ES221509A1 - PROCEDIMIENTO DE PREPARACIoN DE NUEVAS AMIDAS - Google Patents
PROCEDIMIENTO DE PREPARACIoN DE NUEVAS AMIDASInfo
- Publication number
- ES221509A1 ES221509A1 ES0221509A ES221509A ES221509A1 ES 221509 A1 ES221509 A1 ES 221509A1 ES 0221509 A ES0221509 A ES 0221509A ES 221509 A ES221509 A ES 221509A ES 221509 A1 ES221509 A1 ES 221509A1
- Authority
- ES
- Spain
- Prior art keywords
- groups
- group
- phthalimido
- aminophenoxy
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title 1
- -1 acetamido, benzamido, diacetamido, succinimido, phthalimido Chemical group 0.000 abstract 33
- 150000001875 compounds Chemical class 0.000 abstract 9
- 239000002253 acid Substances 0.000 abstract 8
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 5
- 150000007513 acids Chemical class 0.000 abstract 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N hexane Substances CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 4
- QKVHAKICMNABGB-UHFFFAOYSA-N 2-(5-bromopentyl)isoindole-1,3-dione Chemical compound C1=CC=C2C(=O)N(CCCCCBr)C(=O)C2=C1 QKVHAKICMNABGB-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 3
- 229920002472 Starch Polymers 0.000 abstract 3
- 235000021355 Stearic acid Nutrition 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 239000003085 diluting agent Substances 0.000 abstract 3
- 150000002430 hydrocarbons Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 3
- 235000019359 magnesium stearate Nutrition 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 3
- 125000005544 phthalimido group Chemical group 0.000 abstract 3
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- 239000008107 starch Substances 0.000 abstract 3
- 235000019698 starch Nutrition 0.000 abstract 3
- 239000008117 stearic acid Substances 0.000 abstract 3
- 125000001302 tertiary amino group Chemical group 0.000 abstract 3
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 2
- 239000004375 Dextrin Substances 0.000 abstract 2
- 229920001353 Dextrin Polymers 0.000 abstract 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 230000010933 acylation Effects 0.000 abstract 2
- 238000005917 acylation reaction Methods 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 235000019425 dextrin Nutrition 0.000 abstract 2
- 150000001470 diamides Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 150000003949 imides Chemical class 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- DKNZRNMESDYLFN-UHFFFAOYSA-N n-[5-(4-aminophenoxy)pentyl]benzamide Chemical compound C1=CC(N)=CC=C1OCCCCCNC(=O)C1=CC=CC=C1 DKNZRNMESDYLFN-UHFFFAOYSA-N 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 abstract 2
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical compound [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 abstract 2
- FYRHIOVKTDQVFC-UHFFFAOYSA-M potassium phthalimide Chemical compound [K+].C1=CC=C2C(=O)[N-]C(=O)C2=C1 FYRHIOVKTDQVFC-UHFFFAOYSA-M 0.000 abstract 2
- AZOQUFPCCRLIER-UHFFFAOYSA-M potassium;4-nitrophenolate Chemical compound [K+].[O-]C1=CC=C([N+]([O-])=O)C=C1 AZOQUFPCCRLIER-UHFFFAOYSA-M 0.000 abstract 2
- 150000003141 primary amines Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 201000004409 schistosomiasis Diseases 0.000 abstract 2
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 2
