ES2170171T3 - Composicion de liberacion controlada que forma una estructura micelar inversa (l2) o una estructura micelar normal (l1). - Google Patents

Composicion de liberacion controlada que forma una estructura micelar inversa (l2) o una estructura micelar normal (l1).

Info

Publication number
ES2170171T3
ES2170171T3 ES95941306T ES95941306T ES2170171T3 ES 2170171 T3 ES2170171 T3 ES 2170171T3 ES 95941306 T ES95941306 T ES 95941306T ES 95941306 T ES95941306 T ES 95941306T ES 2170171 T3 ES2170171 T3 ES 2170171T3
Authority
ES
Spain
Prior art keywords
micelar
composition
mixture
reverse
normal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95941306T
Other languages
English (en)
Inventor
Kare Larsson
Helena Ljusberg-Wahren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Camurus AB
Original Assignee
Camurus AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Camurus AB filed Critical Camurus AB
Application granted granted Critical
Publication of ES2170171T3 publication Critical patent/ES2170171T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)

Abstract

COMPOSICION DE LKIBERACION CONTROLADA PARA UN MATERIAL ACTIVO BIOLOGICAMENTE, CARACTERIZADO EN QUE INCLUYE UNA MEZCLA DE: A) MONOCAPROINA, OPCIONALMENTE EN MEZCLA CON MONOCAPRILINA Y/O MONOCAPRINA, Y B) UN LIQUIDO POLAR SELECCIONADO ENTRE EL GRUPO INTEGRADO POR DICHOS LIQUIDOS POLARES QUE SON CAPACES DE FORMAR UNA FASE L2 CON A), Y C) UN MATERIAL ACTIVO BIOLOGICAMENTE DISUELTO O DISPERSO EN DICHA MEZCLA DE A) Y B), A) ESTANDO PRESENTE EN LA COMPOSICION, BASADO EN EL PESO TOTAL DE A)+B), EN UNA CANTIDAD QUE VA DEL LIMITE INFERIOR EN EL QUE LA MEZCLA DE A) Y B) FORMA UNA ESTRUCTURA MICELAR INVERSA (L2) Y HASTA UN 100% DE PESO DE A), CON LA CONDICION AÑADIDA DE QUE DICHA MEZCLA DE A) Y B) SE HALLA BASICAMENTE DENTRO DE ESE DOMINIO ESPECIFICO DE LA ESTRUCTURA L2, UN DIAGRAMA DE FASE, DONDE DICHA ESTRUCTURA L2 CAMBIARA A UNA ESTRUCTURA MICELAR NORMAL (L1) SI SE PONE EN CONTACTO CON UN LIQUIDO POLAR EXTERNO. ESTA COMPOSICION SE UTILIZA PREFERIBLEMENTE COMO UNA COMPOSICION MEDICA.
ES95941306T 1994-12-09 1995-12-08 Composicion de liberacion controlada que forma una estructura micelar inversa (l2) o una estructura micelar normal (l1). Expired - Lifetime ES2170171T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9404289A SE518619C2 (sv) 1994-12-09 1994-12-09 Komposition för reglerad frisättning innehållande monokaproin

Publications (1)

Publication Number Publication Date
ES2170171T3 true ES2170171T3 (es) 2002-08-01

Family

ID=20396276

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95941306T Expired - Lifetime ES2170171T3 (es) 1994-12-09 1995-12-08 Composicion de liberacion controlada que forma una estructura micelar inversa (l2) o una estructura micelar normal (l1).

Country Status (13)

