ES2179606T3 - Polietileno con peso molecular ultra elevado (uhmw-pe) para implantes. - Google Patents

Polietileno con peso molecular ultra elevado (uhmw-pe) para implantes.

Info

Publication number
ES2179606T3
ES2179606T3 ES99810845T ES99810845T ES2179606T3 ES 2179606 T3 ES2179606 T3 ES 2179606T3 ES 99810845 T ES99810845 T ES 99810845T ES 99810845 T ES99810845 T ES 99810845T ES 2179606 T3 ES2179606 T3 ES 2179606T3
Authority
ES
Spain
Prior art keywords
implants
molecular weight
weight polyethylene
uhmw
ultra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99810845T
Other languages
English (en)
Inventor
Silvio Schaffner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer GmbH
Original Assignee
Zimmer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer GmbH filed Critical Zimmer GmbH
Application granted granted Critical
Publication of ES2179606T3 publication Critical patent/ES2179606T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2207/00—Properties characterising the ingredient of the composition
    • C08L2207/06—Properties of polyethylene
    • C08L2207/068—Ultra high molecular weight polyethylene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethylene

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)

Abstract

Procedimiento para la fabricación de un implante de polietileno de UHMW, donde en una primera etapa se mezcla polvo de partículas de polietileno de UHMW con un líquido, que contiene vitamina E en una cantidad predeterminada, en una segunda etapa, el líquido es evaporado y la vitamina E es acumulada en una concentración predeterminada de 0,1 % < k < 0,4 % sobre las partículas de polietileno, en una tercera etapa, las partículas de polietileno son prensadas a temperaturas en torno a 180 C 240 C y a presiones en torno a 2 10 MPa para formar bloques o son extruídas para formar barras, en una cuarta etapa, a partir de los bloques o barras se corta el implante en su forma definitiva a través de conformación por arranque de virutas, en una quinta etapa, el implante es encerrado en una atmósfera de gas protector en una envoltura y es expuesto durante una esterilización gamma a una radiación de al menos 2,5 Mrad.
ES99810845T 1998-10-21 1999-09-22 Polietileno con peso molecular ultra elevado (uhmw-pe) para implantes. Expired - Lifetime ES2179606T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98811048A EP0995449A1 (de) 1998-10-21 1998-10-21 UHMW-Polyethylen für Implantate

Publications (1)

Publication Number Publication Date
ES2179606T3 true ES2179606T3 (es) 2003-01-16

Family

ID=8236397

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99810845T Expired - Lifetime ES2179606T3 (es) 1998-10-21 1999-09-22 Polietileno con peso molecular ultra elevado (uhmw-pe) para implantes.

Country Status (6)

Country Link
US (1) US6277390B1 (es)
EP (1) EP0995449A1 (es)
JP (1) JP4970636B2 (es)
AT (1) ATE219692T1 (es)
DE (1) DE59901842D1 (es)
ES (1) ES2179606T3 (es)

