|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
US6001335A
(en)
|
1989-12-22 |
1999-12-14 |
Imarx Pharmaceutical Corp. |
Contrasting agents for ultrasonic imaging and methods for preparing the same
|
|
US5469854A
(en)
|
1989-12-22 |
1995-11-28 |
Imarx Pharmaceutical Corp. |
Methods of preparing gas-filled liposomes
|
|
US5305757A
(en)
|
1989-12-22 |
1994-04-26 |
Unger Evan C |
Gas filled liposomes and their use as ultrasonic contrast agents
|
|
US5705187A
(en)
|
1989-12-22 |
1998-01-06 |
Imarx Pharmaceutical Corp. |
Compositions of lipids and stabilizing materials
|
|
US5656211A
(en)
|
1989-12-22 |
1997-08-12 |
Imarx Pharmaceutical Corp. |
Apparatus and method for making gas-filled vesicles of optimal size
|
|
US20020150539A1
(en)
|
1989-12-22 |
2002-10-17 |
Unger Evan C. |
Ultrasound imaging and treatment
|
|
US5733572A
(en)
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
US6088613A
(en)
|
1989-12-22 |
2000-07-11 |
Imarx Pharmaceutical Corp. |
Method of magnetic resonance focused surgical and therapeutic ultrasound
|
|
US5773024A
(en)
|
1989-12-22 |
1998-06-30 |
Imarx Pharmaceutical Corp. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
|
US5922304A
(en)
|
1989-12-22 |
1999-07-13 |
Imarx Pharmaceutical Corp. |
Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
|
|
US5580575A
(en)
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
|
US6146657A
(en)
|
1989-12-22 |
2000-11-14 |
Imarx Pharmaceutical Corp. |
Gas-filled lipid spheres for use in diagnostic and therapeutic applications
|
|
US5776429A
(en)
|
1989-12-22 |
1998-07-07 |
Imarx Pharmaceutical Corp. |
Method of preparing gas-filled microspheres using a lyophilized lipids
|
|
US6551576B1
(en)
|
1989-12-22 |
2003-04-22 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
|
US5205290A
(en)
|
1991-04-05 |
1993-04-27 |
Unger Evan C |
Low density microspheres and their use as contrast agents for computed tomography
|
|
US5874062A
(en)
|
1991-04-05 |
1999-02-23 |
Imarx Pharmaceutical Corp. |
Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
|
|
MX9205298A
(es)
*
|
1991-09-17 |
1993-05-01 |
Steven Carl Quay |
Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
|
|
US6723303B1
(en)
|
1991-09-17 |
2004-04-20 |
Amersham Health, As |
Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
|
|
US6875420B1
(en)
|
1991-09-17 |
2005-04-05 |
Amersham Health As |
Method of ultrasound imaging
|
|
HUT72323A
(en)
*
|
1993-01-25 |
1996-04-29 |
Sonus Pharma Inc |
Phase shift colloids as ultrasound contrast agents
|
|
IL108416A
(en)
|
1993-01-25 |
1998-10-30 |
Sonus Pharma Inc |
Phase shift colloids as ultrasound contrast agents
|
|
EP0711179B2
(en)
*
|
1993-07-30 |
2010-09-01 |
IMCOR Pharmaceutical Co. |
Stabilized microbubble compositions for ultrasound
|
|
ATE197124T1
(de)
|
1993-09-09 |
2000-11-15 |
Schering Ag |
Wirkstoffe und gas enthaltende mikropartikel
|
|
US7083572B2
(en)
|
1993-11-30 |
2006-08-01 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Therapeutic delivery systems
|
|
ATE234638T1
(de)
*
|
1993-12-15 |
2003-04-15 |
Bracco Research Sa |
Gas-mischungen verwendbar als ultraschallkontrastmittel
|
|
US5736121A
(en)
|
1994-05-23 |
1998-04-07 |
Imarx Pharmaceutical Corp. |
Stabilized homogenous suspensions as computed tomography contrast agents
|
|
US5730955A
(en)
*
|
