ES2193535T3 - Biosensor compuesto por una membrana de lipidos que contiene canales de iones bloqueados. - Google Patents

Biosensor compuesto por una membrana de lipidos que contiene canales de iones bloqueados.

Info

Publication number
ES2193535T3
ES2193535T3 ES98929560T ES98929560T ES2193535T3 ES 2193535 T3 ES2193535 T3 ES 2193535T3 ES 98929560 T ES98929560 T ES 98929560T ES 98929560 T ES98929560 T ES 98929560T ES 2193535 T3 ES2193535 T3 ES 2193535T3
Authority
ES
Spain
Prior art keywords
lipid membrane
ion channels
membrane containing
containing blocked
biosensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98929560T
Other languages
English (en)
Inventor
Ian Robert Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coventry University
Original Assignee
Coventry University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coventry University filed Critical Coventry University
Application granted granted Critical
Publication of ES2193535T3 publication Critical patent/ES2193535T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

La invención se refiere a un biosensor que tiene una membrana de lípido (7) que contiene canales de confinamiento de iones sensibles a la presencia o otra forma de manifestación de moléculas de analitos en una muestra aplicada, cuando funciona, en un primer lado de la membrana de lípido (7). La membrana de lípido (7) se coloca entre un par de electrodos (1, 2) y se aplica una primera capa de gel poroso (4) al primer lado de la membrana de lípido (7).
ES98929560T 1997-06-14 1998-06-15 Biosensor compuesto por una membrana de lipidos que contiene canales de iones bloqueados. Expired - Lifetime ES2193535T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9712386.3A GB9712386D0 (en) 1997-06-14 1997-06-14 Biosensor

Publications (1)

Publication Number Publication Date
ES2193535T3 true ES2193535T3 (es) 2003-11-01

Family

ID=10814150

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98929560T Expired - Lifetime ES2193535T3 (es) 1997-06-14 1998-06-15 Biosensor compuesto por una membrana de lipidos que contiene canales de iones bloqueados.

Country Status (15)

