ES2228648T3 - Protesis ortopedica. - Google Patents

Protesis ortopedica.

Info

Publication number: ES2228648T3
Authority: ES; Spain
Prior art keywords: bioabsorbable; layer; adhesive; prosthesis; surface opposite
Prior art date: 1999-12-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES00986404T

Other languages

English (en)

Spanish (es)

Inventor

Keith E. Greenawalt

Timothy J. Butler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Genzyme Corp

Original Assignee

Genzyme Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-17

Filing date

2000-12-14

Publication date

2005-04-16

2000-12-14 Application filed by Genzyme Corp filed Critical Genzyme Corp

2005-04-16 Application granted granted Critical

2005-04-16 Publication of ES2228648T3 publication Critical patent/ES2228648T3/es

2020-12-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

230000000399 orthopedic effect Effects 0.000 title claims description 12
229920002674 hyaluronan Polymers 0.000 claims abstract description 54
229960003160 hyaluronic acid Drugs 0.000 claims abstract description 54
229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 50
239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 49
235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 49
239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 49
239000000853 adhesive Substances 0.000 claims abstract description 38
230000001070 adhesive effect Effects 0.000 claims abstract description 38
238000000034 method Methods 0.000 claims abstract description 18
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 54
229920000954 Polyglycolide Polymers 0.000 claims description 19
239000004743 Polypropylene Substances 0.000 claims description 17
239000000463 material Substances 0.000 claims description 17
-1 polypropylene Polymers 0.000 claims description 17
229920001155 polypropylene Polymers 0.000 claims description 17
210000001835 viscera Anatomy 0.000 claims description 17
239000000203 mixture Substances 0.000 claims description 13
229920000747 poly(lactic acid) Polymers 0.000 claims description 12
239000004626 polylactic acid Substances 0.000 claims description 12
239000011148 porous material Substances 0.000 claims description 12
229920001577 copolymer Polymers 0.000 claims description 8
239000004633 polyglycolic acid Substances 0.000 claims description 8
229920001610 polycaprolactone Polymers 0.000 claims description 7
238000003825 pressing Methods 0.000 claims description 6
239000004632 polycaprolactone Substances 0.000 claims description 3
229920000139 polyethylene terephthalate Polymers 0.000 claims description 3
239000005020 polyethylene terephthalate Substances 0.000 claims description 3
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
239000005014 poly(hydroxyalkanoate) Substances 0.000 claims description 2
229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims description 2
239000000622 polydioxanone Substances 0.000 claims description 2
229920000728 polyester Polymers 0.000 claims description 2
229920000903 polyhydroxyalkanoate Polymers 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 abstract description 4
230000017423 tissue regeneration Effects 0.000 abstract 1
150000003672 ureas Chemical class 0.000 abstract 1
239000006260 foam Substances 0.000 description 26
229920000339 Marlex Polymers 0.000 description 8
229920006362 Teflon® Polymers 0.000 description 8
230000003902 lesion Effects 0.000 description 7
VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 6
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
206010019909 Hernia Diseases 0.000 description 5
239000002253 acid Substances 0.000 description 5
241001465754 Metazoa Species 0.000 description 4
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 4
238000007654 immersion Methods 0.000 description 4
238000003475 lamination Methods 0.000 description 4
239000002953 phosphate buffered saline Substances 0.000 description 4
229910001220 stainless steel Inorganic materials 0.000 description 4
239000010935 stainless steel Substances 0.000 description 4
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
241000700159 Rattus Species 0.000 description 3
239000002131 composite material Substances 0.000 description 3
229940079593 drug Drugs 0.000 description 3
239000003814 drug Substances 0.000 description 3
230000035876 healing Effects 0.000 description 3
229920000642 polymer Polymers 0.000 description 3
239000000243 solution Substances 0.000 description 3
239000007921 spray Substances 0.000 description 3
