ES2183595T3 - Empleo de ectoina o derivados de ectoina en formulaciones. - Google Patents
Empleo de ectoina o derivados de ectoina en formulaciones.Info
- Publication number
- ES2183595T3 ES2183595T3 ES99938318T ES99938318T ES2183595T3 ES 2183595 T3 ES2183595 T3 ES 2183595T3 ES 99938318 T ES99938318 T ES 99938318T ES 99938318 T ES99938318 T ES 99938318T ES 2183595 T3 ES2183595 T3 ES 2183595T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- ectoin
- compounds
- formulas
- moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- WQXNXVUDBPYKBA-YFKPBYRVSA-N ectoine Chemical compound CC1=[NH+][C@H](C([O-])=O)CCN1 WQXNXVUDBPYKBA-YFKPBYRVSA-N 0.000 title 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- -1 R2 H Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000004927 skin cell Anatomy 0.000 abstract 1
- 230000006641 stabilisation Effects 0.000 abstract 1
- 238000011105 stabilization Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Empleo de uno o varios compuestos seleccionados a partir de los compuestos de las fórmulas Ia y Ib las sales compatibles desde el punto de vista fisiológico de compuestos de las fórmulas Ia y Ib, y las formas estereoisómeras de compuestos de las fórmulas Ia y Ib, significando R1 H o alquilo, R2 H, COOH, COO-alquilo o CO-NH-R5, R3 y R4 H u OH independientemente entre sí en cada caso, n 1, 2 o 3, alquilo un resto alquilo con 1 a 4 átomos de carbono, y R5 H, alquilo, un resto aminoácido, un resto dipéptido o un resto tripéptido, para la obtención de una formulación para la protección y para el estabilizado de ácidos nucleicos de células dérmicas humanas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19834816A DE19834816A1 (de) | 1998-08-01 | 1998-08-01 | Verwendung von Ectoin oder Ectoin-Derivaten in kosmetischen Formulierungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2183595T3 true ES2183595T3 (es) | 2003-03-16 |
Family
ID=7876165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99938318T Expired - Lifetime ES2183595T3 (es) | 1998-08-01 | 1999-07-22 | Empleo de ectoina o derivados de ectoina en formulaciones. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1100456B1 (es) |
| JP (1) | JP5116917B2 (es) |
| AU (1) | AU748035B2 (es) |
| DE (2) | DE19834816A1 (es) |
| ES (1) | ES2183595T3 (es) |
| WO (1) | WO2000007558A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1125583A1 (de) * | 2000-02-14 | 2001-08-22 | Bitop Gesellschaft für biotechnische Optimierung MbH | Verwendung von kompatiblen Soluten als Inhibitoren des enzymatischen Abbaus von makromolekularen Biopolymeren |
| DE10014631A1 (de) * | 2000-03-24 | 2001-09-27 | Merck Patent Gmbh | Verwendung von Ectoin oder Ectoin-Derivaten zur Prophylaxe und/oder Behandlung von UV-induzierter Immunsuppression |
| ES2233630T3 (es) * | 2000-04-12 | 2005-06-16 | Bitop Aktiengesellschaft Fur Biotechnische Optimierung | Uso de solutos compatibles como sustancias con propiedades barredoras de radicales. |
| DE10043456A1 (de) * | 2000-09-04 | 2002-03-14 | Merck Patent Gmbh | Verwendung von Ectoin oder Ectoin-Derivaten zur Stabilisierung von p53 |
| JP4540872B2 (ja) * | 2001-04-02 | 2010-09-08 | 株式会社資生堂 | 乾燥による皮膚傷害の抑制剤もしくは修復剤 |
| DE10137260A1 (de) | 2001-07-31 | 2003-02-13 | Merck Patent Gmbh | Kosmetische Formulierung enthaltend Dihydroxyaceton |
| DE10214257A1 (de) | 2002-03-28 | 2003-10-16 | Merck Patent Gmbh | Verwendung von kompatiblen Soluten zur Inhibierung der Freisetzung von Ceramiden |
| DE10330768A1 (de) | 2003-07-07 | 2005-02-24 | bitop Aktiengesellschaft für biotechnische Optimierung | Verwendung von aus extremophilen Bakterien gewonnenen Osmolyten zur Herstellung von inhalierbaren Arzneimitteln zur Prophylaxe und Behandlung pulmonaler und kardiovaskulärer Erkrankungen, sowie eines Osmolyte als Wirkstoffbestandteil enthaltende Inhalationsvorrichtung |
