ES2179853T3 - Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos. - Google Patents

Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos.

Info

Publication number
ES2179853T3
ES2179853T3 ES95100632T ES95100632T ES2179853T3 ES 2179853 T3 ES2179853 T3 ES 2179853T3 ES 95100632 T ES95100632 T ES 95100632T ES 95100632 T ES95100632 T ES 95100632T ES 2179853 T3 ES2179853 T3 ES 2179853T3
Authority
ES
Spain
Prior art keywords
spr
gps
iii
binding
aoao
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95100632T
Other languages
English (en)
Inventor
Dr Peter Sluka
Dr Hans-Georg Batz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4435728A external-priority patent/DE4435728A1/de
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2179853T3 publication Critical patent/ES2179853T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A UNA MATRIZ DE AGLOMERANTE, CONTENIENDO UN MATERIAL PORTADOR CON UNA SUPERFICIE OXIDICA Y UN REACTIVO DE FASE SOLIDA LIGADO DE FORMA COVALENTE A TRAVES DE GRUPO DE ANCLAJE, QUE DISPONE DE CAPACIDAD DE AGLOMERACION CON AL MENOS UN PARTNER DE REACCION LIBRE, CARACTERIZANDOSE PORQUE EL REACTIVO DE FASE SOLIDA FORMA UNA CAPA DE AGLOMERANTE DILUIDA Y DE FORMA LATERAL ESENCIALMENTE HOMOGENEA EN LA SUPERFICIE DEL MATERIAL PORTADOR, DE MODO QUE LOS GRUPOS DE ANCLAJE SON GRUPOS SILANO Y SE UNEN CON EL REACTIVO DE FASE SOLIDA A TRAVES DE UNA MOLECULA ESPACIADORA.
ES95100632T 1994-01-19 1995-01-18 Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos. Expired - Lifetime ES2179853T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4401450 1994-01-19
DE4435728A DE4435728A1 (de) 1994-01-19 1994-10-06 Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix

Publications (1)

Publication Number Publication Date
ES2179853T3 true ES2179853T3 (es) 2003-02-01

Family

ID=25933130

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95100632T Expired - Lifetime ES2179853T3 (es) 1994-01-19 1995-01-18 Compuestos de biotina-silanos y matriz de fijacion que contiene estos compuestos.

Country Status (4)

Country Link
EP (1) EP0664452B1 (es)
JP (1) JP3214795B2 (es)
AT (1) ATE221660T1 (es)
ES (1) ES2179853T3 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472148B1 (en) 1994-09-26 2002-10-29 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
DE19715484A1 (de) * 1997-04-14 1998-10-15 Boehringer Mannheim Gmbh Verfahren zum Aufbringen von Reagenzspots
DE19748489A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
US7794946B1 (en) 1998-02-04 2010-09-14 Life Technologies Corporation Microarray and uses therefor
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6753143B2 (en) 2000-05-01 2004-06-22 Clinical Micro Sensors, Inc. Target analyte detection using asymmetrical self-assembled monolayers
US20040248323A1 (en) 2003-06-09 2004-12-09 Protometrix, Inc. Methods for conducting assays for enzyme activity on protein microarrays
DE102006038231A1 (de) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Implantat aus einem biokorrodierbaren metallischen Werkstoff mit einer Beschichtung aus einer Organosiliziumverbindung
FR2943344B1 (fr) * 2009-03-18 2011-04-15 Commissariat Energie Atomique Nouveaux composes silanes porteurs d'une chaine carbonee cyclique comprenant une fonction alcyne pour fonctionnaliser des supports solides et immobiliser sur ces supports des molecules biologiques
EP2529226B1 (en) 2010-01-25 2017-03-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) Silylated biomolecules
CN101845814B (zh) * 2010-05-18 2011-08-17 金文成 具有自监测功能的复合材料智能锚具及其制备方法
JP5751580B2 (ja) * 2011-04-28 2015-07-22 国立研究開発法人産業技術総合研究所 メトキシオリゴエチレングリコール−シラン化合物表面修飾材料
CN105061489B (zh) 2015-08-25 2019-03-05 深圳市华星光电技术有限公司 一种支化型有机硅材料及制备液晶面板的方法
JP7104911B2 (ja) * 2018-01-31 2022-07-22 国立研究開発法人産業技術総合研究所 標的物質検出方法及び導波モードセンサ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8200442L (sv) * 1982-01-27 1983-07-28 Forsvarets Forsknings Forfarande vid detektion av organiska molekyler, sasom biomolekyler
JPH01181790A (ja) * 1988-01-18 1989-07-19 Toray Silicone Co Ltd 生理活性物質の固定化方法
EP0337081A1 (en) * 1988-03-31 1989-10-18 Bio-Rad Laboratories, Inc. Biospecific assay using a derivatized glass surface
DD285099A5 (de) * 1989-06-20 1990-12-05 Klinikum Berlin Buch,Dd Verfahren zur aktivierung von polystyren-festkoerperflaechen
DE4039677A1 (de) * 1990-12-12 1992-06-17 Boehringer Mannheim Gmbh Universalbindefilm
DE4435728A1 (de) * 1994-01-19 1995-07-20 Boehringer Mannheim Gmbh Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix

Also Published As

Publication number Publication date
EP0664452A2 (de) 1995-07-26
ATE221660T1 (de) 2002-08-15
EP0664452B1 (de) 2002-07-31
JP3214795B2 (ja) 2001-10-02
EP0664452A3 (de) 1996-10-23
JPH07260790A (ja) 1995-10-13

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