ES2185654T3 - Sistema para la administracion de farmacos. - Google Patents
Sistema para la administracion de farmacos.Info
- Publication number
- ES2185654T3 ES2185654T3 ES94918945T ES94918945T ES2185654T3 ES 2185654 T3 ES2185654 T3 ES 2185654T3 ES 94918945 T ES94918945 T ES 94918945T ES 94918945 T ES94918945 T ES 94918945T ES 2185654 T3 ES2185654 T3 ES 2185654T3
- Authority
- ES
- Spain
- Prior art keywords
- matrix
- administration
- pharmaco
- environment
- receiver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011159 matrix material Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000003100 immobilizing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE PRESENTA UN METODO PARA LA PRODUCCION DE UN SISTEMA PARA LA ADMINISTRACION DE UN FARMACO PARA EL TRATAMIENTO DE UN ESTADO, QUE CONSISTE EN INMOVILIZAR UN FARMACO U OTRO AGENTE EN UNA MATRIZ BIOCOMPATIBLES QUE CONTENGA AL MENOS UN RECEPTOR PARA UNA SUSTANCIA FISIOLOGICA QUE SE ENCONTRARA EN EL ENTORNO DE LA MATRIZ CUANDO SE ADMINISTRE, DON DONDE DICHO RECEPTOR SE UNE DENTRO DE LA MATRIZ PERO PERMANECE BIOLOGICAMENTE ACTIVO ACTIVANDOSE EN RESPUESTA A LOS NIVELES DE DICHA SUSTANCIA FISIOLOGICA PARA REALIZAR UN CAMBIO CONFORMACIONAL EN LA MATRIZ PERMITIENDO LA MOVILIZACION Y LIBERACION DEL FARMACO UNICAMENTE EN EL ENTORNO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939313484A GB9313484D0 (en) | 1993-06-30 | 1993-06-30 | Drug system ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2185654T3 true ES2185654T3 (es) | 2003-05-01 |
Family
ID=10738039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94918945T Expired - Lifetime ES2185654T3 (es) | 1993-06-30 | 1994-06-27 | Sistema para la administracion de farmacos. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5902607A (es) |
| EP (1) | EP0706401B1 (es) |
| JP (1) | JP4572008B2 (es) |
| AT (1) | ATE228374T1 (es) |
| AU (1) | AU7004194A (es) |
| DE (1) | DE69431800T2 (es) |
| DK (1) | DK0706401T3 (es) |
| ES (1) | ES2185654T3 (es) |
| GB (1) | GB9313484D0 (es) |
| PT (1) | PT706401E (es) |
| WO (1) | WO1995001186A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9200638D0 (en) * | 1992-01-10 | 1992-03-11 | Leicester Polytechnic | Drug system |
| GB0116860D0 (en) * | 2001-07-10 | 2001-09-05 | Univ Montfort | Gel compositions |
| AU2003301064A1 (en) | 2002-12-17 | 2004-07-14 | Massachusetts Institute Of Technology | Stimuli-responsive systems for controlled drug delivery |
| GB0412631D0 (en) * | 2004-06-07 | 2004-07-07 | Cambridge Applied Polymers Ltd | Polymer release system |
| JP5296531B2 (ja) | 2005-05-05 | 2013-09-25 | センシエント フレイバーズ エルエルシー | βグルカン及びマンナンの製造 |
| US7687608B2 (en) * | 2005-10-19 | 2010-03-30 | Smartcells, Inc. | Methods for reducing the mitogenicity of lectin compositions |
| WO2008079897A2 (en) * | 2006-12-22 | 2008-07-03 | The Regents Of The University Of California | Macromolecular conjugates of cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof |
| KR101635689B1 (ko) | 2009-01-28 | 2016-07-01 | 스마트쎌스, 인크. | 제어 약물 전달을 위한 접합체 기재 시스템 |
| WO2010088286A1 (en) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Synthetic conjugates and uses thereof |
| CA2750223A1 (en) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Exogenously triggered controlled release materials and uses thereof |
| US8906850B2 (en) | 2009-01-28 | 2014-12-09 | Smartcells, Inc. | Crystalline insulin-conjugates |
| EP2391380A4 (en) * | 2009-01-28 | 2015-05-13 | Smartcells Inc | NETWORKED MATERIALS ON POLYNUCLEOTIDE ADAPTASE BASE AND APPLICATIONS THEREOF |
| US9095623B2 (en) * | 2009-03-20 | 2015-08-04 | Smartcells, Inc. | Terminally-functionalized conjugates and uses thereof |