1994-08-02 |
1998-03-24 |
Molecular Biosystems, Inc. |
Process for making gas-filled microspheres containing a liquid hydrophobic barrier
|
|
US5965109A
(en)
*
|
1994-08-02 |
1999-10-12 |
Molecular Biosystems, Inc. |
Process for making insoluble gas-filled microspheres containing a liquid hydrophobic barrier
|
|
US5562893A
(en)
*
|
1994-08-02 |
1996-10-08 |
Molecular Biosystems, Inc. |
Gas-filled microspheres with fluorine-containing shells
|
|
US5540909A
(en)
*
|
1994-09-28 |
1996-07-30 |
Alliance Pharmaceutical Corp. |
Harmonic ultrasound imaging with microbubbles
|
|
US6743779B1
(en)
|
1994-11-29 |
2004-06-01 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
|
US5997898A
(en)
|
1995-06-06 |
1999-12-07 |
Imarx Pharmaceutical Corp. |
Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
|
|
US5804162A
(en)
|
1995-06-07 |
1998-09-08 |
Alliance Pharmaceutical Corp. |
Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
|
|
US5820850A
(en)
*
|
1995-06-07 |
1998-10-13 |
Molecular Biosystems, Inc. |
Gas-filled amino acid block co-polymer microspheres useful as ultrasound contrast agents
|
|
US6139819A
(en)
|
1995-06-07 |
2000-10-31 |
Imarx Pharmaceutical Corp. |
Targeted contrast agents for diagnostic and therapeutic use
|
|
US6231834B1
(en)
|
1995-06-07 |
2001-05-15 |
Imarx Pharmaceutical Corp. |
Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
|
|
US6521211B1
(en)
|
1995-06-07 |
2003-02-18 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Methods of imaging and treatment with targeted compositions
|
|
US6033645A
(en)
|
1996-06-19 |
2000-03-07 |
Unger; Evan C. |
Methods for diagnostic imaging by regulating the administration rate of a contrast agent
|
|
US5611344A
(en)
*
|
1996-03-05 |
1997-03-18 |
Acusphere, Inc. |
Microencapsulated fluorinated gases for use as imaging agents
|
|
CA2252617A1
(en)
|
1996-05-01 |
1997-11-06 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
|
US5976501A
(en)
*
|
1996-06-07 |
1999-11-02 |
Molecular Biosystems, Inc. |
Use of pressure resistant protein microspheres encapsulating gases as ultrasonic imaging agents for vascular perfusion
|
|
US5837221A
(en)
*
|
1996-07-29 |
1998-11-17 |
Acusphere, Inc. |
Polymer-lipid microencapsulated gases for use as imaging agents
|
|
US6414139B1
(en)
|
1996-09-03 |
2002-07-02 |
Imarx Therapeutics, Inc. |
Silicon amphiphilic compounds and the use thereof
|
|
DE69718519T2
(de)
|
1996-09-11 |
2003-11-06 |
Imarx Pharmaceutical Corp., Tucson |
Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
|
|
US5846517A
(en)
|
1996-09-11 |
1998-12-08 |
Imarx Pharmaceutical Corp. |
Methods for diagnostic imaging using a renal contrast agent and a vasodilator
|
|
US6090800A
(en)
|
1997-05-06 |
2000-07-18 |
Imarx Pharmaceutical Corp. |
Lipid soluble steroid prodrugs
|
|
US6537246B1
(en)
|
1997-06-18 |
2003-03-25 |
Imarx Therapeutics, Inc. |
Oxygen delivery agents and uses for the same
|
|
US6143276A
(en)
|
1997-03-21 |
2000-11-07 |
Imarx Pharmaceutical Corp. |
Methods for delivering bioactive agents to regions of elevated temperatures
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
ES2296332T3
(es)
*
|
1997-04-30 |
2008-04-16 |
Point Biomedical Corporation |
Microparticulas que son utilizadas como agentes de contraste para la liberacion de medicamentos en el flujo sanguineo.