238000012360 testing method Methods 0.000 description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
241000283973 Oryctolagus cuniculus Species 0.000 description 2
238000009826 distribution Methods 0.000 description 2
238000002513 implantation Methods 0.000 description 2
238000010348 incorporation Methods 0.000 description 2
230000008595 infiltration Effects 0.000 description 2
238000001764 infiltration Methods 0.000 description 2
239000008259 solid foam Substances 0.000 description 2
125000006850 spacer group Chemical group 0.000 description 2
238000005507 spraying Methods 0.000 description 2
239000000725 suspension Substances 0.000 description 2
230000004584 weight gain Effects 0.000 description 2
235000019786 weight gain Nutrition 0.000 description 2
FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
QMGYPNKICQJHLN-UHFFFAOYSA-M Carboxymethylcellulose cellulose carboxymethyl ether Chemical compound [Na+].CC([O-])=O.OCC(O)C(O)C(O)C(O)C=O QMGYPNKICQJHLN-UHFFFAOYSA-M 0.000 description 1
229920001661 Chitosan Polymers 0.000 description 1
208000005156 Dehydration Diseases 0.000 description 1
206010021620 Incisional hernias Diseases 0.000 description 1
239000004793 Polystyrene Substances 0.000 description 1
241000220317 Rosa Species 0.000 description 1
229910000831 Steel Inorganic materials 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
229940072056 alginate Drugs 0.000 description 1
229920000615 alginic acid Polymers 0.000 description 1
235000010443 alginic acid Nutrition 0.000 description 1
238000010171 animal model Methods 0.000 description 1
239000002260 anti-inflammatory agent Substances 0.000 description 1
229940124599 anti-inflammatory drug Drugs 0.000 description 1
150000001718 carbodiimides Chemical class 0.000 description 1
238000004040 coloring Methods 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000013270 controlled release Methods 0.000 description 1
230000002596 correlated effect Effects 0.000 description 1
230000006378 damage Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
230000018044 dehydration Effects 0.000 description 1
238000006297 dehydration reaction Methods 0.000 description 1
230000032798 delamination Effects 0.000 description 1
238000002845 discoloration Methods 0.000 description 1
238000001035 drying Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000000835 fiber Substances 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
208000014674 injury Diseases 0.000 description 1
238000003780 insertion Methods 0.000 description 1
230000037431 insertion Effects 0.000 description 1
210000000936 intestine Anatomy 0.000 description 1
230000001788 irregular Effects 0.000 description 1
239000011159 matrix material Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
239000002184 metal Substances 0.000 description 1
238000000386 microscopy Methods 0.000 description 1
210000003205 muscle Anatomy 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
210000002747 omentum Anatomy 0.000 description 1
210000003200 peritoneal cavity Anatomy 0.000 description 1
229920000151 polyglycol Polymers 0.000 description 1
239000010695 polyglycol Substances 0.000 description 1
229920002223 polystyrene Polymers 0.000 description 1
230000002980 postoperative effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
210000001139 rectus abdominis Anatomy 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
238000005096 rolling process Methods 0.000 description 1
229940126586 small molecule drug Drugs 0.000 description 1
239000010959 steel Substances 0.000 description 1
230000003637 steroidlike Effects 0.000 description 1
239000000126 substance Substances 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
238000012549 training Methods 0.000 description 1
238000009827 uniform distribution Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Composite Materials (AREA)
Materials Engineering (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Dermatology (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Surgery (AREA)
Vascular Medicine (AREA)
Materials For Medical Uses (AREA)
Prostheses (AREA)
Compounds Of Unknown Constitution (AREA)

ES00986404T 1999-12-17 2000-12-14 Protesis ortopedica. Expired - Lifetime ES2228648T3 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46669799A	1999-12-17	1999-12-17
US466697		1999-12-17

Publications (1)

Publication Number	Publication Date
ES2228648T3 true ES2228648T3 (es)	2005-04-16

Family

ID=23852752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES00986404T Expired - Lifetime ES2228648T3 (es)	1999-12-17	2000-12-14	Protesis ortopedica.

