ES2183472T3 - Sellado oseo mejorado. - Google Patents

Sellado oseo mejorado.

Info

Publication number
ES2183472T3
ES2183472T3 ES99124374T ES99124374T ES2183472T3 ES 2183472 T3 ES2183472 T3 ES 2183472T3 ES 99124374 T ES99124374 T ES 99124374T ES 99124374 T ES99124374 T ES 99124374T ES 2183472 T3 ES2183472 T3 ES 2183472T3
Authority
ES
Spain
Prior art keywords
polyester
oligomers
sealed
improved
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99124374T
Other languages
English (en)
Inventor
Wolfgang Dr Ritter
Robert Dr Wenz
Ralf Dr Krotz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2183472T3 publication Critical patent/ES2183472T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Prostheses (AREA)

Abstract

Sellado óseo, apropiado para el corte de hemorragias locales en hueso, constituido por oligómeros de poliéster de ácido láctico, ácido glicólico y glicerina, caracterizado porque está constituido adicionalmente por polietilenglicol (PEG), con un peso molecular de PEG de 8000 a 10000.
ES99124374T 1998-12-19 1999-12-07 Sellado oseo mejorado. Expired - Lifetime ES2183472T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19858891A DE19858891A1 (de) 1998-12-19 1998-12-19 Verbesserte Knochensiegel

Publications (1)

Publication Number Publication Date
ES2183472T3 true ES2183472T3 (es) 2003-03-16

Family

ID=7891861

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99124374T Expired - Lifetime ES2183472T3 (es) 1998-12-19 1999-12-07 Sellado oseo mejorado.

Country Status (6)

Country Link
US (1) US6420454B1 (es)
EP (1) EP1010436B1 (es)
JP (1) JP2000185091A (es)
AT (1) ATE226096T1 (es)
DE (2) DE19858891A1 (es)
ES (1) ES2183472T3 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413536B1 (en) * 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
CA2516728C (en) * 2002-02-22 2014-05-20 Biomatera Inc. Biodegradable bone implant material
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
CZ294328B6 (cs) * 2002-08-22 2004-11-10 Pliva-Lachema A. S. Biodegradabilní kompozice s prolongovaným uvolňováním biologicky aktivní látky a způsob její výroby
US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
ATE482695T1 (de) 2002-12-13 2010-10-15 Durect Corp Orale darreichungsform mit flüssigen hochviskosen trägersystemen
US7989000B2 (en) 2003-09-23 2011-08-02 Orthocon, Inc. Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects
AU2004279319B2 (en) * 2003-09-23 2010-11-04 Abyrx, Inc Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
US8603528B2 (en) * 2004-09-16 2013-12-10 Abyrx, Inc. Compositions and method for the reduction of post-operative pain
AU2005287175B2 (en) 2004-09-17 2011-12-01 Durect Corporation Sustained local anesthetic composition containing preferably a sugar ester such as SAIB
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
JP2010529091A (ja) 2007-06-06 2010-08-26 インノテーレ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 水硬性セメントをベースとするインプラント材料ならびにその使用
EP2219622A1 (en) 2007-12-06 2010-08-25 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
EP2773358A4 (en) * 2011-11-01 2015-12-02 Abyrx Inc COMPOSITIONS AND METHODS FOR BLOOD-TREATMENT
TW201521769A (zh) 2013-03-15 2015-06-16 Durect Corp 具有流變改質劑以減少溶解變異性之組成物
US9775853B2 (en) 2013-03-15 2017-10-03 Biomet Manufacturing, Llc. Hemostatic compositions and methods
SG11201811760VA (en) 2016-07-06 2019-01-30 Durect Corp Oral dosage form with drug composition, barrier layer and drug layer
JP6901721B2 (ja) * 2017-03-30 2021-07-14 国立大学法人東海国立大学機構 骨髄止血剤
EP3615586B1 (en) * 2017-04-28 2021-02-17 Evonik Operations GmbH Biodegradable bone glue
CN115666621A (zh) 2020-01-13 2023-01-31 度勒科特公司 具有减少的杂质的持续释放药物递送系统及相关方法
CN112156223A (zh) * 2020-10-13 2021-01-01 江苏理工学院 一种类骨蜡止血胶及其制备方法
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584080A (en) * 1977-12-05 1981-02-04 Ethicon Inc Absorbable hemostatic composition
DE3229540A1 (de) * 1982-08-07 1984-02-09 Henkel KGaA, 4000 Düsseldorf Resorbierbare knochenwachse
DE3716302C2 (de) * 1987-05-15 1996-02-01 Henkel Kgaa Verbesserte resorbierbare Knochenwachse und ihre Verwendung
JPH0622570B2 (ja) * 1989-01-31 1994-03-30 多木化学株式会社 生体材料
PT99345A (pt) * 1990-10-30 1992-09-30 Alza Corp Processo para a preparacao de sistemas apropriados para a libertacao de agentes terapeuticos
DE4235312A1 (de) * 1991-10-23 1993-04-29 Boehringer Ingelheim Kg Halbfeste mischungen aus oligomeren und/oder polymeren auf der basis von milchsaeure, verfahren zu deren herstellung und deren verwendung als resorbierbare implantate
JP3113108B2 (ja) * 1992-11-25 2000-11-27 多木化学株式会社 止血剤
US5688900A (en) * 1995-01-19 1997-11-18 Ethicon, Inc. Absorbable polyalkylene diglycolates
CA2167455A1 (en) * 1995-01-19 1996-07-20 Kevin Cooper Absorbable polyalkylene diglycolates

Also Published As

Publication number Publication date
US6420454B1 (en) 2002-07-16
JP2000185091A (ja) 2000-07-04
DE59903087D1 (de) 2002-11-21
ATE226096T1 (de) 2002-11-15
EP1010436B1 (de) 2002-10-16
EP1010436A1 (de) 2000-06-21
DE19858891A1 (de) 2000-06-21

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