ES2243442T3 - Procedimiento de preparacion de derivados esteroides. - Google Patents

Procedimiento de preparacion de derivados esteroides.

Info

Publication number
ES2243442T3
ES2243442T3 ES01904504T ES01904504T ES2243442T3 ES 2243442 T3 ES2243442 T3 ES 2243442T3 ES 01904504 T ES01904504 T ES 01904504T ES 01904504 T ES01904504 T ES 01904504T ES 2243442 T3 ES2243442 T3 ES 2243442T3
Authority
ES
Spain
Prior art keywords
group
mixture
reaction
represented
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01904504T
Other languages
English (en)
Spanish (es)
Inventor
Shingo Yano
Ryutaro Yamagami
Kenji Nozaki
Tetsuji Asao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2243442T3 publication Critical patent/ES2243442T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES01904504T 2000-02-18 2001-02-16 Procedimiento de preparacion de derivados esteroides. Expired - Lifetime ES2243442T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000040927 2000-02-18
JP2000040927 2000-02-18

Publications (1)

Publication Number Publication Date
ES2243442T3 true ES2243442T3 (es) 2005-12-01

Family

ID=18564238

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01904504T Expired - Lifetime ES2243442T3 (es) 2000-02-18 2001-02-16 Procedimiento de preparacion de derivados esteroides.

Country Status (8)

Country Link
US (1) US6717002B2 (de)
EP (1) EP1172371B1 (de)
JP (1) JP4070463B2 (de)
AT (1) ATE297406T1 (de)
DE (1) DE60111304T2 (de)
ES (1) ES2243442T3 (de)
PT (1) PT1172371E (de)
WO (1) WO2001060836A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004515A1 (en) * 2001-07-06 2003-01-16 Chugai Seiyaku Kabushiki Kaisha Process for production of estradiol derivatives, intermediates used in the process and process for production thereof
WO2004046168A2 (en) * 2002-11-15 2004-06-03 The Henry M. Jackson Foundation Recombinant hiv-1 subclass d envelope glycoproteins
US9907707B2 (en) * 2011-06-03 2018-03-06 The Procter & Gamble Company Sensor systems comprising auxiliary articles
EP3572417B1 (de) 2011-10-14 2025-12-17 Sage Therapeutics, LLC 3,3-disubstituierte 19-nor-pregnan verbindungen, zusammensetzungen damit und verwendungen davon
KR102396328B1 (ko) 2013-04-17 2022-05-10 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
EP2986624B1 (de) 2013-04-17 2020-03-25 Sage Therapeutics, Inc. Neuroaktive 19-nor-steroide zur verwendung zur behandlung von krankheiten
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
SI3021852T1 (sl) 2013-07-19 2021-07-30 Sage Therapeutics, Inc. Nevroaktivni steroidi, sestavki in uporabe le-teh
AU2014308621C1 (en) 2013-08-23 2022-01-06 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN117024501A (zh) 2014-10-16 2023-11-10 萨奇治疗股份有限公司 靶向cns障碍的组合物和方法
ME03809B (de) 2014-10-16 2021-04-20 Sage Therapeutics Inc Zusammensetzungen und verfahren zur behandlung von störungen des zentralen nervensystems
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
EP4155314A1 (de) 2015-02-20 2023-03-29 Sage Therapeutics, Inc. Neuroaktive steroide, zusammensetzungen und verwendungen davon
MA45599A (fr) 2016-07-11 2019-05-15 Sage Therapeutics Inc Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation
WO2018013615A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
SG11202112391UA (en) 2019-05-31 2021-12-30 Sage Therapeutics Inc Neuroactive steroids and compositions thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058919A2 (en) * 2000-02-11 2001-08-16 Sri International Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one

Also Published As

Publication number Publication date
US6717002B2 (en) 2004-04-06
PT1172371E (pt) 2005-10-31
JP4070463B2 (ja) 2008-04-02
US20020143199A1 (en) 2002-10-03
WO2001060836A1 (en) 2001-08-23
EP1172371B1 (de) 2005-06-08
ATE297406T1 (de) 2005-06-15
DE60111304D1 (de) 2005-07-14
EP1172371A4 (de) 2003-04-02
EP1172371A1 (de) 2002-01-16
DE60111304T2 (de) 2005-11-10

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