Country Status (11)

Country	Link
US (1)	US20030100955A1 (de)
EP (1)	EP1237588B1 (de)
JP (1)	JP2003516816A (de)
AT (1)	ATE283715T1 (de)
AU (1)	AU2264801A (de)
CA (1)	CA2393354A1 (de)
DE (1)	DE60016455T2 (de)
ES (1)	ES2228648T3 (de)
IL (1)	IL149800A0 (de)
PT (1)	PT1237588E (de)
WO (1)	WO2001043789A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040267349A1 (en) *	2003-06-27	2004-12-30	Kobi Richter	Amorphous metal alloy medical devices
US8382821B2 (en)	1998-12-03	2013-02-26	Medinol Ltd.	Helical hybrid stent
US7404819B1 (en)	2000-09-14	2008-07-29	C.R. Bard, Inc.	Implantable prosthesis
DE10155842A1 (de)	2001-11-14	2003-05-28	Ethicon Gmbh	Flächiges Implantat
DE10222872B4 (de)	2002-05-23	2018-08-16	Johnson & Johnson Medical Gmbh	Medizinisches Implantat und Verfahren zum Herstellen eines medizinischen Implantats
FR2840801B1 (fr) *	2002-06-18	2005-06-03	Cie De Rech En Composants Impl	Implant prothetique composite
DE10318801A1 (de) *	2003-04-17	2004-11-04	Aesculap Ag & Co. Kg	Flächiges Implantat und seine Verwendung in der Chirurgie
FR2856305B1 (fr)	2003-06-19	2007-08-24	Inst Nat Sante Rech Med	Protheses avec revetements biologiquement actifs
DE10353930A1 (de) *	2003-07-18	2005-02-03	Feg Textiltechnik	Textiles Intraperitoneal-Mesh
US20050113849A1 (en) *	2003-11-26	2005-05-26	Nicholas Popadiuk	Prosthetic repair device
US20050182443A1 (en)	2004-02-18	2005-08-18	Closure Medical Corporation	Adhesive-containing wound closure device and method
CA2563347C (en)	2004-04-20	2014-01-14	Genzyme Corporation	Surgical mesh-like implant
US20060009099A1 (en)	2004-07-12	2006-01-12	Closure Medical Corporation	Adhesive-containing wound closure device and method
US9000040B2 (en)	2004-09-28	2015-04-07	Atrium Medical Corporation	Cross-linked fatty acid-based biomaterials
WO2006036984A2 (en)	2004-09-28	2006-04-06	Atrium Medical Corporation	Stand-alone film and methods for making the same
US9012506B2 (en)	2004-09-28	2015-04-21	Atrium Medical Corporation	Cross-linked fatty acid-based biomaterials
US9278161B2 (en) *	2005-09-28	2016-03-08	Atrium Medical Corporation	Tissue-separating fatty acid adhesion barrier
US9427423B2 (en)	2009-03-10	2016-08-30	Atrium Medical Corporation	Fatty-acid based particles
DE102006033218B4 (de) *	2006-07-13	2011-11-10	Biocer Entwicklungs Gmbh	Modifiziertes künstliches Gewebe, Verfahren zu dessen Herstellung und dessen Verwendung
US7614258B2 (en)	2006-10-19	2009-11-10	C.R. Bard, Inc.	Prosthetic repair fabric
ES2387583T3 (es) *	2007-10-19	2012-09-26	Stryker Trauma Gmbh	Sustituto de hueso sintético, procedimiento para preparar el mismo y procedimiento para rellenar una cavidad en un sustrato
US8206632B2 (en) *	2007-12-18	2012-06-26	Ethicon, Inc.	Methods of making composite prosthetic devices having improved bond strength
