ES2170997T3 - Un procedimiento para preparar acido 2-hidroxi-metil-3-fenilpropionico opticamente activo. - Google Patents
Un procedimiento para preparar acido 2-hidroxi-metil-3-fenilpropionico opticamente activo.Info
- Publication number
- ES2170997T3 ES2170997T3 ES98308053T ES98308053T ES2170997T3 ES 2170997 T3 ES2170997 T3 ES 2170997T3 ES 98308053 T ES98308053 T ES 98308053T ES 98308053 T ES98308053 T ES 98308053T ES 2170997 T3 ES2170997 T3 ES 2170997T3
- Authority
- ES
- Spain
- Prior art keywords
- optically active
- methyl
- procedure
- hydroxy
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RDUHFHDKXQBHMH-UHFFFAOYSA-N 2-benzyl-3-hydroxypropanoic acid Chemical compound OCC(C(O)=O)CC1=CC=CC=C1 RDUHFHDKXQBHMH-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- -1 AMINO Chemical class 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE PRESENTA UN PROCEDIMIENTO VIABLE INDUSTRIALMENTE PARA LA PREPARACION DE ACIDO 2 - HIDROXIMETIL - 3 - FENILPROPIONICO OPTICAMENTE ACTIVO SEGUN EL CUAL SE PUEDE RESOLVER DE MANERA EFICAZ UN ACIDO (RS) - 2 - HIDROXIMETIL - 3 FENILPROPIONICO MEDIANTE LA CRISTALIZACION DE UNA SAL AMINA OPTICAMENTE ACTIVA SIENDO DICHA SAL AMINA OPTICAMENTE ACTIVA UNA SAL CIS - 1 AMINO - 3 - INDANOLICA OPTICAMENTE ACTIVA, UNA SAL AL METILBENCILAMINA OPTICAMENTE ACTIVA O UNA SAL 3 - METIL - 2 FENIL - 1 - BUTILAMINA OPTICAMENTE ACTIVA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9270680A JPH11106363A (ja) | 1997-10-03 | 1997-10-03 | 光学活性2−ヒドロキシメチル−3−フェニルプロピオン酸の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170997T3 true ES2170997T3 (es) | 2002-08-16 |
Family
ID=17489458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98308053T Expired - Lifetime ES2170997T3 (es) | 1997-10-03 | 1998-10-02 | Un procedimiento para preparar acido 2-hidroxi-metil-3-fenilpropionico opticamente activo. |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US6028217A (es) |
| EP (1) | EP0906900B1 (es) |
| JP (1) | JPH11106363A (es) |
| DE (1) | DE69803528T2 (es) |
| ES (1) | ES2170997T3 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0937710B1 (en) | 1998-02-16 | 2003-04-16 | Ajinomoto Co., Inc. | Method for producing an optically active phenylpropionic acid derivative |
| JP2002167381A (ja) * | 2000-08-03 | 2002-06-11 | Kuraray Co Ltd | (±)−6−ヒドロキシ−2,5,7,8−テトラメチルクロマン−2−カルボン酸の光学分割法 |
| CN109232220B (zh) * | 2017-09-15 | 2021-09-10 | 上海健康医学院 | 一种3-羟基-3-苯基丙酸类化合物的化学拆分方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4904822A (en) * | 1988-02-19 | 1990-02-27 | Kuraray Co., Ltd. | Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid |
| FR2744446B1 (fr) * | 1996-02-05 | 1998-04-17 | Bioprojet Soc Civ | Procede de synthese asymetrique des derives s-acyles de l'acide 2-mercaptomethyl 3-phenyl propanoique, application a la synthese de derives n-(mercaptoacyl) amino-acides |
-
1997
- 1997-10-03 JP JP9270680A patent/JPH11106363A/ja active Pending
-
1998
- 1998-10-02 ES ES98308053T patent/ES2170997T3/es not_active Expired - Lifetime
- 1998-10-02 EP EP98308053A patent/EP0906900B1/en not_active Expired - Lifetime
- 1998-10-02 DE DE69803528T patent/DE69803528T2/de not_active Expired - Lifetime
- 1998-10-05 US US09/166,124 patent/US6028217A/en not_active Expired - Fee Related
-
1999
- 1999-11-30 US US09/450,740 patent/US6093846A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69803528T2 (de) | 2002-10-02 |
| JPH11106363A (ja) | 1999-04-20 |
| EP0906900B1 (en) | 2002-01-23 |
| DE69803528D1 (de) | 2002-03-14 |
| US6028217A (en) | 2000-02-22 |
| US6093846A (en) | 2000-07-25 |
| EP0906900A1 (en) | 1999-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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