ES2175330T3 - Complejos de terpiridina-platino(ii). - Google Patents

Complejos de terpiridina-platino(ii).

Info

Publication number
ES2175330T3
ES2175330T3 ES97901187T ES97901187T ES2175330T3 ES 2175330 T3 ES2175330 T3 ES 2175330T3 ES 97901187 T ES97901187 T ES 97901187T ES 97901187 T ES97901187 T ES 97901187T ES 2175330 T3 ES2175330 T3 ES 2175330T3
Authority
ES
Spain
Prior art keywords
complex
platino
terpiridina
activity
terpiridinplatino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97901187T
Other languages
English (en)
Inventor
Gordon Lowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Application granted granted Critical
Publication of ES2175330T3 publication Critical patent/ES2175330T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)

Abstract

UNA NUEVA CLASE DE COMPLEJOS 2,2 :6 ,2" - TERPIRIDINPLATINO(II) Y 2,2 :6 ,2" - TERPIRIDIN-PLATINO(II) SUSTITUIDOS EN LOS CUALES UN N- U O- O HALOGENO NUCLEOFILO ES EL CUARTO LIGANDO DEL PLATINO. LOS COMPUESTOS SON POTENTES INTERCALADORES DE ADN. ALGUNOS TIENEN ACTIVIDAD ANTITUMORAL. ALGUNOS TIENEN ACTIVIDAD ANTIPARASITARIA. UN NUEVO METODO PARA LA PREPARACION DE LOS COMPLEJOS IMPLICA LA REACCION DE UN COMPLEJO DE PT DE 1,5 - CICLOOCTADIENO CON UNA 2,2 :6 ,2" - TERPIRIDINA.
ES97901187T 1996-01-26 1997-01-24 Complejos de terpiridina-platino(ii). Expired - Lifetime ES2175330T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9601603.5A GB9601603D0 (en) 1996-01-26 1996-01-26 Terpyridine-platinum (II) complexes

Publications (1)

Publication Number Publication Date
ES2175330T3 true ES2175330T3 (es) 2002-11-16

Family

ID=10787628

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97901187T Expired - Lifetime ES2175330T3 (es) 1996-01-26 1997-01-24 Complejos de terpiridina-platino(ii).

Country Status (10)

Country Link
US (1) US20020013306A1 (es)
EP (2) EP0885233B1 (es)
JP (1) JP2000503982A (es)
AT (1) ATE219493T1 (es)
CA (1) CA2241992A1 (es)
DE (1) DE69713491T2 (es)
DK (1) DK0885233T3 (es)
ES (1) ES2175330T3 (es)
GB (1) GB9601603D0 (es)
WO (1) WO1997027202A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901253D0 (en) * 1999-01-20 1999-03-10 Isis Innovation Bis-terpyridine-platinum(II) complexes
JP2000332801A (ja) * 1999-05-19 2000-11-30 Matsushita Electric Ind Co Ltd 仮想avネットワーク構築装置、及び仮想avネットワーク構築方法、並びに仮想avネットワーク構築方法に関するプログラムを記載した記録媒体
US6774082B2 (en) * 2001-05-11 2004-08-10 Ibc Advanced Technologies, Inc. Compositions for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences
JP4186532B2 (ja) * 2002-07-12 2008-11-26 株式会社島津製作所 新規な金属錯体、及びそれを用いるタンパク質のアミノ酸配列決定方法
CN100523121C (zh) 2003-05-09 2009-08-05 富士胶片株式会社 有机电致发光装置和铂化合物
EP2924094B1 (en) 2003-06-02 2017-04-05 UDC Ireland Limited Organic electroluminescent devices and metal complex compounds
JP4500735B2 (ja) * 2004-09-22 2010-07-14 富士フイルム株式会社 有機電界発光素子
JP4531509B2 (ja) * 2004-09-27 2010-08-25 富士フイルム株式会社 発光素子
EP1669760A1 (en) * 2004-12-08 2006-06-14 Kreatech Biotechnology B.V. Labeled transition metal complexes
US7771845B2 (en) * 2005-03-14 2010-08-10 Fujifilm Corporation Organic electroluminescent device
EP2004177B1 (en) * 2006-03-16 2012-01-25 Women and Infants Hospital of Rhode Island Inc. Nitrofuran compounds for the treatment of cancer and angiogenesis
KR101438036B1 (ko) * 2006-09-29 2014-09-04 씨아이피엘에이 엘티디. 테모졸로미드 및 유사체의 개선된 제조방법
KR101548382B1 (ko) 2007-09-14 2015-08-28 유디씨 아일랜드 리미티드 유기 전계 발광 소자
JP4531836B2 (ja) * 2008-04-22 2010-08-25 富士フイルム株式会社 有機電界発光素子並びに新規な白金錯体化合物及びその配位子となり得る新規化合物
JP4531842B2 (ja) * 2008-04-24 2010-08-25 富士フイルム株式会社 有機電界発光素子
CN103492363B (zh) 2011-04-27 2016-08-24 日本瑞翁株式会社 聚合性化合物、聚合性组合物、高分子以及光学各向异性体
TW201609651A (zh) * 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程(一)
JP2017048115A (ja) 2014-01-09 2017-03-09 国立研究開発法人理化学研究所 抗マラリア薬
US10292976B2 (en) 2014-01-09 2019-05-21 Riken Anti-malarial agent
US10137119B2 (en) 2014-01-09 2018-11-27 Riken Anti-malarial agent
WO2017106500A1 (en) * 2015-12-15 2017-06-22 Respiratory Motion, Inc. Evaluation of respiratory volume monitoring to detect respiratory compromise before pulse oximetry and eliminate false desaturation alarms
AU2017347853B2 (en) 2016-10-27 2022-02-17 Celgene Quanticel Research, Inc. Bromodomain and extra-terminal protein inhibitor combination therapy
GB2611043A (en) * 2021-09-22 2023-03-29 Univ Dublin City A cis-platinum(II)-oligomer hybrid
CN116003478B (zh) * 2022-12-30 2025-06-06 中国药科大学 一类含有鸟嘌呤衍生物配体的三联吡啶-铂(ii)新型配合物及其制备方法和应用
CN118994258B (zh) * 2024-09-09 2025-09-26 山东海化集团有限公司 一种n^n^n型三联吡啶铂配合物及其制备方法和应用
CN121164259B (zh) * 2025-11-21 2026-02-03 四川工商职业技术学院 一种基于荧光传感器的检测系统及其制备方法和应用