- XUIVKWAWICCWIQ-UHFFFAOYSA-M sodium;formaldehyde;hydrogen sulfite Chemical class [Na+].O=C.OS([O-])=O XUIVKWAWICCWIQ-UHFFFAOYSA-M 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- RZCNIOWAJWZKDD-UHFFFAOYSA-N (4-hydroxyphenyl)-trimethylazanium;iodide Chemical compound [I-].C[N+](C)(C)C1=CC=C(O)C=C1 RZCNIOWAJWZKDD-UHFFFAOYSA-N 0.000 abstract 1
- XYOLFZARONRTOA-UHFFFAOYSA-N 1-phenoxypentan-1-amine Chemical compound CCCCC(N)OC1=CC=CC=C1 XYOLFZARONRTOA-UHFFFAOYSA-N 0.000 abstract 1
- XHUZBWUNHJZIHE-UHFFFAOYSA-N 2-(5-phenoxypentyl)isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1CCCCCOC1=CC=CC=C1 XHUZBWUNHJZIHE-UHFFFAOYSA-N 0.000 abstract 1
- YIRXUXAPVBOKED-UHFFFAOYSA-N 2-[5-(4-nitrophenoxy)pentyl]isoindole-1,3-dione Chemical compound C1=CC([N+](=O)[O-])=CC=C1OCCCCCN1C(=O)C2=CC=CC=C2C1=O YIRXUXAPVBOKED-UHFFFAOYSA-N 0.000 abstract 1
- SVDDJQGVOFZBNX-UHFFFAOYSA-N 2-chloroethyl carbonochloridate Chemical compound ClCCOC(Cl)=O SVDDJQGVOFZBNX-UHFFFAOYSA-N 0.000 abstract 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 abstract 1
- BVTLIIQDQAUXOI-UHFFFAOYSA-N 4-(benzylideneamino)phenol Chemical compound C1=CC(O)=CC=C1N=CC1=CC=CC=C1 BVTLIIQDQAUXOI-UHFFFAOYSA-N 0.000 abstract 1
- HCXJFMDOHDNDCC-UHFFFAOYSA-N 5-$l^{1}-oxidanyl-3,4-dihydropyrrol-2-one Chemical group O=C1CCC(=O)[N]1 HCXJFMDOHDNDCC-UHFFFAOYSA-N 0.000 abstract 1
- CBDLLOONIRUKRB-UHFFFAOYSA-N 5-(1,3-dioxoisoindol-2-yl)pentyl methanesulfonate Chemical compound C1=CC=C2C(=O)N(CCCCCOS(=O)(=O)C)C(=O)C2=C1 CBDLLOONIRUKRB-UHFFFAOYSA-N 0.000 abstract 1
- HFCUGSPFGNDAPO-UHFFFAOYSA-N 6-hydroxyhex-3-enyl 4-methylbenzenesulfonate Chemical compound C1(=CC=C(C=C1)S(=O)(=O)OCCC=CCCO)C HFCUGSPFGNDAPO-UHFFFAOYSA-N 0.000 abstract 1
- 241001659321 ANME-2 cluster Species 0.000 abstract 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical class OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- NONIOTIFYMWCAY-UHFFFAOYSA-N C1(C=2C(C(N1CCC=CCCO)=O)=CC=CC2)=O.C2(C=1C(C(N2)=O)=CC=CC1)=O.[K] Chemical compound C1(C=2C(C(N1CCC=CCCO)=O)=CC=CC2)=O.C2(C=1C(C(N2)=O)=CC=CC1)=O.[K] NONIOTIFYMWCAY-UHFFFAOYSA-N 0.000 abstract 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical class CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- KWNMXZKHOQQXMN-UHFFFAOYSA-N N-[4-[6-(1,3-dioxoisoindol-2-yl)hex-3-enoxy]phenyl]acetamide Chemical compound C1(C=2C(C(N1CCC=CCCOC1=CC=C(C=C1)NC(C)=O)=O)=CC=CC2)=O KWNMXZKHOQQXMN-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 abstract 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000004141 Sodium laurylsulphate Substances 0.000 abstract 1
- QMJDEXCUIQJLGO-UHFFFAOYSA-N [4-(methylamino)phenyl] hydrogen sulfate Chemical compound CNC1=CC=C(OS(O)(=O)=O)C=C1 QMJDEXCUIQJLGO-UHFFFAOYSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- GIIGAFADHXYOPM-UHFFFAOYSA-N amphotalide Chemical compound C1=CC(N)=CC=C1OCCCCCN1C(=O)C2=CC=CC=C2C1=O GIIGAFADHXYOPM-UHFFFAOYSA-N 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 150000001805 chlorine compounds Chemical class 0.000 abstract 1
- 125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 abstract 1
