ES2184867T3 - Dispositivo de administracion por electro-transporte con circuito de sobrevoltaje. - Google Patents

Dispositivo de administracion por electro-transporte con circuito de sobrevoltaje.

Info

Publication number
ES2184867T3
ES2184867T3 ES96916910T ES96916910T ES2184867T3 ES 2184867 T3 ES2184867 T3 ES 2184867T3 ES 96916910 T ES96916910 T ES 96916910T ES 96916910 T ES96916910 T ES 96916910T ES 2184867 T3 ES2184867 T3 ES 2184867T3
Authority
ES
Spain
Prior art keywords
electro
administration device
overvoltage circuit
transport administration
voltage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96916910T
Other languages
English (en)
Inventor
Thomas A Riddle
Larry A Mcnichols
John D Badzinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2184867T3 publication Critical patent/ES2184867T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electronic Switches (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Basic Packing Technique (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Refuse Collection And Transfer (AREA)
  • Advancing Webs (AREA)
  • Medicinal Preparation (AREA)
  • Discharge Heating (AREA)
  • Surgical Instruments (AREA)
  • Amplifiers (AREA)
  • Dc-Dc Converters (AREA)
  • Generation Of Surge Voltage And Current (AREA)

Abstract

UN DISPOSITIVO DE ELECTROTRANSPORTE (10) PARA LA ADMINISTRACION DE AGENTES TERAPEUTICOS INCLUYE UN CONTROLADOR MULTIPLE ELEVADOR DE TENSION (100, 200), AJUSTABLE, PARA ELEVAR LA TENSION DE UNA FUENTE DE ALIMENTACION (102, 202) HASTA UNA TENSION DE TRABAJO V SUB,W} CUYO VALOR ES JUSTO EL SUFICIENTE PARA SUMINISTRAR EL NIVEL DE CORRIENTE TERAPEUTICO DESEADO I SUB,1} A TRAVES DE LOS ELECTRODOS (108, 112), DE LOS CUALES AL MENOS UNO CONTIENE EL AGENTE TERAPEUTICO QUE SE HA DE ADMINISTRAR.
ES96916910T 1995-06-02 1996-05-30 Dispositivo de administracion por electro-transporte con circuito de sobrevoltaje. Expired - Lifetime ES2184867T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46032295A 1995-06-02 1995-06-02

Publications (1)

Publication Number Publication Date
ES2184867T3 true ES2184867T3 (es) 2003-04-16

Family

ID=23828237

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96916910T Expired - Lifetime ES2184867T3 (es) 1995-06-02 1996-05-30 Dispositivo de administracion por electro-transporte con circuito de sobrevoltaje.

Country Status (18)

