ES2249797T3 - Composiciones de lipidos solidos de componentes lipofilicos para mejorar la biodisponibilidad oral. - Google Patents

Composiciones de lipidos solidos de componentes lipofilicos para mejorar la biodisponibilidad oral.

Info

Publication number
ES2249797T3
ES2249797T3 ES97920049T ES97920049T ES2249797T3 ES 2249797 T3 ES2249797 T3 ES 2249797T3 ES 97920049 T ES97920049 T ES 97920049T ES 97920049 T ES97920049 T ES 97920049T ES 2249797 T3 ES2249797 T3 ES 2249797T3
Authority
ES
Spain
Prior art keywords
composition
dry
lipid
solid
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97920049T
Other languages
English (en)
Spanish (es)
Inventor
Shimon Amselem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmos Corp
Original Assignee
Pharmos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmos Corp filed Critical Pharmos Corp
Application granted granted Critical
Publication of ES2249797T3 publication Critical patent/ES2249797T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
ES97920049T 1996-04-02 1997-04-02 Composiciones de lipidos solidos de componentes lipofilicos para mejorar la biodisponibilidad oral. Expired - Lifetime ES2249797T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11777396 1996-04-02
IL11777396A IL117773A (en) 1996-04-02 1996-04-02 Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability

Publications (1)

Publication Number Publication Date
ES2249797T3 true ES2249797T3 (es) 2006-04-01

Family

ID=11068733

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97920049T Expired - Lifetime ES2249797T3 (es) 1996-04-02 1997-04-02 Composiciones de lipidos solidos de componentes lipofilicos para mejorar la biodisponibilidad oral.

Country Status (10)

Country Link
US (1) US5989583A (2)
EP (1) EP0954284B1 (2)
JP (1) JP4219403B2 (2)
AT (1) ATE301454T1 (2)
AU (1) AU722217B2 (2)
BR (1) BR9708423A (2)
DE (1) DE69733966T2 (2)
ES (1) ES2249797T3 (2)
IL (1) IL117773A (2)
WO (1) WO1997036577A1 (2)

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AU722217B2 (en) 2000-07-27
DE69733966T2 (de) 2006-05-18
BR9708423A (pt) 2000-01-04
EP0954284B1 (en) 2005-08-10
AU2433997A (en) 1997-10-22
IL117773A (en) 2000-10-31
US5989583A (en) 1999-11-23
EP0954284A4 (en) 2000-01-26
ATE301454T1 (de) 2005-08-15
JP4219403B2 (ja) 2009-02-04
JP2000507594A (ja) 2000-06-20
IL117773A0 (en) 1996-08-04
WO1997036577A1 (en) 1997-10-09
DE69733966D1 (de) 2005-09-15
EP0954284A1 (en) 1999-11-10

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