ES2191710T3 - Procedimiento para producir l-lisina y acido l-glutamico por fermentacion. - Google Patents

Procedimiento para producir l-lisina y acido l-glutamico por fermentacion.

Info

Publication number
ES2191710T3
ES2191710T3 ES95927999T ES95927999T ES2191710T3 ES 2191710 T3 ES2191710 T3 ES 2191710T3 ES 95927999 T ES95927999 T ES 95927999T ES 95927999 T ES95927999 T ES 95927999T ES 2191710 T3 ES2191710 T3 ES 2191710T3
Authority
ES
Spain
Prior art keywords
glutamic acid
produce
biotine
lisine
cepa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95927999T
Other languages
English (en)
Inventor
Eiichiro Kimura
Yoko Asakura
Akinori Uehara
Sumio Inoue
Yoshio Kawahara
Yasuhiko Yoshihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of ES2191710T3 publication Critical patent/ES2191710T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/84—Brevibacterium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/843—Corynebacterium

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE OBTIENE UNA CEPA MUTANTE CAPAZ DE PRODUCIR ACIDO LGLUTAMICO, EN AUSENCIA DE ANTAGONISTAS DE BIOTINA Y EN UN MEDIO QUE CONTIENE UNA CANTIDAD EN EXCESO DE BIOTINA. DICHA CEPA SE OBTIENE CONFIRIENDO SENSIBILIDAD A LA TEMPERATURA CON RESPECTO A LOS ANTAGONISTAS DE BIOTINA, A UNA BACTERIA CORYNEFORME PRODUCTORA DE ACIDO GLUTAMICO. LA CITADA CEPA SE CULTIVA EN UN MEDIO LIQUIDO, PARA PRODUCIR Y ACUMULAR ACIDO L-GLUTAMICO EN EL MISMO. LA LISINA Y EL ACIDO GLUTAMICO SE OBTIENEN SIMULTANEAMENTE, CONFIRIENDO A UNA BACTERIA CORYNEFORME, PRODUCTORA DE ACIDO L-GLUTAMICO, SENSIBILIDAD A LA TEMPERATURA CON RESPECTO A LOS ANTAGONISTAS DE BIOTINA, Y CAPACIDAD DE PRODUCCION DE L-LISINA, A FIN DE OBTENER UNA CEPA CAPAZ DE PRODUCIR ACIDO L-GLUTAMICO Y LISINA, EN UN MEDIO QUE CONTIENE BIOTINA EN EXCESO, Y EN AUSENCIA DE ANTAGONISTAS DE BIOTINA. DICHA CEPA SE CULTIVA EN UN MEDIO LIQUIDO, PARA PRODUCIR Y ACUMULAR L-LISINA Y ACIDO L-GLUTAMICO.
ES95927999T 1994-08-19 1995-08-09 Procedimiento para producir l-lisina y acido l-glutamico por fermentacion. Expired - Lifetime ES2191710T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19546594 1994-08-19

Publications (1)

Publication Number Publication Date
ES2191710T3 true ES2191710T3 (es) 2003-09-16

Family

ID=16341537

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95927999T Expired - Lifetime ES2191710T3 (es) 1994-08-19 1995-08-09 Procedimiento para producir l-lisina y acido l-glutamico por fermentacion.

Country Status (9)