Country Link
US (1) US5906831A (es)
EP (1) EP0790822B1 (es)
JP (1) JP3487860B2 (es)
AT (1) ATE213932T1 (es)
AU (1) AU4276896A (es)
BR (1) BR9509897A (es)
CA (1) CA2207218C (es)
DE (1) DE69525761T2 (es)
ES (1) ES2170171T3 (es)
FI (1) FI972415L (es)
NO (1) NO972614L (es)
SE (1) SE518619C2 (es)
WO (1) WO1996017597A1 (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
US20020153508A1 (en) * 2000-06-29 2002-10-24 Lynch Matthew Lawrence Cubic liquid crystalline compositions and methods for their preparation
EP2201965A1 (en) 2001-11-08 2010-06-30 Ziscoat N.V. Intraluminal device with a coating containing a therapeutic agent
DE60231549D1 (de) * 2001-12-03 2009-04-23 Dor Biopharma Inc Stabilisierte umkehr-mizellen-zusammensetzungen und ihre verwendung
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US9592324B2 (en) 2006-11-06 2017-03-14 Atrium Medical Corporation Tissue separating device with reinforced support for anchoring mechanisms
WO2007011385A2 (en) 2004-09-28 2007-01-25 Atrium Medical Corporation Heat cured gel and method of making
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US20060083768A1 (en) * 2004-09-28 2006-04-20 Atrium Medical Corporation Method of thickening a coating using a drug
US8312836B2 (en) 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
WO2006037049A2 (en) * 2004-09-28 2006-04-06 Atrium Medical Corporation Application of a coating on a medical device
US8124127B2 (en) 2005-10-15 2012-02-28 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US20060127437A1 (en) * 2004-12-13 2006-06-15 Misty Anderson Kennedy Semisolid system and combination semisolid, multiparticulate system for sealing tissues and/or controlling biological fluids
US20070059350A1 (en) * 2004-12-13 2007-03-15 Kennedy John P Agents for controlling biological fluids and methods of use thereof
US8535709B2 (en) * 2004-12-13 2013-09-17 Southeastern Medical Technologies, Llc Agents for controlling biological fluids and methods of use thereof
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US7670997B2 (en) * 2006-06-08 2010-03-02 Bausch & Lomb Incorporated Ophthalmic compositions comprising a branched, glycerol monoalkyl compound and a fatty acid monoester
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
KR20140143461A (ko) 2007-08-06 2014-12-16 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
SI2712622T1 (sl) * 2008-05-21 2016-10-28 Ferring B.V. Orodisperzibilni dezmopresin za povečanje začetnega obdobja spanja nemotenega z nokturijo
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9744542B2 (en) 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
EP3298024B1 (en) 2015-05-20 2020-04-01 Apeel Technology, Inc. Plant extract compositions and methods of preparation thereof
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
EP3349589B1 (en) 2015-09-16 2022-12-14 Apeel Technology, Inc. Method for forming a protective coating by applying fatty acid glyceride compounds to a surface
ES2797697T3 (es) 2015-12-10 2020-12-03 Apeel Tech Inc Proceso para despolimerizar cutina
WO2017132281A1 (en) 2016-01-26 2017-08-03 Apeel Technology, Inc. Method for preparing and preserving sanitized products
JP7194678B2 (ja) 2016-11-17 2022-12-22 アピール テクノロジー，インコーポレイテッド 植物抽出物から形成される組成物及びその調製方法
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
US12150945B2 (en) 2018-07-20 2024-11-26 Lipocine Inc. Liver disease
US12245605B2 (en) 2018-09-05 2025-03-11 Apeel Technology, Inc. Compounds and formulations for protective coatings
JP7578707B2 (ja) 2020-03-04 2024-11-06 アピール テクノロジー，インコーポレイテッド 被覆された農産物及び対応する方法
MX2023004343A (es) 2020-10-30 2023-05-08 Apeel Tech Inc Composiciones y metodos de preparacion de las mismas.
CN116456961B (zh) * 2020-11-04 2026-01-30 伊诺莱克斯投资公司 生物基甘油庚酸酯组合物及其制备方法和应用
CN118159138A (zh) 2021-09-08 2024-06-07 阿比尔技术公司 用于保护性涂层的化合物和制剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8206744D0 (sv) 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
SE457693B (sv) * 1986-07-01 1989-01-23 Drilletten Ab Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas

Also Published As

Publication number Publication date
AU4276896A (en) 1996-06-26
JPH10510260A (ja) 1998-10-06
WO1996017597A1 (en) 1996-06-13
NO972614D0 (no) 1997-06-06
DE69525761D1 (de) 2002-04-11
FI972415A0 (fi) 1997-06-06
SE518619C2 (sv) 2002-10-29
BR9509897A (pt) 1997-12-30
FI972415A7 (fi) 1997-06-06
EP0790822B1 (en) 2002-03-06
NO972614L (no) 1997-06-06
SE9404289L (sv) 1996-06-10
SE9404289D0 (sv) 1994-12-09
ATE213932T1 (de) 2002-03-15
JP3487860B2 (ja) 2004-01-19
EP0790822A1 (en) 1997-08-27
FI972415L (fi) 1997-06-06
CA2207218C (en) 2002-02-12
US5906831A (en) 1999-05-25
CA2207218A1 (en) 1996-06-13
DE69525761T2 (de) 2002-10-24

Similar Documents

Publication Publication Date Title
TR200002098T2 (tr) Yumuşak emici kağıt ürünleri.
ES2119217T3 (es) Espuma de adhesivo elastomero.
ES2093412T3 (es) Composicion cosmetica en forma de polvo que contiene un ligante graso siliconado.
ES2171186T3 (es) Composiciones liquidas de difusion.
PE20000792A1 (es) Articulo absorbente que incluye un agente de complejificacion ionica para heces
ES2053649T3 (es) Polimeros hidrofilicos para incorporar desodorantes en estructuras absorbentes.
DE69209490D1 (de) Zusammensetzung und mit derselben behandelte Polymergewebe
PE22991A1 (es) Composicion desodorante conteniendo carbon
ES2126144T3 (es) Composicion topica para el cuidado personal que contiene un polimero adhesivo injertado con polisiloxano y un coadyuvante de secado.
PE20000721A1 (es) Articulo absorbente que incluye un agente modificador de heces basado en calcio
ES2117136T3 (es) Metodo y dispositivo para acolchar extremidades.
CO5570652A2 (es) Productos en gel para la axila, con componente de bloqueo de agua
CO4230158A1 (es) Composiciones para el arreglo del cabello
BR9713672A (pt) Fibra multicomponente
SE8404568L (sv) Mikrofasseparerade vattengeler for reglerad frigoring av bioaktiva material
ES2132252T3 (es) Estructura absorbente estirable.
PE20001263A1 (es) Telas no tejidas dispersables en agua que contienen materiales unidores polimericos sensibles al ion o sensibles a la temperatura y proceso para hacer telas
ES2044825T1 (es) Formulaciones de matriz de liberacion sostenida.
ES2081574T3 (es) Composiciones de liberacion lenta.
BR0212026A (pt) Sistema terapêutico transdérmico com fentanila ou substâncias análogas
ES2061019T3 (es) Vendaje elastico tejido o de punto.
SE9404289D0 (sv) Controlled release
BR0117123A (pt) Dispositivo de retenção gástrica expansìvel
BR9909486A (pt) Compostos calcilìticos
ES2084105T3 (es) Agente acondicionador de tejidos en laminas para secadoras, que contiene siliconas compatibles.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 790822

Country of ref document: ES