ES2196158T3 - Canal ionico. - Google Patents

Canal ionico.

Info

Publication number
ES2196158T3
ES2196158T3 ES96920970T ES96920970T ES2196158T3 ES 2196158 T3 ES2196158 T3 ES 2196158T3 ES 96920970 T ES96920970 T ES 96920970T ES 96920970 T ES96920970 T ES 96920970T ES 2196158 T3 ES2196158 T3 ES 2196158T3
Authority
ES
Spain
Prior art keywords
sodium channel
novel
ion channel
tetrodotoxin
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96920970T
Other languages
English (en)
Inventor
John Nicholas Wood
Armen Norakovitch Akopian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ionix Pharmaceuticals Ltd
Original Assignee
Ionix Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10776812&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2196158(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ionix Pharmaceuticals Ltd filed Critical Ionix Pharmaceuticals Ltd
Application granted granted Critical
Publication of ES2196158T3 publication Critical patent/ES2196158T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Thin Film Transistor (AREA)
  • Optical Communication System (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN NUEVO CANAL DE SODIO DE APERTURA POR VOLTAJE INSENSIBLE A TETRODOTOXINA LOCALIZADO ESPECIFICAMENTE EN NEURONAS SENSORIALES DE MAMIFERO. SE PROPORCIONAN ASIMISMO SECUENCIAS DE ACIDOS NUCLEICOS QUE CODIFICAN EL NUEVO CANAL DE SODIO, VECTORES, CELULAS HUESPED Y METODOS PARA IDENTIFICAR MODULADORES DEL NUEVO CANAL DE SODIO PARA SU USO EN EL TRATAMIENTO DEL DOLOR.
ES96920970T 1995-06-28 1996-06-25 Canal ionico. Expired - Lifetime ES2196158T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9513180.1A GB9513180D0 (en) 1995-06-28 1995-06-28 Ion channel

Publications (1)

Publication Number Publication Date
ES2196158T3 true ES2196158T3 (es) 2003-12-16

Family

ID=10776812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96920970T Expired - Lifetime ES2196158T3 (es) 1995-06-28 1996-06-25 Canal ionico.

Country Status (12)

Country Link
US (3) US6451554B1 (es)
EP (2) EP1281717A3 (es)
JP (1) JPH11509090A (es)
AT (1) ATE235512T1 (es)
AU (1) AU721798B2 (es)
CA (1) CA2221294A1 (es)
DE (1) DE69626984T2 (es)
DK (1) DK0835261T3 (es)
ES (1) ES2196158T3 (es)
GB (1) GB9513180D0 (es)
PT (1) PT835261E (es)
WO (1) WO1997001577A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel
US6184349B1 (en) 1995-10-11 2001-02-06 Syntex (Usa) Inc. Cloned peripheral nerve, tetrodotoxin-resistant sodium channel α-subunit
US6030810A (en) 1997-02-26 2000-02-29 Delgado; Stephen Gregory Cloned tetrodotoxin-sensitive sodium channel α-subunit and a splice variant thereof
EP0884386A1 (en) * 1997-05-30 1998-12-16 Synthelabo Sodium channel receptor
ATE347596T1 (de) * 1997-10-29 2006-12-15 Univ Mcgill Dna kodierend für einen humanen protonenabhängigen ionenkanal und deren verwendungen
CH693031A5 (de) * 1997-11-20 2003-01-31 Hoffmann La Roche Nucleinsäure, die einen Nervengewebe-Natriumkanal kodiert.
WO1999027097A2 (en) * 1997-11-20 1999-06-03 Medical College Of Georgia Research Institute, Inc. CLONING OF A TETRODOTOXIN-RESISTANT SODIUM CHANNEL α-SUBUNIT
EP1053250A4 (en) * 1998-01-29 2003-04-09 Univ Yale MODULATION OF SODIUM CHANNELS IN DORSAL SPINAL GANGLIA
US6573067B1 (en) 1998-01-29 2003-06-03 Yale University Nucleic acid encoding sodium channels in dorsal root ganglia
GB9805793D0 (en) * 1998-03-18 1998-05-13 Glaxo Group Ltd Sodium ion channels
US20030228666A1 (en) * 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
DE1252330T1 (de) 1999-11-26 2003-11-27 Mcgill University, Montreal Loci der idiopathischen epilepsie, mutationen derselben und verfahren zu deren verwendung zur feststellung, prognose und behandlung von epilepsie
GB0006024D0 (en) * 2000-03-14 2000-05-03 Glaxo Group Ltd Altered ion channel proteins
AU2001273888A1 (en) * 2000-07-05 2002-01-14 Neurosearch A/S New sodium channel (rnav1.5a) and use thereof
JP4701374B2 (ja) * 2000-08-04 2011-06-15 大学共同利用機関法人自然科学研究機構 ＮａＶ２チャネル遺伝子欠損非ヒト動物
CN1269482C (zh) * 2001-05-18 2006-08-16 威克斯医药有限公司 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用
GB0120238D0 (en) 2001-08-20 2001-10-10 Univ College Of London Sodium channel regulators and modulators
CA2474751A1 (en) 2002-02-25 2003-09-04 Vanderbilt University Expression system for human brain-specific voltage-gated sodium channel, type 1
GB0211833D0 (en) * 2002-05-22 2002-07-03 Univ London Sodium channel regulators and modulators
WO2004087956A2 (en) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Cell lines for the functional expression of nav1.8
US20080020376A1 (en) * 2004-03-10 2008-01-24 Akopian Armen N Enriched Cdna Expression Libraries and Methods of Making and Using Same
AR051829A1 (es) 2004-10-27 2007-02-14 Schering Corp Composiciones y metodos para inhibicion de nav 1 mediante arn corto de interferencia
US7932058B2 (en) * 2007-06-08 2011-04-26 Senomyx, Inc. Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays
CN105445476B (zh) * 2015-12-17 2018-03-23 中山大学中山眼科中心 一种基于组织支架的三维视杯来源神经样细胞的钠离子通道检测方法
WO2023283618A1 (en) * 2021-07-08 2023-01-12 Children's Medical Center Corporation Systems and methods for delivery based on supramolecular nanostructures

