ES2170769T3 - Procedimiento de tratamiento de secreciones pulmonares retenidas. - Google Patents

Procedimiento de tratamiento de secreciones pulmonares retenidas.

Info

Publication number
ES2170769T3
ES2170769T3 ES94919422T ES94919422T ES2170769T3 ES 2170769 T3 ES2170769 T3 ES 2170769T3 ES 94919422 T ES94919422 T ES 94919422T ES 94919422 T ES94919422 T ES 94919422T ES 2170769 T3 ES2170769 T3 ES 2170769T3
Authority
ES
Spain
Prior art keywords
subject
treatment
lantibiotic
administration
presented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94919422T
Other languages
English (en)
Inventor
Y Vedia Luis M Molina
Monroe Jackson Stutts
Richard C Boucher Jr
David C Henke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of North Carolina at Chapel Hill
Molichem Medicines Inc
Original Assignee
University of North Carolina at Chapel Hill
Molichem Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill, Molichem Medicines Inc filed Critical University of North Carolina at Chapel Hill
Application granted granted Critical
Publication of ES2170769T3 publication Critical patent/ES2170769T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Steroid Compounds (AREA)

Abstract

SE PRESENTA UN METODO PARA FACILITAR LA LIMPIEZA DE SECRECIONES PULMONARES RETENIDAS EN UN SUJETO UTILIZANDO LANTIBIOTICOS. EL METODO COMPRENDE LA ADMINISTRACION A LOS PULMONES DEL SUJETO DE UNA CANTIDAD EFECTIVA DE UN LANTIBIOTICO. EL LANTIBIOTICO SE ADMINISTRA PREFERIBLEMENTE MEDIANTE APLICACION TOPICA EN EL EPITELIO RESPIRATORIO, TAL COMO MEDIANTE LA GENERACION DE UN AEROSOL DEL MISMO QUE LUEGO ES INHALADO POR EL SUJETO. UN LANTIBIOTICO PREFERIDO PARA LLEVAR A CABO LA INVENCION ES LA DURAMICINA. EL METODO PUEDE UTILIZARSE EN EL TRATAMIENTO DE ENFERMEDADES TALES COMO LA FIBROSIS CISTICA, LA BRONQUITIS CRONICA Y EL ASMA. TAMBIEN SE PRESENTA UN METODO PARA COMBINAR LA TUBERCULOSIS QUE COMPRENDE LA ADMINISTRACION DE UN LANTIBIOTICO A UN SUJETO QUE NECESITE EL TRATAMIENTO.
ES94919422T 1993-06-09 1994-06-08 Procedimiento de tratamiento de secreciones pulmonares retenidas. Expired - Lifetime ES2170769T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/074,315 US5512269A (en) 1993-06-09 1993-06-09 Method of treating retained pulmonary secretions
PCT/US1994/006486 WO1994028726A2 (en) 1993-06-09 1994-06-08 Method of treating retained pulmonary secretions

Publications (1)

Publication Number Publication Date
ES2170769T3 true ES2170769T3 (es) 2002-08-16

Family

ID=22118924

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94919422T Expired - Lifetime ES2170769T3 (es) 1993-06-09 1994-06-08 Procedimiento de tratamiento de secreciones pulmonares retenidas.

Country Status (11)

