ES2178943B1 - Uso de compuestos organicos en el tratamiento de enfermedad pulmonar obstructiva cronica. - Google Patents

Uso de compuestos organicos en el tratamiento de enfermedad pulmonar obstructiva cronica.

Info

Publication number
ES2178943B1
ES2178943B1 ES200002868A ES200002868A ES2178943B1 ES 2178943 B1 ES2178943 B1 ES 2178943B1 ES 200002868 A ES200002868 A ES 200002868A ES 200002868 A ES200002868 A ES 200002868A ES 2178943 B1 ES2178943 B1 ES 2178943B1
Authority
ES
Spain
Prior art keywords
treatment
pulmonary disease
chronic obstructive
obstructive pulmonary
organic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200002868A
Other languages
English (en)
Other versions
ES2178943A1 (es
Inventor
Barbara Haeberlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10865451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2178943(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of ES2178943A1 publication Critical patent/ES2178943A1/es
Application granted granted Critical
Publication of ES2178943B1 publication Critical patent/ES2178943B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Uso de compuestos orgánicos en el tratamiento de enfermedad pulmonar obstructiva crónica, en particular uso de un polvo seco que comprende (A) formoterol o una sal o solvato del mismo farmacéuticamente aceptable, o un solvato de dicha sal, y (B) un diluyente o vehículo en partículas, farmacéuticamente aceptable, en una cantidad de 400 {mi}g a 5.OOO {mi}g por {mi}g de (A), en la preparación de un medicamento inhalable para el tratamiento de la enfermedad pulmonar obstructiva crónica.
ES200002868A 1999-11-30 2000-11-30 Uso de compuestos organicos en el tratamiento de enfermedad pulmonar obstructiva cronica. Expired - Fee Related ES2178943B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9928311.1A GB9928311D0 (en) 1999-11-30 1999-11-30 Organic compounds

Publications (2)

Publication Number Publication Date
ES2178943A1 ES2178943A1 (es) 2003-01-01
ES2178943B1 true ES2178943B1 (es) 2004-03-16

Family

ID=10865451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200002868A Expired - Fee Related ES2178943B1 (es) 1999-11-30 2000-11-30 Uso de compuestos organicos en el tratamiento de enfermedad pulmonar obstructiva cronica.

Country Status (24)

Country Link
US (3) US6887459B1 (es)
EP (3) EP3050558A1 (es)
JP (3) JP2003515551A (es)
KR (1) KR100771281B1 (es)
CN (1) CN1399540A (es)
AU (1) AU769765B2 (es)
BR (1) BR0015908A (es)
CA (1) CA2389349C (es)
CZ (1) CZ20021850A3 (es)
ES (1) ES2178943B1 (es)
FR (1) FR2801506B1 (es)
GB (1) GB9928311D0 (es)
HU (1) HUP0203728A3 (es)
IL (2) IL149362A0 (es)
IT (1) ITMI20002556A1 (es)
MX (1) MXPA02005384A (es)
NO (1) NO20021963D0 (es)
NZ (1) NZ518873A (es)
PL (1) PL354974A1 (es)
RU (1) RU2327452C2 (es)
SK (1) SK7432002A3 (es)
TW (1) TWI278324B (es)
WO (1) WO2001039745A2 (es)
ZA (1) ZA200204147B (es)

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PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
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CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
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EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
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Also Published As

Publication number Publication date
WO2001039745A3 (en) 2001-12-20
BR0015908A (pt) 2002-08-06
ES2178943A1 (es) 2003-01-01
IL149362A (en) 2015-06-30
KR100771281B1 (ko) 2007-10-29
RU2002116251A (ru) 2004-01-20
EP2011484A3 (en) 2009-01-14
US20050136010A1 (en) 2005-06-23
NO20021963L (no) 2002-04-25
KR20020058050A (ko) 2002-07-12
CZ20021850A3 (cs) 2002-08-14
CN1399540A (zh) 2003-02-26
EP1233757A2 (en) 2002-08-28
CA2389349C (en) 2009-10-20
US20070196286A1 (en) 2007-08-23
GB9928311D0 (en) 2000-01-26
AU769765B2 (en) 2004-02-05
MXPA02005384A (es) 2002-11-29
FR2801506A1 (fr) 2001-06-01
TWI278324B (en) 2007-04-11
PL354974A1 (en) 2004-03-22
RU2327452C2 (ru) 2008-06-27
JP2013075909A (ja) 2013-04-25
JP2015108020A (ja) 2015-06-11
HUP0203728A3 (en) 2003-12-29
EP3050558A1 (en) 2016-08-03
US6887459B1 (en) 2005-05-03
AU2837401A (en) 2001-06-12
JP2003515551A (ja) 2003-05-07
ITMI20002556A1 (it) 2002-05-28
FR2801506B1 (fr) 2002-12-27
CA2389349A1 (en) 2001-06-07
NO20021963D0 (no) 2002-04-25
IL149362A0 (en) 2002-11-10
SK7432002A3 (en) 2002-10-08
EP2011484A2 (en) 2009-01-07
HUP0203728A2 (hu) 2003-03-28
WO2001039745A2 (en) 2001-06-07
ZA200204147B (en) 2003-01-29
NZ518873A (en) 2004-02-27

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