ES2179079T3 - Comprimidos que contienen granulos entericos. - Google Patents

Comprimidos que contienen granulos entericos.

Info

Publication number
ES2179079T3
ES2179079T3 ES94929012T ES94929012T ES2179079T3 ES 2179079 T3 ES2179079 T3 ES 2179079T3 ES 94929012 T ES94929012 T ES 94929012T ES 94929012 T ES94929012 T ES 94929012T ES 2179079 T3 ES2179079 T3 ES 2179079T3
Authority
ES
Spain
Prior art keywords
granules
tablet
enteric
tableting
reduced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929012T
Other languages
English (en)
Inventor
Tomohisa Matsushita
Mitsuo Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Application granted granted Critical
Publication of ES2179079T3 publication Critical patent/ES2179079T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

TABLETA QUE CONTIENE GRANULOS ENTERICOS PREPARADAS FORMANDO TABLETAS A PARTIR DE UNA MEZCLA DE GRANULOS ENTERICOS, QUE CONTIENEN UNA BASE CON AL MENOS UN MIEMBRO SELECCIONADO DEL GRUPO QUE SE COMPONE DE HITROTALCITA SINTETICA, GEL DE HIDROXIDO ALUMINICO SECO, UN COPRECIPITADO DE HIDROXIDO ALUMINICO CON HIDROCARBONATO SODICO, HIDROXIDO DE MAGNESIO ALUMINICO, SILICATO ALUMINICO SINTETICO Y AMINOACETATO DE DIHIDROXIALUMINIO. CUANDO SE COMPARA CON LA TABLETAS CONVENCIONALES, ESTA TABLETA TIENE LAS SIGUIENTES VENTAJAS: EL CONTENIDO DE GRANULOS ENTERICOS SE AUMENTA MEDIANTE EL USO DE UN RELLENO ESPECIFICO; LA BASE SE DISPERSA RAPIDAMENTE EN LOS GRANULOS; LOS GRANULOS TIENEN UNA CAPACIDAD DE LIBERACION DEL MEDICAMENTO Y UNA RESISTENCIA ACIDA COMPARABLE A LA QUE TENIAN ANTES DE LA ELABORACION DE LA TABLETA: EL DAÑO AL RECUBRIMIENTO SE REDUCE; LA VARIACION EN EL PESO DURANTE LA ELABORACION DE TABLETAS SE REDUCE; Y LA TABLETA TIENE UNA ELEVADA CONCENTRACION . LA TECNICA DE PREPARACION DE UNA TABLETAQUE TENGA UN CONTENIDO DE GRANULOS ENTERICOS ELEVADO TIENE LAS VENTAJAS DE UNA ADMINISTRABILIDAD MEJORADA DEBIDA AL TAMAÑO REDUCIDO DE LA TABLETA Y A LA APLICABILIDAD A OTROS MEDICAMENTOS.
ES94929012T 1993-10-12 1994-10-06 Comprimidos que contienen granulos entericos. Expired - Lifetime ES2179079T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25404993 1993-10-12

Publications (1)

Publication Number Publication Date
ES2179079T3 true ES2179079T3 (es) 2003-01-16

Family

ID=17259525

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929012T Expired - Lifetime ES2179079T3 (es) 1993-10-12 1994-10-06 Comprimidos que contienen granulos entericos.

Country Status (12)

Country Link
US (1) US5798120A (es)
EP (1) EP0723777B1 (es)
JP (1) JP3710473B2 (es)
KR (1) KR100353384B1 (es)
AT (1) ATE219931T1 (es)
AU (1) AU683092B2 (es)
CA (1) CA2173506C (es)
DE (1) DE69430921T2 (es)
DK (1) DK0723777T3 (es)
ES (1) ES2179079T3 (es)
PT (1) PT723777E (es)
WO (1) WO1995010264A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9600857A (es) * 1994-07-08 1997-06-28 Astra Ab Forma de dosificacion i en tabletas, con unidades multiples.
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9600072D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
WO1998023272A1 (en) * 1996-11-27 1998-06-04 The Procter & Gamble Company Compositions and methods for the treatment of gastrointestinal disorders
JP3870470B2 (ja) * 1997-02-07 2007-01-17 大正製薬株式会社 マルチプルユニットタイプ徐放性錠剤
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
KR20010034770A (ko) 1998-04-17 2001-04-25 우에하라 아끼라 멀티플 유닛 타입 서방성 정제
AU3731699A (en) 1998-05-18 1999-12-06 Takeda Chemical Industries Ltd. Orally disintegrable tablets
AU4802099A (en) * 1998-07-28 2000-02-21 Takeda Chemical Industries Ltd. Rapidly disintegrable solid preparation
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
WO2004073654A2 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
KR20050123096A (ko) * 2003-02-24 2005-12-29 미쯔비시 웰 파마 가부시키가이샤 테나토프라졸의 거울상 이성질체 및 치료를 위한 그 용도
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7670624B2 (en) * 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
SI2007362T1 (sl) 2006-04-04 2018-12-31 Kg Acquisition Llc Peroralne odmerne oblike, ki vključujejo antitrombocitno sredstvo in inhibitor kisline
EP2026768B1 (en) * 2006-06-01 2018-02-28 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
JP5041774B2 (ja) * 2006-09-22 2012-10-03 日本ケミファ株式会社 メサラジンを有効成分として含有する徐放性錠剤
JP4329947B1 (ja) * 2009-01-20 2009-09-09 ライオン株式会社 内服用錠剤
CN102198131A (zh) * 2010-03-24 2011-09-28 济南瑞安药业发展有限公司 一种含有奥美拉唑的新的复方制剂
PE20140005A1 (es) * 2010-12-03 2014-01-23 Takeda Pharmaceutical Tableta oralmente desintegradora
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971486A (en) * 1960-04-01 1964-09-30 Rech S Pharma Et Scient Therapeutic compositions comprising aspirin and polysiloxanes
US4874614A (en) * 1985-03-25 1989-10-17 Abbott Laboratories Pharmaceutical tableting method
CA1259924A (en) * 1985-03-25 1989-09-26 Wallace E. Becker Pharmaceutical tableting method
CA1327010C (en) * 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
JPH0780754B2 (ja) * 1986-08-06 1995-08-30 エーザイ株式会社 多顆粒型持続性錠剤
JP2514078B2 (ja) * 1988-08-22 1996-07-10 エスエス製薬株式会社 圧縮成型製剤
JP2781442B2 (ja) * 1990-02-19 1998-07-30 旭化成工業株式会社 顆粒含有錠剤
JP2856485B2 (ja) * 1990-03-07 1999-02-10 旭化成工業株式会社 顆粒含有錠

Also Published As

Publication number Publication date
US5798120A (en) 1998-08-25
EP0723777A1 (en) 1996-07-31
EP0723777B1 (en) 2002-07-03
EP0723777A4 (en) 1997-06-25
JP3710473B2 (ja) 2005-10-26
AU683092B2 (en) 1997-10-30
DK0723777T3 (da) 2002-10-28
AU7822294A (en) 1995-05-04
KR960704531A (ko) 1996-10-09
ATE219931T1 (de) 2002-07-15
PT723777E (pt) 2002-11-29
DE69430921D1 (de) 2002-08-08
CA2173506A1 (en) 1995-04-20
CA2173506C (en) 2006-05-09
KR100353384B1 (ko) 2002-12-28
WO1995010264A1 (en) 1995-04-20
DE69430921T2 (de) 2003-02-13

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