Country Link
US (5) US5512269A (es)
EP (2) EP0764028B1 (es)
JP (2) JP4027968B2 (es)
AT (1) ATE212854T1 (es)
AU (1) AU696374B2 (es)
CA (1) CA2164517C (es)
DE (1) DE69429832T2 (es)
DK (1) DK0764028T3 (es)
ES (1) ES2170769T3 (es)
PT (1) PT764028E (es)
WO (1) WO1994028726A2 (es)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656256A (en) * 1994-12-14 1997-08-12 The University Of North Carolina At Chapel Hill Methods of treating lung disease by an aerosol containing benzamil or phenamil
US5908611A (en) * 1995-05-05 1999-06-01 The Scripps Research Institute Treatment of viscous mucous-associated diseases
US5635160A (en) * 1995-06-07 1997-06-03 The University Of North Carolina At Chapel Hill Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
US5866539A (en) * 1995-06-23 1999-02-02 Ambi Inc. Method for the control of antibiotic-resistant gram positive bacteria and treatment of infection
US5910479A (en) * 1996-10-18 1999-06-08 Ambi Inc. Method for the treatment of Streptococcus pneumoniae infection
DE19745583A1 (de) * 1997-10-15 1999-04-22 Hoechst Marion Roussel De Gmbh Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben
CA2332369A1 (en) * 1998-05-27 1999-12-02 Euroceltique S.A. Drug delivery system comprising a tightly compacted solid medicament stock
US6323191B1 (en) 1998-06-19 2001-11-27 Genzyme Corporation Small molecule chloride transport
BR9912053A (pt) * 1998-07-13 2001-04-03 Univ Texas Processos de tratamento de câncer utilizando conjugados terapêuticos que se ligam a aminofosfolipìdios
US6818213B1 (en) * 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
CN1348377A (zh) * 1998-12-17 2002-05-08 希龙公司 用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法
US8501911B2 (en) * 1999-02-24 2013-08-06 Biomarck Pharmaceuticals, Ltd Methods of reducing inflammation and mucus hypersecretion
US7544772B2 (en) 2001-06-26 2009-06-09 Biomarck Pharmaceuticals, Ltd. Methods for regulating inflammatory mediators and peptides useful therein
JP4969002B2 (ja) * 1999-06-08 2012-07-04 ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン ｒＡＡＶ形質導入を増加するための化合物および方法
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6245320B1 (en) * 1999-09-01 2001-06-12 University Of Maryland Inhibition of mucin release from airway goblet cells by polycationic peptides
US7241447B1 (en) * 1999-10-07 2007-07-10 University Of Iowa Research Foundation Adeno-associated virus vectors and uses thereof
US7919469B2 (en) 2000-02-24 2011-04-05 North Carolina State University Methods and compositions for altering mucus secretion
US7265088B1 (en) 2000-02-24 2007-09-04 North Carolina State University Method and compositions for altering mucus secretion
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
CN1642524B (zh) * 2002-03-12 2011-05-18 微计量治疗公司 通过吸入部位特异性递送联合施用的药物
US7511124B2 (en) * 2002-07-15 2009-03-31 Board Of Regents, The University Of Texas System Compositions comprising phosphatidylethanolamine-binding peptides linked to anti-viral agents
US7378386B2 (en) * 2002-07-15 2008-05-27 Board Of Regents, The University Of Texas System Anti-viral treatment methods using phosphatidylethanolamine-binding peptide derivatives
DE60335383D1 (de) 2002-07-15 2011-01-27 Univ Texas Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen
US7384909B2 (en) 2002-07-15 2008-06-10 Board Of Regents, The University Of Texas System Anti-viral treatment methods using phosphatidylethanolamine-binding peptides linked to anti-viral agents
US7879801B2 (en) * 2002-07-15 2011-02-01 Board Of Regents, The University Of Texas System Compositions comprising cell-impermeant duramycin derivatives
US7678386B2 (en) 2002-07-15 2010-03-16 Board Of Regents The University Of Texas Liposomes coated with selected antibodies that bind to aminophospholipids
US7828739B2 (en) * 2002-08-27 2010-11-09 Precision Pulsus, Inc. Apnea detection system
US6869402B2 (en) * 2002-08-27 2005-03-22 Precision Pulsus, Inc. Method and apparatus for measuring pulsus paradoxus
EP1558746A4 (en) * 2002-10-10 2006-11-22 Molichem Medicines Inc DURAMYCIN-CODING NUCLEIC ACIDS
MXPA05004121A (es) * 2002-10-18 2006-02-17 Molichem Medicines Inc Metodos para tratar la enfermedad de ojo reseco con lantibioticos.
DE10261782A1 (de) * 2002-12-19 2004-07-01 Dr. Petry Genmedics Gmbh Neue Gene und Genprodukte
WO2004080427A2 (en) * 2003-03-12 2004-09-23 Schneider Daniel J Method of preventing and treating infections that attack mucosa and assisting rehabilitation thereafter using topically applied ascorbic acid
WO2004089423A2 (en) * 2003-03-31 2004-10-21 University Of Iowa Research Foundation Pharmico-gene theraphy of epithelial sodium channel associated disoders
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
