir	Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2001058488A1 (en) *	2000-02-10	2001-08-16	Ono Pharmaceutical Co., Ltd.	Remedies for sjoegren's syndrome
AU2001296028A1 (en) *	2000-10-30	2002-05-15	Ono Pharmaceutical Co. Ltd.	Remedies for extraocular inflammatory diseases
WO2003022309A1 (fr) *	2001-09-10	2003-03-20	Ono Pharmaceutical Co., Ltd.	Remedes pour maladies allergiques
JP2006096665A (ja) *	2002-10-29	2006-04-13	Ono Pharmaceut Co Ltd	脊柱管狭窄症治療剤
US7846963B2 (en) *	2003-05-17	2010-12-07	Korea Research Institute Of Bioscience And Biotechnology	2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
KR100594377B1 (ko) *	2003-05-17	2006-06-30	한국생명공학연구원	항염증 활성을 갖는 신규 2-옥소-피페리딘 유도체(ⅰ)화합물, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물
US20050234026A1 (en) *	2003-11-10	2005-10-20	Weinberg Joe B	Method and agent for inducing apoptosis/cell death in leukemia cells
US20090186929A1 (en) *	2003-11-10	2009-07-23	U.S. Department Of Veterans Affairs	Method and agent for inducing apoptosis/cell death in leukemia cells
US7364437B2 (en) *	2005-08-04	2008-04-29	Seagate Technology Llc	Electronic device housing
EP2112955A2 (de)	2007-02-19	2009-11-04	DSM IP Assets B.V.	Neuartige pt-metallgruppenkatalysatoren und herstellungsverfahren dafür
US11246905B2 (en)	2016-08-15	2022-02-15	President And Fellows Of Harvard College	Treating infections using IdsD from Proteus mirabilis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100342275B1 (ko) *	1993-10-21	2002-12-05	지.디. 썰 엘엘씨	산화질소신타제저해제로서유용한아미디노유도체
US5629322A (en) *	1994-11-15	1997-05-13	Merck & Co., Inc.	Cyclic amidine analogs as inhibitors of nitric oxide synthase
AU4149696A (en) *	1994-11-15	1996-06-06	Merck & Co., Inc.	Substituted heterocycles as inhibitors of nitric oxide synthase
CN1190390A (zh) *	1995-05-10	1998-08-12	G.D.瑟尔公司	由环状脒衍生的氧化氮合成酶抑制剂

1998
- 1998-04-08 NO NO19981658A patent/NO310618B1/no not_active IP Right Cessation
- 1998-04-08 US US09/056,867 patent/US6110930A/en not_active Expired - Fee Related
- 1998-04-09 EP EP98106569A patent/EP0870763B1/de not_active Expired - Lifetime
- 1998-04-09 DK DK98106569T patent/DK0870763T3/da active
- 1998-04-09 TW TW087105329A patent/TW427979B/zh active
- 1998-04-09 CA CA002234571A patent/CA2234571A1/en not_active Abandoned
- 1998-04-09 AT AT98106569T patent/ATE210647T1/de not_active IP Right Cessation
- 1998-04-09 AU AU60777/98A patent/AU746048B2/en not_active Ceased
- 1998-04-09 ES ES98106569T patent/ES2169886T3/es not_active Expired - Lifetime
- 1998-04-09 PT PT98106569T patent/PT870763E/pt unknown
- 1998-04-09 DE DE69802858T patent/DE69802858T2/de not_active Expired - Fee Related
- 1998-04-09 CN CN98108834A patent/CN1202486A/zh active Pending
- 1998-04-10 KR KR1019980012758A patent/KR19980081287A/ko not_active Ceased
- 1998-04-10 HU HU9800865A patent/HUP9800865A3/hu unknown
2000
- 2000-03-13 US US09/524,255 patent/US6228866B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6110930A (en)	2000-08-29
HUP9800865A3 (en)	1999-03-01
CN1202486A (zh)	1998-12-23
HU9800865D0 (en)	1998-05-28
NO310618B1 (no)	2001-07-30
NO981658D0 (no)	1998-04-08
US6228866B1 (en)	2001-05-08
DE69802858T2 (de)	2002-08-08
AU6077798A (en)	1998-10-15
DE69802858D1 (de)	2002-01-24
AU746048B2 (en)	2002-04-11
DK0870763T3 (da)	2002-03-11
KR19980081287A (ko)	1998-11-25
TW427979B (en)	2001-04-01
HUP9800865A2 (hu)	1999-01-28
NO981658L (no)	1998-10-12
PT870763E (pt)	2002-06-28
ES2169886T3 (es)	2002-07-16
CA2234571A1 (en)	1998-10-10
EP0870763B1 (de)	2001-12-12
EP0870763A1 (de)	1998-10-14

Similar Documents

Publication	Publication Date	Title
ATE210647T1 (de)	2001-12-15	Kondensierte piperin-derivate als stickstoffmonoxid-synthese-hemmer
ES2182234T3 (es)	2003-03-01	Inhibidores de metaloproteasa.
DE69820248D1 (de)	2004-01-15	Pyrrolidin-derivate die eine phospholipase-a2-hemmende wirkung haben
WO2002100860A3 (fr)	2003-11-20	Composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
DE60032780D1 (de)	2007-02-15	Tetrahydroquinolin-derivate
NO20020925D0 (no)	2002-02-26	N-heterosykliske derivater som NOS-inhibitorer
IL156873A0 (en)	2004-02-08	Pharmaceutically active piperidine derivatives
DE60112272D1 (de)	2005-09-01	Imidazopyridin-derivate
ATE388958T1 (de)	2008-03-15	4'-c-substituierte 2-haloadenosinderivate
EP1415987A4 (de)	2004-08-18	Stickstoff-enthaltende aromatische ringverbindungen
ATE316967T1 (de)	2006-02-15	Zyklische amidderivate die cathepsin k hemmen
MXPA04001685A (es)	2004-05-31	Derivados de sulfonilamino empleados como herbicida.
EA200000826A1 (ru)	2001-04-23	Галоидированные производные амидиноаминокислот, применимые в качестве ингибиторов no-синтазы
EP1314712A4 (de)	2004-12-15	Substituierte benzoesäurederivate als nf-kappa-b-inhibitoren
DE60027144D1 (de)	2006-05-18	Hydroxamsäure-derivate
WO2000005214A3 (en)	2001-05-31	Isoquinolines as urokinase inhibitors
BR0210746A (pt)	2004-07-20	Derivados de 6-'2-(fosfonometóxi)alcóxi-pirimidina tendo atividade antiviral
PL361850A1 (en)	2004-10-04	Novel lipoic acid heterocyclic or benzene derivatives, preparation and use thereof as medicines
EP1571144A4 (de)	2007-08-01	Hydroxyalkylierte cyclischediaminverbindung
DE50311388D1 (de)	2009-05-20	Nicht-peptidische brs-3-agonisten
ES2172296T3 (es)	2002-09-16	Procedimiento de preparacion de sertralina racemica.
EP1118615A4 (de)	2002-02-27	Salze von pyridopyrazinderivaten und kristalle davon
ES2184633A1 (es)	2003-04-01	Procedimiento para la preparacion de derivados de 4-(imidazol-1-il) bencenosulfonamida.
EP1118327A4 (de)	2006-08-02	Vorbeugende und/oder therapeutische mittel zur behandlung der sinusitis.
AU2002214266A1 (en)	2002-05-21	Carbamate derivatives, process for producing the same and use thereof

Legal Events

Date	Code	Title	Description
2002-07-15	UEP	Publication of translation of european patent specification
2005-01-15	REN	Ceased due to non-payment of the annual fee