ES2243442T3 - Procedimiento de preparacion de derivados esteroides. - Google Patents

Procedimiento de preparacion de derivados esteroides.

Info

Publication number
ES2243442T3
ES2243442T3 ES01904504T ES01904504T ES2243442T3 ES 2243442 T3 ES2243442 T3 ES 2243442T3 ES 01904504 T ES01904504 T ES 01904504T ES 01904504 T ES01904504 T ES 01904504T ES 2243442 T3 ES2243442 T3 ES 2243442T3
Authority
ES
Spain
Prior art keywords
group
mixture
reaction
represented
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01904504T
Other languages
English (en)
Spanish (es)
Inventor
Shingo Yano
Ryutaro Yamagami
Kenji Nozaki
Tetsuji Asao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2243442T3 publication Critical patent/ES2243442T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES01904504T 2000-02-18 2001-02-16 Procedimiento de preparacion de derivados esteroides. Expired - Lifetime ES2243442T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000040927 2000-02-18
JP2000040927 2000-02-18

Publications (1)

Publication Number Publication Date
ES2243442T3 true ES2243442T3 (es) 2005-12-01

Family

ID=18564238

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01904504T Expired - Lifetime ES2243442T3 (es) 2000-02-18 2001-02-16 Procedimiento de preparacion de derivados esteroides.

Country Status (8)

Country Link
US (1) US6717002B2 (de)
EP (1) EP1172371B1 (de)
JP (1) JP4070463B2 (de)
AT (1) ATE297406T1 (de)
DE (1) DE60111304T2 (de)
ES (1) ES2243442T3 (de)
PT (1) PT1172371E (de)
WO (1) WO2001060836A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004515A1 (en) * 2001-07-06 2003-01-16 Chugai Seiyaku Kabushiki Kaisha Process for production of estradiol derivatives, intermediates used in the process and process for production thereof
WO2004046168A2 (en) * 2002-11-15 2004-06-03 The Henry M. Jackson Foundation Recombinant hiv-1 subclass d envelope glycoproteins
US10271998B2 (en) * 2011-06-03 2019-04-30 The Procter & Gamble Company Sensor systems comprising anti-choking features
ES2738526T3 (es) 2011-10-14 2020-01-23 Sage Therapeutics Inc Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos
HRP20190232T1 (hr) 2013-04-17 2019-03-22 Sage Therapeutics, Inc. 19-nor c3,3-disupstituirani c21-n-pirazolil steroidi i postupci za njihovu upotrebu
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
HRP20200995T1 (hr) 2013-04-17 2020-11-27 Sage Therapeutics, Inc. 19-nor neuroaktivni steroidi za metode liječenja
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
SMT202100229T1 (it) 2013-07-19 2021-05-07 Sage Therapeutics Inc Steroidi neuroattivi, composizioni e loro usi
SMT202100048T1 (it) 2013-08-23 2021-03-15 Sage Therapeutics Inc Steroidi neuroattivi, composizioni e loro usi
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
AU2015331749A1 (en) 2014-10-16 2017-05-04 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
JP6742308B2 (ja) 2014-10-16 2020-08-19 セージ セラピューティクス， インコーポレイテッド Ｃｎｓ障害を処置するための組成物および方法
ES2793237T3 (es) 2014-11-27 2020-11-13 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos del SNC
SI3250210T1 (sl) * 2015-01-26 2021-07-30 Sage Therapeutics, Inc. Sestavki in metode za zdravljenje CNS motenj
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN109689673B (zh) 2016-07-11 2023-03-14 萨奇治疗股份有限公司 C17、c20和c21取代的神经活性类固醇及其使用方法
AU2017296295B2 (en) 2016-07-11 2022-02-24 Sage Therapeutics, Inc. C7, C12, and C16 substituted neuroactive steroids and their methods of use
CN114206900A (zh) 2019-05-31 2022-03-18 萨奇治疗股份有限公司 神经活性类固醇及其组合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6784170B2 (en) * 2000-02-11 2004-08-31 Sri International Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one

Also Published As

Publication number Publication date
DE60111304D1 (de) 2005-07-14
JP4070463B2 (ja) 2008-04-02
PT1172371E (pt) 2005-10-31
DE60111304T2 (de) 2005-11-10
US6717002B2 (en) 2004-04-06
ATE297406T1 (de) 2005-06-15
US20020143199A1 (en) 2002-10-03
EP1172371A1 (de) 2002-01-16
EP1172371A4 (de) 2003-04-02
EP1172371B1 (de) 2005-06-08
WO2001060836A1 (en) 2001-08-23

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