- 150000001991 dicarboxylic acids Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- LPKYKQBWTIDVHN-UHFFFAOYSA-N n-(4-hydroxyphenyl)-n-methylformamide Chemical compound O=CN(C)C1=CC=C(O)C=C1 LPKYKQBWTIDVHN-UHFFFAOYSA-N 0.000 abstract 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 125000000018 nitroso group Chemical group N(=O)* 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- NAYYNDKKHOIIOD-UHFFFAOYSA-N phthalamide Chemical compound NC(=O)C1=CC=CC=C1C(N)=O NAYYNDKKHOIIOD-UHFFFAOYSA-N 0.000 abstract 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical class OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 235000011056 potassium acetate Nutrition 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000000197 pyrolysis Methods 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 239000001632 sodium acetate Substances 0.000 abstract 1
- 235000017281 sodium acetate Nutrition 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- 235000012222 talc Nutrition 0.000 abstract 1
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Substances CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento de preparación de para-amino-fenoxialkil- y aminofenoxialkenil-amidas y sus derivados que contengan la estructura **(ver fórmula)** en la que R1 y R2 son iguales o distintos y cada uno representa un átomo de hidrógeno o un grupo alkilo hidroxi-alkilo (incluso polihidroxialkilo) o alcoxialkilo inferior A representa una cadena de hidrocarburo no ramificada saturada o etilénicamente no-saturada que contenga no menos de cinco ni más de nueve átomos de carbono y R representa un grupo mono- o di-acilamido caracterizándose porque comprende la condensación de un compuesto de la fórmula **(ver fórmula)** Z2 Y (en las que X representa un grupo amino terciario o un átomo o grupo susceptible de sustituirse por o de convertirse en un grupo amino primario secundario terciario Y representa el grupo R o un átomo o grupo que pueda sustituirse por o convertirse en el grupo R y Z1 y Z2 son átomos o grupos susceptibles de reaccionar entre sí para producir el enlace -O-A'- en el que A' representa el grupo A o un enlace hidrocarburado correspondiente menos saturado) seguida si es necesario por la conversión de los grupos X e Y en los grupos NR1R2 y R respectivamente y tambien si es necesario por la reducción del grupo A' para formar el grupo A.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1265954A GB769706A (en) | 1954-04-30 | 1954-04-30 | Improvements in or relating to amines and to processes for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES221509A1 true ES221509A1 (es) | 1955-11-16 |
Family
ID=10008770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0221509A Expired ES221509A1 (es) | 1954-04-30 | 1955-04-30 | PROCEDIMIENTO DE PREPARACIoN DE NUEVAS AMIDAS |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES221509A1 (es) |
| GB (1) | GB769706A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3995042A (en) * | 1973-09-07 | 1976-11-30 | E. R. Squibb & Sons, Inc. | Pyridine containing compounds |
| DE3635312A1 (de) * | 1986-10-17 | 1988-04-21 | Bayer Ag | Aminoalkoxy-triphendioxazin-reaktivfarbstoffe |
| SK18097A3 (en) * | 1996-02-28 | 1997-10-08 | American Cyanamid Co | Substituted omega £phenoxy, phenylthio, phenylsulfinyl, phenylsulfonyl| £alkyl, alkenyl or alkinyl|amino carboxamides, sulfonamides and phosphonyl amides, pharmaceutical preparation containing them, process for producing them and their use |
-
1954
- 1954-04-30 GB GB1265954A patent/GB769706A/en not_active Expired
-
1955
- 1955-04-30 ES ES0221509A patent/ES221509A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB769706A (en) | 1957-03-13 |
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