US20090163936A1 (en) *	2007-12-21	2009-06-25	Chunlin Yang	Coated Tissue Engineering Scaffold
US20100082113A1 (en) *	2008-04-29	2010-04-01	Peter Gingras	Tissue repair implant
US20110038910A1 (en)	2009-08-11	2011-02-17	Atrium Medical Corporation	Anti-infective antimicrobial-containing biomaterials
FR2949688B1 (fr) *	2009-09-04	2012-08-24	Sofradim Production	Tissu avec picots revetu d'une couche microporeuse bioresorbable
US8758798B2 (en) *	2010-03-24	2014-06-24	Covidien Lp	Therapeutic implant
US8821585B2 (en) *	2010-06-14	2014-09-02	Ethicon, Inc.	Composite anisotropic tissue reinforcing implants having alignment markers and methods of manufacturing same
US9211175B2 (en) *	2010-07-08	2015-12-15	Covidien Lp	Self-detachable medical devices
WO2012009707A2 (en)	2010-07-16	2012-01-19	Atrium Medical Corporation	Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US8579990B2 (en)	2011-03-30	2013-11-12	Ethicon, Inc.	Tissue repair devices of rapid therapeutic absorbency
TWI561535B (en)	2011-10-06	2016-12-11	Bvw Holding Ag	Copolymers of hydrophobic and hydrophilic segments that reduce protein adsorption
KR101461652B1 (ko) *	2011-12-16	2014-11-21	주식회사 삼양바이오팜	유착방지용 조성물, 이를 포함하는 유착방지기능을 갖는 수술용 메쉬 복합체 및 이의 제조 방법
RU2687275C2 (ru) *	2013-02-01	2019-05-13	Аллерган, Инк.	Слезозаменитель, содержащий гиалуронат натрия и карбоксиметилцеллюлозу
EP3062740A4 (de) *	2013-11-01	2017-08-02	Atrium Medical Corporation	Positionierungsmittel und verfahren zur verwendung davon
EP3132927B1 (de) *	2014-03-31	2020-05-06	Toray Industries, Inc.	Mehrschichtfolie, integrierte folie damit und herstellungsverfahren dafür
US10786980B2 (en)	2014-06-18	2020-09-29	Toray Industries, Inc.	Laminate and production method therefor
DE102015013989A1 (de) *	2015-10-30	2017-05-04	Johnson & Johnson Medical Gmbh	Chirurgisches Implantat
US20170368230A1 (en) *	2016-06-23	2017-12-28	Dermagenesis, Llc	Matrix construction
US10792024B2 (en)	2016-09-28	2020-10-06	Ethicon, Inc.	Scaffolds with channels for joining layers of tissue at discrete points
USD848624S1 (en)	2016-09-29	2019-05-14	Ethicon, Inc.	Release paper for wound treatment devices
US10687986B2 (en)	2016-09-29	2020-06-23	Ethicon, Inc.	Methods and devices for skin closure
US10470935B2 (en)	2017-03-23	2019-11-12	Ethicon, Inc.	Skin closure systems and devices of improved flexibility and stretchability for bendable joints
US20180271505A1 (en)	2017-03-23	2018-09-27	Ethicon, Inc.	Scaffolds for Joining Layers of Tissue at Discrete Points
US11504446B2 (en)	2017-04-25	2022-11-22	Ethicon, Inc.	Skin closure devices with self-forming exudate drainage channels
US10993708B2 (en)	2018-07-31	2021-05-04	Ethicon, Inc.	Skin closure devices with interrupted closure
US12478488B2 (en)	2020-02-19	2025-11-25	Medinol Ltd.	Helical stent with enhanced crimping

