ES2194457T3 - Complejo de platino, su preparacion y aplicacion terapeutica. - Google Patents

Complejo de platino, su preparacion y aplicacion terapeutica.

Info

Publication number
ES2194457T3
ES2194457T3 ES99920540T ES99920540T ES2194457T3 ES 2194457 T3 ES2194457 T3 ES 2194457T3 ES 99920540 T ES99920540 T ES 99920540T ES 99920540 T ES99920540 T ES 99920540T ES 2194457 T3 ES2194457 T3 ES 2194457T3
Authority
ES
Spain
Prior art keywords
platinum complex
preparation
therapeutic application
carbon atoms
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99920540T
Other languages
English (en)
Inventor
Frantisek Zak
Adolf Mistr
Anna Poulova
Milan Melka
Jaroslav Turanek
Dana Zaluska
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Lachema AS
Original Assignee
Pliva Lachema AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema AS filed Critical Pliva Lachema AS
Application granted granted Critical
Publication of ES2194457T3 publication Critical patent/ES2194457T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un complejo de platino con número de oxidación II de fórmula (I) en la que X representa un átomo de halógeno, A representa un grupo -NH2-R, en el que R es un resto hidrocarbonado tricíclico que contiene 10 a 14 átomos de carbono, que puede estar opcionalmente sustituido en el anillo tricíclico con uno o dos grupo(s) alquilo de 1 a 4 átomos de carbono.
ES99920540T 1998-05-27 1999-05-24 Complejo de platino, su preparacion y aplicacion terapeutica. Expired - Lifetime ES2194457T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ19981627A CZ288406B6 (en) 1998-05-27 1998-05-27 Platinum complex of oxidation number II, process for preparing such complex, the complex functioning as medicament and pharmaceutical composition in which the complex is comprised

Publications (1)

Publication Number Publication Date
ES2194457T3 true ES2194457T3 (es) 2003-11-16

Family

ID=5463561

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99920540T Expired - Lifetime ES2194457T3 (es) 1998-05-27 1999-05-24 Complejo de platino, su preparacion y aplicacion terapeutica.

Country Status (21)

Country Link
US (1) US6350737B1 (es)
EP (1) EP1082329B1 (es)
JP (1) JP3647748B2 (es)
CN (1) CN1124278C (es)
AU (1) AU741381B2 (es)
BG (1) BG64598B1 (es)
BR (1) BR9910668A (es)
CA (1) CA2331464C (es)
CZ (1) CZ288406B6 (es)
DE (1) DE69905714T2 (es)
ES (1) ES2194457T3 (es)
HR (1) HRP20000792B1 (es)
HU (1) HU228940B1 (es)
IL (1) IL139528A (es)
NO (1) NO328940B1 (es)
PL (1) PL191131B1 (es)
RS (1) RS49739B (es)
RU (1) RU2203901C2 (es)
SK (1) SK284398B6 (es)
UA (1) UA56314C2 (es)
WO (1) WO1999061450A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102312A1 (en) * 2004-04-27 2005-11-03 Mayne Pharma Limited Concentrated oxaliplatin solutions
EP2027853A3 (en) 2004-06-18 2011-01-05 Agennix USA Inc. Kinase inhibitors for treating cancers
US20080272022A1 (en) * 2004-07-14 2008-11-06 Gpc Biotech Ag Variable-Dose Packaging System
CZ2004964A3 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
US20120238488A1 (en) 2009-09-08 2012-09-20 Konstantinos Alevizopoulos Compounds and methods for treating neoplasia
KR101964169B1 (ko) * 2014-04-04 2019-04-01 다이호야쿠힌고교 가부시키가이샤 항종양성 백금 착체를 함유하는 항종양제 및 항종양 효과 증강제
CN104922688A (zh) * 2015-02-10 2015-09-23 昆明贵研药业有限公司 奥沙利铂的环糊精复合物及制备方法
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2060615B (en) * 1979-08-23 1983-06-22 Johnson Matthey Co Ltd Platinum-amine complexes
KR900003457B1 (ko) * 1986-12-18 1990-05-19 시오노기세이야꾸 가부시끼가이샤 암민-지환식아민-백금 착화합물 및 항종양제
US5225207A (en) * 1989-03-17 1993-07-06 Laboratoire Roger Bellon Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds

Also Published As

Publication number Publication date
BG104971A (en) 2001-08-31
NO328940B1 (no) 2010-06-21
CZ288406B6 (en) 2001-06-13
SK17742000A3 (sk) 2001-05-10
BR9910668A (pt) 2001-01-30
WO1999061450A1 (en) 1999-12-02
HRP20000792A2 (en) 2001-02-28
DE69905714T2 (de) 2003-11-13
IL139528A (en) 2004-06-20
CA2331464C (en) 2005-10-18
IL139528A0 (en) 2001-11-25
CN1124278C (zh) 2003-10-15
JP3647748B2 (ja) 2005-05-18
CZ162798A3 (cs) 1999-12-15
US6350737B1 (en) 2002-02-26
NO20005919L (no) 2000-11-23
HUP0201762A3 (en) 2004-03-01
PL191131B1 (pl) 2006-03-31
BG64598B1 (bg) 2005-08-31
SK284398B6 (sk) 2005-03-04
HRP20000792B1 (en) 2006-07-31
YU72000A (sh) 2002-10-18
RU2203901C2 (ru) 2003-05-10
EP1082329B1 (en) 2003-03-05
EP1082329A1 (en) 2001-03-14
HU228940B1 (en) 2013-07-29
PL344345A1 (en) 2001-11-05
CA2331464A1 (en) 1999-12-02
UA56314C2 (uk) 2003-05-15
JP2002516331A (ja) 2002-06-04
NO20005919D0 (no) 2000-11-23
AU741381B2 (en) 2001-11-29
HUP0201762A2 (en) 2002-09-28
AU3809299A (en) 1999-12-13
DE69905714D1 (de) 2003-04-10
RS49739B (sr) 2008-04-04
CN1303387A (zh) 2001-07-11

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