ES2188847T3 - Derivados 9-n-etenil de 9(s)-eritromicilamina. - Google Patents
Derivados 9-n-etenil de 9(s)-eritromicilamina.Info
- Publication number
- ES2188847T3 ES2188847T3 ES97118554T ES97118554T ES2188847T3 ES 2188847 T3 ES2188847 T3 ES 2188847T3 ES 97118554 T ES97118554 T ES 97118554T ES 97118554 T ES97118554 T ES 97118554T ES 2188847 T3 ES2188847 T3 ES 2188847T3
- Authority
- ES
- Spain
- Prior art keywords
- sup
- sub
- group
- derivatives
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 229940041033 macrolides Drugs 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA INVENCION TRATA DE DERIVADOS DE 9 - N - ETENILO DE LA 9(S) ERITROMICILAMINA, NUEVOS ANTIBIOTICOS SEMISINTETICOS DE LA CLASE DE LOS MACROLIDOS DE FORMULA GENERAL (I): EN LA CUAL R SUP,1}Y R SUP,2} SON LOS MISMOS O DIFERENTES, Y REPRESENTAN NITRILO, UN GRUPO CARBOXILO DE FORMULA COOR SUP,3}, EN LA CUAL R SUP,3} REPRESENTA UN GRUPO ALQUILO C SUB,1} C SUB,4}, O UN GRUPO CETO DE FORMULA COR SUP,4}, EN LA CUAL R SUP,4} REPRESENTA UN GRUPO ALQUILO C SUB,1} - C SUB,4}, DE SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES CON ACIDOS INORGANICOS U ORGANICOS, DE UN PROCEDIMIENTO PARA SU PREPARACION, DE UN PROCEDIMIENTO PARA LA PREPARACION DE LAS COMPOSICIONES FARMACEUTICAS, ASI COMO DEL USO DE LAS COMPOSICIONES FARMACEUTICAS OBTENIDAS EN EL TRATAMIENTO DE INFECCIONES BACTERIANAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR960497A HRP960497B1 (en) | 1996-10-28 | 1996-10-28 | 9-n-ethenyl derivatives of 9(s)-erythromycylamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2188847T3 true ES2188847T3 (es) | 2003-07-01 |
Family
ID=10946479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97118554T Expired - Lifetime ES2188847T3 (es) | 1996-10-28 | 1997-10-24 | Derivados 9-n-etenil de 9(s)-eritromicilamina. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5854219A (es) |
| EP (1) | EP0838470B1 (es) |
| JP (1) | JPH10182689A (es) |
| CN (1) | CN1059212C (es) |
| AT (1) | ATE229028T1 (es) |
| BG (1) | BG63164B1 (es) |
| CA (1) | CA2217417C (es) |
| CZ (1) | CZ293429B6 (es) |
| DE (1) | DE69717583T2 (es) |
| ES (1) | ES2188847T3 (es) |
| HR (1) | HRP960497B1 (es) |
| HU (1) | HUP9701744A1 (es) |
| PL (1) | PL185878B1 (es) |
| PT (1) | PT838470E (es) |
| RU (1) | RU2170739C2 (es) |
| SI (1) | SI9700267B (es) |
| SK (1) | SK283535B6 (es) |
| UA (1) | UA54390C2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010083944A (ko) * | 1998-11-03 | 2001-09-03 | 실버스타인 아써 에이. | 신규 마크롤라이드 항생물질 |
| KR100428703B1 (ko) * | 2000-02-02 | 2004-04-30 | 한국과학기술연구원 | 헬리코박터 파이로리의 성장 억제 효과를 지닌 신규 마크로라이드 화합물 |
| US20020132782A1 (en) * | 2001-01-18 | 2002-09-19 | Zhenkun Ma | 9-amino erythromycin derivatives with antibacterial activity |
| RU2189222C1 (ru) * | 2001-07-30 | 2002-09-20 | Пятигорская государственная фармацевтическая академия | Мазь нистатина на полимерной основе, обладающая противогрибковым действием |
| PL374646A1 (en) * | 2002-07-08 | 2005-10-31 | Pliva-Istrazivacki Institutt D.O.O. | Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use |
| US7582611B2 (en) * | 2005-05-24 | 2009-09-01 | Pfizer Inc. | Motilide compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759251A (fr) * | 1969-11-21 | 1971-05-21 | Lilly Co Eli | Derives n-arylidene de l'erythromycylamine |
