ES2187566T3 - Formulaciones farmaceuticas mejoradas que contienen ibuprofeno y codeina. - Google Patents

Formulaciones farmaceuticas mejoradas que contienen ibuprofeno y codeina.

Info

Publication number
ES2187566T3
ES2187566T3 ES95928574T ES95928574T ES2187566T3 ES 2187566 T3 ES2187566 T3 ES 2187566T3 ES 95928574 T ES95928574 T ES 95928574T ES 95928574 T ES95928574 T ES 95928574T ES 2187566 T3 ES2187566 T3 ES 2187566T3
Authority
ES
Spain
Prior art keywords
codeina
pharmaceutical formulations
formulations containing
improved pharmaceutical
containing ibuprofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95928574T
Other languages
English (en)
Inventor
Brian Sterling Health E Holmes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9417041A external-priority patent/GB9417041D0/en
Priority claimed from GB9419921A external-priority patent/GB9419921D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of ES2187566T3 publication Critical patent/ES2187566T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

FORMULACIONES DE IBUPROFENO Y CODEINA ( O UNA SAL ACEPTABLE FARMACEUTICAMENTE DE CUALQUIERA DE ELLOS) QUE INCLUYE UN VEHICULO QUE TIENE UN DESINTEGRANTE, UN DILUYENTE, Y UN LUBRICANTE SUSTANCIALMENTE LIBRE DE ACIDO ESTEARICO E IONES DE ESTEARATO Y QUE SE SELECCIONA A PARTIR DE ACEITES VEGETALES HIDROGENADOS. LAS FORMULACIONES PREFERIDAS SON TABLETAS COMPRIMIDAS DE FORMA DIRECTA Y SON UTILES PARA TRATAR EL DOLOR Y LA INFLAMACION.
ES95928574T 1994-08-23 1995-08-16 Formulaciones farmaceuticas mejoradas que contienen ibuprofeno y codeina. Expired - Lifetime ES2187566T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9417041A GB9417041D0 (en) 1994-08-23 1994-08-23 Improved formulations
GB9419921A GB9419921D0 (en) 1994-10-04 1994-10-04 Improved formulations

Publications (1)

Publication Number Publication Date
ES2187566T3 true ES2187566T3 (es) 2003-06-16

Family

ID=26305507

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95928574T Expired - Lifetime ES2187566T3 (es) 1994-08-23 1995-08-16 Formulaciones farmaceuticas mejoradas que contienen ibuprofeno y codeina.

Country Status (24)

Country Link
EP (1) EP0777477B1 (es)
JP (1) JP3874793B2 (es)
KR (1) KR100397082B1 (es)
CN (1) CN1083265C (es)
AT (1) ATE227574T1 (es)
AU (1) AU699224B2 (es)
BG (1) BG63329B1 (es)
BR (1) BR9508760A (es)
CA (1) CA2156768A1 (es)
CZ (1) CZ287558B6 (es)
DE (1) DE69528838T2 (es)
DK (1) DK0777477T3 (es)
ES (1) ES2187566T3 (es)
HU (1) HU227759B1 (es)
MX (1) MX9701390A (es)
NO (1) NO322200B1 (es)
NZ (1) NZ291223A (es)
PL (1) PL181215B1 (es)
PT (1) PT777477E (es)
RU (1) RU2140782C1 (es)
SK (1) SK282183B6 (es)
TW (1) TW493984B (es)
UA (1) UA42781C2 (es)
WO (1) WO1996005834A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009130342A1 (es) * 2008-04-23 2009-10-29 Farmasierra Manufacturing, S.L. Formulación farmacéutica mejorada a base de ibuprofeno y codeína

