ES2185003T3 - Procedimiento para la desintegracion de acidos nucleicos en materiales biologicamente activos. - Google Patents

Procedimiento para la desintegracion de acidos nucleicos en materiales biologicamente activos.

Info

Publication number
ES2185003T3
ES2185003T3 ES97915196T ES97915196T ES2185003T3 ES 2185003 T3 ES2185003 T3 ES 2185003T3 ES 97915196 T ES97915196 T ES 97915196T ES 97915196 T ES97915196 T ES 97915196T ES 2185003 T3 ES2185003 T3 ES 2185003T3
Authority
ES
Spain
Prior art keywords
disintegration
procedure
biologically active
nucleic acids
active materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97915196T
Other languages
English (en)
Inventor
Friedrich Dorner
Noel Barrett
Johann Eibl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter AG
Original Assignee
Baxter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter AG filed Critical Baxter AG
Application granted granted Critical
Publication of ES2185003T3 publication Critical patent/ES2185003T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA DESINTEGRACION DE UN ACIDO NUCLEICO BIOLOGICAMENTE ACTIVO QUE SE ENCUENTRA EN UN MATERIAL BIOLOGICO, EXPONIENDOSE EL MATERIAL BIOLOGICO QUE ES ACTIVO UNA O VARIAS VECES A UNA RADIACION LASER, PARA DESINTEGRAR TODOS LOS ACIDOS NUCLEICOS BIOLOGICAMENTE ACTIVOS QUE SE ENCUENTRAN EN ESTE MATERIAL BIOLOGICO, CONSERVANDO LA INTEGRIDAD Y ACTIVIDAD BIOLOGICA DEL MATERIAL BIOLOGICO.
ES97915196T 1996-04-09 1997-04-08 Procedimiento para la desintegracion de acidos nucleicos en materiales biologicamente activos. Expired - Lifetime ES2185003T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0062996A AT406778B (de) 1996-04-09 1996-04-09 Verfahren zur desintegration von nucleinsäuren und herstellung von qualitätsgesicherten biologischen produkten

Publications (1)

Publication Number Publication Date
ES2185003T3 true ES2185003T3 (es) 2003-04-16

Family

ID=3495662

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97915196T Expired - Lifetime ES2185003T3 (es) 1996-04-09 1997-04-08 Procedimiento para la desintegracion de acidos nucleicos en materiales biologicamente activos.

Country Status (6)

Country Link
US (1) US6165711A (es)
EP (1) EP0900087B1 (es)
AT (2) AT406778B (es)
DE (1) DE59708441D1 (es)
ES (1) ES2185003T3 (es)
WO (1) WO1997037686A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7900435A (nl) * 1979-01-19 1980-07-22 Doornes Transmissie Bv Samengestelde drijfriem met dwarselementen voorzien van onderlinge koppelingsmiddelen.
NL7900923A (nl) * 1979-02-06 1980-08-08 Doornes Transmissie Bv Samengestelde drijfriem voorzien van dwarselementen met koppelingsmiddelen, en dwarselement voor een drijfriem.
US4365965A (en) * 1980-09-08 1982-12-28 The Gates Rubber Company V-Block belt
US7186543B1 (en) * 1998-07-21 2007-03-06 Gambro Inc. Preparation of vaccines using a photosensitizer and light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US6843961B2 (en) 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US20020176796A1 (en) * 2000-06-20 2002-11-28 Purepulse Technologies, Inc. Inactivation of microbes in biological fluids
FR2810549A1 (fr) * 2000-06-27 2001-12-28 Laurent Galey Composition presentant une activite antiparasitaire et biologique
US20030030011A1 (en) * 2001-05-17 2003-02-13 Purepulse Technologies, Inc. Light treatment control in a fluid treatment system using light for the treatment of fluid products
US20030060747A1 (en) * 2001-05-17 2003-03-27 Fries William M. Fluid flow path for a fluid treatment system using light for the decontamination of fluid products
CN102026645B (zh) 2006-09-15 2016-01-27 渥太华医院研究机构 溶瘤弹状病毒
US20140127077A1 (en) 2012-11-05 2014-05-08 Gail Rock Device and method for sterilization of instruments and surfaces
ES2762154T3 (es) 2013-03-15 2020-05-22 Dsm Ip Assets Bv Uso de nucleasas termófilas para degradar ácidos nucleicos
CN110115761B (zh) * 2019-05-09 2023-06-16 英诺激光科技股份有限公司 一种利用激光和载体技术制备疫苗的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880512A (en) * 1984-02-16 1989-11-14 Kollmorgen Corporation Pulsed light selective photolysis process for treatment of biological media and products made thereby
AU3849685A (en) * 1984-02-16 1985-08-22 Molecular Biophysics Technology, Inc. Pusled light selective photcysis for sterilization of biological fluid
JPS61275228A (ja) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド 治療用タンパク組成物中のビ−ルスの光動的不活性化
AT389889B (de) * 1988-05-03 1990-02-12 Langenecker Bertwin Dr Verfahren und vorrichtung zum inaktivieren von in einem traegermedium enthaltenen viren
US5571666A (en) * 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
US4950665A (en) * 1988-10-28 1990-08-21 Oklahoma Medical Research Foundation Phototherapy using methylene blue
ATE143596T1 (de) * 1989-05-11 1996-10-15 Oklahoma Med Res Found Antivirale therapie unter verwendung von thiazin- und xanthenfarbstoffen
DE3930510A1 (de) * 1989-09-13 1991-03-21 Blutspendedienst Dt Rote Kreuz Verfahren zur inaktivierung von viren in blut und blutprodukten
WO1991016911A1 (en) * 1990-05-01 1991-11-14 The American National Red Cross Decontamination of whole blood and cellular components by phenthiazin-5-ium-dyes plus light
JPH04131085A (ja) * 1990-09-19 1992-05-01 Hitachi Ltd レーザーを用いる細胞の変異株の取得方法
DE4403798A1 (de) * 1994-02-03 1995-08-10 Fouad Dipl Ing Khalil Verfahren zur Sterilisation des Blutes durch ultraviolette Strahlung, um alle Viren im Blut, insbesondere den HIV-Virus und Hepatitisvirus, abzutöten (Ziel ist es, diesen Virus im Blut ganz abzutöten)
US5494243A (en) * 1994-05-25 1996-02-27 Abc Rail Products Corporation Railroad switch stand with foot operated handle latch
CA2159044A1 (en) * 1994-09-26 1996-03-27 Falko-Guenter Falkner Method of quantitating nucleic acids
US5663043A (en) * 1995-01-04 1997-09-02 Hemasure Inc. Method for inactivating non-enveloped viruses using a viricide-potentiating agent with a photoactivatible virucide

Also Published As

Publication number Publication date
EP0900087A1 (de) 1999-03-10
EP0900087B1 (de) 2002-10-09
US6165711A (en) 2000-12-26
ATA62996A (de) 2000-01-15
WO1997037686A1 (de) 1997-10-16
DE59708441D1 (de) 2002-11-14
ATE225669T1 (de) 2002-10-15
AT406778B (de) 2000-09-25

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