ES2173953T3 - Uso de il-12 y antagonistas de il-12 para la fabricacion de una composicion farmaceutica para el tratamiento de enfermedades autoinmunes. - Google Patents

Uso de il-12 y antagonistas de il-12 para la fabricacion de una composicion farmaceutica para el tratamiento de enfermedades autoinmunes.

Info

Publication number
ES2173953T3
ES2173953T3 ES95912666T ES95912666T ES2173953T3 ES 2173953 T3 ES2173953 T3 ES 2173953T3 ES 95912666 T ES95912666 T ES 95912666T ES 95912666 T ES95912666 T ES 95912666T ES 2173953 T3 ES2173953 T3 ES 2173953T3
Authority
ES
Spain
Prior art keywords
autoimmune
treatment
antagonists
manufacture
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95912666T
Other languages
English (en)
Other versions
ES2173953T5 (es
Inventor
John P Leonard
Samuel Goldman
Richard O'hara Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22791827&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2173953(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Application granted granted Critical
Publication of ES2173953T3 publication Critical patent/ES2173953T3/es
Publication of ES2173953T5 publication Critical patent/ES2173953T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBEN METODOS DE TRATAMIENTOS DE ESTADOS AUTOINMUNES QUE CONSISTEN EN LA ADMINISTRACION A UN MAMIFERO DE IL-12 O UN ANTAGONISTA DE IL-12. EN ALGUNAS DE LAS INCORPORACIONES PREFERENTES, LA CONDICION AUTOINMUNE SE POTENCIA POR UN AUMENTO DE LOS NIVELES DE IFN-{GA} O TNF-{AL}. LOS ESTADOS ADECUADOS PARA EL TRATAMIENTO INCLUYEN LA ESCLEROSIS MULTIPLE, EL LUPUS ERITEMATOSO SISTEMICO, LA ARTRITIS REUMATOIDE, LA INFLAMACION PULMONAR AUTOINMUNE, EL SINDROME DE GUILLAIN-BARRE, LA TIROIDITIS AUTOINMUNE, LA DIABETES MELLITUS DEPENDIENTE DE INSULINA Y LA ENFERMEDAD OCULAR INFLAMATORIA AUTOINMUNE.
ES95912666T 1994-03-14 1995-03-07 Uso del il-12 y antagonistas del il-12 para la fabricacion de una composicion farmaceutica para el tratamiento de enfermedades autoinmunes. Expired - Lifetime ES2173953T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21262994A 1994-03-14 1994-03-14
US212629 1994-03-14

Publications (2)

Publication Number Publication Date
ES2173953T3 true ES2173953T3 (es) 2002-11-01
ES2173953T5 ES2173953T5 (es) 2007-03-01

Family

ID=22791827

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95912666T Expired - Lifetime ES2173953T5 (es) 1994-03-14 1995-03-07 Uso del il-12 y antagonistas del il-12 para la fabricacion de una composicion farmaceutica para el tratamiento de enfermedades autoinmunes.

Country Status (14)

Country Link
US (1) US6338848B1 (es)
EP (4) EP2201959A3 (es)
JP (1) JP3798426B2 (es)
AT (1) ATE217533T1 (es)
AU (1) AU689236B2 (es)
CA (1) CA2185565C (es)
DE (1) DE69526728T3 (es)
DK (1) DK0750509T4 (es)
ES (1) ES2173953T5 (es)
IL (1) IL112677A (es)
PT (1) PT750509E (es)
TW (1) TW400233B (es)
WO (1) WO1995024918A1 (es)
ZA (1) ZA95960B (es)

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JP5646457B2 (ja) 2008-04-29 2014-12-24 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリン及びその使用
EP3002299A1 (en) 2008-06-03 2016-04-06 AbbVie Inc. Dual variable domain immunoglobulins and uses thereof
PE20100054A1 (es) 2008-06-03 2010-03-03 Abbott Lab Inmunoglobulina con dominio variable dual
MX2010014574A (es) 2008-07-08 2011-04-27 Abbott Lab Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
US20110243938A1 (en) * 2008-09-30 2011-10-06 Baylor Research Intitute Methods to Reduce B-Helper T Cells to Treat Autoimmune Diseases
MX2011005672A (es) * 2008-11-28 2011-06-20 Abbott Lab Composiciones de anticuerpo estables y metodos para estabilizar a las mismas.
AR078254A1 (es) 2009-09-01 2011-10-26 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
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MX2012004415A (es) 2009-10-15 2012-05-08 Abbott Lab Inmunoglobulinas de dominio variable doble y usos de las mismas.
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Also Published As

Publication number Publication date
AU689236B2 (en) 1998-03-26
EP1179348A2 (en) 2002-02-13
EP2311484A1 (en) 2011-04-20
TW400233B (en) 2000-08-01
WO1995024918A1 (en) 1995-09-21
PT750509E (pt) 2002-08-30
EP1179348A3 (en) 2003-12-03
AU1974995A (en) 1995-10-03
DE69526728T3 (de) 2007-01-04
DK0750509T3 (da) 2002-07-08
CA2185565C (en) 2009-02-03
DE69526728D1 (de) 2002-06-20
EP0750509B1 (en) 2002-05-15
DE69526728T2 (de) 2002-11-21
ES2173953T5 (es) 2007-03-01
DK0750509T4 (da) 2006-10-16
JPH09510444A (ja) 1997-10-21
EP0750509A1 (en) 1997-01-02
EP0750509B2 (en) 2006-06-14
IL112677A0 (en) 1995-05-26
CA2185565A1 (en) 1995-09-21
JP3798426B2 (ja) 2006-07-19
EP2201959A3 (en) 2011-03-16
US6338848B1 (en) 2002-01-15
ATE217533T1 (de) 2002-06-15
ZA95960B (en) 1995-10-10
IL112677A (en) 2000-01-31
EP2201959A2 (en) 2010-06-30

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