ES2172949T3 - Composiciones destinadas para la administracion transcutanea y cutanea de agentes biologicamente activos. - Google Patents
Composiciones destinadas para la administracion transcutanea y cutanea de agentes biologicamente activos.Info
- Publication number
- ES2172949T3 ES2172949T3 ES98962674T ES98962674T ES2172949T3 ES 2172949 T3 ES2172949 T3 ES 2172949T3 ES 98962674 T ES98962674 T ES 98962674T ES 98962674 T ES98962674 T ES 98962674T ES 2172949 T3 ES2172949 T3 ES 2172949T3
- Authority
- ES
- Spain
- Prior art keywords
- active agents
- biologically active
- transcutaneous
- compositions intended
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001735 carboxylic acids Chemical class 0.000 abstract 2
- 239000004820 Pressure-sensitive adhesive Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una composición para la administración transdermal y dermal de agentes biológicamente activos, que comprende una cantidad efectiva de uno o más agentes biológicamente activos, uno o más mejoradores de penetración elegidos del grupo que consta de monoalcanolamidas y dialcanolamidas de ácidos carboxílicos que tienen al menos 8 átomos de carbono, donde los grupos hidroxialquilo contienen de 2 a 21 átomos de carbono, uno o más adyuvantes de absorción elegidos del grupo que consta de monoetanolamidas y dietanolamidas de ácidos carboxílicos que tienen de 1 a 4 átomos de carbono y, opcionalmente, además adyuvantes y excipientes de permeación biológicamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97RM000808A IT1297139B1 (it) | 1997-12-23 | 1997-12-23 | Composizioni per la somministrazione transdermica e dermica di sostanze biologicamente attive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2172949T3 true ES2172949T3 (es) | 2002-10-01 |
Family
ID=11405416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98962674T Expired - Lifetime ES2172949T3 (es) | 1997-12-23 | 1998-12-21 | Composiciones destinadas para la administracion transcutanea y cutanea de agentes biologicamente activos. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1043979B1 (es) |
| AT (1) | ATE212222T1 (es) |
| AU (1) | AU1783699A (es) |
| DE (1) | DE69803607T2 (es) |
| ES (1) | ES2172949T3 (es) |
| IT (1) | IT1297139B1 (es) |
| WO (1) | WO1999032094A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10114382A1 (de) * | 2001-03-23 | 2002-09-26 | Beiersdorf Ag | Feuchtigkeitsaufnehmende Matrix auf Silikonbasis insbesondere zur Wundversorgung und/oder pharmazeutisch/kosmetischen Hautbehandlung |
| WO2009066457A1 (ja) * | 2007-11-22 | 2009-05-28 | Medrx Co., Ltd. | 脂肪酸系イオン液体を有効成分とする外用剤組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5314694A (en) * | 1990-10-29 | 1994-05-24 | Alza Corporation | Transdermal formulations, methods and devices |
| EP0737477A4 (en) * | 1993-12-27 | 1998-04-01 | Akzo Nobel Nv | TRANSDERMAL PHARMACEUTICAL PREPARATION |
| US5612382A (en) * | 1994-07-15 | 1997-03-18 | Frances B. Fike | Composition for percutaneous absorption of pharmaceutically active ingredients |
-
1997
- 1997-12-23 IT IT97RM000808A patent/IT1297139B1/it active IP Right Grant
-
1998
- 1998-12-21 DE DE69803607T patent/DE69803607T2/de not_active Expired - Fee Related
- 1998-12-21 AT AT98962674T patent/ATE212222T1/de not_active IP Right Cessation
- 1998-12-21 WO PCT/IT1998/000374 patent/WO1999032094A1/en not_active Ceased
- 1998-12-21 AU AU17836/99A patent/AU1783699A/en not_active Abandoned
- 1998-12-21 EP EP98962674A patent/EP1043979B1/en not_active Expired - Lifetime
- 1998-12-21 ES ES98962674T patent/ES2172949T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE212222T1 (de) | 2002-02-15 |
| IT1297139B1 (it) | 1999-08-03 |
| DE69803607T2 (de) | 2002-09-12 |
| EP1043979A1 (en) | 2000-10-18 |
| WO1999032094A1 (en) | 1999-07-01 |
| DE69803607D1 (de) | 2002-03-14 |
| EP1043979B1 (en) | 2002-01-23 |
| AU1783699A (en) | 1999-07-12 |
| ITRM970808A1 (it) | 1999-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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