ES2196366T3 - Inhibidor de turbidez sub-epitelial. - Google Patents

Inhibidor de turbidez sub-epitelial.

Info

Publication number
ES2196366T3
ES2196366T3 ES97942193T ES97942193T ES2196366T3 ES 2196366 T3 ES2196366 T3 ES 2196366T3 ES 97942193 T ES97942193 T ES 97942193T ES 97942193 T ES97942193 T ES 97942193T ES 2196366 T3 ES2196366 T3 ES 2196366T3
Authority
ES
Spain
Prior art keywords
epitelial
sub
subepitelial
same
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97942193T
Other languages
English (en)
Inventor
Yoichi Iwaki
Ikuo Tobari
Susumu Okamoto
Tatsuro Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIHON TENGANYAKU CO Ltd
Kissei Pharmaceutical Co Ltd
Original Assignee
NIHON TENGANYAKU CO Ltd
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIHON TENGANYAKU CO Ltd, Kissei Pharmaceutical Co Ltd filed Critical NIHON TENGANYAKU CO Ltd
Application granted granted Critical
Publication of ES2196366T3 publication Critical patent/ES2196366T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION SE REFIERE A UN INHIBIDOR DE LA OPACIDAD SUBEPITELIAL DE LA CORNEA QUE COMPRENDE COMO INGREDIENTE ACTIVO ACIDO N-(3,4-DIMETOXICINAMOIL)ANTRANILICO REPRESENTADO POR LA FORMULA (I) O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO, EL INHIBIDOR ES UTIL PARA LA PREVENCION O EL TRATAMIENTO DE LA OPACIDAD SUBEPITELIAL CORNEAL PROVOCADA POR UNA HERIDA DURANTE UNA OPERACION DE CIRUGIA REFRACTIVA TAL COMO UNA QUERATECTOMIA O UNA QUERATOTOMIA RADIAL, ASI COMO POR UNA HERIDA EXTERNA.
ES97942193T 1996-09-28 1997-09-24 Inhibidor de turbidez sub-epitelial. Expired - Lifetime ES2196366T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29222296 1996-09-28

Publications (1)

Publication Number Publication Date
ES2196366T3 true ES2196366T3 (es) 2003-12-16

Family

ID=17779091

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97942193T Expired - Lifetime ES2196366T3 (es) 1996-09-28 1997-09-24 Inhibidor de turbidez sub-epitelial.

Country Status (10)

Country Link
US (1) US6180673B1 (es)
EP (1) EP0950409B1 (es)
KR (1) KR100509421B1 (es)
AT (1) ATE235900T1 (es)
AU (1) AU4397197A (es)
CA (1) CA2266363C (es)
DE (1) DE69720521T2 (es)
ES (1) ES2196366T3 (es)
IL (1) IL129088A0 (es)
WO (1) WO1998013038A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ500300A (en) * 1997-04-18 2001-01-26 Kissei Pharmaceutical Compositions containing N-(3,4-dimethoxycinnamoyl) anthranilic acid for the treatment of excessive proliferation of retinal pigment epithelial cells
JP2002363075A (ja) * 2001-06-05 2002-12-18 Kao Corp 高血圧症予防・治療剤
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
WO2006073126A1 (ja) * 2005-01-06 2006-07-13 Kissei Pharmaceutical Co., Ltd. 慢性移植片対宿主症におけるドライアイの予防および治療剤
KR101948156B1 (ko) * 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
WO2019060696A1 (en) * 2017-09-25 2019-03-28 Surface Pharmaceuticals, Inc. OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07116029B2 (ja) * 1989-04-04 1995-12-13 キッセイ薬品工業株式会社 トラニラスト水溶液製剤
JP2632732B2 (ja) * 1989-11-06 1997-07-23 株式会社興人 Ｎ―（３’，４’―ジメトキシシンナモイル）アントラニル酸の製造方法
JPH05163222A (ja) * 1991-12-18 1993-06-29 Kissei Pharmaceut Co Ltd コラーゲン過剰合成疾患治療剤
WO1995019764A1 (en) * 1994-01-21 1995-07-27 Jonathan Javitt Cis-hydroxyproline analogs for eye treatment
CZ258598A3 (cs) * 1996-02-15 1998-11-11 Kissei Pharmaceutical Co., Ltd. Inhibitor neovaskularizace

Also Published As

Publication number Publication date
DE69720521T2 (de) 2004-03-04
KR100509421B1 (ko) 2005-08-22
WO1998013038A1 (fr) 1998-04-02
EP0950409A4 (en) 2001-04-11
ATE235900T1 (de) 2003-04-15
IL129088A0 (en) 2000-02-17
CA2266363A1 (en) 1998-04-02
DE69720521D1 (de) 2003-05-08
EP0950409B1 (en) 2003-04-02
EP0950409A1 (en) 1999-10-20
CA2266363C (en) 2007-05-22
US6180673B1 (en) 2001-01-30
KR20000048671A (ko) 2000-07-25
AU4397197A (en) 1998-04-17

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