ES2179967T3 - Procedimiento de preparacion de compuestos 3-hidroxilados que contienen un heterociclo de seis eslabones. - Google Patents

Procedimiento de preparacion de compuestos 3-hidroxilados que contienen un heterociclo de seis eslabones.

Info

Publication number
ES2179967T3
ES2179967T3 ES97102443T ES97102443T ES2179967T3 ES 2179967 T3 ES2179967 T3 ES 2179967T3 ES 97102443 T ES97102443 T ES 97102443T ES 97102443 T ES97102443 T ES 97102443T ES 2179967 T3 ES2179967 T3 ES 2179967T3
Authority
ES
Spain
Prior art keywords
group
acid
preparation
microbic
heterocicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97102443T
Other languages
English (en)
Inventor
Takeshi Sakamoto
Yukie Takai
Reiko Sashida
Makoto Ueda
Toru Nagasawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Corp filed Critical Mitsubishi Chemical Corp
Application granted granted Critical
Publication of ES2179967T3 publication Critical patent/ES2179967T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/88Serratia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE DISPONE UN METODO PARA PRODUCIR UN COMPUESTO 3-HIDROXIDO CICLICO DE SEIS MIEMBROS QUE CONTIENE NITROGENO. ESPECIALMENTE, SE PERMITE QUE CELULAS MICROBICAS DE UN MICROORGANISMO Y/O UNA PREPARACION OBTENIDA A PARTIR DE LAS CELULAS MICROBICAS ACTUEN EN UN DERIVADO DE ACIDO NICOTINICO O UN DERIVADO DE ACIDO 2PIRAZINACARBOXILICO REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL: EN DONDE R{SUB,1} Y R{SUB,2} PUEDEN SER LO MISMO O DIFERENTES, REPRESENTANDO UN ATOMO DE HIDROGENO, UN ATOMO DE HALOGENO, UN GRUPO HIDROXILO, UN GRUPO AMINO, UN GRUPO CARBOXILO, UN GRUPO CIANO, UN GRUPO OXIMA O UN GRUPO ALQUILO CON UN NUMERO DE ATOMO O ATOMOS DE CARBONO DE 1 A 5 RESPECTIVAMENTE, Y A REPRESENTA UN ATOMO DE CARBONO O UN ATOMO DE NITROGENO, LAS CELULAS MICROBICAS Y/O LA PREPARACION OBTENIDA A PARTIR DE LAS CELULAS MICROBICAS TENIENDO LA CAPACIDAD DE LLEVAR A CABO LA HIDROXILACION DEL DERIVADO DE ACIDO NICOTINICO O EL DERIVADO DE ACIDO 2PIRAZINACARBOXILICO ACOMPAÑADA DE LA DESCARBOXILACION DEL GRUPO CARBOXILO.
ES97102443T 1996-02-15 1997-02-14 Procedimiento de preparacion de compuestos 3-hidroxilados que contienen un heterociclo de seis eslabones. Expired - Lifetime ES2179967T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2784496 1996-02-15

Publications (1)

Publication Number Publication Date
ES2179967T3 true ES2179967T3 (es) 2003-02-01

Family

ID=12232234

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97102443T Expired - Lifetime ES2179967T3 (es) 1996-02-15 1997-02-14 Procedimiento de preparacion de compuestos 3-hidroxilados que contienen un heterociclo de seis eslabones.

Country Status (4)

Country Link
US (1) US5763232A (es)
EP (1) EP0790315B1 (es)
DE (1) DE69713819T2 (es)
ES (1) ES2179967T3 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH658867A5 (de) * 1984-02-22 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
IN170700B (es) * 1989-12-20 1992-05-02 Lonza Ag
JPH04365494A (ja) * 1990-11-08 1992-12-17 Lonza Ag ヒドロキシル化されたピラジン誘導体を製造するための微生物学的方法
FI922125L (fi) * 1991-06-21 1992-12-22 Lonza Ag Mikrobidogiskt foerfarande foer framstaellning av 5-hydroxipyrazinkarboxylsyra
MX9206934A (es) * 1991-12-05 1993-07-01 Lonza Ag Procedimiento microbiologico para la preparacion de acidos carboxilicos hidroxi-heterociclicos
JP3275353B2 (ja) * 1992-02-26 2002-04-15 三菱化学株式会社 6−ヒドロキシ含窒素6員環化合物の製造方法
CZ282939B6 (cs) * 1992-03-04 1997-11-12 Lonza A.G. Mikrobiologický způsob hydroxylace dusíkatých heterocyklických karboxylových kyselin

Also Published As

Publication number Publication date
EP0790315A2 (en) 1997-08-20
EP0790315B1 (en) 2002-07-10
DE69713819D1 (de) 2002-08-14
EP0790315A3 (en) 1999-04-14
DE69713819T2 (de) 2003-03-13
US5763232A (en) 1998-06-09

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