Country Link
US (1) US5846790A (es)
EP (2) EP0780477B1 (es)
JP (1) JP2926991B2 (es)
CN (1) CN1079836C (es)
BR (1) BR9508730A (es)
DE (2) DE69535643D1 (es)
ES (1) ES2191710T3 (es)
PE (1) PE27597A1 (es)
WO (1) WO1996006180A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997008294A1 (fr) * 1995-08-23 1997-03-06 Ajinomoto Co., Inc. Procede de production d'acide l-glutamique par fermentation
GB9620144D0 (en) * 1996-09-27 1996-11-13 Cerestar Holding Bv Process for the production of of glumatic acid and the use of protein hydrolysates in this process
JP3812019B2 (ja) * 1996-11-21 2006-08-23 味の素株式会社 連続発酵によるｌ−グルタミン酸の製造法
BR9810990A (pt) * 1997-07-09 2000-08-08 Ajinomoto Kk Dna-bactéria corineforme, e processos para produzir acido l-glutâmico, e, para produzir l-lisina e ácido l-glutâmico.
US20030077765A1 (en) * 1997-07-09 2003-04-24 Ajinomoto Co. Inc. Temperature-sensitive dtsR gene
WO1999045131A1 (fr) * 1998-03-06 1999-09-10 Ajinomoto Co., Inc. Gene de la proteine fixatrice de penicilline et procede de production d'acide l-glutamique
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU746542B2 (en) * 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
EP1010755B1 (en) 1998-12-18 2010-10-06 Ajinomoto Co., Inc. Method for producing L-Glutamic acid by fermentation
JP2003159092A (ja) * 1999-07-02 2003-06-03 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
US6830903B1 (en) 1999-07-23 2004-12-14 Archer-Daniels-Midland Company Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
CA2377693C (en) 1999-07-23 2016-11-08 Archer-Daniels-Midland Company Methods for producing l-amino acids
CA2380613C (en) * 1999-08-02 2014-03-25 Archer-Daniels-Midland Company Production of l-lysine by corynebacterium strain having mutation in ilvbn operon
US6984512B1 (en) * 1999-08-02 2006-01-10 Archer-Daniels-Midland Company Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production
AU775818B2 (en) * 1999-08-02 2004-08-19 Archer-Daniels-Midland Company Novel bacterial strains, methods of preparing the same and uses thereof in fermentation processes for L-Lysine production
JP4427878B2 (ja) * 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
US6927046B1 (en) 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
US6737262B1 (en) * 2000-07-11 2004-05-18 Robert I. Bolla Animal feed containing polypeptides
US20080096242A1 (en) * 2004-09-01 2008-04-24 Agrotechnology And Food Innovations B.V. Enhanced Substrate Conversion Efficiency Of Fermentation Processes
DE102005017508A1 (de) * 2005-04-15 2006-10-19 Basf Ag Verfahren zur Gewinnung einer basischen Aminosäure aus einer Fermentationsbrühe II
CN101248170B (zh) * 2005-08-26 2011-01-26 味之素株式会社 产生l-谷氨酸的细菌和用于产生l-谷氨酸的方法
JP2010088301A (ja) * 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
CN101688176B (zh) 2007-04-17 2013-11-06 味之素株式会社 具有羧基的酸性物质的生产方法
CN103088081B (zh) * 2013-02-06 2014-12-03 中粮生化能源（龙江）有限公司 一种补加生物素的生产谷氨酸的发酵方法
CN113444655B (zh) * 2020-03-26 2023-05-16 吉林中粮生化有限公司 谷氨酸棒状杆菌、高谷氨酸产量的温度敏感型菌株及其获得方法、应用以及谷氨酸发酵方法
CN113292758B (zh) * 2021-05-25 2022-06-21 南京工业大学 一种同时具有电和温度响应的形状记忆复合材料及其制备方法和在固定化细胞中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5224593B2 (es) * 1973-10-17 1977-07-01
JPS561889A (en) * 1979-06-20 1981-01-10 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS57102193A (en) * 1980-12-17 1982-06-25 Kyowa Hakko Kogyo Co Ltd Preparation of l-glutamic acid
JPS62201585A (ja) * 1985-11-26 1987-09-05 Asahi Chem Ind Co Ltd クエン酸合成酵素産生遺伝子を含むｄｎａ断片
FR2590592B1 (fr) * 1985-11-26 1989-12-22 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour une enzyme catalysant une reaction dans le cycle tca et adn recombinant le contenant.
JPS6244171A (ja) * 1986-08-07 1987-02-26 Kyowa Hakko Kogyo Co Ltd Ｌ−グルタミン酸生産性新規微生物
JP2578463B2 (ja) * 1988-02-03 1997-02-05 協和醗酵工業株式会社 発酵法によるｌ−リジンの製造法
JPH029384A (ja) * 1988-06-28 1990-01-12 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−グルタミン酸の製造方法
JP3245881B2 (ja) * 1990-02-15 2002-01-15 味の素株式会社 塩基性アミノ酸と酸性アミノ酸の同時発酵法
KR0130196B1 (ko) * 1990-02-15 1998-04-03 도바 다다스 염기성 아미노산과 산성 아미노산의 동시 발효법

Also Published As

Publication number Publication date
DE69535643D1 (de) 2007-12-27
CN1161059A (zh) 1997-10-01
EP0780477A4 (en) 1999-06-30
DE69530306T2 (de) 2003-12-11
EP0780477B1 (en) 2003-04-09
BR9508730A (pt) 1997-10-21
PE27597A1 (es) 1997-08-12
EP1293560B1 (en) 2007-11-14
WO1996006180A1 (fr) 1996-02-29
EP1293560A3 (en) 2004-12-01
JP2926991B2 (ja) 1999-07-28
CN1079836C (zh) 2002-02-27
EP0780477A1 (en) 1997-06-25
EP1293560A2 (en) 2003-03-19
US5846790A (en) 1998-12-08
DE69530306D1 (de) 2003-05-15

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