Country Link
US (4) US6035234A (es)
EP (1) EP0830176B1 (es)
JP (1) JPH11511677A (es)
KR (1) KR100454667B1 (es)
CN (1) CN1099300C (es)
AT (2) ATE225200T1 (es)
AU (1) AU700477B2 (es)
BE (1) BE1009518A5 (es)
CA (1) CA2217711C (es)
CH (1) CH690818A5 (es)
DE (2) DE19681422T1 (es)
DK (1) DK0830176T3 (es)
ES (1) ES2184867T3 (es)
IE (1) IE960312A1 (es)
MX (1) MX9709365A (es)
PT (1) PT830176E (es)
SE (1) SE520344C2 (es)
WO (1) WO1996038199A1 (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US5983133A (en) * 1997-09-29 1999-11-09 Becton, Dickinson And Company Iontophoresis system with voltage step-up circuit
WO1999030773A1 (en) * 1997-12-16 1999-06-24 Alza Corporation Regulator with artificial load to maintain regulated delivery
US7171264B1 (en) * 1999-05-10 2007-01-30 Genetronics, Inc. Intradermal delivery of active agents by needle-free injection and electroporation
US6520950B1 (en) * 1999-05-10 2003-02-18 Genetronics, Inc. Method of electroporation-enhanced delivery of active agents
US6385488B1 (en) * 1999-05-20 2002-05-07 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system
JP2001286569A (ja) * 2000-04-05 2001-10-16 Polytronics Ltd 経皮投薬装置
US6453195B1 (en) 2001-03-19 2002-09-17 Medtronic, Inc. Closed loop drug delivery system and remote management thereof
RU2286809C2 (ru) * 2001-04-27 2006-11-10 Байофоретик Терапьютик Систем, Ллс Способ и система электрокинетического ввода вещества
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US20040098065A1 (en) * 2002-11-19 2004-05-20 Alliance Health Products, Llc Transcutaneous nerve and muscle stimulator and method of using the same
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
JPWO2007010900A1 (ja) * 2005-07-15 2009-01-29 Ｔｔｉ・エルビュー株式会社 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置
ITMI20051356A1 (it) 2005-07-15 2007-01-16 Getters Spa Dispositivo getter per sistemi attivi per il rilascio transdermico di farmaci
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
WO2007026671A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. センサからの情報により投与すべき薬剤の選定を行うイオントフォレーシス装置
WO2007031973A2 (en) * 2005-09-15 2007-03-22 Visible Assets, Inc. Active low frequency radio tag and patch drug delivery system
KR20080047600A (ko) * 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
EP1928542A1 (en) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
US20090299265A1 (en) * 2005-09-30 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
EP1965858A2 (en) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System and method for remote based control of an iontophoresis device
EA023147B1 (ru) * 2006-04-13 2016-04-29 Тева Фармасьютикалс Интернешнл Гмбх Трансдермальный пластырь для лечения мигрени
WO2007132470A2 (en) * 2006-05-17 2007-11-22 Power Paper Ltd Constant current treatment device
USD576282S1 (en) 2006-06-16 2008-09-02 Activatek, Inc. Adhesive transdermal medicament patch
WO2008004204A1 (en) * 2006-07-06 2008-01-10 University Of Limerick An electrical stimulation device for nerves or muscles
US20080077076A1 (en) * 2006-08-29 2008-03-27 Transcutaneous Technologies Inc. Iontophoresis device and method for operation with a usb (universal serial bus) power source
