ES2197781A1 - Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno. - Google Patents

Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.

Info

Publication number
ES2197781A1
ES2197781A1 ES200102705A ES200102705A ES2197781A1 ES 2197781 A1 ES2197781 A1 ES 2197781A1 ES 200102705 A ES200102705 A ES 200102705A ES 200102705 A ES200102705 A ES 200102705A ES 2197781 A1 ES2197781 A1 ES 2197781A1
Authority
ES
Spain
Prior art keywords
ibuprofen
volume
weight
pharmaceutical compositions
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200102705A
Other languages
English (en)
Other versions
ES2197781B1 (es
Inventor
Redondo Ana Maria Jimenez
Abanades Laura Berges
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmalider SA
Original Assignee
Farmalider SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmalider SA filed Critical Farmalider SA
Priority to ES200102705A priority Critical patent/ES2197781B1/es
Priority to AT02793140T priority patent/ATE352287T1/de
Priority to PCT/ES2002/000572 priority patent/WO2003047550A1/es
Priority to EP02793140A priority patent/EP1452169B1/en
Priority to DE60217903T priority patent/DE60217903T2/de
Priority to AU2002358819A priority patent/AU2002358819A1/en
Publication of ES2197781A1 publication Critical patent/ES2197781A1/es
Application granted granted Critical
Publication of ES2197781B1 publication Critical patent/ES2197781B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composiciones farmacéuticas líquidas de base acuosa en forma de suspensión para la administración por vía oral de ibuprofeno como principio activo que comprende de 0,8% a 6% en peso por volumen de ibuprofeno; de 0,1% a 2% en peso por volumen de cloruro sódico; de 0,01% a 0,5% en peso por volumen de sacarina sódica; de 0,1% a 2% en peso por volumen de uno o más agentes reguladores del pH en una cantidad suficiente como para ajustar el pH entre 3,8 y 4,8; de 0,01% a 0,5% en peso por volumen de un conservante; junto con una cantidad adecuada de otros excipientes farmacéuticamente aceptables de características viscosizantes y enmascarantes del sabor, así como un procedimiento para su preparación.
ES200102705A 2001-12-04 2001-12-04 Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno. Expired - Lifetime ES2197781B1 (es)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES200102705A ES2197781B1 (es) 2001-12-04 2001-12-04 Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.
AT02793140T ATE352287T1 (de) 2001-12-04 2002-12-02 Flüssige pharmazeutische zusammensetzungen auf wasserbasis in suspensionsform zur oralen verabreichung von ibuprofen
PCT/ES2002/000572 WO2003047550A1 (es) 2001-12-04 2002-12-02 Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno
EP02793140A EP1452169B1 (en) 2001-12-04 2002-12-02 Aqueous base liquid pharmaceutical compositions in suspension form for the oral administration of ibuprofen
DE60217903T DE60217903T2 (de) 2001-12-04 2002-12-02 Flüssige pharmazeutische zusammensetzungen auf wasserbasis in suspensionsform zur oralen verabreichung von ibuprofen
AU2002358819A AU2002358819A1 (en) 2001-12-04 2002-12-02 Aqueous base liquid pharmaceutical compositions in suspension form for the oral administration of ibuprofen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200102705A ES2197781B1 (es) 2001-12-04 2001-12-04 Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.

Publications (2)

Publication Number Publication Date
ES2197781A1 true ES2197781A1 (es) 2004-01-01
ES2197781B1 ES2197781B1 (es) 2005-02-16

Family

ID=8499662

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200102705A Expired - Lifetime ES2197781B1 (es) 2001-12-04 2001-12-04 Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.

