ES227680A2 - UN PROCEDIMIENTO DE PRODUCCIoN DE UNA VACUNA DE VIRUS DE POLIOMIELITIS - Google Patents

UN PROCEDIMIENTO DE PRODUCCIoN DE UNA VACUNA DE VIRUS DE POLIOMIELITIS

Info

Publication number
ES227680A2
ES227680A2 ES0227680A ES227680A ES227680A2 ES 227680 A2 ES227680 A2 ES 227680A2 ES 0227680 A ES0227680 A ES 0227680A ES 227680 A ES227680 A ES 227680A ES 227680 A2 ES227680 A2 ES 227680A2
Authority
ES
Spain
Prior art keywords
deadly
combination
live
aqueous medium
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0227680A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Publication of ES227680A2 publication Critical patent/ES227680A2/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32661—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Mejoras introducidas en el objetos la patente principal, o sea, en un procedimiento para producir una vacuna de virus de la poliomielitis que consiste en someter un medio acuoso que contenga virus de poliomielitis vivos a tratamiento con una combinación de irradiación ultravioleta y formaldehído más calor o irradiación ultravioleta y formaldehído más calor en cualquier orden en condiciones tales que el primer tratamiento mortífero de la combinación sea suficiente para matar una elevada proporción de virus de poliomielitis vivos presentes en el medio acuoso original pero no todo y que el tratamiento o tratamientos mortíferos siguientes de la combinación sean suficientes para matar todos los virus de poliomielitis vivos restantes presentes en el medio, no siendo ninguno de los citados tratamientos mortíferos, aplicado por si solo al medio acuoso original, capaz de matar completamente todos los virus de poliomielitis vivos presentes en el medio.
ES0227680A 1956-02-20 1956-04-03 UN PROCEDIMIENTO DE PRODUCCIoN DE UNA VACUNA DE VIRUS DE POLIOMIELITIS Expired ES227680A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US566374A US3019168A (en) 1956-02-20 1956-02-20 Heat and ultra-violet light attenuation of polio virus

Publications (1)

Publication Number Publication Date
ES227680A2 true ES227680A2 (es) 1956-11-16

Family

ID=24262617

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0227680A Expired ES227680A2 (es) 1956-02-20 1956-04-03 UN PROCEDIMIENTO DE PRODUCCIoN DE UNA VACUNA DE VIRUS DE POLIOMIELITIS

Country Status (2)

Country Link
US (1) US3019168A (es)
ES (1) ES227680A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3208909A (en) * 1961-05-19 1965-09-28 Puziss Milton Anaerobic process for production of a gel-adsorbed anthrax immunizing antigen
US3259546A (en) * 1962-06-01 1966-07-05 Canadian Patents Dev Treatment of viruses
US4305390A (en) * 1975-11-28 1981-12-15 Massachusetts Institute Of Technology Method for generating oxygen in an excited electronic state and inactivation of microorganisms
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
EP3449250B1 (en) 2016-04-28 2020-11-04 Indiana University Research & Technology Corporation Methods and compositions for resolving components of a virus preparation
WO2019060538A1 (en) 2017-09-20 2019-03-28 The Trustees Of Indiana University METHODS FOR LIPOPROTEIN RESOLUTION BY MASS SPECTROMETRY
EP3738137A1 (en) 2018-01-12 2020-11-18 The Trustees of Indiana University Electrostatic linear ion trap design for charge detection mass spectrometry
WO2019236143A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for calibrating or resetting a charge detector
JP7398810B2 (ja) 2018-06-04 2023-12-15 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 静電線形イオン・トラップにイオンを捕獲する装置および方法
CA3100838A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Charge detection mass spectrometry with real time analysis and signal optimization
WO2019236139A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
EP4391015A3 (en) 2018-06-04 2024-10-09 The Trustees of Indiana University Ion trap array for high throughput charge detection mass spectrometry
CN113574632B (zh) 2018-11-20 2024-07-30 印地安纳大学理事会 用于单粒子质谱分析的轨道阱
EP4443473A3 (en) 2018-12-03 2025-01-01 The Trustees of Indiana University Apparatus for simultaneously analyzing multiple ions with an electrostatic linear ion trap
EP3959741A1 (en) 2019-04-23 2022-03-02 The Trustees of Indiana University Identification of sample subspecies based on particle charge behavior under structural change-inducing sample conditions
WO2021061650A1 (en) 2019-09-25 2021-04-01 The Trustees Of Indiana University Apparatus and method for pulsed mode charge detection mass spectrometry
CN114728237B (zh) 2019-10-10 2026-02-24 印地安纳大学理事会 用于识别、选择和纯化粒子的系统和方法
JP7690209B2 (ja) 2019-12-18 2025-06-10 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 電荷測定装置を有する質量分析計
EP4100991B1 (en) 2020-02-03 2025-01-29 The Trustees of Indiana University A charge detection mass spectrometer and related method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191414972A (en) * 1913-06-21 1916-06-22 Otto Stiner An Improved Process for Producing Sera and Vaccines.
US2421382A (en) * 1946-03-06 1947-06-03 Michael Reese Res Foundation Vaccines and antigens and method of producing the same

Also Published As

Publication number Publication date
US3019168A (en) 1962-01-30

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