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608073B1 (en) 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
DE10003757A1 (de) * 2000-01-28 2001-08-02 Knoll Ag Ibuprofen-Wirkstoffzubereitung
JP2001253826A (ja) * 2000-03-09 2001-09-18 Maruzen Pharmaceut Co Ltd 内服用剤
US7183410B2 (en) 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
ES2646326T3 (es) 2005-08-03 2017-12-13 Sprout Pharmaceuticals, Inc. Uso de flibanserina en el tratamiento de la obesidad
CA2626134C (en) 2005-10-29 2013-12-24 Boehringer Ingelheim International Gmbh Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
ZA200803566B (en) * 2005-12-12 2009-10-28 Adcock Ingram Ltd Pharmaceutical compositions
JP2009541443A (ja) 2006-06-30 2009-11-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 尿失禁及び関連疾患の治療のためのフリバンセリン
WO2008007426A1 (en) * 2006-07-12 2008-01-17 Aska Pharmaceutical Co., Ltd. Analgesic agent
EP2054041A2 (en) 2006-08-14 2009-05-06 Boehringer Ingelheim International GmbH Formulations of flibanserin and method for manufacturing the same
IL197129A (en) 2006-08-25 2014-08-31 Boehringer Ingelheim Int Controlled release system and method for production
KR20090065513A (ko) * 2006-10-05 2009-06-22 코와 가부시키가이샤 이부프로펜 및 트라넥삼산을 함유하는 고형 제제
CL2008002693A1 (es) 2007-09-12 2009-10-16 Boehringer Ingelheim Int Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad
ES2365961B1 (es) * 2010-03-30 2013-01-24 Farmasierra Manufacturing S.L. Formulación farmacéutica a base de ibuprofeno y codeína de estabilidad mejorada.
KR101317809B1 (ko) 2011-06-07 2013-10-16 한미약품 주식회사 암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물
KR20140096571A (ko) 2013-01-28 2014-08-06 한미약품 주식회사 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
US20170252452A1 (en) 2014-08-28 2017-09-07 Sanofi-Aventis Deutschland Gmbh Film coated tablet for the treatment of acute pain
CN105395508B (zh) * 2015-12-14 2018-06-29 西南药业股份有限公司 一种洛芬待因复方制剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571400A (en) * 1984-12-18 1986-02-18 Belleview Pharmaceutical, Inc. Dihydrocodeine/ibuprofen pharmaceutical compositions and method
GB8905815D0 (en) * 1989-03-14 1989-04-26 Beecham Group Plc Medicament
GB9121204D0 (en) * 1991-10-04 1991-11-20 Euro Celtique Sa Medicament

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009130342A1 (es) * 2008-04-23 2009-10-29 Farmasierra Manufacturing, S.L. Formulación farmacéutica mejorada a base de ibuprofeno y codeína
US8491930B2 (en) 2008-04-23 2013-07-23 Farmasierra Manufacturing, S.L. Pharmaceutical formulation containing ibuprofen and codeine

Also Published As

Publication number Publication date
AU3228995A (en) 1996-03-14
EP0777477A1 (en) 1997-06-11
CA2156768A1 (en) 1996-02-24
KR100397082B1 (ko) 2004-02-11
KR970705389A (ko) 1997-10-09
TW493984B (en) 2002-07-11
EP0777477B1 (en) 2002-11-13
DK0777477T3 (da) 2003-03-17
WO1996005834A1 (en) 1996-02-29
CZ54697A3 (en) 1997-12-17
NO970782D0 (no) 1997-02-20
NZ291223A (en) 1998-12-23
HUT77385A (hu) 1998-04-28
SK23697A3 (en) 1997-08-06
PT777477E (pt) 2003-03-31
DE69528838T2 (de) 2003-07-10
PL181215B1 (pl) 2001-06-29
PL318807A1 (en) 1997-07-07
BG101252A (en) 1998-02-27
UA42781C2 (uk) 2001-11-15
CN1083265C (zh) 2002-04-24
NO322200B1 (no) 2006-08-28
BG63329B1 (bg) 2001-10-31
BR9508760A (pt) 1998-01-13
HU227759B1 (en) 2012-02-28
RU2140782C1 (ru) 1999-11-10
ATE227574T1 (de) 2002-11-15
DE69528838D1 (de) 2002-12-19
AU699224B2 (en) 1998-11-26
JP3874793B2 (ja) 2007-01-31
JPH10504557A (ja) 1998-05-06
MX9701390A (es) 1998-06-30
CZ287558B6 (en) 2000-12-13
SK282183B6 (sk) 2001-11-06
CN1159754A (zh) 1997-09-17
NO970782L (no) 1997-02-20

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