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380836A (en) 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
WO1990009391A1 (en) 1989-02-13 1990-08-23 Arch Development Corporation Nucleic acid encoding sodium channel protein
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel
US6184349B1 (en) 1995-10-11 2001-02-06 Syntex (Usa) Inc. Cloned peripheral nerve, tetrodotoxin-resistant sodium channel α-subunit

Also Published As

Publication number Publication date
AU721798B2 (en) 2000-07-13
US20030176648A1 (en) 2003-09-18
WO1997001577A1 (en) 1997-01-16
GB9513180D0 (en) 1995-08-30
EP0835261B1 (en) 2003-03-26
JPH11509090A (ja) 1999-08-17
DE69626984D1 (de) 2003-04-30
AU6234596A (en) 1997-01-30
CA2221294A1 (en) 1997-01-16
EP1281717A3 (en) 2003-04-23
US7112418B2 (en) 2006-09-26
PT835261E (pt) 2003-08-29
ATE235512T1 (de) 2003-04-15
US20050221394A1 (en) 2005-10-06
EP0835261A1 (en) 1998-04-15
DK0835261T3 (da) 2003-07-21
US6451554B1 (en) 2002-09-17
DE69626984T2 (de) 2003-12-18
EP1281717A2 (en) 2003-02-05

Similar Documents

Publication Publication Date Title
ES2196158T3 (es) Canal ionico.
NL300273I1 (nl) DNA dat humaan papillomavirus type 18 codeert.
CY1111950T1 (el) 32 ανθρωπινες εκκρινομενες πρωτεϊνες
ES2194852T3 (es) Inhibidor de metaloproteinasa de tejido de tipo tres (timp-3).
ATE270428T1 (de) Vorrichtung und verfahren zur elektrophorese
PT666914E (pt) Nova proteina ligando da selectina p
ATE391175T1 (de) Multidrug resistenz gen
FI852956A0 (fi) Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia
NZ239357A (en) Human mk gene and protein sequence
DE3683447D1 (de) Verfahren zur herstellung von humanlysozym.
EP1609856A3 (en) Brain or heart cyclic nucleotide gated ion channel compounds and uses thereof
PT920501E (pt) Neuritina um neurogene
FR2719216B1 (fr) Composition pour le traitement et la protection des cheveux à base de céramides et de polymères de Vinylpyrrolidone.
NO892029L (no) Fremgangsmaate ved spesifikk genetisk manipulering av mikroorganisme.
AU8811298A (en) Novel peptides and polypeptides useful for regenerating the nervous system
BR9610070A (pt) Sequência de ácido nucleico polipetídeos compostos antifibrótico e processo para tratar distúrbios ou doenças relacionadas com fibrose para usar a sequência de dna e para produzir c-proteinase recombinante
WO1995035373A3 (en) Nucleic acid molecules encoding human contactin
IL117316A0 (en) Acarbose genes process for the isolation thereof and their use
GB2329896A (en) Enzyme and DNA sequence encoding same
GB2333527A (en) Therapeutic gene