Country Link
US (1) US6177000B1 (es)
EP (1) EP0988533B1 (es)
JP (1) JP2002505007A (es)
KR (1) KR100550404B1 (es)
CN (1) CN1161606C (es)
AT (1) ATE233897T1 (es)
AU (1) AU726398B2 (es)
CA (1) CA2293284A1 (es)
DE (1) DE69811886T2 (es)
DK (1) DK0988533T3 (es)
ES (1) ES2193535T3 (es)
GB (1) GB9712386D0 (es)
NZ (1) NZ501640A (es)
PT (1) PT988533E (es)
WO (1) WO1998058248A1 (es)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US20020144905A1 (en) 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
US7244349B2 (en) * 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US6758961B1 (en) 1997-12-17 2004-07-06 Ecole Polytechnique Federale De Lausanne Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
GB9812783D0 (en) 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
US7204922B1 (en) * 1999-07-26 2007-04-17 Johan-Valentin Kahl Method and device for the electrophoretic separation of particles, especially of macromolecules, by electrophoresis
JP2003511694A (ja) * 1999-10-12 2003-03-25 ゲラルト・ヴィーガント 高時間分解能のインピーダンス分光
AU1047401A (en) * 1999-11-08 2001-06-06 Cytion Sa Apparatus and methods for positioning and analyzing biological membranous objects
KR100446468B1 (ko) * 2001-05-18 2004-09-01 주식회사 아이센스 시료도입의 능력을 향상시킨 크로마토그래피 기능의다공성 박막이 구비된 바이오센서
US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7270730B2 (en) 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE10057832C1 (de) * 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
US20060029955A1 (en) 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
AU2002307218A1 (en) * 2001-03-24 2002-10-08 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US20050196746A1 (en) * 2001-03-24 2005-09-08 Jia Xu High-density ion transport measurement biochip devices and methods
US20050009004A1 (en) * 2002-05-04 2005-01-13 Jia Xu Apparatus including ion transport detecting structures and methods of use
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
WO2002100460A2 (en) * 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US20070100255A1 (en) * 2002-04-19 2007-05-03 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
CA2448902C (en) * 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7537571B2 (en) 2001-06-12 2009-05-26 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
AU2002348683A1 (en) * 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) * 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
US8360992B2 (en) * 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7244265B2 (en) * 2002-04-19 2007-07-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) * 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) * 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
AU2003231749A1 (en) 2002-04-19 2003-11-03 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7892183B2 (en) * 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7291117B2 (en) * 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) * 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) * 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US20070142748A1 (en) * 2002-04-19 2007-06-21 Ajay Deshmukh Tissue penetration device
US8784335B2 (en) * 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7717863B2 (en) * 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) * 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7524293B2 (en) * 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) * 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
AU2003231300A1 (en) * 2002-05-04 2003-11-17 Aviva Biosciences Corporation Apparatus including ion transport detecting structures and methods of use
AU2003245272A1 (en) * 2002-05-10 2003-11-11 The Texas A And M University System Stochastic sensing through covalent interactions
US20040067481A1 (en) * 2002-06-12 2004-04-08 Leslie Leonard Thermal sensor for fluid detection
EP1578286A4 (en) * 2002-12-13 2009-01-14 Pelikan Technologies Inc METHOD AND DEVICE FOR MEASURING ANALYTES
US7265881B2 (en) * 2002-12-20 2007-09-04 Hewlett-Packard Development Company, L.P. Method and apparatus for measuring assembly and alignment errors in sensor assemblies
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
EP2238892A3 (en) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Apparatus for body fluid sampling
ES2490740T3 (es) * 2003-06-06 2014-09-04 Sanofi-Aventis Deutschland Gmbh Aparato para toma de muestras de fluido sanguíneo y detección de analitos
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7604592B2 (en) 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
EP1671096A4 (en) 2003-09-29 2009-09-16 Pelikan Technologies Inc METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc METHOD AND DEVICE FOR A VARIABLE USER INTERFACE
US7822454B1 (en) * 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US8828203B2 (en) * 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND DEVICE FOR A LIQUID DETECTION DEVICE
US7638092B2 (en) 2004-09-17 2009-12-29 Japan Science And Technology Agency Artificial lipid bilayer membrane lipid substitution method, artificial lipid bilayer membrane obtained by using lipid substitution method, artificial lipid bilayer membrane formation device and ion permeation measuring device
US20080214917A1 (en) * 2004-12-30 2008-09-04 Dirk Boecker Method and apparatus for analyte measurement test time
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US20060184065A1 (en) * 2005-02-10 2006-08-17 Ajay Deshmukh Method and apparatus for storing an analyte sampling and measurement device
GB0505971D0 (en) * 2005-03-23 2005-04-27 Isis Innovation Delivery of molecules to a lipid bilayer
US20070191736A1 (en) * 2005-10-04 2007-08-16 Don Alden Method for loading penetrating members in a collection device
US20070276290A1 (en) * 2005-10-04 2007-11-29 Dirk Boecker Tissue Penetrating Apparatus
US20100196203A1 (en) * 2007-02-20 2010-08-05 Gurdial Singh Sanghera Formation of Lipid Bilayers
GB2447043A (en) * 2007-02-20 2008-09-03 Oxford Nanolabs Ltd Lipid bilayer sensor system
GB0724736D0 (en) * 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
US20100187132A1 (en) * 2008-12-29 2010-07-29 Don Alden Determination of the real electrochemical surface areas of screen printed electrodes
US9375169B2 (en) * 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
JP4958941B2 (ja) * 2009-05-08 2012-06-20 株式会社日立製作所 分析用素子
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
AU2013249126B2 (en) 2012-04-19 2015-10-01 Aytu Bioscience, Inc. Multiple layer gel
US9360446B2 (en) 2012-10-23 2016-06-07 Aytu Bioscience, Inc. Methods and systems for measuring and using the oxidation-reduction potential of a biological sample
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
KR101490584B1 (ko) 2013-03-08 2015-02-05 (주) 더바이오 액체/젤 계면을 이용한 전류법 기반의 퍼클로레이트 이온 검출용 칩 센서와 이를 포함하는 검출장치
GB201418512D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Electrical device with detachable components
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
GB2568895B (en) 2017-11-29 2021-10-27 Oxford Nanopore Tech Ltd Microfluidic device
GB2574048B (en) 2018-05-24 2021-06-16 Oxford Nanopore Tech Ltd Nanopore sensor component with electrostatic discharge protection
JP7492200B2 (ja) 2019-03-12 2024-05-29 オックスフォード ナノポール テクノロジーズ ピーエルシー ナノ細孔センシングデバイスと操作方法およびその成形方法
EP4675256A3 (en) 2020-07-17 2026-01-28 Oxford Nanopore Technologies PLC Nanopore sensing device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766960A (en) 1987-07-27 1998-06-16 Australian Membrane And Biotechnology Research Institute Receptor membranes
CA1335879C (en) 1987-07-27 1995-06-13 Bruce Andrew Cornell Receptor membranes
US5111221A (en) 1988-05-13 1992-05-05 United States Of America As Represented By The Secretary Of The Navy Receptor-based sensor
EP0639269B1 (en) 1991-03-27 2002-06-12 Ambri Limited Ionic reservoir at electrode surface
JPH07508342A (ja) 1992-04-22 1995-09-14 エコール ポリテクニーク フェデラル ドゥ ローザンヌ（エーペーエフエル） 脂質膜センサー
WO1995008637A1 (en) 1993-09-21 1995-03-30 Washington State University Research Foundation Immunoassay comprising ligand-conjugated, ion channel receptor immobilized in lipid film