| GB1345524A (en) * | 1970-09-30 | 1974-01-30 | Lilly Industries Ltd | N-heteroarylidene erythomycylamines |
| DE2515026C2 (de) * | 1975-04-07 | 1982-09-23 | Jordan, Alfred, 1000 Berlin | Kontaktanordnung zum Einfügen einer Schmelzsicherung in eine Leitungsverbindung |
| DE2515076A1 (de) * | 1975-04-07 | 1976-10-28 | Thomae Gmbh Dr K | Neue erythromycinderivate, deren salze und verfahren zu ihrer herstellung |
| PH19293A (en) * | 1982-11-15 | 1986-03-04 | Pfizer | Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof |
| JPS61132941A (ja) * | 1984-12-03 | 1986-06-20 | Ricoh Co Ltd | 複写装置 |
| ZA87591B (en) * | 1986-02-03 | 1988-09-28 | Lilly Co Eli | Novel derivatives of eryhromycylamine |
| PT87417B (pt) * | 1987-05-06 | 1992-08-31 | Adir | Processo para a preparacao de novos compostos macrolidos |
| US5075289A (en) * | 1988-06-07 | 1991-12-24 | Abbott Laboratories | 9-r-azacyclic erythromycin antibiotics |
| CA2064985A1 (en) * | 1991-04-05 | 1992-10-06 | Robert R. Wilkening | 8a-aza-8a-homoertyhromycin cyclic lactams |
-
1996
- 1996-10-28 HR HR960497A patent/HRP960497B1/xx not_active IP Right Cessation
-
1997
- 1997-10-17 SI SI9700267A patent/SI9700267B/sl not_active IP Right Cessation
- 1997-10-23 US US08/956,352 patent/US5854219A/en not_active Expired - Fee Related
- 1997-10-23 JP JP9291076A patent/JPH10182689A/ja active Pending
- 1997-10-24 DE DE69717583T patent/DE69717583T2/de not_active Expired - Fee Related
- 1997-10-24 ES ES97118554T patent/ES2188847T3/es not_active Expired - Lifetime
- 1997-10-24 SK SK1449-97A patent/SK283535B6/sk unknown
- 1997-10-24 PT PT97118554T patent/PT838470E/pt unknown
- 1997-10-24 CZ CZ19973389A patent/CZ293429B6/cs not_active IP Right Cessation
- 1997-10-24 AT AT97118554T patent/ATE229028T1/de not_active IP Right Cessation
- 1997-10-24 EP EP97118554A patent/EP0838470B1/en not_active Expired - Lifetime
- 1997-10-27 UA UA97105222A patent/UA54390C2/uk unknown
- 1997-10-27 RU RU97118089/04A patent/RU2170739C2/ru not_active IP Right Cessation
- 1997-10-27 CN CN97122870A patent/CN1059212C/zh not_active Expired - Fee Related
- 1997-10-27 BG BG101996A patent/BG63164B1/bg unknown
- 1997-10-27 HU HU9701744A patent/HUP9701744A1/hu unknown
- 1997-10-27 CA CA002217417A patent/CA2217417C/en not_active Expired - Fee Related
- 1997-10-28 PL PL97322862A patent/PL185878B1/pl not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SK283535B6 (sk) | 2003-09-11 |
| CN1182090A (zh) | 1998-05-20 |
| HUP9701744A1 (hu) | 1998-05-28 |
| DE69717583T2 (de) | 2003-09-25 |
| CZ293429B6 (cs) | 2004-04-14 |
| CZ338997A3 (cs) | 1998-06-17 |
| US5854219A (en) | 1998-12-29 |
| CN1059212C (zh) | 2000-12-06 |
| PL185878B1 (pl) | 2003-08-29 |
| BG63164B1 (bg) | 2001-05-31 |
| SK144997A3 (en) | 1998-08-05 |
| BG101996A (en) | 1998-11-30 |
| PT838470E (pt) | 2003-03-31 |
| ATE229028T1 (de) | 2002-12-15 |
| RU2170739C2 (ru) | 2001-07-20 |
| DE69717583D1 (de) | 2003-01-16 |
| HRP960497B1 (en) | 2003-08-31 |
| CA2217417C (en) | 2004-07-06 |
| UA54390C2 (uk) | 2003-03-17 |
| SI9700267B (sl) | 2002-02-28 |
| HU9701744D0 (en) | 1997-12-29 |
| EP0838470A1 (en) | 1998-04-29 |
| SI9700267A (sl) | 1998-04-30 |
| HRP960497A2 (en) | 1999-02-28 |
| CA2217417A1 (en) | 1998-04-28 |
| JPH10182689A (ja) | 1998-07-07 |
| PL322862A1 (en) | 1998-05-11 |
| EP0838470B1 (en) | 2002-12-04 |
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