ES2182020T3 - Proceso de produccion de acido aspartico. - Google Patents
Proceso de produccion de acido aspartico.Info
- Publication number
- ES2182020T3 ES2182020T3 ES97901152T ES97901152T ES2182020T3 ES 2182020 T3 ES2182020 T3 ES 2182020T3 ES 97901152 T ES97901152 T ES 97901152T ES 97901152 T ES97901152 T ES 97901152T ES 2182020 T3 ES2182020 T3 ES 2182020T3
- Authority
- ES
- Spain
- Prior art keywords
- ammonic
- calcium
- smoking
- fumarate
- aspartic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 title abstract 3
- 235000003704 aspartic acid Nutrition 0.000 title abstract 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 3
- 229910052791 calcium Inorganic materials 0.000 abstract 3
- 239000011575 calcium Substances 0.000 abstract 3
- 238000000855 fermentation Methods 0.000 abstract 3
- 230000004151 fermentation Effects 0.000 abstract 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-L fumarate(2-) Chemical compound [O-]C(=O)\C=C\C([O-])=O VZCYOOQTPOCHFL-OWOJBTEDSA-L 0.000 abstract 3
- 230000000391 smoking effect Effects 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- 239000002689 soil Substances 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940009098 aspartate Drugs 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 abstract 1
- 239000000920 calcium hydroxide Substances 0.000 abstract 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000001530 fumaric acid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 239000000779 smoke Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA INVENCION PROPORCIONA UN PROCESO PARA LA PREPARACION DE ACIDO ASPARTICO A TRAVES DE UN PROCESO DE FERMENTACION PARA LA PREPARACION DE FUMARATO AMONICO, EN EL QUE EL PH DEL CALDO DE FERMENTACION ESTA CONTROLADO MEDIANTE LA ADICION DE UNA BASE DE CALCIO PARA PRODUCIR UN PRECIPITADO DE FUMARATO CALCICO, CARACTERIZADO PORQUE EL FUMARATO AMONICO SE PRODUCE SEPARANDO EL PRECIPITADO DE FUMARATO CALCICO DEL CALDO DE FERMENTACION, Y HACIENDOLO REACCIONAR CON UN REACTIVO SELECCIONADO DE ENTRE AMONIACO, CARBONATO AMONICO, AMONIACO EN COMBINACION CON CO 2 Y MEZCLAS DE LOS MISMOS, PARA FORMAR FUMARATO AMONICO Y UN CO-PRODUCTO SELECCIONADO DE CARBONATO CALCICO E HIDROXIDO CALCICO, EN EL QUE LA ENERGIA DE LA NEUTRALIZACION INDIRECTA DEL ACIDO FUMARICO POR EL AMONIACO SIRVE COMO FUERZA MOTRIZ PARA LA CONVERSION DE FUMARATO CALCICO EN EL PRODUCTO DE FUMARATO AMONICO DESEADO Y PARA LA REGENERACION DE UN REACTIVO DE BASE DE CALCIO, Y EN EL QUE EL FUMARATO DE DIAMONIO SE CONVIERTE ENZIMATICAMENTE EN UN ASPARTATO AMONICO Y SE ACIDULA PARA FORMAR ACIDO ASPARTICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL11684996A IL116849A (en) | 1996-01-22 | 1996-01-22 | Process for the preparation of aspartic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2182020T3 true ES2182020T3 (es) | 2003-03-01 |
Family
ID=11068464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97901152T Expired - Lifetime ES2182020T3 (es) | 1996-01-22 | 1997-01-21 | Proceso de produccion de acido aspartico. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5972662A (es) |
| EP (1) | EP0876499B1 (es) |
| AT (1) | ATE223494T1 (es) |
| AU (1) | AU1449797A (es) |
| DE (1) | DE69715151T2 (es) |
| ES (1) | ES2182020T3 (es) |
| IL (1) | IL116849A (es) |
| WO (1) | WO1997027312A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6071728A (en) * | 1997-01-09 | 2000-06-06 | Amylum Belgium, N.V. | Process for the production of crystalline aspartic acid |
| IL119986A (en) * | 1997-01-09 | 2000-10-31 | Amylum Nv | Process for the production of crystalline aspartic acid |
| RU2174558C1 (ru) * | 2000-12-07 | 2001-10-10 | Закрытое акционерное общество "Биоамид" | Способ получения l-аспарагиновой кислоты |
| US20060035310A1 (en) * | 2004-08-13 | 2006-02-16 | Millipore Corporation | Media for recovery of microorganism in the presence of antibiotics |
| CN107475320A (zh) * | 2017-08-23 | 2017-12-15 | 安徽雪郎生物科技股份有限公司 | L‑天门冬氨酸的绿色生产方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB146411A (en) * | 1915-09-28 | 1921-10-03 | Carl Wehmer | Improved manufacture of fumaric acid |
| US2327191A (en) * | 1939-12-07 | 1943-08-17 | Pfizer & Co C | Production of fumaric acid |
| US3030276A (en) * | 1960-02-09 | 1962-04-17 | Alfred M Thomsen | Method of making fumaric acid and urea from lignified cellulose |
| GB1004218A (en) * | 1962-05-26 | 1965-09-15 | Ajinomoto Kk | A process for producing l-aspartic acid |
| IT1023343B (it) * | 1974-11-21 | 1978-05-10 | Liquichimica Spa | Metodo di produzione di acido l aspartico per fermentazione di idrocarburi |
| JPS57138383A (en) * | 1981-02-20 | 1982-08-26 | Tanabe Seiyaku Co Ltd | Preparation of l-aspartic acid |
| US4877731A (en) * | 1988-06-27 | 1989-10-31 | E. I. Du Pont De Nemours And Company | Fermentation process for carboxylic acids |
| US5352825A (en) * | 1993-07-06 | 1994-10-04 | Hoarmann & Reimer Corp. | Recovery of organic acid salts from impure process streams by addition of bases |
-
1996
- 1996-01-22 IL IL11684996A patent/IL116849A/xx not_active IP Right Cessation
-
1997
- 1997-01-21 AU AU14497/97A patent/AU1449797A/en not_active Abandoned
- 1997-01-21 ES ES97901152T patent/ES2182020T3/es not_active Expired - Lifetime
- 1997-01-21 AT AT97901152T patent/ATE223494T1/de not_active IP Right Cessation
- 1997-01-21 US US09/101,779 patent/US5972662A/en not_active Expired - Lifetime
- 1997-01-21 WO PCT/GB1997/000176 patent/WO1997027312A1/en not_active Ceased
- 1997-01-21 DE DE69715151T patent/DE69715151T2/de not_active Expired - Fee Related
- 1997-01-21 EP EP97901152A patent/EP0876499B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69715151D1 (de) | 2002-10-10 |
| DE69715151T2 (de) | 2003-02-27 |
| EP0876499B1 (en) | 2002-09-04 |
| WO1997027312A1 (en) | 1997-07-31 |
| EP0876499A1 (en) | 1998-11-11 |
| IL116849A (en) | 1999-12-31 |
| ATE223494T1 (de) | 2002-09-15 |
| US5972662A (en) | 1999-10-26 |
| AU1449797A (en) | 1997-08-20 |
| IL116849A0 (en) | 1996-07-23 |
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