ES2170082T3 - Transactivador de mhc clase ii (ciita) y sus usos. - Google Patents

Transactivador de mhc clase ii (ciita) y sus usos.

Info

Publication number
ES2170082T3
ES2170082T3 ES94113378T ES94113378T ES2170082T3 ES 2170082 T3 ES2170082 T3 ES 2170082T3 ES 94113378 T ES94113378 T ES 94113378T ES 94113378 T ES94113378 T ES 94113378T ES 2170082 T3 ES2170082 T3 ES 2170082T3
Authority
ES
Spain
Prior art keywords
genes
mhc class
proteins
ciita
transactivator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94113378T
Other languages
English (en)
Inventor
Bernard Prof Mach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novimmune SA
Original Assignee
Novimmune SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novimmune SA filed Critical Novimmune SA
Application granted granted Critical
Publication of ES2170082T3 publication Critical patent/ES2170082T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Details Of Garments (AREA)
  • Credit Cards Or The Like (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Laminated Bodies (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE PRESENTAN GENES QUE CODIFICAN LAS PROTEINAS DE TRANSACCION Y QUE SON ESENCIALES PARA EL CONTROL GENERAL DE LA EXPRESION DE GENES DE MHC DE LA CLASE II DE VERTEBRADOS, PROTEINAS CODIFICADAS CON ESTOS GENES Y UN METODO PARA LA IDENTIFICACION DE TALES PROTEINAS DE TRANSACCION. ADEMAS, SE PRESENTAN TAMBIEN LAS SUSTANCIAS QUE PERMITEN LA REDUCCION DE LA EXPRESION ABERRANTE DE DICHOS GENES. Y AUN MAS, SE PRESENTAN VECTORES RECOMBINANTES QUE CONTIENEN DICHOS GENES, LOS ORGANISMOS HUESPEDES TRANSFORMADOS Y LOS METODOS PARA LA PRODUCCION DE LAS PROTEINAS CODIFICADAS POR DICHOS GENES. EN LA INVENCION TAMBIEN SE PRESENTAN COMPOSICIONES FARMACEUTICAS UTILES PARA EL TRATAMIENTO DE LAS ENFERMEDADES ASOCIADAS A LA EXPRESION DETERIORADA O ABERRANTE DE GENES DE MHC DE LA CLASE II.
ES94113378T 1993-08-26 1994-08-26 Transactivador de mhc clase ii (ciita) y sus usos. Expired - Lifetime ES2170082T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93113665 1993-08-26

Publications (1)

Publication Number Publication Date
ES2170082T3 true ES2170082T3 (es) 2002-08-01

Family

ID=8213211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94113378T Expired - Lifetime ES2170082T3 (es) 1993-08-26 1994-08-26 Transactivador de mhc clase ii (ciita) y sus usos.

Country Status (6)

Country Link
EP (1) EP0648836B1 (es)
AT (1) ATE211763T1 (es)
DE (1) DE69429608T2 (es)
DK (1) DK0648836T3 (es)
ES (1) ES2170082T3 (es)
PT (1) PT648836E (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672473A (en) * 1994-08-24 1997-09-30 President And Fellows Of Harvard College Methods of identifying compounds useful for treating autoimmune diseases
FR2762327B1 (fr) * 1997-04-22 1999-07-02 Transgene Sa Sequence d'acide nucleique de genes ciita, susceptibles d'etre impliquees dans le controle et la regulation de l'expression de genes codant pour des molecules mhc de type ii et leur utilisation, notamment comme medicament
US6410261B2 (en) * 1997-11-06 2002-06-25 President And Fellows Of Harvard College CIITA-interacting proteins and methods of use therefor
FR2775003A1 (fr) 1998-02-19 1999-08-20 Transgene Sa Methode de criblage de composes capables d'inhiber la fixation entre le facteur de transcription stat1 et le facteur de transcription usf1
AU2002347346A1 (en) * 2001-12-07 2003-06-17 University Of Liverpool Dna vaccine
WO2004009801A1 (de) * 2002-07-19 2004-01-29 Genethor Gmbh Nicht antigen präsentierende zellen zur selektion von t-zellen
WO2004047860A2 (de) * 2002-11-28 2004-06-10 Genethor Gmbh Nicht antigen präsentierende, mhc ii exprimierende zellen zur unterdrückung von pathologischen immunreaktionen
WO2005049860A2 (en) * 2003-11-05 2005-06-02 Karolinska Innovations Ab Diagnostic and therapeutic methods and assays

Also Published As

Publication number Publication date
DE69429608T2 (de) 2002-09-12
EP0648836B1 (en) 2002-01-09
EP0648836A1 (en) 1995-04-19
PT648836E (pt) 2002-06-28
DE69429608D1 (de) 2002-02-14
ATE211763T1 (de) 2002-01-15
DK0648836T3 (da) 2002-04-22

Similar Documents

Publication Publication Date Title
DE69434594D1 (de) Rekombinante adenoviren-vektor und verfahren zur verwendung
DE69635207D1 (de) Auf Chromosom 1 lokalisiertes Gen dessen Genprodukt mit der Alzheimerschen Krankheit assoziiert ist.
EP1439230A3 (en) Human transmembrane protein TMP-2 gene
ATE315087T1 (de) Neuartige auf p53 ansprechende gene
DK0721506T3 (da) Bakterielle eksporterede proteiner og acellulære vacciner baseret derpå
CY1106806T1 (el) Dna και πολυπεπτιδια ανθρωπινης tslp
WO1999053061A3 (en) Tumor associated nucleic acids and uses therefor
ATE263836T1 (de) Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür
GR852940B (es)
DK0648836T3 (da) MHC-klasse II-transaktivator (CIITA) og anvendelser deraf
DK295188D0 (da) Fibronectinbindende protein og fremgangsmaade til fremstilling heraf
DE69332514D1 (de) Transformation von Phaffia Rhodozyma
DK0613945T3 (da) Merlin-tumorsuppressorgen og anvendelser deraf
EP0815233A4 (en) NEW CYTOKININE FROM BIRDS AND CODING GENETIC SEQUENCES THEREFOR
ATE230025T1 (de) Proteinanaloge des ldl-rezeptors und deren kodierende gene
DK0781344T3 (da) Hidtil ukendt implantat og hidtil ukendt vektor til behandling af erhvervede sygdomme
DK57487D0 (da) Humant lymphotoxinpolypeptidderivat og fremgangsmaade til fremstilling deraf, dna-fragment, som koder for derivatet, rekombinante plasmider, som har inkorporeret fragmentet, og biologisk rene kulturer af mikroorganismer indeholdende saadanne plasmider
ATE190630T1 (de) Angiotensin-ii typ-1 rezeptor und dessen herstellung
DE69839765D1 (de) Lage-1 tumor-assozierte nukleinsäuren
SG49993A1 (en) Fused dna sequence fused protein expressed from said fused dna sequence and method for expressing said fused protein
ATE140928T1 (de) Proteine, die die expression von vertebraten-mhc- klasse-ii-genen regulieren, dafür kodierende dna- sequenzen und pharmazeutische zusammensetzungen
DE69519654D1 (de) htFIIIA Gen
NO20011961D0 (no) PRV-1-genet og anvendelsen av dette

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 648836

Country of ref document: ES