ES2183220T3 - Curacion de heridas y tratamientos de la fibrosis. - Google Patents

Curacion de heridas y tratamientos de la fibrosis.

Info

Publication number
ES2183220T3
ES2183220T3 ES97947761T ES97947761T ES2183220T3 ES 2183220 T3 ES2183220 T3 ES 2183220T3 ES 97947761 T ES97947761 T ES 97947761T ES 97947761 T ES97947761 T ES 97947761T ES 2183220 T3 ES2183220 T3 ES 2183220T3
Authority
ES
Spain
Prior art keywords
wounds
healing
fibrosis
fibrosis treatments
treatments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97947761T
Other languages
English (en)
Inventor
Mark William James Ferguson
Sharon O'kane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Renovo Ltd
Original Assignee
Renovo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625148.3A external-priority patent/GB9625148D0/en
Application filed by Renovo Ltd filed Critical Renovo Ltd
Application granted granted Critical
Publication of ES2183220T3 publication Critical patent/ES2183220T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE PRESENTAN COMPOSICIONES PARA SU USO EN EL TRATAMIENTO DE HERIDAS Y DE FIBROSIS QUE COMPRENDEN UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN COMPUESTO QUE MODULA EL ENSAMBLAJE Y LA ORGANIZACION DE LA ACTINA INTRACELULAR Y/O EXTRACELULARMENTE Y UN VEHICULO FARMACOLOGICAMENTE ACEPTABLE, EL COMPUESTO PROMUEVE LA VELOCIDAD DE CICATRIZACION DE LAS HERIDAS Y TAMBIEN EVITA Y REDUCE LA FIBROSIS. UN COMPUESTO ADECUADO ES LA GELSOLINA.
ES97947761T 1996-12-04 1997-12-04 Curacion de heridas y tratamientos de la fibrosis. Expired - Lifetime ES2183220T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9625148.3A GB9625148D0 (en) 1996-12-04 1996-12-04 Wound healing
US3211596P 1996-12-05 1996-12-05

Publications (1)

Publication Number Publication Date
ES2183220T3 true ES2183220T3 (es) 2003-03-16

Family

ID=26310539

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97947761T Expired - Lifetime ES2183220T3 (es) 1996-12-04 1997-12-04 Curacion de heridas y tratamientos de la fibrosis.

Country Status (11)

Country Link
US (2) US20020103112A1 (es)
EP (1) EP0941108B1 (es)
JP (1) JP2001505219A (es)
AT (1) ATE226084T1 (es)
AU (1) AU744750B2 (es)
CA (1) CA2274002A1 (es)
DE (1) DE69716460T2 (es)
DK (1) DK0941108T3 (es)
ES (1) ES2183220T3 (es)
PT (1) PT941108E (es)
WO (1) WO1998024465A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69927987T2 (de) * 1998-08-13 2006-11-09 Hadasit Medical Research Services & Development Co. Ltd. Hemmung von mit gewebetrauma verbundenen pathogenen prozessen
CA2388761A1 (en) * 2001-06-18 2002-12-18 Pfizer Inc. Wound healing biomarkers
US7301020B2 (en) * 2003-06-19 2007-11-27 Wisconsin Alumni Research Foundation Macrolide analogs and methods for identifying same
US9408891B2 (en) * 2003-11-12 2016-08-09 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
WO2005046454A2 (en) * 2003-11-12 2005-05-26 Trustrees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
KR101300929B1 (ko) * 2004-05-12 2013-08-27 더 브리검 앤드 우먼즈 하스피털, 인크. 감염 치료를 위한 겔솔린의 용도
EP1945256B1 (en) * 2005-10-25 2012-07-04 Women's & Children's Health Research Institute Methods and compositions for improving wound repair
AU2006308431B2 (en) * 2005-10-25 2011-11-10 Adelaide Research & Innovation Pty Ltd Methods and compositions for modulating wound repair
KR101556790B1 (ko) 2006-03-15 2015-10-01 더 브리검 앤드 우먼즈 하스피털, 인크. 염증성 질환의 진단 및 치료를 위한 겔솔린의 용도
ES2651619T3 (es) * 2006-03-15 2018-01-29 The Brigham And Women's Hospital, Inc. Uso de gelsolina para tratar esclerosis múltiple y diagnosticar enfermedades neurológicas
GB0724231D0 (en) * 2007-12-12 2008-01-30 Renono Ltd Methods for inhibiting scarring
HUE032875T2 (en) * 2008-01-25 2017-11-28 Massachusetts Gen Hospital Diagnostic and therapeutic applications of gelsolin in renal failure
GB201003652D0 (en) * 2010-03-05 2010-04-21 Univ Cardiff Molecular target for healing or treating wounds
EP3263121B1 (en) * 2010-12-21 2019-02-27 Leidos, Inc. Methods and compositions for wound treatment
CN118806900B (zh) * 2024-06-21 2025-09-05 中山大学附属第一医院 抑制capg活性的物质在制备治疗肾损伤所致肾脏纤维化的产品中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929442A (en) 1986-09-26 1990-05-29 Exovir, Inc. Compositions suitable for human topical application including a growth factor and/or related materials
DE3889479T2 (de) 1987-02-27 1994-12-22 Eastman Kodak Co Mit Nieder-pI-Protein beschichtete Membranstruktur und Verfahren zu ihrer Herstellung und Verwendung.
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
JP3616392B2 (ja) 1990-04-11 2005-02-02 ザ・ブリガム・アンド・ウイメンズ・ホスピタル・インコーポレイテッド アクチン結合性化合物の療法的使用
AU8647991A (en) 1991-08-26 1993-03-16 State of Oregon Acting by and Through The State of Board of Higher Education on Behalf of The Oregon Health Sciences University, The Keratinocyte-derived conditioned medium as a source of growth factors
GB9206861D0 (en) * 1992-03-28 1992-05-13 Univ Manchester Wound healing and treatment of fibrotic disorders
GB2304047A (en) * 1995-08-09 1997-03-12 Univ Manchester Pharmaceutical compositions containing cytokines

Also Published As

Publication number Publication date
AU5401098A (en) 1998-06-29
US7566446B2 (en) 2009-07-28
DE69716460T2 (de) 2003-06-26
ATE226084T1 (de) 2002-11-15
AU744750B2 (en) 2002-02-28
JP2001505219A (ja) 2001-04-17
WO1998024465A1 (en) 1998-06-11
CA2274002A1 (en) 1998-06-11
EP0941108B1 (en) 2002-10-16
US20070087969A1 (en) 2007-04-19
DK0941108T3 (da) 2002-11-18
HK1025732A1 (en) 2000-11-24
DE69716460D1 (de) 2002-11-21
PT941108E (pt) 2003-01-31
US20020103112A1 (en) 2002-08-01
EP0941108A1 (en) 1999-09-15

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