ES2175676T3 - Sistema terapeutico expansible de retencion gastrica con liberacion controlada de principio activo en el tracto gastrointestinal. - Google Patents

Sistema terapeutico expansible de retencion gastrica con liberacion controlada de principio activo en el tracto gastrointestinal.

Info

Publication number
ES2175676T3
ES2175676T3 ES98906865T ES98906865T ES2175676T3 ES 2175676 T3 ES2175676 T3 ES 2175676T3 ES 98906865 T ES98906865 T ES 98906865T ES 98906865 T ES98906865 T ES 98906865T ES 2175676 T3 ES2175676 T3 ES 2175676T3
Authority
ES
Spain
Prior art keywords
controlled release
expansible
gastrointestinal tract
active principle
therapeutic system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98906865T
Other languages
English (en)
Inventor
Bodo Asmussen
Karsten Cremer
Hans-Rainer Hoffmann
Karin Ludwig
Michael Roreger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2175676T3 publication Critical patent/ES2175676T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Wood Science & Technology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UN DISPOSITIVO PARA LA LIBERACION CONTROLADA DE SUSTANCIAS ACTIVAS EN EL TRACTO GASTRO - INTESTINAL, CON PASO RETARDADO A TRAVES DEL PILORO, COMPRENDIENDO EL DISPOSITIVO UN COMPONENTE QUE PUEDE DILATARSE EN CONTACTO CON EL JUGO GASTRICO, Y VA RODEADO POR UNA ENVOLTURA POLIMERICA QUE ES PERMEABLE AL JUGO GASTRICO Y A LAS SUSTANCIAS ACTIVAS. EL DISPOSITIVO COMPRENDE AL MENOS UNA SUSTANCIA ACTIVA EN FORMA DE UN PREPARADO DE PARTICULAS MULTIPLES QUE LIBERA LA SUSTANCIA ACTIVA EN EL JUGO GASTRICO DE MANERA RETARDADA. LA LIBERACION DE SUSTANCIA ACTIVA A PARTIR DE UN DISPOSITIVO SEGUN LA INVENCION PUEDE CONTROLARSE MEJOR QUE EN LOS MEDICAMENTOS CONVENCIONALES, CON UN PASO RETARDADO A TRAVES DEL PILORO. DE LA MISMA MANERA, EL DISPOSITIVO PUEDE ENROLLARSE O PLEGARSE FACILMENTE, INSERTANDOSE SIN DIFICULTAD ALGUNA EN EL INTERIOR DE CAPSULAS.
ES98906865T 1997-01-14 1998-01-09 Sistema terapeutico expansible de retencion gastrica con liberacion controlada de principio activo en el tracto gastrointestinal. Expired - Lifetime ES2175676T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19700915 1997-01-14

Publications (1)

Publication Number Publication Date
ES2175676T3 true ES2175676T3 (es) 2002-11-16

Family

ID=7817288

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98906865T Expired - Lifetime ES2175676T3 (es) 1997-01-14 1998-01-09 Sistema terapeutico expansible de retencion gastrica con liberacion controlada de principio activo en el tracto gastrointestinal.

Country Status (20)