CA2565545A1 (en) * 2004-05-06 2005-12-08 Molichem Medicines, Inc. Treatment of ocular diseases and disorders using lantibiotic compositions
WO2005107787A1 (en) * 2004-05-06 2005-11-17 Molichem Medicines, Inc. Treatment of membrane-associated diseases and disorders using lantibiotic containing compositions
WO2006078899A2 (en) 2005-01-20 2006-07-27 Biomarck Pharmaceuticals, Ltd. Mucin hypersecretion inhibitors based on the structure of mans and methods of use
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
AU2006297289B2 (en) 2005-09-29 2013-03-21 Novartis Ag Antibiotic formulations, unit doses, kits, and methods
WO2007076053A2 (en) * 2005-12-21 2007-07-05 Nitrox, Llc Stable s-nitrosothiol formulations
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
WO2007092582A2 (en) * 2006-02-08 2007-08-16 Biosynexus Incorporated Neutralization of bacterial spores
EP2019964A2 (en) * 2006-04-28 2009-02-04 University of Iowa Research Foundation Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection. method to identify a viral receptor or co-receptor
SG10201500418QA (en) 2006-07-26 2015-03-30 Biomarck Pharmaceuticals Ltd Methods for attenuating release of inflammatory mediators and peptides useful therein
US20080138397A1 (en) * 2006-10-24 2008-06-12 Aradigm Corporation Processes for taste-masking of inhaled formulations
GB0714030D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
WO2009141264A2 (en) * 2008-05-20 2009-11-26 Boehringer Ingelheim Vetmedica Gmbh Gallidermin to treat infections of the respiratory tract
DK2387580T3 (da) 2009-01-14 2014-10-13 Novacta Biosystems Ltd Deoxyactagardinderivater
EA020733B1 (ru) 2009-02-04 2015-01-30 Новакта Биосистемс Лимитед Производные актагардина
CN102665807A (zh) 2010-01-05 2012-09-12 微剂量治疗技术公司 吸入设备和方法
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) * 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
RU2671976C2 (ru) 2012-12-17 2018-11-08 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4-фенилбутил)карбамимидоил)пиразин-2-карбоксамида
HUE032891T2 (hu) 2012-12-17 2017-11-28 Parion Sciences Inc Klórpirazin-karboxamid-származékok nem kielégítõ nyálkahártya-hidratáció által elõsegített megbetegedések kezelésére
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
WO2017139381A1 (en) 2016-02-08 2017-08-17 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
WO2017155973A1 (en) 2016-03-07 2017-09-14 University Of Iowa Research Foundation Aav-mediated expression using a synthetic promoter and enhancer
US12173305B2 (en) 2016-05-26 2024-12-24 University Of Iowa Research Foundation cis and trans requirements for terminal resolution of human bocavirus 1
US11142775B2 (en) 2017-01-13 2021-10-12 University Of Iowa Research Foundation Bocaparvovirus small noncoding RNA and uses thereof
CN114302706A (zh) 2019-06-17 2022-04-08 碧奥马尔克制药有限公司 治疗葡萄膜炎的肽及其使用方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683072A (en) * 1968-03-14 1972-08-08 William J Miller A methobottromycin and process for treating poultry infections
US4501729A (en) * 1982-12-13 1985-02-26 Research Corporation Aerosolized amiloride treatment of retained pulmonary secretions
JPS6234923A (ja) * 1985-08-09 1987-02-14 Hitachi Ltd 新規な重合体
ES2032831T5 (es) * 1986-08-19 2001-02-16 Genentech Inc Dispositivo y dispersion para suministro intrapulmonar de factores de crecimiento polipeptidos y citoquinas.
ATE101490T1 (de) * 1988-06-22 1994-03-15 Applied Microbiology Inc Nisin-zusammensetzungen zur anwendung als erhoehte breit-spektrum-bakterizide.
US5135910A (en) * 1988-06-22 1992-08-04 The Public Health Research Institute Of The City Of New York Nisin compositions for use as enhanced, broad range bactericides
US4980163A (en) * 1989-03-01 1990-12-25 Public Health Research Institute Of The City Of New York Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection
DE3938140A1 (de) * 1989-11-16 1991-08-08 Beiersdorf Ag Desodorierende kosmetische mittel
JPH05963A (ja) * 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
US5162348A (en) * 1990-05-24 1992-11-10 Imperial Chemical Industries Plc Treatment of cystic fibrosis
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
JPH05500229A (ja) * 1991-04-12 1993-01-21 東レ株式会社 固体ポリペプチド微粒子のエアロゾル製剤とその製造方法
US5559096A (en) * 1991-04-15 1996-09-24 Applied Microbiology, Inc. Pharmaceutical compositions against gastric disorders
US5292498A (en) * 1991-06-19 1994-03-08 The University Of North Carolina At Chapel Hill Method of treating lung disease with uridine triphosphates
US5384128A (en) * 1993-03-02 1995-01-24 University Of Alabama Research Foundation Method of and compounds for treatment for cystic fibrosis

