ES2187203T3 - Sistema conservante para composiciones farmaceuticas administrables topicamente que contiene un jabon de acido graso/aminoacido. - Google Patents

Sistema conservante para composiciones farmaceuticas administrables topicamente que contiene un jabon de acido graso/aminoacido.

Info

Publication number
ES2187203T3
ES2187203T3 ES99951564T ES99951564T ES2187203T3 ES 2187203 T3 ES2187203 T3 ES 2187203T3 ES 99951564 T ES99951564 T ES 99951564T ES 99951564 T ES99951564 T ES 99951564T ES 2187203 T3 ES2187203 T3 ES 2187203T3
Authority
ES
Spain
Prior art keywords
soap
amino acid
pharmaceutical compositions
grease
administrable pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99951564T
Other languages
English (en)
Inventor
Ernesto J Castillo
Steven Howard Gerson
Wesley Wehsin Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Application granted granted Critical
Publication of ES2187203T3 publication Critical patent/ES2187203T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una composición farmacéutica administrable tópicamente conservada, que comprende un sistema conservante en la que el sistema conservante consiste esencialmente en i) al menos un jabón de ácido graso/aminoácido que tiene un componente de ácido graso derivado de un ácido graso C8- C24, y un componente aminoácido seleccionado del grupo que consiste en lisina y arginina; ii) uno o más ácidos antifúngicos farmacéuticamente aceptables seleccionados del grupo que consiste en ácido bórico; ácido benzoico; ácido salicílico; ácido sórbico; ácido láctico; ácido acético; y sus sales farmacéuticamente aceptables; y iii) uno o más agentes quelantes farmacéuticamente aceptables seleccionados del grupo que consiste en ácido diaminoetilentetracético; ácido etilenglicol-bis-(b-aminoetiléter) N,N,N¿,N¿¿tetraacético; ácido 1,2-bis(2- aminofenoxi)etano-N,N,N¿,N¿-tetraacético; etilen-N,N¿- diglicocola; ácido 2,2¿-(etilendiimino)-dibutírico; y sus sales farmacéuticamente aceptables.
ES99951564T 1998-10-27 1999-09-21 Sistema conservante para composiciones farmaceuticas administrables topicamente que contiene un jabon de acido graso/aminoacido. Expired - Lifetime ES2187203T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10581998P 1998-10-27 1998-10-27

Publications (1)

Publication Number Publication Date
ES2187203T3 true ES2187203T3 (es) 2003-05-16

Family

ID=22307952

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99951564T Expired - Lifetime ES2187203T3 (es) 1998-10-27 1999-09-21 Sistema conservante para composiciones farmaceuticas administrables topicamente que contiene un jabon de acido graso/aminoacido.

Country Status (13)