Country Link
US (1) US6290989B1 (es)
EP (1) EP0961611B1 (es)
JP (1) JP3825811B2 (es)
KR (1) KR100503266B1 (es)
AT (1) ATE214916T1 (es)
AU (1) AU727753B2 (es)
CA (1) CA2277277C (es)
CZ (1) CZ297098B6 (es)
DE (2) DE19800523C2 (es)
DK (1) DK0961611T3 (es)
ES (1) ES2175676T3 (es)
HU (1) HU224224B1 (es)
ID (1) ID22698A (es)
IL (1) IL130872A (es)
NO (1) NO993383L (es)
NZ (1) NZ336691A (es)
PL (1) PL193282B1 (es)
PT (1) PT961611E (es)
SK (1) SK93999A3 (es)
WO (1) WO1998031341A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19822278A1 (de) * 1998-05-18 1999-12-02 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage
DE19837073A1 (de) * 1998-08-17 2000-03-23 Lohmann Therapie Syst Lts Folienförmige Wirkstoffträger
DE19849848A1 (de) * 1998-10-29 2000-05-04 Lohmann Therapie Syst Lts Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung
DE19850309A1 (de) * 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
DE19920854A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Verfahren und Vorrichtung zum Herstellen eines gastroretentiven flachen Schlauchbeutels mit Längsnaht
DE19920837A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System für verlängerte Verweilzeit im Magen bzw. im Gastrointestinaltrakt
DE19920855A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Magenvolumenreduzierende Darreichungsform
DE19920833A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit quellbaren Polymeren
DE19920838A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit Kapillaren
ES2270982T3 (es) * 2000-02-04 2007-04-16 Depomed, Inc. Forma de dosificacion de nucleo y carcasa que se aproxima a una liberacion del farmaco de orden cero.
GB0102725D0 (en) * 2001-02-02 2001-03-21 Stowic Resources Ltd Medical delivery system
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
EP1487405A1 (de) * 2001-12-17 2004-12-22 Günther Beisel Mittel zur oralen einnahme und verfahren zu dessen herstellung
US6869333B2 (en) * 2002-09-11 2005-03-22 National Optronics, Inc. Lens blank alignment and blocking device and method
CA2501345A1 (en) * 2002-10-11 2004-04-22 Depomed Development, Ltd. Gastro-retentive levodopa delivery form
TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
WO2006010635A2 (en) * 2004-07-30 2006-02-02 Merrion Research Ii Limited Improved process and machine for automated manufacture of gastro-retentive devices
US8852083B2 (en) * 2005-02-04 2014-10-07 Uti Limited Partnership Self-stabilized encapsulated imaging system
KR100822519B1 (ko) * 2005-02-15 2008-04-16 주식회사종근당 위장 내에서 제어방출되는 단일 매트릭스 정제
WO2007084818A2 (en) * 2006-01-10 2007-07-26 Pipex, Inc. Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
AU2007231510A1 (en) * 2006-03-29 2007-10-04 Electronic Dietary Foods Inc. Ingestible implement for weight control
US9579227B2 (en) * 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
CA2672602C (en) * 2006-12-18 2014-05-20 Electronic Dietary Foods Inc. Device for delivery of a substance
US20080286343A1 (en) * 2007-05-16 2008-11-20 Dzenana Cengic Solid form
US20120321706A1 (en) * 2009-10-19 2012-12-20 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
US20140343452A1 (en) * 2011-12-21 2014-11-20 Eatlittle Inc. Pseudobezoar-Based Intraluminal Gastrointestinal Cleansing and Biospy
US11529310B2 (en) 2020-12-08 2022-12-20 Ruminant Biotech Corp Limited Devices and methods for delivery of substances to animals

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
DE3400106A1 (de) * 1984-01-04 1985-07-11 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung
AU6541786A (en) * 1985-10-09 1987-05-05 Desitin Arzneimittel Gmbh Process for producing an administration or dosage form of drugs, reagents or other active ingredients
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
EP0408496A3 (en) * 1989-07-12 1992-07-01 Ciba-Geigy Ag Solid dosage form for pharmaceutical substances
WO1993012765A1 (en) * 1991-12-27 1993-07-08 Merck & Co., Inc. A controlled release drug dispersion delivery device
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
US5260069A (en) * 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen

Also Published As

Publication number Publication date
JP3825811B2 (ja) 2006-09-27
CA2277277C (en) 2005-03-08
NZ336691A (en) 2000-05-26
PL334834A1 (en) 2000-03-27
CA2277277A1 (en) 1998-07-23
HUP0000943A3 (en) 2000-11-28
PT961611E (pt) 2002-09-30
NO993383D0 (no) 1999-07-08
CZ249599A3 (cs) 2000-01-12
NO993383L (no) 1999-07-08
KR100503266B1 (ko) 2005-07-25
EP0961611A2 (de) 1999-12-08
IL130872A (en) 2004-02-19
ID22698A (id) 1999-12-09
SK93999A3 (en) 2000-01-18
PL193282B1 (pl) 2007-01-31
EP0961611B1 (de) 2002-03-27
WO1998031341A1 (de) 1998-07-23
ATE214916T1 (de) 2002-04-15
HU224224B1 (hu) 2005-06-28
DE59803511D1 (de) 2002-05-02
KR20000070179A (ko) 2000-11-25
DK0961611T3 (da) 2002-07-15
HUP0000943A2 (hu) 2000-10-28
DE19800523A1 (de) 1998-07-30
AU727753B2 (en) 2000-12-21
CZ297098B6 (cs) 2006-09-13
IL130872A0 (en) 2001-01-28
AU6292298A (en) 1998-08-07
US6290989B1 (en) 2001-09-18
DE19800523C2 (de) 1999-01-21
JP2001508068A (ja) 2001-06-19

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