ES2185654T3 - Sistema para la administracion de farmacos. - Google Patents

Sistema para la administracion de farmacos.

Info

Publication number
ES2185654T3
ES2185654T3 ES94918945T ES94918945T ES2185654T3 ES 2185654 T3 ES2185654 T3 ES 2185654T3 ES 94918945 T ES94918945 T ES 94918945T ES 94918945 T ES94918945 T ES 94918945T ES 2185654 T3 ES2185654 T3 ES 2185654T3
Authority
ES
Spain
Prior art keywords
matrix
administration
pharmaco
environment
receiver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94918945T
Other languages
English (en)
Inventor
Margaret Joan Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
De Montfort University
Original Assignee
De Montfort University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Montfort University filed Critical De Montfort University
Application granted granted Critical
Publication of ES2185654T3 publication Critical patent/ES2185654T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PRESENTA UN METODO PARA LA PRODUCCION DE UN SISTEMA PARA LA ADMINISTRACION DE UN FARMACO PARA EL TRATAMIENTO DE UN ESTADO, QUE CONSISTE EN INMOVILIZAR UN FARMACO U OTRO AGENTE EN UNA MATRIZ BIOCOMPATIBLES QUE CONTENGA AL MENOS UN RECEPTOR PARA UNA SUSTANCIA FISIOLOGICA QUE SE ENCONTRARA EN EL ENTORNO DE LA MATRIZ CUANDO SE ADMINISTRE, DON DONDE DICHO RECEPTOR SE UNE DENTRO DE LA MATRIZ PERO PERMANECE BIOLOGICAMENTE ACTIVO ACTIVANDOSE EN RESPUESTA A LOS NIVELES DE DICHA SUSTANCIA FISIOLOGICA PARA REALIZAR UN CAMBIO CONFORMACIONAL EN LA MATRIZ PERMITIENDO LA MOVILIZACION Y LIBERACION DEL FARMACO UNICAMENTE EN EL ENTORNO.
ES94918945T 1993-06-30 1994-06-27 Sistema para la administracion de farmacos. Expired - Lifetime ES2185654T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939313484A GB9313484D0 (en) 1993-06-30 1993-06-30 Drug system ii

Publications (1)

Publication Number Publication Date
ES2185654T3 true ES2185654T3 (es) 2003-05-01

Family

ID=10738039

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94918945T Expired - Lifetime ES2185654T3 (es) 1993-06-30 1994-06-27 Sistema para la administracion de farmacos.

Country Status (11)

Country Link
US (2) US5902607A (es)
EP (1) EP0706401B1 (es)
JP (1) JP4572008B2 (es)
AT (1) ATE228374T1 (es)
AU (1) AU7004194A (es)
DE (1) DE69431800T2 (es)
DK (1) DK0706401T3 (es)
ES (1) ES2185654T3 (es)
GB (1) GB9313484D0 (es)
PT (1) PT706401E (es)
WO (1) WO1995001186A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200638D0 (en) * 1992-01-10 1992-03-11 Leicester Polytechnic Drug system
GB0116860D0 (en) * 2001-07-10 2001-09-05 Univ Montfort Gel compositions
CA2509382A1 (en) 2002-12-17 2004-07-08 Todd C. Zion Stimuli-responsive systems for controlled drug delivery
GB0412631D0 (en) * 2004-06-07 2004-07-07 Cambridge Applied Polymers Ltd Polymer release system
MX2007013725A (es) 2005-05-05 2008-04-09 Sensient Flavors Inc Produccion de beta-glucanos y mananos.
US7687608B2 (en) 2005-10-19 2010-03-30 Smartcells, Inc. Methods for reducing the mitogenicity of lectin compositions
EP2117601A2 (en) * 2006-12-22 2009-11-18 The Regents of the University of California Macromolecular conjugates of cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof
WO2010088276A2 (en) * 2009-01-28 2010-08-05 Smartcells, Inc. Polynucleotide aptamer-based cross -linked materials and uses thereof
BRPI1007457A2 (pt) 2009-01-28 2015-08-25 Smartcells Inc Conjungado, formulação de liberação prolongada, e, sistema de distribuição de bomba.
WO2010088268A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
WO2010088286A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Synthetic conjugates and uses thereof
WO2010088300A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Crystalline insulin-conjugates
US9095623B2 (en) * 2009-03-20 2015-08-04 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
US8623345B2 (en) 2009-03-20 2014-01-07 Smartcells Terminally-functionalized conjugates and uses thereof
WO2010107520A1 (en) 2009-03-20 2010-09-23 Smartcells, Inc. Soluble non-depot insulin conjugates and uses thereof
EP2598522A4 (en) 2010-07-28 2014-11-12 Smartcells Inc RECOMBINANT LKTINE, BINDING POINT MODIFIED LECTIN AND APPLICATIONS THEREOF
AU2011282977A1 (en) 2010-07-28 2013-02-21 Smartcells, Inc. Drug-ligand conjugates, synthesis thereof, and intermediates thereto
JP2013535467A (ja) 2010-07-28 2013-09-12 スマートセルズ・インコーポレイテツド 組換えにより発現されたインスリンポリペプチドおよびその使用
US9994615B2 (en) * 2012-02-17 2018-06-12 Massachusetts Institute Of Technology Self-regulated peptide hydrogel for insulin delivery
GB201310185D0 (en) 2013-06-07 2013-07-24 Univ Montfort Container
GB201314640D0 (en) 2013-08-15 2013-10-02 Univ Montfort Matrix gel
KR20160065930A (ko) 2013-10-04 2016-06-09 머크 샤프 앤드 돔 코포레이션 글루코스-반응성 인슐린 접합체
WO2018175272A1 (en) 2017-03-23 2018-09-27 Merck Sharp & Dohme Corp. Glucose responsive insulin comprising a tri-valent sugar cluster for treatment of diabetes
US11413352B2 (en) 2017-12-18 2022-08-16 Merck, Sharp & Dohme LLC Conjugate based systems for controlled insulin delivery
EP3727424A4 (en) 2017-12-18 2021-10-27 Merck Sharp & Dohme Corp. CONJUGATE-BASED SYSTEMS FOR CONTROLLED INSULIN RELEASE
CN108721605B (zh) * 2018-06-01 2022-10-14 华南师范大学 一种装载有胰岛素的纳米粒子及其应用
EP4072590A4 (en) * 2019-12-13 2024-01-03 Folium Labs Inc. COMPLEXES COMPRISING A CARBOHYDRATE POLYMER AND AN ACTIVE INGREDIENT AND THEIR PREPARATION PROCESSES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348387A (en) * 1979-07-31 1982-09-07 The Rockefeller University Method and system for the controlled release of biologically active substances to a body fluid
HK1002252A1 (en) * 1991-04-02 1998-08-07 Biotech Australia Pty. Limited Oral delivery systems for microparticles
GB9200638D0 (en) * 1992-01-10 1992-03-11 Leicester Polytechnic Drug system

Also Published As

Publication number Publication date
US6410053B1 (en) 2002-06-25
WO1995001186A1 (en) 1995-01-12
DE69431800D1 (de) 2003-01-09
ATE228374T1 (de) 2002-12-15
AU7004194A (en) 1995-01-24
JP4572008B2 (ja) 2010-10-27
DK0706401T3 (da) 2003-03-03
US5902607A (en) 1999-05-11
EP0706401B1 (en) 2002-11-27
JPH09501416A (ja) 1997-02-10
DE69431800T2 (de) 2003-09-04
GB9313484D0 (en) 1993-08-11
PT706401E (pt) 2003-03-31
EP0706401A1 (en) 1996-04-17

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