Country Link
US (1) US6284749B1 (es)
EP (1) EP1124535B1 (es)
JP (1) JP2002528404A (es)
AT (1) ATE229324T1 (es)
AU (1) AU753462B2 (es)
BR (1) BR9914799A (es)
CA (1) CA2340225A1 (es)
DE (1) DE69904498T2 (es)
DK (1) DK1124535T3 (es)
ES (1) ES2187203T3 (es)
PT (1) PT1124535E (es)
TW (1) TW581688B (es)
WO (1) WO2000024375A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444710B1 (en) 1998-10-27 2002-09-03 Alcon Manufacturing, Ltd. Use of certain fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
EP1214094A1 (en) * 1999-09-21 2002-06-19 Alcon Laboratories, Inc. Use of fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topical pharmaceutical compositions
US6716970B2 (en) 2000-04-21 2004-04-06 Adjuvant Pharmaceuticals, Llc Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof
BR0111415B1 (pt) * 2001-04-28 2012-12-11 composição antimicrobiana compreendendo sorbato de potássio e lae.
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US6806213B2 (en) * 2001-12-20 2004-10-19 Kimberly-Clark Worldwide, Inc. Disposable wash cloth and method of using
CA2470520A1 (en) * 2001-12-21 2003-07-24 3M Innovative Properties Company Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient
JP2005514440A (ja) * 2001-12-21 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー アミドおよび／またはエステルを含有する、賦形剤化合物を含む、医用エアロゾル組成物
JP2005514437A (ja) * 2001-12-21 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー イオン対複合体を含む医薬用エアロゾル製剤
JP4725699B2 (ja) * 2002-04-08 2011-07-13 ライオン株式会社 眼科用組成物及び眼科用組成物配合用防腐剤
JP2010031052A (ja) * 2002-04-08 2010-02-12 Lion Corp 眼科用組成物、及び眼科製剤用防腐組成物
WO2003086332A1 (en) * 2002-04-11 2003-10-23 Dvm Pharmaceuticals, Inc. Antimicrobial wash and carrier solutions, and uses thereof
US20040266776A1 (en) 2003-06-25 2004-12-30 Gil Daniel W. Methods of preventing and reducing the severity of stress-associated conditions
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formulations of palonosetron
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
MY143789A (en) * 2003-02-18 2011-07-15 Helsinn Healthcare Sa Use of palonosetron treating post- operative nausea and vomiting
US7125967B2 (en) * 2003-10-08 2006-10-24 Adjuvant Pharmaceuticals, Llc Water-soluble chitosan having low endotoxin concentration and methods for making and using the same
US20060167072A1 (en) * 2004-01-30 2006-07-27 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
ITCR20040004A1 (it) * 2004-02-05 2004-05-05 I C F Ind Chimica Fine S R L Detergente auricolare per animali, in particolare per cani e gatti
US8796206B2 (en) * 2007-11-15 2014-08-05 Amgen Inc. Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration
US20090298956A1 (en) * 2008-05-28 2009-12-03 Chowhan Masood A Self-preserved emulsions
DE102009034771B4 (de) 2009-07-25 2011-09-01 Martin Schmitt Hautschutzmittel
AU2010282099B2 (en) * 2009-08-12 2012-12-06 Lunan Better Pharmaceutical Co., Ltd. Pharmaceutical solution of cetirizine hydrochloride
CN106398905A (zh) * 2016-09-06 2017-02-15 佛山市芊茹化妆品有限公司 2‑氨基‑2‑甲基丙烷的羟基取代物在氨基酸透明皂中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275503A (en) 1964-08-26 1966-09-27 Patterson Co C Method for the protection of loci susceptible to the growth of undesired microorganisms
US4380637A (en) 1978-11-30 1983-04-19 Johnson & Johnson/Mona Industries, Inc. Imidazoline phosphobetaines
US4485029A (en) 1984-03-19 1984-11-27 Minnesota Mining And Manufacturing Company Disinfecting method and compositions
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
GB2172298B (en) 1985-03-01 1988-11-23 Procter & Gamble Mild detergent mousse
CA1302280C (en) 1986-04-21 1992-06-02 Jon Joseph Kabara Topical antimicrobial pharmaceutical compositions and methods
US5000868A (en) 1987-04-03 1991-03-19 Wittpenn Jr John R Surfactant compositions
US5093126A (en) 1987-09-26 1992-03-03 Alcon Laboratories, Inc. Glaucoma formulations comprising an anionic, polysulfonic acid polymer having mucomimetic properties and a polystyrene sulfonic polymer
JPH0665058A (ja) * 1992-08-24 1994-03-08 Pola Chem Ind Inc 洗浄剤組成物
US5520920A (en) 1992-08-28 1996-05-28 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
US5504113A (en) 1994-03-02 1996-04-02 Allergan, Inc. Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug
US5536305A (en) 1994-06-08 1996-07-16 Yu; Bing Low leaching compositions for wood
AU2673395A (en) 1994-06-20 1996-01-15 Unilever Plc Improvements relating to antimicrobial cleaning compositions
US5494937A (en) 1994-07-22 1996-02-27 Alcon Laboratories, Inc. Saline solution for treating contact lenses
WO1996003158A1 (en) 1994-07-22 1996-02-08 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5641480A (en) 1994-12-08 1997-06-24 Lever Brothers Company, Division Of Conopco, Inc. Hair care compositions comprising heteroatom containing alkyl aldonamide compounds