| WO2005113147A2 (en) | 2004-04-08 | 2005-12-01 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| FR2900818B1 (fr) * | 2006-05-15 | 2010-09-24 | Lvmh Rech | Compositions cosmetiques aqueuses, en particulier lotions hydratantes |
| CA2761675A1 (en) | 2009-05-11 | 2010-11-18 | Biomatrica, Inc. | Compositions and methods for biological sample storage |
| US9376709B2 (en) | 2010-07-26 | 2016-06-28 | Biomatrica, Inc. | Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures |
| EP2598661B1 (en) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| US9725703B2 (en) | 2012-12-20 | 2017-08-08 | Biomatrica, Inc. | Formulations and methods for stabilizing PCR reagents |
| WO2015191632A1 (en) | 2014-06-10 | 2015-12-17 | Biomatrica, Inc. | Stabilization of thrombocytes at ambient temperatures |
| DE102014113781A1 (de) * | 2014-09-23 | 2016-03-24 | Bitop Ag | Solut und Solutgemisch sowie eine Zusammensetzung enthaltend mindestens ein Solut zur Verwendung bei der Prävention oder Behandlung von durch Schwebstaub verursachter kosmetischer oder pathologischer Effloreszenzen |
| DE102015121050A1 (de) * | 2015-12-03 | 2017-06-08 | Bitop Ag | Kompatibles Solut oder Solutgemisch zur Verwendung bei der Prävention oder Behandlung von Krankheiten mit Barrieredefekten in Epithelgeweben |
| ES2946184T3 (es) | 2015-12-08 | 2023-07-13 | Biomatrica Inc | Reducción de la velocidad de eritrosedimentación |
| EP3495363B1 (en) * | 2016-07-28 | 2023-08-23 | Shionogi & Co., Ltd | Nitrogen-containing condensed ring compounds having dopamine d3 receptor antagonistic effect |
| US20200030214A1 (en) | 2017-03-06 | 2020-01-30 | Merck Patent Gmbh | Use of compatible solutes |
| CN111936142A (zh) * | 2018-04-05 | 2020-11-13 | 株式会社资生堂 | Asmt表达促进剂 |
| KR20220042171A (ko) | 2019-08-01 | 2022-04-04 | 메르크 파텐트 게엠베하 | 각질화 장애의 예방 및 감소 및 관련 미용제 |
| EP4382089A1 (en) | 2022-12-07 | 2024-06-12 | Kao Germany GmbH | Aqueous composition for semi-permanent straightening keratin fibers especially human hair |
| CN118286105A (zh) * | 2024-04-26 | 2024-07-05 | 深圳市迪克曼生物科技有限公司 | 依克多因神经酰胺在皮肤护理中的用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8527587D0 (en) * | 1985-11-08 | 1985-12-11 | Britax Excelsior | Tongue & buckle fasteners |
| JPS63233912A (ja) * | 1986-12-30 | 1988-09-29 | チャールス オブ ザ リッツ グループ リミテッド | 紫外線吸収性化合物および遮光剤 |
| IL100810A (en) * | 1992-01-30 | 1996-12-05 | Yeda Res & Dev | Pharmaceutical preparations including 2 - methyl - carboxy - 5 - hydroxy - tetrahydropyrimidine and / or 2 - methyl - 4 - carboxy - tetrahydropyrimidine, plywood methods |
| DE4342560A1 (de) * | 1993-12-14 | 1995-06-22 | Marbert Gmbh | Ectoin und Ectoinderivate als Feuchtigkeitsspender in Kosmetikprodukten |
| JPH08283122A (ja) * | 1995-04-12 | 1996-10-29 | Kao Corp | 皮膚化粧料 |
| CN1105554C (zh) * | 1996-09-27 | 2003-04-16 | 尤尼利弗公司 | 包含能模拟视黄酸对皮肤之作用的化合物结合物的护肤组合物 |
| US5738858A (en) * | 1996-09-27 | 1998-04-14 | Cheseborough-Pond's Usa Co., Division Of Conopco, Inc. | Skin care compositions containing fatty hydroxyethyl imidazoline surfactants and retinol or retinyl ester |
-
1998
- 1998-08-01 DE DE19834816A patent/DE19834816A1/de not_active Withdrawn
-
1999
- 1999-07-22 JP JP2000563244A patent/JP5116917B2/ja not_active Expired - Lifetime
- 1999-07-22 WO PCT/EP1999/005237 patent/WO2000007558A1/de not_active Ceased
- 1999-07-22 ES ES99938318T patent/ES2183595T3/es not_active Expired - Lifetime
- 1999-07-22 EP EP99938318A patent/EP1100456B1/de not_active Expired - Lifetime
- 1999-07-22 AU AU52865/99A patent/AU748035B2/en not_active Ceased
- 1999-07-22 DE DE59902868T patent/DE59902868D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1100456A1 (de) | 2001-05-23 |
| WO2000007558A1 (de) | 2000-02-17 |
| AU748035B2 (en) | 2002-05-30 |
| EP1100456B1 (de) | 2002-09-25 |
| JP2002522366A (ja) | 2002-07-23 |
| JP5116917B2 (ja) | 2013-01-09 |
| DE19834816A1 (de) | 2000-02-03 |
| AU5286599A (en) | 2000-02-28 |
| DE59902868D1 (de) | 2002-10-31 |
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