CN101528300A (zh) * 2006-09-05 2009-09-09 Tti优而美株式会社 使用感应电源的透皮药物输送系统、装置和方法
US8728059B2 (en) * 2006-09-29 2014-05-20 Covidien Lp System and method for assuring validity of monitoring parameter in combination with a therapeutic device
KR20090106492A (ko) 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
US20080177219A1 (en) * 2007-01-23 2008-07-24 Joshi Ashok V Method for Iontophoretic Fluid Delivery
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8095213B1 (en) * 2007-05-31 2012-01-10 Purdue Pharma L.P. Transdermal patch
US7853320B1 (en) 2007-05-31 2010-12-14 Purdue Pharma L.P. Transdermal device having mechanical assist for porator-to-skin contact
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8047399B1 (en) 2007-07-05 2011-11-01 Purdue Pharma L.P. Dispenser for transdermal devices
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
US20100082219A1 (en) * 2008-09-30 2010-04-01 Gm Global Technology Operations, Inc. Engine Using Glow Plug Resistance For Estimating Combustion Temperature
WO2010078313A1 (en) * 2008-12-30 2010-07-08 Nupathe, Inc. Electronic control of drug delivery system
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US9008765B2 (en) * 2009-02-12 2015-04-14 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US8903485B2 (en) 2009-08-06 2014-12-02 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
CN105796533A (zh) * 2009-08-10 2016-07-27 泰华制药国际有限公司 用离子电渗疗法治疗恶心和偏头痛的方法
US20110087153A1 (en) * 2009-10-13 2011-04-14 Angelov Angel S Transdermal Methods And Systems For The Delivery Of Rizatriptan
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
WO2011100376A2 (en) 2010-02-10 2011-08-18 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
CN101829407B (zh) * 2010-05-14 2012-03-28 武汉海纳川科技有限公司 一种半导体激光血氧治疗仪
KR200457838Y1 (ko) 2010-05-27 2012-01-05 주식회사 가람아이앤씨 1.5볼트 전지의 아날로그 승압회로를 사용한 휴대용 피부 마사지기
CN101869739A (zh) * 2010-07-20 2010-10-27 段峰 一种自适应控制的皮肤表面电刺激装置及方法
AU2011332187B2 (en) 2010-11-23 2016-03-03 Teva Pharmaceuticals International Gmbh User-activated self-contained co-packaged iontophoretic drug delivery system
EP3626304A1 (en) 2011-03-24 2020-03-25 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
GB201414695D0 (en) * 2014-08-19 2014-10-01 Femeda Ltd Electrostimulation related devices and methods
US10463854B2 (en) 2015-02-24 2019-11-05 Elira, Inc. Systems and methods for managing symptoms associated with dysmenorrhea using an electro-dermal patch
JP2018050879A (ja) * 2016-09-28 2018-04-05 株式会社大島製作所 電気的刺激装置
USD821593S1 (en) * 2016-11-23 2018-06-26 Elira, Inc. Electro-dermal patch for use as a medical device
DK3804823T3 (da) * 2017-11-28 2023-07-24 West & Bergh Holding Ab Forbedret bevægelsestræningshjælp med stimulator
US11251635B2 (en) 2017-12-19 2022-02-15 Welch Allyn, Inc. Vital signs monitor with a removable and dischargable battery
WO2020087270A1 (zh) * 2018-10-30 2020-05-07 深圳市锐明技术股份有限公司 一种用于车载设备的断电保护电路、装置及系统
KR102353059B1 (ko) * 2020-04-13 2022-01-20 주식회사 아이센스 생체정보의 측정장치
US11994886B2 (en) * 2021-12-17 2024-05-28 ONiO AS Power saving in an embedded system