Also Published As

Publication number Publication date
GB9601603D0 (en) 1996-03-27
DE69713491D1 (de) 2002-07-25
WO1997027202A1 (en) 1997-07-31
CA2241992A1 (en) 1997-07-31
EP1164138A1 (en) 2001-12-19
US20020013306A1 (en) 2002-01-31
DK0885233T3 (da) 2002-07-15
EP0885233B1 (en) 2002-06-19
JP2000503982A (ja) 2000-04-04
ATE219493T1 (de) 2002-07-15
EP0885233A1 (en) 1998-12-23
DE69713491T2 (de) 2002-10-02

Similar Documents

Publication Publication Date Title
ES2175330T3 (es) Complejos de terpiridina-platino(ii).
ATE252639T1 (de) Modifizierter, das dorsalgewebe beeinflussender faktor
DK1482042T3 (da) Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren
EP1131333A4 (en) INSULATED NUCLEIC ACID MOLECULES ENCODING INDUCIBLE FACTORS DERIVED FROM T-CELL (TIF), ENCODED PROTEINS AND USE THEREOF
DK272388D0 (da) Vipbar understoetning til stole, saeder og lignende
NO911694D0 (no) Mikroemulsjonsblanding til haarbehandling, fremgangsmaate for fremstilling og anvendelse derav.
TR200100056T2 (tr) Nörotrofik faktörler
DE3852412D1 (de) Struktur, geeignet für die Verwendung in festen elektrochemischen Elementen.
DK122687D0 (da) Polypeptid, dna og anvendelse deraf
BR9808646A (pt) Sequenciador de gene e processos
IS4902A (is) Stilliefni fyrir endurmyndun vefja
DK486587A (da) Gen, kodende for humane kolonistimulerende faktorer
EP0585257A4 (en) DNA AND AMINO ACID SEQUENCE SPECIFIC TO NATURAL K KILLER CELLS.
NO891818L (no) T4-reseptor-protein, relaterte dna-sekvenser samt fremstilling derav.
NO865068D0 (no) System, fremgangsmaate og apparat til fraksjonering av blod in situ.
DK317288D0 (da) Hybridprotein af humant protein c og dets fremstilling samt dna, som koder det
DE3861642D1 (de) Katalysator zur wasserstoffbehandlung von kohlenwasserstoffen und methode zu dessen herstellung.
NO910982L (no) Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
DK0393502T3 (da) Opløselige interferon-gamma-receptorer og fremgangsmåder til fremstilling heraf
FI863626A7 (fi) DNA-sekvenssejä, yhdistelmä-DNA -molekyylejä ja menetelmiä ihmisen lip okortiinin kaltaisia polypeptidejä.
NO993653D0 (no) Fremgangsmåte for diagnose, prognose og behandling av glaukom og relaterte sykdommer
DK0643719T3 (da) Nukleinsyresekvenser, som koder for eller er komplementære til nukleinsyresekvenser, som koder for interleukin 9-receptor
PE20399A1 (es) Muteina ob
DK151788D0 (da) Hybridserpiner og dna, som koder derfor
DE69530295D1 (de) Leishmania hauptprotein, dafür kodierende nukleinsaüre und verwendungen davon

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 885233

Country of ref document: ES