|
|
US7452551B1
(en)
|
2000-10-30 |
2008-11-18 |
Imarx Therapeutics, Inc. |
Targeted compositions for diagnostic and therapeutic use
|
|
US6416740B1
(en)
|
1997-05-13 |
2002-07-09 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Acoustically active drug delivery systems
|
|
AU7702798A
(en)
|
1997-05-30 |
1998-12-30 |
Alliance Pharmaceutical Corporation |
Methods and apparatus for monitoring and quantifying the movement of fluid
|
|
US6045777A
(en)
*
|
1997-06-30 |
2000-04-04 |
Acusphere, Inc. |
Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
|
|
US6548047B1
(en)
|
1997-09-15 |
2003-04-15 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Thermal preactivation of gaseous precursor filled compositions
|
|
US6123923A
(en)
|
1997-12-18 |
2000-09-26 |
Imarx Pharmaceutical Corp. |
Optoacoustic contrast agents and methods for their use
|
|
US20010003580A1
(en)
|
1998-01-14 |
2001-06-14 |
Poh K. Hui |
Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
|
|
US6444192B1
(en)
|
1999-02-05 |
2002-09-03 |
The Regents Of The University Of California |
Diagnostic imaging of lymph structures
|
|
EP1202671A4
(en)
*
|
1999-08-13 |
2004-11-10 |
Point Biomedical Corp |
MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
|
|
EP1202670A4
(en)
*
|
1999-08-13 |
2004-11-10 |
Point Biomedical Corp |
HOLLOW MICROSPHERES WITH CONTROLLED FRAGILITY FOR MEDICAL USE
|
|
US6919068B2
(en)
*
|
2002-05-17 |
2005-07-19 |
Point Biomedical Corporation |
Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
|
|
US20030215394A1
(en)
*
|
2002-05-17 |
2003-11-20 |
Short Robert E. |
Microparticles having a matrix interior useful for ultrasound triggered delivery of drugs into the bloodstream
|
|
US20040185108A1
(en)
*
|
2003-03-18 |
2004-09-23 |
Short Robert E. |
Method of preparing gas-filled polymer matrix microparticles useful for delivering drug
|
|
US8012457B2
(en)
|
2004-06-04 |
2011-09-06 |
Acusphere, Inc. |
Ultrasound contrast agent dosage formulation
|
|
GB0811856D0
(en)
*
|
2008-06-27 |
2008-07-30 |
Ucl Business Plc |
Magnetic microbubbles, methods of preparing them and their uses
|
|
US8846063B2
(en)
|
2008-12-16 |
2014-09-30 |
Kimberly-Clark Worldwide, Inc. |
Personal care composition containing a volatile and a terpene alcohol
|
|
US10279053B2
(en)
|
2011-07-19 |
2019-05-07 |
Nuvox Pharma Llc |
Microbubble compositions, method of making same, and method using same
|
|
AU2015374286B2
(en)
|
2014-12-31 |
2021-11-18 |
Lantheus Medical Imaging, Inc. |
Lipid-encapsulated gas microsphere compositions and related methods
|
|
NL2014178B1
(en)
*
|
2015-01-22 |
2017-01-05 |
Tide Microfluidics B V |
System and method for controlled manufacturing of mono-disperse microbubbles.
|
|
IL262647B2
(en)
|
2016-05-04 |
2023-03-01 |
Lantheus Medical Imaging Inc |
Methods and devices for preparing sharpness factors for ultrasound
|
|
US9789210B1
(en)
|
2016-07-06 |
2017-10-17 |
Lantheus Medical Imaging, Inc. |
Methods for making ultrasound contrast agents
|
|
CN109568289B
(zh)
*
|
2017-09-28 |
2021-09-07 |
中国科学院深圳先进技术研究院 |
胎盘样硫酸软骨素a靶向传输系统及其制备方法和应用
|