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR558409A (fr) * 1922-11-08 1923-08-27 équerre à niveau d'eau
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4019510A (en) * 1975-02-10 1977-04-26 Sybron Corporation Therapeutic method of using low intensity direct current generator with polarity reversal
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
JPS5347192A (en) * 1976-10-13 1978-04-27 Matsushita Electric Industrial Co Ltd Device for introducing fluorine ion to tooth
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4301794A (en) * 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
BR8008859A (pt) * 1979-10-10 1981-08-25 Cyclotech Med Ind Bandagem bloqueadora de dor
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
DE3137384A1 (de) * 1981-09-19 1983-04-07 Bayer Ag, 5090 Leverkusen Flockungsstabile mischphasenpigmente mit rutilstruktur, verfahren zu ihrer herstellung sowie ihre verwendung
US4457748A (en) * 1982-01-11 1984-07-03 Medtronic, Inc. Non-invasive diagnosis method
US4456012A (en) * 1982-02-22 1984-06-26 Medtronic, Inc. Iontophoretic and electrical tissue stimulation device
EP0092015A1 (fr) * 1982-04-16 1983-10-26 Roland Brodard Dispositif d'ionisation
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US5224928A (en) * 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
EP0308572B1 (en) * 1983-09-01 1995-11-08 Hisamitsu Pharmaceutical Co., Inc. An iontophoresis device
US4855243A (en) * 1983-09-26 1989-08-08 H.S.G. Venture (A Joint Venture Partnership) Neurological and biological molecular electro-optical devices and methods
JPS6222662A (ja) * 1985-07-19 1987-01-30 林原　健 イオン導入電子治療器
JPS62139672A (ja) * 1985-12-14 1987-06-23 林原　健 正負イオントホレ−ゼ用治療器
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5250022A (en) * 1990-09-25 1993-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
JPS63145669A (ja) * 1986-10-11 1988-06-17 林原　健 正、負イオントホレ−ゼ用スイッチ
US4786277A (en) * 1986-11-21 1988-11-22 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
FR2607708B3 (fr) * 1986-12-05 1989-02-24 Bontemps Raymond Dispositif destine au transfert sous-cutane de substances medicinales
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US5312325A (en) * 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
US5013293A (en) * 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4866442A (en) * 1987-06-01 1989-09-12 Steim Joseph M Analog to digital converter employing delta-sigma modulation
US4764168A (en) * 1987-08-28 1988-08-16 Suh Ku W Tympanic membrane implant
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US4997418A (en) * 1988-04-21 1991-03-05 C. P. Chambers Epidermal iontophoresis device
GB2219210A (en) * 1988-05-31 1989-12-06 S G Daniel Apparatus for modulating electro-dynamic fields associated with living tissue
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5135478A (en) * 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
CA2071321C (en) * 1989-05-10 2000-12-12 Dan Sibalis Multi-signal electrical transdermal drug applicator
JPH0366384A (ja) * 1989-08-04 1991-03-22 Senjiyu Seiyaku Kk 生理活性物質放出制御システム
JP2513930B2 (ja) * 1989-10-12 1996-07-10 シーメンス アクチエンゲゼルシヤフト フィルタプラグコネクタ
AU647109B2 (en) * 1989-10-23 1994-03-17 Theratech, Inc.(Incorporated under the laws of the State of Delaware) Iontophoresis device and method using a rate-controlling membrane
IT1244030B (it) * 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
DE4028125A1 (de) * 1990-01-17 1991-07-18 Klimke Markus Applikationsvorrichtung fuer die geregelte dosierung verschiedener pharmakons mittels elektrischem strom zum perkutanen transport zur lokalen und systemischen therapie
US5207752A (en) * 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
DK0522043T3 (da) * 1990-03-30 2004-02-23 Alza Corp Iontoforetisk indgivelsesindretning
WO1991015261A1 (en) * 1990-03-30 1991-10-17 Medtronic, Inc. Activity controlled electrotransport drug delivery device
US5213568A (en) * 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
CA2081896A1 (en) * 1990-06-15 1991-12-16 James E. Shapland Drug delivery apparatus and method
US5160316A (en) * 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5224927A (en) * 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5254081A (en) * 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5169384A (en) * 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
CA2122150A1 (en) * 1991-08-26 1993-03-04 Yie W. Chien Iontotherapeutic device and process
MX9206990A (es) * 1991-12-03 1993-06-01 Alza Corp Dispositivo iontoforetico de surtido y suministro de energia para el mismo.
CA2084734C (en) * 1991-12-17 1998-12-01 John L. Haynes Iontophoresis system having features for reducing skin irritation
US5256137A (en) * 1992-03-10 1993-10-26 Becton Dickinson And Company Biphasic power source for use in an iontophoretic drug delivery system
US5246418A (en) * 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
US5499967A (en) * 1992-02-27 1996-03-19 Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) Transdermal drug delivery device with waveshape generator
FR2688106B1 (fr) * 1992-02-27 1994-09-09 Lhd Lab Hygiene Dietetique Dispositif de generation d'une tension electrique de forme d'onde predeterminee, appareil ionophoretique d'administration transdermique de medicaments.
GB2265088B (en) 1992-03-10 1996-02-07 Kyosti Eero Antero Kontturi Electrochemical device for drug delivery
US5189307A (en) * 1992-03-13 1993-02-23 Empi, Inc. Isolated current mirror with optical insulator generating feedback signal
US5306235A (en) * 1992-09-30 1994-04-26 Becton Dickinson And Company Failsafe iontophoresis drug delivery system
US5533971A (en) 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
US5540654A (en) 1994-09-02 1996-07-30 North Carolina State University Iontophoretic electrode
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5879322A (en) 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
IE960312A1 (en) 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
DE122006000022I1 (de) 1995-06-05 2006-09-21 Alza Corp Vorrichtung zur Transdermalen iontophoretischen verabreichung von Fentanyl und Sufentanil
US6167301A (en) * 1995-08-29 2000-12-26 Flower; Ronald J. Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
EP0847775B1 (en) 1995-08-31 2004-10-27 Hisamitsu Pharmaceutical Co. Inc. Iontophoresis device and method of current control therefor
FR2755842B1 (fr) 1996-11-19 1999-04-23 Lhd Lab Hygiene Dietetique Procede de mesure de la resistance electrique cutanee d'un patient soumis a une administration transdermique de medicament
WO1999030773A1 (en) 1997-12-16 1999-06-24 Alza Corporation Regulator with artificial load to maintain regulated delivery
JP2001286569A (ja) 2000-04-05 2001-10-16 Polytronics Ltd 経皮投薬装置

