ES2184812T3 - Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa. - Google Patents
Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa.Info
- Publication number
- ES2184812T3 ES2184812T3 ES95939157T ES95939157T ES2184812T3 ES 2184812 T3 ES2184812 T3 ES 2184812T3 ES 95939157 T ES95939157 T ES 95939157T ES 95939157 T ES95939157 T ES 95939157T ES 2184812 T3 ES2184812 T3 ES 2184812T3
- Authority
- ES
- Spain
- Prior art keywords
- steroids
- stabilized
- patterns
- chelators
- water solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 239000002738 chelating agent Substances 0.000 abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 2
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 238000010525 oxidative degradation reaction Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- -1 steroid compounds Chemical class 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
LAS SOLUCIONES ACUOSAS DE COMPUESTOS ESTEROIDEOS CON ACTIVIDAD BIOLOGICA Y CON TENDENCIA A LA DEGRADACION OXIDATIVA A TEMPERATURAS ENTRE 2 Y 8 (GRADOS) C DURANTE LA CONSERVACION EN EXCESO DE VARIOS MESES SE ESTABILIZAN MEDIANTE ADICION DE QUELANTES. SOLUCIONES ACUOSAS CON UN INTERES PARTICULAR SON SOLUCIONES CON PROTEINAS QUE SIMULAN EL COMPORTAMIENTO DE FLUIDOS CORPORALES HUMANOS COMO SUERO Y QUE POR LO TANTO SON ADECUADOS COMO ESTANDARES PARA INMUNOENSAYOS DE ESTEROIDES EN DICHOS FLUIDOS CORPORALES. TIENEN UN INTERES PARTICULAR LOS QUELANTES METALES DE TRANSICION, ESPECIALMENTE AQUELLOS QUE SECUESTRAN HIERRO EFICIENTEMENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34518194A | 1994-11-28 | 1994-11-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2184812T3 true ES2184812T3 (es) | 2003-04-16 |
Family
ID=23353908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95939157T Expired - Lifetime ES2184812T3 (es) | 1994-11-28 | 1995-11-13 | Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6767708B1 (es) |
| EP (1) | EP0795134B1 (es) |
| JP (1) | JP3560979B2 (es) |
| AT (1) | ATE223060T1 (es) |
| CA (1) | CA2204027C (es) |
| DE (1) | DE69527977T2 (es) |
| ES (1) | ES2184812T3 (es) |
| WO (1) | WO1996017252A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6797479B2 (en) * | 1995-04-04 | 2004-09-28 | Abbott Laboratories | Reagents and methods for the detection and quantification of vancomycin in biological fluids |
| US5699838A (en) | 1995-05-22 | 1997-12-23 | Inliner, U.S.A. | Apparatus for vacuum impregnation of a flexible, hollow tube |
| US20030215952A1 (en) * | 1998-10-02 | 2003-11-20 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US20030215359A1 (en) * | 1998-10-02 | 2003-11-20 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US7449338B2 (en) * | 1998-10-02 | 2008-11-11 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
| US20050142613A1 (en) * | 1998-10-02 | 2005-06-30 | David Bar-Or | Test for the rapid evaluation of ischemic states and kits |
| US7070937B1 (en) | 1998-10-02 | 2006-07-04 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| US6475743B1 (en) * | 1998-10-02 | 2002-11-05 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
| US20020137097A1 (en) * | 2000-12-13 | 2002-09-26 | Bio-Rad Laboratories, Inc. | Standard diluent for multiplex assays |
| US20040261816A1 (en) * | 2003-06-27 | 2004-12-30 | Brask Justin K. | Using bidentate chelators to clean semiconductor wafers |
| US20070141710A1 (en) * | 2005-12-20 | 2007-06-21 | Beckman Coulter, Inc. | Stable calibrators for immunoassays |
| DK2116241T3 (en) | 2007-01-26 | 2016-06-06 | Pola Pharma Inc | pharmaceutical composition |
| CN110579615A (zh) * | 2019-09-06 | 2019-12-17 | 广州科方生物技术股份有限公司 | 一种通用于血清中类固醇激素的释放剂及其制备方法 |
| CN117825476B (zh) * | 2024-01-10 | 2024-08-30 | 上海原科实业发展有限公司 | 一种血清蛋白电泳质控品及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3274062A (en) * | 1963-08-20 | 1966-09-20 | Hyland Lab | Diagnostic reagent |
| US4786606A (en) * | 1981-01-23 | 1988-11-22 | Baxter Travenol Laboratories, Inc. | Solid phase system for ligand assay |
| DE3122917A1 (de) * | 1981-06-10 | 1983-02-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Waessrige cholesterin-standardloesung und verfahren zu ihrer herstellung |
| US4432964A (en) * | 1981-08-24 | 1984-02-21 | Alza Corporation | Topical composition containing steroid in two forms released independently from polymeric carrier |
| US4344940A (en) * | 1981-11-30 | 1982-08-17 | E. R. Squibb & Sons, Inc. | Steroid formulation containing dipotassium EDTA |
| US4436738A (en) * | 1982-03-15 | 1984-03-13 | Mead Johnson & Company | Stabilized estradiol cream composition |
| US4672028A (en) * | 1984-05-23 | 1987-06-09 | Icn Micromedic Systems, Inc. | Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels |
| DE3445010A1 (de) * | 1984-12-10 | 1986-06-19 | Boehringer Mannheim Gmbh | Kontroll- bzw. eichserum fuer die lipid-diagnostik |
| US4707453A (en) * | 1985-04-05 | 1987-11-17 | Becton Dickinson And Company | Vesicle including a metal marker for use in an assay |
| GB8800078D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel antibodies |
| US5342760A (en) * | 1992-06-10 | 1994-08-30 | Abbott Laboratories | Determination of estradiol by competitive immunoassay |
| US5296377A (en) * | 1992-12-15 | 1994-03-22 | Boehringer Mannheim Corporation | Control reagent containing a hydroxylamine or an antioxidant |
-
1995
- 1995-11-13 JP JP51883496A patent/JP3560979B2/ja not_active Expired - Fee Related
- 1995-11-13 ES ES95939157T patent/ES2184812T3/es not_active Expired - Lifetime
- 1995-11-13 CA CA002204027A patent/CA2204027C/en not_active Expired - Fee Related
- 1995-11-13 AT AT95939157T patent/ATE223060T1/de not_active IP Right Cessation
- 1995-11-13 WO PCT/US1995/014845 patent/WO1996017252A1/en not_active Ceased
- 1995-11-13 DE DE69527977T patent/DE69527977T2/de not_active Expired - Lifetime
- 1995-11-13 EP EP95939157A patent/EP0795134B1/en not_active Expired - Lifetime
- 1995-12-08 US US08/569,886 patent/US6767708B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10512362A (ja) | 1998-11-24 |
| EP0795134A1 (en) | 1997-09-17 |
| CA2204027C (en) | 2006-03-14 |
| US6767708B1 (en) | 2004-07-27 |
| CA2204027A1 (en) | 1996-06-06 |
| DE69527977D1 (de) | 2002-10-02 |
| ATE223060T1 (de) | 2002-09-15 |
| DE69527977T2 (de) | 2003-05-08 |
| EP0795134B1 (en) | 2002-08-28 |
| WO1996017252A1 (en) | 1996-06-06 |
| JP3560979B2 (ja) | 2004-09-02 |
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