Also Published As

Publication number Publication date
US5716931A (en) 1998-02-10
US5849706A (en) 1998-12-15
WO1994028726A2 (en) 1994-12-22
DK0764028T3 (da) 2002-03-18
DE69429832T2 (de) 2002-08-14
WO1994028726A3 (en) 1995-03-02
CA2164517A1 (en) 1994-12-22
PT764028E (pt) 2002-06-28
EP0764028B1 (en) 2002-02-06
JP2005206612A (ja) 2005-08-04
JPH09501413A (ja) 1997-02-10
US5651957A (en) 1997-07-29
EP1166794A2 (en) 2002-01-02
US5512269A (en) 1996-04-30
EP1166794A3 (en) 2003-03-12
ATE212854T1 (de) 2002-02-15
EP0764028A2 (en) 1997-03-26
DE69429832D1 (de) 2002-03-21
AU696374B2 (en) 1998-09-10
US5683675A (en) 1997-11-04
JP4027968B2 (ja) 2007-12-26
CA2164517C (en) 2010-01-19
AU7057894A (en) 1995-01-03

Similar Documents

Publication Publication Date Title
DK0764028T3 (da) Fremgangsmåde til behandling af tilbageholdte lungesekretioner
AR008721A1 (es) Nueva composicion medicamentosa acuosa y su utilizacion para la produccion de aerosoles libres de gas propulsor
NO305345B1 (no) Inhalasjonsapparat uten drivgass
FI951465A0 (fi) Parathormonin aktiivisten fragmenttien annostelu keuhkojen kautta
PE44995A1 (es) Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
ECSP024268A (es) Nuevos polvos para inhalacion que contienen tiotropio
MEP30108A (en) Formoterol superfine formulation
ES2176355T3 (es) Formulaciones de aerosol de peptidos y proteinas.
DE60114571D1 (de) Zubereitungen mit einem anticholinergischen wirkstoff für die behandlung der chronischen obstruktiven lungenerkrankung
NZ507151A (en) Pulmonary and nasal delivery of raloxifene
ATE216575T1 (de) Treibgasmischung für eine aerosolzubereitung
EA200401305A1 (ru) Аэрозольная композиция для ингаляции, содержащая соль тиотропия
CA2356404A1 (en) Method for accelerating the rate of mucociliary clearance
Parks Mist therapy: Rationale and practice
EA202191506A1 (ru) Терапевтическая композиция интраназального лидокаина
MX2024006942A (es) Composicion farmaceutica que comprende salbutamol.
EP1110547A3 (en) Helium and neon as means delivering drug in inhaler
AHLGREN Aerosol drug therapy
DE569583C (de) Hochfrequenz-Inhalator
SAKAKURA A NOTE ON PENICILLIN NEBULIZER THERAPY FOR CHRONIC PARASINUSITIS
Miller How to use aerosols effectively
Segal Inhalation Therapy
JP2021102606A (ja) 繊毛運動活性化剤
TH55704A3 (th) วิธีการสำหรับการเร่งอัตราของการชำระด้วยขนเซลล์เมือก
RO133818B1 (ro) Compoziţie pe bază de ape minerale sulfuroase şi utilizare

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 764028

Country of ref document: ES