Country Status (6)

Country Link
EP (1) EP1452169B1 (es)
AT (1) ATE352287T1 (es)
AU (1) AU2002358819A1 (es)
DE (1) DE60217903T2 (es)
ES (1) ES2197781B1 (es)
WO (1) WO2003047550A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2303468B1 (es) * 2007-01-22 2009-06-08 Masterfarm, S.L "una composicion farmaceutica pulverulenta que comprende ibuprofeno".
DE202008006492U1 (de) 2007-02-23 2008-08-21 Basf Se Verwendung von wasserdispergierbaren Carotinoid-Nanopartikeln als Geschmacksmodulatoren, Geschmacksmodulatoren, enthaltend wasserdispergierbare Carotinoid-Nanopartikel
ATE494800T1 (de) 2007-02-23 2011-01-15 Brain Biotechnology Res & Information Network Ag Verfahren zur geschmacksmodulation von stofflichen zusammensetzungen, die mindestens einen high intensity sweetener (his) enthalten
ATE494799T1 (de) 2007-02-23 2011-01-15 Brain Biotechnology Res & Information Network Ag Verwendung von wasserdispergierbaren carotinoid- nanopartikeln als geschmacksmodulatoren, geschmacksmodulatoren, enthaltend wasserdispergierbare carotinoid-nanopartikel, und verfahren zur geschmacksmodulation
ES2358862T3 (es) * 2007-02-23 2011-05-16 B.R.A.I.N. Biotechnology Research And Information Network Ag Procedimiento para la modulación del sabor de composiciones de sustancias que contienen al menos un edulcorante de alta intensidad (his).
EP2134194B1 (de) 2008-03-05 2012-05-02 B.R.A.I.N. Biotechnology Research And Information Network AG Verfahren zur geschmacksmodulation von stofflichen zusammensetzungen, die mindestens einen high intensity sweetener (his) enthalten
WO2009109227A1 (de) 2008-03-05 2009-09-11 Basf Se Verfahren zur geschmacksmodulation von stofflichen zusammensetzungen, die mindestens einen high intensity sweetener (his) enthalten
JPWO2019167977A1 (ja) * 2018-02-28 2021-02-04 大日本住友製薬株式会社 水性懸濁型医薬製剤
CN114931552A (zh) * 2021-02-12 2022-08-23 浙江贝灵生物医药有限公司 一种口服碱性溶媒组合物及其制备方法与应用
US20230364172A1 (en) * 2022-05-14 2023-11-16 Syncotrance, LLC Modulation of solubility, palatability, absorption, and bioavailability of mitragyna speciosa-derived compounds for oral and buccal delivery
CN115671046B (zh) * 2022-10-10 2024-04-26 澳美制药(苏州)有限公司 布洛芬混悬滴剂及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048428T3 (es) * 1989-03-28 1994-03-16 American Home Prod Composiciones de ibuprofeno de administracion oral.
ES2064634T3 (es) * 1989-06-28 1995-02-01 Mcneil Ppc Inc Suspension farmaceutica acuosa para agentes activos farmaceuticos esencialmente insolubles en agua.
ES2039281T3 (es) * 1987-07-08 1995-04-01 American Home Prod Composiciones de ibuprofeno para uso en pediatria.
EP0684819A1 (fr) * 1993-12-20 1995-12-06 Guerry, Arlette Compositions pharmaceutiques liquides a base d'ibuprofene
US6231890B1 (en) * 1996-05-02 2001-05-15 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2039281T3 (es) * 1987-07-08 1995-04-01 American Home Prod Composiciones de ibuprofeno para uso en pediatria.
ES2048428T3 (es) * 1989-03-28 1994-03-16 American Home Prod Composiciones de ibuprofeno de administracion oral.
ES2064634T3 (es) * 1989-06-28 1995-02-01 Mcneil Ppc Inc Suspension farmaceutica acuosa para agentes activos farmaceuticos esencialmente insolubles en agua.
EP0684819A1 (fr) * 1993-12-20 1995-12-06 Guerry, Arlette Compositions pharmaceutiques liquides a base d'ibuprofene
US6231890B1 (en) * 1996-05-02 2001-05-15 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug

Also Published As

Publication number Publication date
ES2197781B1 (es) 2005-02-16
EP1452169A1 (en) 2004-09-01
EP1452169B1 (en) 2007-01-24
DE60217903D1 (de) 2007-03-15
AU2002358819A1 (en) 2003-06-17
DE60217903T2 (de) 2007-11-22
WO2003047550A1 (es) 2003-06-12
ATE352287T1 (de) 2007-02-15

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