Also Published As

Publication number Publication date
EP0988533A1 (en) 2000-03-29
WO1998058248A1 (en) 1998-12-23
CA2293284A1 (en) 1998-12-23
EP0988533B1 (en) 2003-03-05
PT988533E (pt) 2003-06-30
AU7926698A (en) 1999-01-04
CN1161606C (zh) 2004-08-11
NZ501640A (en) 2001-11-30
KR100550404B1 (ko) 2006-02-09
US6177000B1 (en) 2001-01-23
CN1301343A (zh) 2001-06-27
DK0988533T3 (da) 2003-07-07
KR20010013583A (ko) 2001-02-26
ATE233897T1 (de) 2003-03-15
JP2002505007A (ja) 2002-02-12
DE69811886D1 (de) 2003-04-10
DE69811886T2 (de) 2004-03-04
HK1027623A1 (en) 2001-01-19
GB9712386D0 (en) 1997-08-13
AU726398B2 (en) 2000-11-09

Similar Documents

Publication Publication Date Title
DK0988533T3 (da) Biosensor omfattende en lipidmembran indeholdende styrede io kanaler
BR9812016A (pt) Sensor eletroquìmico de baixo volume
ATE412049T1 (de) Multiarraysystem zur integration von bioarrays
AU3270797A (en) Multilayer enzyme electrode membranes and methods of making same
TWI256975B (en) Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
ATE386815T1 (de) Methoden und syteme zur überwachung intrazellulärer bindereaktionen
KR880004796A (ko) 이온전기도입용 석고 구조 조립품
ES2157669T3 (es) Un dispositivo para realizar un ensayo, uso de una membrana en la fabricacion de dicho dispositivo, kit que comprende dicho dispositivo, y metodo para la deteccion de un analito usando dicho dispositivo.
ES2316597T8 (es) Instrumentos analíticos, biosensores y métodos
KR960040313A (ko) 샘플 호울더용 밀폐제
DE60132311D1 (de) Funktionalisierte eingekapselte fluoreszierende nanokristalle
ES2154250T3 (es) Tira de ensayo de biosensor electroquimico.
ES2141073T1 (es) Nuevos reactivos y metodo de lisis de eritrocitos.
NZ335886A (en) Biosensor incorporating a surfactant
ATE80736T1 (de) Transparentes teststreifensystem.
AU1390995A (en) Solid state sensors
AU9066998A (en) Use of check surfaces for identifying disturbing samples in a detection procedure
CA2130947A1 (en) Dry Elements, Test Devices, Test Kits and Methods for Chemiluminescent Detection of Analytes Using Peroxidase-Labeled Reagents
ATE234467T1 (de) Immunoassay von vollblutproben
DE60138610D1 (de) Teststreifen mit poröser Filterschicht
FI953093A7 (fi) Menetelmiä, joilla voidaan havaita ja hoitaa yksilöitä, joilla on epän ormaaleja soluja, jotka ekspressoivat HLA-A2/tyrosinaasi-peptidiantige enejä
DK158167C (da) Elektrokemisk maaleelektrodeindretning, membran til en elektrokemisk maaleelektrodeindretning og et membranmonteringssaet til montering af en membran paa en elektrokemisk maaleelektrodeindretning
DK0889951T3 (da) Sensor og modificeret menbran til denne sensor
NL1002238A1 (nl) Verschildrukindicateur.
ES8606651A1 (es) Un metodo para detectar una secuencia de polinucleotidos en un analito