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* Cited by examiner, † Cited by third party
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SE9900519D0 (sv) * 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
ATE418933T1 (de) 2000-04-27 2009-01-15 Orthopaedic Hospital Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung
US7431874B2 (en) * 2003-01-16 2008-10-07 Massachusetts General Hospital Methods for making oxidation resistant polymeric material
AT412969B (de) * 2003-05-19 2005-09-26 Klaus Dr Lederer Vernetztes, ultra-hochmolekulares polyethylen (uhmw-pe)
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
CA2565849C (en) * 2004-05-11 2013-01-29 The General Hospital Corporation Dba Massachusetts General Hospital Methods for making oxidation resistant polymeric material
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
WO2006138247A2 (en) * 2005-06-14 2006-12-28 Omni Life Science, Inc Crosslinked polyethylene article
ES2509884T3 (es) 2005-08-18 2014-10-20 Zimmer Gmbh Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ultra-alto
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070077268A1 (en) * 2005-09-30 2007-04-05 Depuy Products, Inc. Hydrophobic carrier modified implants for beneficial agent delivery
US8425614B2 (en) * 2006-03-20 2013-04-23 Biomet Manufacturing Corp. Modular center pegged glenoid
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
ATE481989T1 (de) 2006-08-25 2010-10-15 Depuy Products Inc Material zum tragen eines medizinischen implantats
AU2008207807B2 (en) * 2007-01-25 2013-05-16 Cambridge Polymer Group, Inc. Methods for making oxidation-resistant cross-linked polymeric materials
US20100190920A1 (en) * 2007-02-14 2010-07-29 Anuj Bellare Crosslinked polymers and methods of making the same
CA2681475A1 (en) * 2007-03-20 2008-09-25 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked uhmwpe
ES2378721T3 (es) * 2007-04-10 2012-04-17 Zimmer, Inc. Polietileno reticulado de peso molecular ultra alto estabilizado por antioxidantes para aplicaciones en dispositivos médicos
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
GB0707418D0 (en) * 2007-04-17 2007-05-23 Smith & Nephew Dental implants
EP2142353A1 (en) 2007-04-18 2010-01-13 Smith &amp; Nephew PLC Expansion moulding of shape memory polymers
AU2008243037A1 (en) * 2007-04-19 2008-10-30 Smith & Nephew, Inc. Knee and shoulder joint prosthesis
US8747976B2 (en) * 2007-04-19 2014-06-10 Smith & Nephew, Inc. Orientated polymeric devices
WO2008130954A2 (en) 2007-04-19 2008-10-30 Smith & Nephew, Inc. Graft fixation
JP5520814B2 (ja) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッド マルチモーダル形状記憶ポリマー
WO2008130989A2 (en) * 2007-04-19 2008-10-30 Smith & Nephew, Inc. Prosthetic implants
AU2008296237A1 (en) * 2007-09-04 2009-03-12 Smith & Nephew Orthopaedics Ag Ultra high molecular weight polyethylene for bearing surfaces
US8652212B2 (en) 2008-01-30 2014-02-18 Zimmer, Inc. Orthopedic component of low stiffness
US8586667B2 (en) 2008-05-13 2013-11-19 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked UHMWPE
JP5311457B2 (ja) * 2008-06-20 2013-10-09 ナカシマメディカル株式会社 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材
US20100022678A1 (en) * 2008-07-24 2010-01-28 Zimmer, Inc. Reduction of free radicals in crosslinked polyethylene by infrared heating
US8133436B2 (en) 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
US9745462B2 (en) * 2008-11-20 2017-08-29 Zimmer Gmbh Polyethylene materials
AU2009340512A1 (en) 2009-02-19 2011-09-01 Smith & Nephew Orthopaedics Ag Medical implant producing wear particles with benign body response
AU2010246119C1 (en) 2009-05-04 2017-05-18 Smith & Nephew, Inc. Synergistic effects of blending multiple additives in UHMWPE
JP2011173979A (ja) * 2010-02-24 2011-09-08 Nakashima Medical Co Ltd 超高分子量ポリエチレンの成形品
JP5765797B2 (ja) * 2010-02-24 2015-08-19 ナカシマメディカル株式会社 超高分子量ポリエチレンの成形品
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
US20130018476A1 (en) 2011-07-13 2013-01-17 Biomet Manufacturing Corp. Shoulder prosthesis
US8506638B2 (en) 2011-07-13 2013-08-13 Biomets Manufacturing, LLC Shoulder prosthesis
US9708467B2 (en) 2013-10-01 2017-07-18 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
US20170029597A1 (en) 2013-11-29 2017-02-02 Saudi Basic Industries Corporation Stabilised polyolefin composition
WO2015138137A1 (en) 2014-03-12 2015-09-17 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
WO2016090084A1 (en) 2014-12-03 2016-06-09 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
CZ2015267A3 (cs) 2015-04-21 2016-11-09 Ústav makromolekulární chemie AV ČR, v. v. i. Směs pro stabilizaci polyethylenu, polyethylen a způsob jeho přípravy, polyethylenové implantáty
CN105837896A (zh) * 2016-04-20 2016-08-10 江南大学 一种超高分子量聚乙烯复合材料的制备方法
AU2021200854A1 (en) 2020-03-03 2021-09-16 Howmedica Osteonics Corp. Glenoid implant with additively manufactured fixation posts

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Publication number Priority date Publication date Assignee Title
CS221403B1 (cs) * 1981-12-23 1983-04-29 Bretislav Dolezel Způsob zdravotně nezávadné stabilizace polyolefinů proti termooxidační a fotooxidační degradaci
US5308549A (en) * 1991-11-12 1994-05-03 Hoffmann-La Roche Inc. Stabilizers for thermo plastic materials
DE4306593A1 (de) * 1993-03-03 1994-09-08 Hoechst Ag Stabilisierte Formmasse aus Polyethylen, ein Verfahren zur Herstellung und Verwendung
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
RU2211008C2 (ru) * 1996-02-13 2003-08-27 Массачусетс Институт Оф Текнолоджи Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением

Also Published As

Publication number Publication date
ATE219692T1 (de) 2002-07-15
JP2000126281A (ja) 2000-05-09
US6277390B1 (en) 2001-08-21
EP0995449A1 (de) 2000-04-26
DE59901842D1 (de) 2002-08-01
JP4970636B2 (ja) 2012-07-11

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