| EP2408808A4 (en) | 2009-03-20 | 2015-05-06 | Smartcells Inc | TERMINAL-FUNCTIONALIZED CONJUGATES AND THEIR USE |
| US8569231B2 (en) | 2009-03-20 | 2013-10-29 | Smartcells, Inc. | Soluble non-depot insulin conjugates and uses thereof |
| EP2598522A4 (en) | 2010-07-28 | 2014-11-12 | Smartcells Inc | RECOMBINANT LKTINE, BINDING POINT MODIFIED LECTIN AND APPLICATIONS THEREOF |
| WO2012015692A2 (en) | 2010-07-28 | 2012-02-02 | Smartcells, Inc. | Recombinantly expressed insulin polypeptides and uses thereof |
| AU2011282977A1 (en) | 2010-07-28 | 2013-02-21 | Smartcells, Inc. | Drug-ligand conjugates, synthesis thereof, and intermediates thereto |
| WO2013123491A1 (en) * | 2012-02-17 | 2013-08-22 | Massachusetts Institute Of Technology | Self-regulated peptide hydrogel for insulin delivery |
| GB201310185D0 (en) | 2013-06-07 | 2013-07-24 | Univ Montfort | Container |
| GB201314640D0 (en) | 2013-08-15 | 2013-10-02 | Univ Montfort | Matrix gel |
| TW201605470A (zh) | 2013-10-04 | 2016-02-16 | 默沙東藥廠 | 葡萄糖反應性胰島素結合物 |
| WO2018175272A1 (en) | 2017-03-23 | 2018-09-27 | Merck Sharp & Dohme Corp. | Glucose responsive insulin comprising a tri-valent sugar cluster for treatment of diabetes |
| EP3727424A4 (en) | 2017-12-18 | 2021-10-27 | Merck Sharp & Dohme Corp. | CONJUGATE-BASED SYSTEMS FOR CONTROLLED INSULIN RELEASE |
| US11413352B2 (en) | 2017-12-18 | 2022-08-16 | Merck, Sharp & Dohme LLC | Conjugate based systems for controlled insulin delivery |
| CN108721605B (zh) * | 2018-06-01 | 2022-10-14 | 华南师范大学 | 一种装载有胰岛素的纳米粒子及其应用 |
| US20230010871A1 (en) * | 2019-12-13 | 2023-01-12 | Folium Labs Inc. | Complexes comprising a carbohydrate polymer and an active ingredient and processes for their preparation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4348387A (en) * | 1979-07-31 | 1982-09-07 | The Rockefeller University | Method and system for the controlled release of biologically active substances to a body fluid |
| CA2084194C (en) * | 1991-04-02 | 2003-05-20 | Gregory John Russell-Jones | Oral delivery systems for microparticles |
| GB9200638D0 (en) * | 1992-01-10 | 1992-03-11 | Leicester Polytechnic | Drug system |
-
1993
- 1993-06-30 GB GB939313484A patent/GB9313484D0/en active Pending
-
1994
- 1994-06-27 DK DK94918945T patent/DK0706401T3/da active
- 1994-06-27 AU AU70041/94A patent/AU7004194A/en not_active Abandoned
- 1994-06-27 EP EP94918945A patent/EP0706401B1/en not_active Expired - Lifetime
- 1994-06-27 AT AT94918945T patent/ATE228374T1/de active
- 1994-06-27 US US08/569,119 patent/US5902607A/en not_active Expired - Lifetime
- 1994-06-27 PT PT94918945T patent/PT706401E/pt unknown
- 1994-06-27 JP JP50334595A patent/JP4572008B2/ja not_active Expired - Fee Related
- 1994-06-27 DE DE69431800T patent/DE69431800T2/de not_active Expired - Lifetime
- 1994-06-27 WO PCT/GB1994/001384 patent/WO1995001186A1/en not_active Ceased
- 1994-06-27 ES ES94918945T patent/ES2185654T3/es not_active Expired - Lifetime
-
1998
- 1998-07-29 US US09/124,445 patent/US6410053B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69431800T2 (de) | 2003-09-04 |
| GB9313484D0 (en) | 1993-08-11 |
| DK0706401T3 (da) | 2003-03-03 |
| EP0706401A1 (en) | 1996-04-17 |
| US6410053B1 (en) | 2002-06-25 |
| EP0706401B1 (en) | 2002-11-27 |
| WO1995001186A1 (en) | 1995-01-12 |
| PT706401E (pt) | 2003-03-31 |
| JPH09501416A (ja) | 1997-02-10 |
| JP4572008B2 (ja) | 2010-10-27 |
| US5902607A (en) | 1999-05-11 |
| DE69431800D1 (de) | 2003-01-09 |
| AU7004194A (en) | 1995-01-24 |
| ATE228374T1 (de) | 2002-12-15 |
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