Also Published As

Publication number Publication date
AT408616B (de) 2002-01-25
DE19681422T1 (de) 1998-05-20
CN1099300C (zh) 2003-01-22
CA2217711C (en) 2009-05-19
EP0830176B1 (en) 2002-10-02
JPH11511677A (ja) 1999-10-12
DK0830176T3 (da) 2003-02-03
KR100454667B1 (ko) 2005-01-17
SE520344C2 (sv) 2003-07-01
US20020087193A1 (en) 2002-07-04
CH690818A5 (de) 2001-01-31
SE9704478D0 (sv) 1997-12-02
EP0830176A1 (en) 1998-03-25
MX9709365A (es) 1998-02-28
US6842640B2 (en) 2005-01-11
SE9704478L (sv) 1997-12-02
CN1186449A (zh) 1998-07-01
AU700477B2 (en) 1999-01-07
WO1996038199A1 (en) 1996-12-05
DE69624109D1 (de) 2002-11-07
IE960312A1 (en) 1996-12-11
DE69624109T2 (de) 2003-06-18
US20030018296A1 (en) 2003-01-23
US6035234A (en) 2000-03-07
CA2217711A1 (en) 1996-12-05
KR19990014954A (ko) 1999-02-25
ATA903496A (de) 2001-06-15
ATE225200T1 (de) 2002-10-15
US7708731B2 (en) 2010-05-04
US20050075623A1 (en) 2005-04-07
AU5963096A (en) 1996-12-18
PT830176E (pt) 2003-02-28
BE1009518A5 (fr) 1997-04-01

Similar Documents

Publication Publication Date Title
ES2184867T3 (es) Dispositivo de administracion por electro-transporte con circuito de sobrevoltaje.
AR017439A1 (es) Medios de suministro, disposicion de suministro, dispositivo de suministro y metodo para suministrar a la region posterior de la cavidad nasal liquidoconteniendo medicamento
BR9808547A (pt) Fornecimento de energia de modo de comutação com proteção contra corrente excessiva
ES2117249T3 (es) Derivados de 2,6-diaminopurina.
ES2141956T3 (es) Metodos y aparato para el suministro de composiciones medicamentosas solidas.
DE69214158D1 (de) Iontophoretische verbreichungsvorrichtung und versorgungsnetz dafür
ATE295010T1 (de) Leistungspulsanordnung mit hoher pulsrate, kurzer anstiegszeit und niedrigem leckstrom
KR930700181A (ko) 2단계 전달 프로파일을 갖는 전리요법적 약물 전달계
CO5060481A1 (es) Suministro de agente activo aerosolizado modulado con resistencia de flujo
BR9609245A (pt) Método e aparelho para distribuição de agente por meio de eletrotransporte
DK190687A (da) Apparat til elektrostatisk sproejtning
ES2112341T3 (es) Dispositivo de soplete de plasma, por ejemplo para procesos quimicos.
ES2108837T3 (es) Dispositivo de iontoforesis para la administracion transcutanea de una cantidad total dada de un principio activo a un sujeto.
ES2094622T3 (es) Derivados triterpenos y antagonistas del receptor de endotelina que los contiene.
BR9100100A (pt) Dispositivo para realizar uma iontoforese intracorporea e cateter para uso na mesma
RU2567462C2 (ru) Защита от перенапряжения для дефибриллятора
ES2124256T3 (es) Arilmorfolina, preparacion y uso.
DE69408772D1 (de) Halbleitervorrichtung mit schnellen lateralem DMOST mit Hochspannungs-Sourceelektrode
ES2132651T3 (es) Derivados amidicos de la vitamina d.
ES2090415T3 (es) Disposicion de circuito para la limitacion de la corriente de conexion y para la proteccion contra la sobretension en aparatos de alimentacion de corriente sincronizados.
ES8703054A1 (es) Dispositivo de mando susceptible de garantizar una fuerte cresta de corriente de llamada
ES2136141T3 (es) Implante dental.
ES2113616T3 (es) Aparato de bombeo de combustible.
ES2079086T3 (es) Un conjunto para controlar un dispositivo alimentador de impulsos de tension en un precipitador electrostatico.
ES8707388A1 (es) Circuito de control de polarizacion y circuito de supresion de arco para dispositivos bimetalicos de control