ES2174945T3 - Toxina de botulinum para la reduccion de cefaleas de migrañas. - Google Patents

Toxina de botulinum para la reduccion de cefaleas de migrañas.

Info

Publication number
ES2174945T3
ES2174945T3 ES95918353T ES95918353T ES2174945T3 ES 2174945 T3 ES2174945 T3 ES 2174945T3 ES 95918353 T ES95918353 T ES 95918353T ES 95918353 T ES95918353 T ES 95918353T ES 2174945 T3 ES2174945 T3 ES 2174945T3
Authority
ES
Spain
Prior art keywords
migraine
heads
reduction
botulinum toxin
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95918353T
Other languages
English (en)
Inventor
William J Binder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26933871&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2174945(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2174945T3 publication Critical patent/ES2174945T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

ESTA INVENCION ES UN METODO PARA REDUCIR EL DOLOR DE CABEZA Y LOS SINTOMAS ASOCIADOS CON LA APARICION DEL DOLOR DE CABEZA EN MAMIFEROS. EL METODO SE LLEVA A CABO LIBERANDO UNA NEUROTOXINA PRESINAPTICA INVERTEBRADA A UN MAMIFERO DE FORMA EXTRAMUSCULAR (PREFERIBLEMENTE EN EL LUGAR DEL DOLOR, DE FORMA LOCALIZADA), O EN UN LUGAR DE UNO O MAS MUSCULOS (PREFERIBLEMENTE LOS MUSCULOS DE LA CARA, CRANEO Y CUELLO). LAS NEUROTOXINAS ADMINISTRADAS DE ACUERDO CON ESTA INVENCION SON AQUELLAS NEUROTOXINAS CONOCIDAS POR PRODUCIR UNA PARALISIS FLACIDA Y REVERSIBLE DEL TEJIDO MUSCULAR EN LOS MAMIFEROS. LA NEUROTOXINA PREFERIDA PARA USAR EN ESTE METODO ES LA TOXINA BOTULINICA, ESPECIALMENTE LA TOXINA BOTULINICA A.
ES95918353T 1994-05-09 1995-05-02 Toxina de botulinum para la reduccion de cefaleas de migrañas. Expired - Lifetime ES2174945T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24097394A 1994-05-09 1994-05-09
US34333194A 1994-11-21 1994-11-21

Publications (1)

Publication Number Publication Date
ES2174945T3 true ES2174945T3 (es) 2002-11-16

Family

ID=26933871

Family Applications (2)

Application Number Title Priority Date Filing Date
ES00204206T Expired - Lifetime ES2238969T3 (es) 1994-05-09 1995-05-02 Neurotoxinas presinapticas para el tratamiento de cefaleas migrañosas.
ES95918353T Expired - Lifetime ES2174945T3 (es) 1994-05-09 1995-05-02 Toxina de botulinum para la reduccion de cefaleas de migrañas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES00204206T Expired - Lifetime ES2238969T3 (es) 1994-05-09 1995-05-02 Neurotoxinas presinapticas para el tratamiento de cefaleas migrañosas.

Country Status (12)

Country Link
US (1) US5714468A (es)
EP (2) EP1086702B1 (es)
JP (1) JP3066079B2 (es)
AT (2) ATE215832T1 (es)
AU (1) AU2431995A (es)
CA (2) CA2190011C (es)
DE (2) DE69526340T2 (es)
DK (2) DK1086702T3 (es)
ES (2) ES2238969T3 (es)
LU (1) LU92052I2 (es)
PT (2) PT1086702E (es)
WO (1) WO1995030431A1 (es)

Families Citing this family (179)

* Cited by examiner, † Cited by third party
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EP0758900A4 (en) 1997-05-21
DE69534150D1 (de) 2005-05-19
CA2312047A1 (en) 1995-11-16
ATE215832T1 (de) 2002-04-15
EP0758900B1 (en) 2002-04-10
PT1086702E (pt) 2005-08-31
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JPH10500406A (ja) 1998-01-13
DK0758900T3 (da) 2002-07-29
CA2190011C (en) 2000-09-26
PT758900E (pt) 2002-09-30
EP0758900A1 (en) 1997-02-26
ES2238969T3 (es) 2005-09-16
EP1086702A3 (en) 2001-04-04
EP1086702B1 (en) 2005-04-13
LU92052I2 (fr) 2013-04-03
DE69534150T2 (de) 2006-02-16
JP3066079B2 (ja) 2000-07-17
DK1086702T3 (da) 2005-05-23
DE69526340D1 (de) 2002-05-16
EP1086702A2 (en) 2001-03-28
ATE292977T1 (de) 2005-04-15
AU2431995A (en) 1995-11-29
US5714468A (en) 1998-02-03

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