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017229A (en)	1990-06-25	1991-05-21	Genzyme Corporation	Water insoluble derivatives of hyaluronic acid
US5632979A (en) *	1988-05-31	1997-05-27	University Of Florida Research Foundation, Inc.	Method and composition for preventing surgical adhesions
US6294202B1 (en) *	1994-10-06	2001-09-25	Genzyme Corporation	Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US5989535A (en) *	1997-08-15	1999-11-23	Soma Technologies	Polymeric bioadhesive emulsions and suspensions and methods of treatment
WO2000016822A1 (en) *	1998-09-21	2000-03-30	The Brigham And Women's Hospital, Inc.	Compositions and methods for tissue repair

2000
- 2000-12-14 DE DE60016455T patent/DE60016455T2/de not_active Expired - Fee Related
- 2000-12-14 AT AT00986404T patent/ATE283715T1/de not_active IP Right Cessation
- 2000-12-14 EP EP00986404A patent/EP1237588B1/de not_active Expired - Lifetime
- 2000-12-14 ES ES00986404T patent/ES2228648T3/es not_active Expired - Lifetime
- 2000-12-14 CA CA002393354A patent/CA2393354A1/en not_active Abandoned
- 2000-12-14 JP JP2001544925A patent/JP2003516816A/ja not_active Withdrawn
- 2000-12-14 PT PT00986404T patent/PT1237588E/pt unknown
- 2000-12-14 IL IL14980000A patent/IL149800A0/xx unknown
- 2000-12-14 AU AU22648/01A patent/AU2264801A/en not_active Abandoned
- 2000-12-14 WO PCT/US2000/033971 patent/WO2001043789A1/en not_active Ceased
2003
- 2003-01-13 US US10/341,121 patent/US20030100955A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2003516816A (ja)	2003-05-20
EP1237588B1 (de)	2004-12-01
PT1237588E (pt)	2005-03-31
DE60016455T2 (de)	2005-12-15
AU2264801A (en)	2001-06-25
WO2001043789A1 (en)	2001-06-21
CA2393354A1 (en)	2001-06-21
US20030100955A1 (en)	2003-05-29
EP1237588A1 (de)	2002-09-11
IL149800A0 (en)	2002-11-10
DE60016455D1 (de)	2005-01-05
ATE283715T1 (de)	2004-12-15

Publication	Publication Date	Title
ES2228648T3 (es)	2005-04-16	Protesis ortopedica.
ES2402435T3 (es)	2013-05-03	Dispositivo de reparación de tejido con un miembro de soporte bioabsorbible
ES2626126T3 (es)	2017-07-24	Dispositivo de colágeno y procedimiento de preparación del mismo
EP1738780B1 (de)	2016-03-30	Bioimplantierbarer Collagenträger
ES2549062T3 (es)	2015-10-22	Implante para ensanchar la válvula nasal, bioabsorbible y con múltiples capas
ES2289403T3 (es)	2008-02-01	Protesis implantable.
KR100895135B1 (ko)	2009-05-04	생분해성 및 난분해성 영역을 갖는 수술용 보철물
US20080071300A1 (en)	2008-03-20	Prosthetic repair device
US20110307077A1 (en)	2011-12-15	Composite anisotropic tissue reinforcing implants having alignment markers and methods of manufacturing same
JP2011200653A (ja)	2011-10-13	治療用移植片
JP2011200652A (ja)	2011-10-13	治療用移植片
CN117563042A (zh)	2024-02-20	包括编织物和非多孔膜的合成修复体以及用于形成该修复体的方法
ES2438491T3 (es)	2014-01-17	Dispositivo implantable que comprende un sustrato pre-recubierto con fibrina estabilizada
Nathanson et al.	1978	Histologic response to porous PMMA implant materials
SU904693A1 (ru)	1982-02-15	Протез сосуда
US20060095139A1 (en)	2006-05-04	Composite prosthetic implant
JP2016517298A (ja)	2016-06-16	単一面組織修復パッチ
CN108348317A (zh)	2018-07-31	外科植入物
ES2578907T3 (es)	2016-08-02	Dispositivo bioimplantable de colageno
AU2013202206B2 (en)	2015-06-11	Composite anisotropic tissue reinforcing implants having alignment markers and methods of manufacturing same