Also Published As

Publication number Publication date
DE69904498T2 (de) 2003-04-24
BR9914799A (pt) 2001-07-10
EP1124535A1 (en) 2001-08-22
DK1124535T3 (da) 2003-01-06
AU6398199A (en) 2000-05-15
WO2000024375A1 (en) 2000-05-04
EP1124535B1 (en) 2002-12-11
DE69904498D1 (de) 2003-01-23
US6284749B1 (en) 2001-09-04
CA2340225A1 (en) 2000-05-04
ATE229324T1 (de) 2002-12-15
PT1124535E (pt) 2003-04-30
AU753462B2 (en) 2002-10-17
TW581688B (en) 2004-04-01
JP2002528404A (ja) 2002-09-03

Similar Documents

Publication Publication Date Title
ES2187203T3 (es) Sistema conservante para composiciones farmaceuticas administrables topicamente que contiene un jabon de acido graso/aminoacido.
PE20011304A1 (es) Composicion farmaceutica que comprende una sal acida de amina simpaticomimetica soluble en agua y un denaturante y metodo para interferir fisicamente con la extraccion de una sal acida de una amina simpaticomimetica soluble en agua a partir de la mis
BR9810634A (pt) Composições detergente lìquidas estruturadas,contendo ácido graxo, não-aquosas
BR9914813A (pt) Sistema conservante para composições farmacêuticas administráveis topicamente
ES2188607T3 (es) Composiciones enzimaticas liquidas estabilizadas.
ES2145933T3 (es) Formulacion para la conservacion de la madera que comprende un complejo de un cation cobre y una diamina alcoxilada.
ID28295A (id) Komposisi-komposisi permen
ES2170383T3 (es) Composiciones acidas espesadas.
AR017205A1 (es) ANILIDAS MIMÉTICAS DE ÁCIDO RETINOICO, PROCESOS PARA PREPARAR DICHOS COMPUESTOS, COMPOSICIONES FARMACÉUTICAS QUE LOS COMPRENDEN, UN PROCESO PARA PREPARAR DICHAS COMPOSICIONES Y EL USO DE DICHOS COMPUESTOS EN LA ELABORACIoN DE MEDICAMENTOS.
ES2153686T3 (es) Composiciones liquidas de limpieza para multiples usos en microemulsion.
ATE477351T1 (de) Korrosionsinhibitierende zusammensetzungen
ES2170918T3 (es) Inhibidor de proteina quinasa c sustituidos con halo.
ES2179103T3 (es) Composicion detergente.
MX9405434A (es) Composicion de peroxido de hidrogeno.
PE123899A1 (es) Formulacion que contiene un opioide en combinacion con un agonista alfa-adrenergico y su utilizacion como analgesico
DE69701530D1 (de) Zusammensetzungen in blockform mit niedrigen gehalt an fettsäure seifen
ES2193003A1 (es) Uso dermatologico y preparacion dermatologica.
ES2178362T3 (es) Sistema de actividad antimicrobiana y su utilizacion, particularmente en los campos cosmetico y dermatologico.
ES2184812T3 (es) Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa.
DK0813585T3 (da) Rengøringssammensætninger
ES2173173T3 (es) Composiciones detergentes que contienen percarbonato y amilasa.
EA199900962A1 (ru) Композиция солюбилизированного сертралина
PE11695A1 (es) Composicion detergente que comprende un agente para soltar la suciedad
BR9913971A (pt) Uso de um composto
ES2176475T3 (es) Composiciones de inhibidor bowman-birk para el tratamiento de enferm edades inflamatorias.